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Volumn 36, Issue 2, 2013, Pages 177-184

TrkC promotes survival and growth of leukemia cells through akt-mtor-dependent up-regulation of PLK-1 and Twist-1

Author keywords

Apoptosis; Hematological Malignancies; Pi3k akt mtor; Survival And Growth; Trkc

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; NEUROTROPHIN 3 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; POLO LIKE KINASE 1; PROTEIN KINASE B; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR TWIST;

EID: 84892999662     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-013-0061-6     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 3042699439 scopus 로고    scopus 로고
    • Correlations among neural cell adhesion molecule, nerve growth factor, and its receptors, TrkA, TrkB, TrkC, and p75, in perineural invasion by basal cell and cutaneous squamous cell carcinomas
    • Chen-Tsai, C.P., Colome-Grimmer, M., and Wagner, R.F., Jr. (2004). Correlations among neural cell adhesion molecule, nerve growth factor, and its receptors, TrkA, TrkB, TrkC, and p75, in perineural invasion by basal cell and cutaneous squamous cell carcinomas. Dermatol. Surg. 30, 1009-1016.
    • (2004) Dermatol. Surg , vol.30 , pp. 1009-1016
    • Chen-Tsai, C.P.1    Colome-Grimmer, M.2    Wagner Jr., R.F.3
  • 2
    • 33947192053 scopus 로고    scopus 로고
    • Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
    • Cheng, G.Z., Chan, J., Wang, Q., Zhang, W., Sun, C.D., and Wang, L.H. (2007). Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res. 67, 1979-1987.
    • (2007) Cancer Res , vol.67 , pp. 1979-1987
    • Cheng, G.Z.1    Chan, J.2    Wang, Q.3    Zhang, W.4    Sun, C.D.5    Wang, L.H.6
  • 3
    • 28544448340 scopus 로고    scopus 로고
    • Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapyrelated myelodysplasia and acute myeloid leukemia
    • Christiansen, D.H., Andersen, M.K., Desta, F., and Pedersen-Bjergaard, J. (2005). Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapyrelated myelodysplasia and acute myeloid leukemia. Leukemia 19, 2232-2240.
    • (2005) Leukemia , vol.19 , pp. 2232-2240
    • Christiansen, D.H.1    Andersen, M.K.2    Desta, F.3    Pedersen-Bjergaard, J.4
  • 5
    • 0029129034 scopus 로고
    • Mutations in the gene for the granulocyte colonystimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia
    • Dong, F., Brynes, R.K., Tidow, N., Welte, K., Lowenberg, B., and Touw, I.P. (1995). Mutations in the gene for the granulocyte colonystimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia. N. Engl. J. Med. 333, 487-493.
    • (1995) N. Engl. J. Med , vol.333 , pp. 487-493
    • Dong, F.1    Brynes, R.K.2    Tidow, N.3    Welte, K.4    Lowenberg, B.5    Touw, I.P.6
  • 8
    • 84864080019 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion
    • Fenouille, N., Tichet, M., Dufies, M., Pottier, A., Mogha, A., Soo, J.K., Rocchi, S., Mallavialle, A., Galibert, M.D., Khammari, A., et al. (2012). The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion. PLoS One 7, e40378.
    • (2012) PLoS One , vol.7
    • Fenouille, N.1    Tichet, M.2    Dufies, M.3    Pottier, A.4    Mogha, A.5    Soo, J.K.6    Rocchi, S.7    Mallavialle, A.8    Galibert, M.D.9    Khammari, A.10
  • 11
    • 77955134007 scopus 로고    scopus 로고
    • Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: Report from the International Microarray Innovations in Leukemia Study Group
    • Haferlach, T., Kohlmann, A., Wieczorek, L., Basso, G., Kronnie, G.T., Bene, M.C., De Vos, J., Hernandez, J.M., Hofmann, W.K., Mills, K.I., et al. (2010). Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group. J. Clin. Oncol. 28, 2529-2537.
    • (2010) J. Clin. Oncol , vol.28 , pp. 2529-2537
    • Haferlach, T.1    Kohlmann, A.2    Wieczorek, L.3    Basso, G.4    Kronnie, G.T.5    Bene, M.C.6    De Vos, J.7    Hernandez, J.M.8    Hofmann, W.K.9    Mills, K.I.10
