Deletion of Irs2 causes reduced kidney size in mice: Role for inhibition of GSK3?

BMC Developmental Biology

Volumn 10, Issue , 2010, Pages

  Carew, Rosemarie M ^a   Sadagurski, Marianna ^c   Goldschmeding, Roel ^d   Martin, Finian ^a   White, Morris F ^c   Brazil, Derek P ^b  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MUS;

GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INSULIN; INSULIN RECEPTOR SUBSTRATE; IRS2 PROTEIN, MOUSE; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP PROTEIN, MOUSE;

ANIMAL; ARTICLE; FEMALE; GENETICS; GROWTH, DEVELOPMENT AND AGING; KIDNEY; MALE; METABOLISM; MOUSE; ORGAN SIZE; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; FEMALE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; KIDNEY; MALE; MICE; ORGAN SIZE; PHOSPHOPROTEINS; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 77954194860     PISSN: None     EISSN: 1471213X     Source Type: Journal    
DOI: 10.1186/1471-213X-10-73     Document Type: Article

References (47)

1. Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. XJ Sun P Rothenberg CR Kahn JM Backer E Araki PA Wilden DA Cahill BJ Goldstein MF White, Nature 1991 352 73 7 10.1038/352073a0 1648180
2. The insulin signaling system. MF White CR Kahn, J Biol Chem 1994 269 1 4 8276779
3. Mouse models of insulin resistance. A Nandi Y Kitamura CR Kahn D Accili, Physiol Rev 2004 84 623 47 10.1152/physrev.00032.2003 15044684
4. Role of IRS-2 in insulin and cytokine signalling. XJ Sun LM Wang Y Zhang L Yenush MG Myers Jr E Glasheen WS Lane JH Pierce MF White, Nature 1995 377 173 7 10.1038/377173a0 7675087
5. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. E Araki MA Lipes ME Patti JC Bruning B Haag RS Johnson CR Kahn, Nature 1994 372 186 90 10.1038/372186a0 7526222
6. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. H Tamemoto T Kadowaki K Tobe T Yagi H Sakura T Hayakawa Y Terauchi K Ueki Y Kaburagi S Satoh,, et al. Nature 1994 372 182 6 10.1038/372182a0 7969452
7. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. DJ Withers DJ Burks HH Towery SL Altamuro CL Flint MF White, Nat Genet 1999 23 32 40 10471495
8. Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. N Kubota K Tobe Y Terauchi K Eto T Yamauchi R Suzuki Y Tsubamoto K Komeda R Nakano H Miki,, et al. Diabetes 2000 49 1880 9 10.2337/diabetes.49.11.1880 11078455
9. Disruption of IRS-2 causes type 2 diabetes in mice. DJ Withers JS Gutierrez H Towery DJ Burks JM Ren S Previs Y Zhang D Bernal S Pons GI Shulman,, et al. Nature 1998 391 900 4 10.1038/36116 9495343
10. Size control in animal development. I Conlon M Raff, Cell 1999 96 235 44 10.1016/S0092-8674(00)80563-2 9988218
11. Control of growth and development of the feto-placental unit. VK Han AM Carter, Curr Opin Pharmacol 2001 1 632 40 10.1016/S1471-4892(01)00108-4 11757820
12. Biological effects of growth hormone and its antagonist. S Okada JJ Kopchick, Trends Mol Med 2001 7 126 32 10.1016/S1471-4914(01)01933-5 11286784
13. Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. D Accili J Drago EJ Lee MD Johnson MH Cool P Salvatore LD Asico PA Jose SI Taylor H Westphal, Nat Genet 1996 12 106 9 10.1038/ng0196-106 8528241
14. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). JP Liu J Baker AS Perkins EJ Robertson A Efstratiadis, Cell 1993 75 59 72 8402901
15. Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development. A Louvi D Accili A Efstratiadis, Dev Biol 1997 189 33 48 10.1006/dbio.1997.8666 9281335
16. Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells. X Yi M Schubert NS Peachey K Suzuma DJ Burks JA Kushner I Suzuma C Cahill CL Flint MA Dow,, et al. J Neurosci 2005 25 1240 8 10.1523/JNEUROSCI.3664-04.2005 15689562
17. Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation. M Schubert DP Brazil DJ Burks JA Kushner J Ye CL Flint J Farhang-Fallah P Dikkes XM Warot C Rio,, et al. J Neurosci 2003 23 7084 92 12904469
18. Insulin enhances sodium sensitivity of Na-K-ATPase in isolated rat proximal convoluted tubule. E Feraille ML Carranza M Rousselot H Favre, Am J Physiol 1994 267 55 62 8048565
19. Insulin stimulates NaCl transport in isolated perfused MTAL of Henle's loop of rabbit kidney. O Ito Y Kondo N Takahashi K Kudo Y Igarashi K Omata Y Imai K Abe, Am J Physiol 1994 267 265 70 8067387
20. Insulin activates Na(+)/H(+) exchanger 3: biphasic response and glucocorticoid dependence. J Klisic MC Hu V Nief L Reyes D Fuster OW Moe PM Ambuhl, Am J Physiol Renal Physiol 2002 283 532 9 12167605
21. Insulin activates single amiloride-blockable Na channels in a distal nephron cell line (A6). Y Marunaka N Hagiwara H Tohda, Am J Physiol 1992 263 392 400 1329533
22. Insulin binding sites in various segments of the rabbit nephron. R Nakamura DS Emmanouel AI Katz, J Clin Invest 1983 72 388 92 10.1172/JCI110979 6348088
