NTRK3 Is a Potential Tumor Suppressor Gene Commonly Inactivated by Epigenetic Mechanisms in Colorectal Cancer

PLoS Genetics

Volumn 9, Issue 7, 2013, Pages

  Luo, Yanxin ^a,b   Kaz, Andrew M ^b,c,d   Kanngurn, Samornmas ^e   Welsch, Piri ^f   Morris, Shelli M ^b   Wang, Jianping ^a   Lutterbaugh, James D ^g   Markowitz, Sanford D ^g   Grady, William M ^b,d  

^a SUN YAT SEN UNIVERSITY   (China)

^b Fred Hutchinson Cancer Research Center   (United States)

^c VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e PRINCE OF SONGKLA UNIVERSITY   (Thailand)

^f UNIVERSITY OF WASHINGTON   (United States)

^g CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR; NEUROTROPHIN TYROSINE KINASE RECEPTOR 3; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; COLON ADENOCARCINOMA; COLON ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; EPIGENETIC REPRESSION; FEMALE; GENE EXPRESSION; GENE INACTIVATION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; METHYLATION; MOUSE; MUTANT; NONHUMAN; NTRK3 GENE; TUMOR SUPPRESSOR GENE;

AGED; APOPTOSIS; COLORECTAL NEOPLASMS; DNA METHYLATION; EPIGENETIC REPRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; GENOME, HUMAN; HCT116 CELLS; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; POLYSACCHARIDES; PROMOTER REGIONS, GENETIC; RECEPTOR, TRKC;

EID: 84880810108     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003552     Document Type: Article

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