-
1
-
-
52149084405
-
Explaining human uniqueness: Genome interactions with environment, behaviour and culture
-
A. Varki, D. H. Geschwind, E. E. Eichler, Explaining human uniqueness: Genome interactions with environment, behaviour and culture. Nat. Rev. Genet. 9, 749-763 (2008).
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 749-763
-
-
Varki, A.1
Geschwind, D.H.2
Eichler, E.E.3
-
2
-
-
37648999313
-
Distinguishing protein-coding and noncoding genes in the human genome
-
M. Clamp, B. Fry, M. Kamal, X. Xie, J. Cuff, M. F. Lin, M. Kellis, K. Lindblad-Toh, E. S. Lander, Distinguishing protein-coding and noncoding genes in the human genome. Proc. Natl. Acad. Sci. U.S.A. 104, 19428-19433 (2007).
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 19428-19433
-
-
Clamp, M.1
Fry, B.2
Kamal, M.3
Xie, X.4
Cuff, J.5
Lin, M.F.6
Kellis, M.7
Lindblad-Toh, K.8
Lander, E.S.9
-
3
-
-
33751329250
-
Global variation in copy number in the human genome
-
DOI 10.1038/nature05329, PII NATURE05329
-
R. Redon, S. Ishikawa, K. R. Fitch, L. Feuk, G. H. Perry, T. D. Andrews, H. Fiegler, M. H. Shapero, A. R. Carson, W. Chen, E. K. Cho, S. Dallaire, J. L. Freeman, J. R. Gonzalez, M. Gratacos, J. Huang, D. Kalaitzopoulos, D. Komura, J. R. MacDonald, C. R. Marshall, R. Mei, L. Montgomery, K. Nishimura, K. Okamura, F. Shen, M. J. Somerville, J. Tchinda, A. Valsesia, C.Woodwark, F. Yang, J. Zhang, T. Zerjal, J. Zhang, L. Armengol, E. F. Conrad, X. Estivill, C. Tyler-Smith, N. P. Carter, H. Aburatani, C. Lee, K. W. Jones, S. W. Scherer, M. E. Hurles, Global variation in copy number in the human genome. Nature 444, 444-454 (2006). (Pubitemid 44809057)
-
(2006)
Nature
, vol.444
, Issue.7118
, pp. 444-454
-
-
Redon, R.1
Ishikawa, S.2
Fitch, K.R.3
Feuk, L.4
Perry, G.H.5
Andrews, T.D.6
Fiegler, H.7
Shapero, M.H.8
Carson, A.R.9
Chen, W.10
Cho, E.K.11
Dallaire, S.12
Freeman, J.L.13
Gonzalez, J.R.14
Gratacos, M.15
Huang, J.16
Kalaitzopoulos, D.17
Komura, D.18
MacDonald, J.R.19
Marshall, C.R.20
Mei, R.21
Montgomery, L.22
Nishimura, K.23
Okamura, K.24
Shen, F.25
Somerville, M.J.26
Tchinda, J.27
Valsesia, A.28
Woodwark, C.29
Yang, F.30
Zhang, J.31
Zerjal, T.32
Zhang, J.33
Armengol, L.34
Conrad, D.F.35
Estivill, X.36
Tyler-Smith, C.37
Carter, N.P.38
Aburatani, H.39
Lee, C.40
Jones, K.W.41
Scherer, S.W.42
Hurles, M.E.43
more..
-
4
-
-
33745373606
-
Primate segmental duplications: Crucibles of evolution, diversity and disease
-
J. A. Bailey, E. E. Eichler, Primate segmental duplications: Crucibles of evolution, diversity and disease. Nat. Rev. Genet. 7, 552-564 (2006).
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 552-564
-
-
Bailey, J.A.1
Eichler, E.E.2
-
5
-
-
33846978695
-
Relative impact of nucleotide and copy number variation on gene expression phenotypes
-
B. E. Stranger, M. S. Forrest, M. Dunning, C. E. Ingle, C. Beazley, N. Thorne, R. Redon, C. P. Bird, A. de Grassi, C. Lee, C. Tyler-Smith, N. Carter, S. W. Scherer, S. Tavare, P. Deloukas, M. E. Hurles, E. T. Dermitzakis, Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 315, 848-853 (2007).