23. Regulation of the renal Na-HCO3 cotransporter: IX. Modulation by insulin, epidermal growth factor and carbachol. OS Ruiz YY Qiu LR Cardoso JA Arruda, Regul Pept 1998 77 155 61 10.1016/S0167-0115(98)00115-3 9809810
24. Roles of insulin receptor substrates in insulin-induced stimulation of renal proximal bicarbonate absorption. Y Zheng H Yamada K Sakamoto S Horita M Kunimi Y Endo Y Li K Tobe Y Terauchi T Kadowaki,, et al. J Am Soc Nephrol 2005 16 2288 95 10.1681/ASN.2005020193 15975995
25. Role of insulin and the IGF system in renal hypertrophy in diabetic Psammomys obesus (sand rat). I Raz I Wexler O Weiss A Flyvbjerg Y Segev A Rauchwerger G Raz M Khamaisi, Nephrol Dial Transplant 2003 18 1293 8 10.1093/ndt/gfg170 12808164
26. Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. AV Bakin AK Tomlinson NA Bhowmick HL Moses CL Arteaga, J Biol Chem 2000 275 36803 10 10.1074/jbc.M005912200 10969078
27. TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells. E Piek A Moustakas A Kurisaki CH Heldin P ten Dijke, Book TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells 1999 112 4557 4568
28. Snail is required for transforming growth factor-beta-induced epithelial-mesenchymal transition by activating PI3 kinase/Akt signal pathway. HJ Cho KE Baek S Saika MJ Jeong J Yoo, Biochem Biophys Res Commun 2007 353 337 43 10.1016/j.bbrc.2006.12.035 17187756
29. Protein kinase B/Akt activity is involved in renal TGF{beta}-1 driven epithelial-mesenchymal transition in vitro and in vivo. JJ Kattla RM Carew M Heljic C Godson DP Brazil, Am J Physiol Renal Physiol 2008 18495798
30. YAP1 increases organ size and expands undifferentiated progenitor cells. FD Camargo S Gokhale JB Johnnidis D Fu GW Bell R Jaenisch TR Brummelkamp, Curr Biol 2007 17 2054 60 10.1016/j.cub.2007.10.039 17980593
31. Elucidation of a universal size-control mechanism in Drosophila and mammals. J Dong G Feldmann J Huang Wu S N Zhang SA Comerford MF Gayyed RA Anders A Maitra D Pan, Cell 2007 130 1120 33 10.1016/j.cell.2007.07.019 17889654
32. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. B Zhao X Wei W Li RS Udan Q Yang J Kim J Xie T Ikenoue J Yu L Li,, et al. Genes Dev 2007 21 2747 61 10.1101/gad.1602907 17974916
33. Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. S Basu NF Totty MS Irwin M Sudol J Downward, Mol Cell 2003 11 11 23 10.1016/S1097-2765(02)00776-1 12535517
34. IRS-2 pathways integrate female reproduction and energy homeostasis. DJ Burks J Font de Mora M Schubert DJ Withers MG Myers HH Towery SL Altamuro CL Flint MF White, Nature 2000 407 377 82 10.1038/35030105 11014193
35. Postnatal growth responses to insulin-like growth factor I in insulin receptor substrate-1-deficient mice. G Pete CR Fuller JM Oldham DR Smith AJ D'Ercole CR Kahn PK Lund, Endocrinology 1999 140 5478 87 10.1210/en.140.12.5478 10579310
36. AKT1, AKT2 and AKT3-dependent cell survival is cell line-specific and knockdown of all three isoforms selectively induces apoptosis in 20 human tumor cell lines. S Koseoglu Z Lu C Kumar P Kirschmeier J Zou, Cancer Biol Ther 2007 6 755 62 10.4161/cbt.6.5.3995 17426444
37. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. DD Sarbassov DA Guertin Ali SM DM Sabatini, Science 2005 307 1098 101 10.1126/science.1106148 15718470
38. mTOR complex 2 in adipose tissue negatively controls whole-body growth. N Cybulski P Polak J Auwerx MA Rüegg MN Hall, Proc Natl Acad Sci USA 2009 106 9902 7 10.1073/pnas.0811321106 19497867
39. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. DA Cross DR Alessi P Cohen M Andjelkovich BA Hemmings, Nature 1995 378 785 9 10.1038/378785a0 8524413
40. The renaissance of GSK3. P Cohen S Frame, Nat Rev Mol Cell Biol 2001 2 769 76 10.1038/35096075 11584304
41. Functional interaction of beta-catenin with the transcription factor LEF-1. J Behrens JP von Kries M Kuhl L Bruhn D Wedlich R Grosschedl W Birchmeier, Nature 1996 382 638 42 10.1038/382638a0 8757136
42. Identification of c-MYC as a target of the APC pathway. TC He AB Sparks C Rago H Hermeking L Zawel LT da Costa PJ Morin B Vogelstein KW Kinzler, Science 1998 281 1509 12 10.1126/science.281.5382.1509 9727977
43. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. O Tetsu F McCormick, Nature 1999 398 422 6 10.1038/18884 10201372
44. From cell structure to transcription: Hippo forges a new path. BA Edgar, Cell 2006 124 267 73 10.1016/j.cell.2006.01.005 16439203
45. The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. K Harvey N Tapon, Nat Rev Cancer 2007 7 182 91 10.1038/nrc2070 17318211
46. Hippo signaling in organ size control. D Pan, Genes Dev 2007 21 886 97 10.1101/gad.1536007 17437995
47. A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. R Yagi LF Chen K Shigesada Y Murakami Y Ito, Embo J 1999 18 2551 62 10.1093/emboj/18.9.2551 10228168