Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice

Molecular Endocrinology

Volumn 28, Issue 12, 2014, Pages 2038-2048

  Alvarez Perez, Juan C ^a   Rosa, Taylor C ^b   Casinelli, Gabriella P ^b   Valle, Shelley R ^b   Lakshmipathi, Jayalakshmi ^a   Rosselot, Carolina ^a   Rausell Palamos, Francisco ^a   Vasavada, Rupangi C ^a   García Ocaña, Adolfo ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; KI 67 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SCATTER FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PDX 1; INSULIN RECEPTOR SUBSTRATE; IRS2 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ARTICLE; BETA CELL MASS; CELL DEATH; CELL SURVIVAL; CELLULAR PARAMETERS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPOINSULINEMIA; IMMUNOHISTOCHEMISTRY; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INS 1 CELL LINE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS; PHENOTYPE; PREGNANCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; DEFICIENCY; GENETICS; METABOLISM; PANCREAS ISLET BETA CELL; PHYSIOLOGY; TRANSGENIC MOUSE;

MUS;

ANIMALS; HEPATOCYTE GROWTH FACTOR; HYPERGLYCEMIA; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-SECRETING CELLS; MALE; MICE; MICE, TRANSGENIC;

EID: 84914148587     PISSN: 08888809     EISSN: 19449917     Source Type: Journal    
DOI: 10.1210/me.2014-1207     Document Type: Article

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