-
(2007)
Science
, vol.315
, pp. 848-853
-
-
Stranger, B.E.1
Forrest, M.S.2
Dunning, M.3
Ingle, C.E.4
Beazley, C.5
Thorne, N.6
Redon, R.7
Bird, C.P.8
De Grassi, A.9
Lee, C.10
Tyler-Smith, C.11
Carter, N.12
Scherer, S.W.13
Tavare, S.14
Deloukas, P.15
Hurles, M.E.16
Dermitzakis, E.T.17
-
6
-
-
33846326304
-
Genetic screening for signal transduction in the era of network biology
-
A. Friedman, N. Perrimon, Genetic screening for signal transduction in the era of network biology. Cell 128, 225-231 (2007).
-
(2007)
Cell
, vol.128
, pp. 225-231
-
-
Friedman, A.1
Perrimon, N.2
-
7
-
-
3042848952
-
Evidence for dynamically organized modularity in the yeast proteinprotein interaction network
-
J. D. Han, N. Bertin, T. Hao, D. S. Goldberg, G. F. Berriz, L. V. Zhang, D. Dupuy, A. J.Walhout, M. E. Cusick, F. P. Roth, M. Vidal, Evidence for dynamically organized modularity in the yeast proteinprotein interaction network. Nature 430, 88-93 (2004).
-
(2004)
Nature
, vol.430
, pp. 88-93
-
-
Han, J.D.1
Bertin, N.2
Hao, T.3
Goldberg, D.S.4
Berriz, G.F.5
Zhang, L.V.6
Dupuy, D.7
Walhout, A.J.8
Cusick, M.E.9
Roth, F.P.10
Vidal, M.11
-
8
-
-
39749142228
-
The search for new cardiovascular biomarkers
-
R. E. Gerszten, T. J. Wang, The search for new cardiovascular biomarkers. Nature 451, 949-952 (2008).
-
(2008)
Nature
, vol.451
, pp. 949-952
-
-
Gerszten, R.E.1
Wang, T.J.2
-
9
-
-
46749110040
-
Mapping the human protein interactome
-
D. Figeys, Mapping the human protein interactome. Cell Res. 18, 716-724 (2008).
-
(2008)
Cell Res.
, vol.18
, pp. 716-724
-
-
Figeys, D.1
-
10
-
-
33748675254
-
An RNA gene expressed during cortical development evolved rapidly in humans
-
K. S. Pollard, S. R. Salama, N. Lambert, M. A. Lambot, S. Coppens, J. S. Pedersen, S. Katzman, B. King, C. Onodera, A. Siepel, A. D. Kern, C. Dehay, H. Igel, M. Ares Jr., P. Vanderhaeghen, D. Haussler, An RNA gene expressed during cortical development evolved rapidly in humans. Nature 443, 167-172 (2006).
-
(2006)
Nature
, vol.443
, pp. 167-172
-
-
Pollard, K.S.1
Salama, S.R.2
Lambert, N.3
Lambot, M.A.4
Coppens, S.5
Pedersen, J.S.6
Katzman, S.7
King, B.8
Onodera, C.9
Siepel, A.10
Kern, A.D.11
Dehay, C.12
Igel, H.13
Ares Jr., M.14
Vanderhaeghen, P.15
Haussler, D.16
-
11
-
-
33744734662
-
Origination and evolution of a human- specific transmembrane protein gene, c1orf37-dup
-
H.Yu, H. Jiang, Q. Zhou, J.Yang, Y. Cun, B. Su, C. Xiao, W.Wang, Origination and evolution of a human- specific transmembrane protein gene, c1orf37-dup. Hum. Mol. Genet. 15, 1870-1875 (2006).
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1870-1875
-
-
Yu, H.1
Jiang, H.2
Zhou, Q.3
Yang, J.4
Cun, Y.5
Su, B.6
Xiao, C.7
Wang W8
-
12
-
-
26444529054
-
A novel gene family NBPF: Intricate structure generated by gene duplications during primate evolution
-
K. Vandepoele, N. Van Roy, K. Staes, F. Speleman, F. van Roy, A novel gene family NBPF: Intricate structure generated by gene duplications during primate evolution. Mol. Biol. Evol. 22, 2265-2274 (2005).
-
(2005)
Mol. Biol. Evol.
, vol.22
, pp. 2265-2274
-
-
Vandepoele, K.1
Van Roy, N.2
Staes, K.3
Speleman, F.4
Van Roy, F.5
-
13
-
-
67649289900
-
Copy number variation at 1q21.1 associated with neuroblastoma
-
S. J. Diskin, C. Hou, J. T. Glessner, E. F. Attiyeh, M. Laudenslager, K. Bosse, K. Cole, Y. P. Mosse, A. Wood, J. E. Lynch, K. Pecor, M. Diamond, C. Winter, K. Wang, C. Kim, E. A. Geiger, P. W. Mc- Grady, A. I. Blakemore, W. B. London, T. H. Shaikh, J. Bradfield, S. F. Grant, H. Li, M. Devoto, E. R. Rappaport, H. Hakonarson, J. M. Maris, Copy number variation at 1q21.1 associated with neuroblastoma. Nature 459, 987-991 (2009).
-
(2009)
Nature
, vol.459
, pp. 987-991
-
-
Diskin, S.J.1
Hou, S.J.2
Glessner, J.T.3
Attiyeh, E.F.4
Laudenslager, M.5
Bosse, K.6
Cole, K.7
Mosse, Y.P.8
Wood, A.9
Lynch, J.E.10
Pecor, K.11
Diamond, M.12
Winter, C.13
Wang, K.14
Kim, C.15
Geiger, E.A.16
Mc-Grady, P.W.17
Blakemore, A.I.18
London, W.B.19
Shaikh, T.H.20
Bradfield, J.21
Grant, S.F.22
Li, H.23
Devoto, M.24
Rappaport, E.R.25
Hakonarson, H.26
Maris, J.M.27
more..
-
14
-
-
33748292822
-
Human lineage-specific amplification, selection, and neuronal expression of DUF1220 domains
-
M. C. Popesco, E. J. Maclaren, J. Hopkins, L. Dumas, M. Cox, L. Meltesen, L. McGavran, G. J. Wyckoff, J. M. Sikela, Human lineage-specific amplification, selection, and neuronal expression of DUF1220 domains. Science 313, 1304-1307 (2006).
-
(2006)
Science
, vol.313
, pp. 1304-1307
-
-
Popesco, M.C.1
Maclaren, E.J.2
Hopkins, J.3
Dumas, L.4
Cox, M.5
Meltesen, L.6
McGavran, L.7
Wyckoff, G.J.8
Sikela, J.M.9
-
15
-
-
0035807336
-
Positive selection of a gene family during the emergence of humans and African apes
-
M. E. Johnson, L. Viggiano, J. A. Bailey, M. Abdul- Rauf, G. Goodwin, M. Rocchi, E. E. Eichler, Positive selection of a gene family during the emergence of humans and African apes. Nature 413, 514-519 (2001).
-
(2001)
Nature
, vol.413
, pp. 514-519
-
-
Johnson, M.E.1
Viggiano, L.2
Bailey, J.A.3
Abdul-Rauf, M.4
Goodwin, G.5
Rocchi, M.6
Eichler, E.E.7
-
16
-
-
38549126058
-
Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling
-
D. M. Hornan, S. N. Peirson, A. J. Hardcastle, R. S. Molday, M. E. Cheetham, A. R.Webster, Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling. Invest. Ophthalmol. Vis. Sci. 48, 5388-5396 (2007).
-
(2007)
Invest. Ophthalmol. Vis. Sci.
, vol.48
, pp. 5388-5396
-
-
Hornan, D.M.1
Peirson, S.N.2
Hardcastle, A.J.3
Molday, R.S.4
Cheetham, M.E.5
Webster, A.R.6
-
17
-
-
44949237183
-
The primate-specific protein TBC1D3 is required for optimal macropinocytosis in a novel ARF6-dependent pathway
-
E. Frittoli, A. Palamidessi, A. Pizzigoni, L. Lanzetti, M. Garre, F. Troglio, A. Troilo, M. Fukuda, P. P. Di Fiore, G. Scita, S. Confalonieri, The primate-specific protein TBC1D3 is required for optimal macropinocytosis in a novel ARF6-dependent pathway. Mol. Biol. Cell 19, 1304-1316 (2008).
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 1304-1316
-
-
Frittoli, E.1
Palamidessi, A.2
Pizzigoni, A.3
Lanzetti, L.4
Garre, M.5
Troglio, F.6
Troilo, A.7
Fukuda, M.8
Di Fiore, P.P.9
Scita, G.10
Confalonieri S11
-
18
-
-
45149120246
-
The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking
-
M. J.Wainszelbaum, A. J. Charron, C. Kong, D. S. Kirkpatrick, P. Srikanth, M. A. Barbieri, S. P. Gygi, P. D. Stahl, The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking. J. Biol. Chem. 283, 13233-13242 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13233-13242
-
-
Wainszelbaum, M.J.1
Charron, A.J.2
Kong, C.3
Kirkpatrick, D.S.4
Srikanth, P.5
Barbieri, M.A.6
Gygi, S.P.7
Stahl, P.D.8
-
19
-
-
33750937409
-
TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12
-
D. Hodzic, C. Kong, M. J. Wainszelbaum, A. J. Charron, X. Su, P. D. Stahl, TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12. Genomics 88, 731-736 (2006).
-
(2006)
Genomics
, vol.88
, pp. 731-736
-
-
Hodzic, D.1
Kong, C.2
Wainszelbaum, M.J.3
Charron, A.J.4
Su, X.5
Stahl, P.D.6
-
20
-
-
0023756050
-
A rearranged transforming gene, tre, is made up of human sequences derived from chromosome regions 5q, 17q and 18q
-
K. Huebner, L. A. Cannizzaro, T. Nakamura, J. Hillova, R. Mariage-Samson, F. Hecht, M. Hill, C. M. Croce, A rearranged transforming gene, tre, is made up of human sequences derived from chromosome regions 5q, 17q and 18q. Oncogene 3, 449-455 (1988).
-
(1988)
Oncogene
, vol.3
, pp. 449-455
-
-
Huebner, K.1
Cannizzaro, L.A.2
Nakamura, T.3
Hillova, J.4
Mariage-Samson, R.5
Hecht, F.6
Hill, M.7
Croce, C.M.8
-
22
-
-
0036791144
-
PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer
-
L. Pei, Y. Peng, Y.Yang, X. B. Ling, W. G. Van Eyndhoven, K. C. Nguyen, M. Rubin, T. Hoey, S. Powers, J. Li, PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. Cancer Res. 62, 5420-5424 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 5420-5424
-
-
Pei, L.1
Peng, Y.2
Yang, Y.3
Ling, X.B.4
Van Eyndhoven, W.G.5
Nguyen, K.C.6
Rubin, M.7
Hoey, T.8
Powers, S.9
Li, J.10
-
23
-
-
33646184682
-
DNA sequence of human chromosome and analysis of rearrangement in the human lineage
-
M. C. Zody, M. Garber, D. J. Adams, T. Sharpe, J. Harrow, J. R. Lupski, C. Nicholson, S. M. Searle, L. Wilming, S. K.Young, A. Abouelleil, N. R. Allen, W. Bi, T. Bloom, M. L. Borowsky, B. E. Bugalter, J. Butler, J. L. Chang, C. K. Chen, A. Cook, B. Corum, C. A. Cuomo, P. J. de Jong, D. DeCaprio, K. Dewar, M. FitzGerald, J. Gilbert, R. Gibson, S. Gnerre, S. Goldstein, D. V. Grafham, R. Grocock, N. Hafez, D. S. Hagopian, E. Hart, C. H. Norman, S. Humphray, D. B. Jaffe, M. Jones, M. Kamal, V. K. Khodiyar, K. LaButti, G. Laird, J. Lehoczky, X. Liu, T. Lokyitsang, J. Loveland, A. Lui, P. Macdonald, J. E. Major, L. Matthews, E. Mauceli, S. A. McCarroll, A. H. Mihalev, J. Mudge, C. Nguyen, R. Nicol, S. B. O'Leary, K. Osoegawa, D. C. Schwartz, C. Shaw-Smith, P. Stankiewicz, C. Steward, D. Swarbreck, V. Venkataraman, C. A. Whittaker, X. Yang, A. R. Zimmer, A. Bradley, T. Hubbard, B.W. Birren, J. Rogers, E. S. Lander, C. Nusbaum, DNA sequence of human chromosome and analysis of rearrangement in the human lineage. Nature 440, 1045-1049 (2006).
-
(2006)
Nature
, vol.440
, pp. 1045-1049
-
-
Zody, M.C.1
Garber, M.2
Adams, D.J.3
Sharpe, T.4
Harrow, J.5
Lupski, J.R.6
Nicholson, C.7
Searle, S.M.8
Wilming, L.9
Young, S.K.10
Abouelleil, A.11
Allen, N.R.12
Bi, W.13
Bloom, T.14
Borowsky, M.L.15
Bugalter, B.E.16
Butler, J.17
Chang, J.L.18
Chen, C.K.19
Cook, A.20
Corum, B.21
Cuomo, C.A.22
De Jong, P.J.23
De Caprio, D.24
Dewar, K.25
FitzGerald, M.26
Gilbert, J.27
Gibson, R.28
Gnerre, S.29
Goldstein, S.30
Grafham, D.V.31
Grocock, R.32
Hafez, N.33
Hagopian, D.S.34
Hart, E.35
Norman, C.H.36
Humphray, S.37
Jaffe, D.B.38
Jones, M.39
Kamal, M.40
Khodiyar, V.K.41
LaButti, K.42
Laird, G.43
Lehoczky, J.44
Liu, X.45
Lokyitsang, T.46
Loveland, J.47
Lui, A.48
Macdonald, P.49
Major, J.E.50
Matthews, L.51
Mauceli, E.52
McCarroll, S.A.53
Mihalev, A.H.54
Mudge, J.55
Nguyen, C.56
Nicol, R.57
O'Leary, S.B.58
Osoegawa, K.59
Schwartz, D.C.60
Shaw-Smith, C.61
Stankiewicz, P.62
Steward, C.63
Swarbreck, D.64
Venkataraman, V.65
Whittaker, C.A.66
Yang, X.67
Zimmer, A.R.68
Bradley, A.69
Hubbard, T.70
Birren, B.W.71
Rogers, J.72
Lander, E.S.73
Nusbaum, C.74
more..
-
24
-
-
55549143682
-
Copy number variation and evolution in humans and chimpanzees
-
G. H. Perry, F.Yang, T. Marques-Bonet, C. Murphy, T. Fitzgerald, A. S. Lee, C. Hyland, A. C. Stone, M. E. Hurles, C. Tyler-Smith, E. E. Eichler, N. P. Carter, C. Lee, R. Redon, Copy number variation and evolution in humans and chimpanzees. Genome Res. 18, 1698-1710 (2008).
-
(2008)
Genome Res.
, vol.18
, pp. 1698-1710
-
-
Perry, G.H.1
Yang, F.2
Marques-Bonet, F.3
Murphy, F.4
Fitzgerald, T.5
Lee, A.S.6
Hyland, C.7
Stone, A.C.8
Hurles, M.E.9
Tyler-Smith, M.E.10
Eichler, E.E.11
Carter, N.P.12
Lee, C.13
Redon, R.14
-
25
-
-
77953662372
-
-
for invaluable discussions. We also thank D. Owyoung and J. Francis for help with editing. This work was supported by NIH grant GM42259 and support from the Washington University School of Medicine
-
The authors thank M. Brent, X. Su, T. Brett, and H. Piwnica-Worms for helpful comments and C. Kong and P. Srikanth for invaluable discussions. We also thank D. Owyoung and J. Francis for help with editing. This work was supported by NIH grant GM42259 and support from the Washington University School of Medicine.
-
-
-
Brent, M.1
Su, X.2
Brett, T.3
Piwnica-Worms, H.4
Kong, H.5
Srikanth, P.6
|