  • 13
    • 0036059012 scopus 로고    scopus 로고
    • Gene expression of TrkC (NTRK3) in human soft tissue tumours
    • Hisaoka, M., Sheng, W.Q., Tanaka, A., and Hashimoto, H. (2002). Gene expression of TrkC (NTRK3) in human soft tissue tumours. J. Pathol. 197, 661-667.
    • (2002) J. Pathol , vol.197 , pp. 661-667
    • Hisaoka, M.1    Sheng, W.Q.2    Tanaka, A.3    Hashimoto, H.4
  • 14
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • Huang, E.J., and Reichardt, L.F. (2003). Trk receptors: roles in neuronal signal transduction. Ann. Rev. Biochem. 72, 609-642.
    • (2003) Ann. Rev. Biochem , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 16
    • 35448957195 scopus 로고    scopus 로고
    • TrkC binds to the bone morphogenetic protein type II receptor to suppress bone morphogenetic protein signaling
    • Jin, W., Yun, C., Kim, H.S., and Kim, S.J. (2007). TrkC binds to the bone morphogenetic protein type II receptor to suppress bone morphogenetic protein signaling. Cancer Res. 67, 9869-9877.
    • (2007) Cancer Res , vol.67 , pp. 9869-9877
    • Jin, W.1    Yun, C.2    Kim, H.S.3    Kim, S.J.4
  • 18
    • 79952185501 scopus 로고    scopus 로고
    • DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma
    • Jin, W., Lee, J.J., Kim, M.S., Son, B.H., Cho, Y.K., and Kim, H.P. (2011). DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma. Biochem. Biophys. Res. Commun. 406, 89-95.
    • (2011) Biochem. Biophys. Res. Commun , vol.406 , pp. 89-95
    • Jin, W.1    Lee, J.J.2    Kim, M.S.3    Son, B.H.4    Cho, Y.K.5    Kim, H.P.6
  • 19
    • 0031686409 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
    • Kiyoi, H., Towatari, M., Yokota, S., Hamaguchi, M., Ohno, R., Saito, H., and Naoe, T. (1998). Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. Leukemia 12, 1333-1337.
    • (1998) Leukemia , vol.12 , pp. 1333-1337
    • Kiyoi, H.1    Towatari, M.2    Yokota, S.3    Hamaguchi, M.4    Ohno, R.5    Saito, H.6    Naoe, T.7
  • 22
    • 0034678609 scopus 로고    scopus 로고
    • Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15) (p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia
    • Liu, Q., Schwaller, J., Kutok, J., Cain, D., Aster, J.C., Williams, I.R., and Gilliland, D.G. (2000). Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15) (p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. EMBO J. 19, 1827-1838.
    • (2000) EMBO J , vol.19 , pp. 1827-1838
    • Liu, Q.1    Schwaller, J.2    Kutok, J.3    Cain, D.4    Aster, J.C.5    Williams, I.R.6    Gilliland, D.G.7
  • 24
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • Manning, B.D., and Cantley, L.C. (2007). AKT/PKB signaling: navigating downstream. Cell 129, 1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 26
    • 0037513474 scopus 로고    scopus 로고
    • Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: Its significance as a prognostic variable
    • Min, Y.H., Eom, J.I., Cheong, J.W., Maeng, H.O., Kim, J.Y., Jeung, H.K., Lee, S.T., Lee, M.H., Hahn, J.S., and Ko, Y.W. (2003). Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable. Leukemia 17, 995-997.
    • (2003) Leukemia , vol.17 , pp. 995-997
    • Min, Y.H.1    Eom, J.I.2    Cheong, J.W.3    Maeng, H.O.4    Kim, J.Y.5    Jeung, H.K.6    Lee, S.T.7    Lee, M.H.8    Hahn, J.S.9    Ko, Y.W.10
  • 32
    • 0042357460 scopus 로고    scopus 로고
    • Selectivity in neurotrophin signaling: Theme and variations
    • Segal, R.A. (2003). Selectivity in neurotrophin signaling: theme and variations. Ann. Rev. Neurosci. 26, 299-330.
    • (2003) Ann. Rev. Neurosci , vol.26 , pp. 299-330
    • Segal, R.A.1
  • 33
    • 0028568009 scopus 로고
    • Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma
    • Segal, R.A., Goumnerova, L.C., Kwon, Y.K., Stiles, C.D., and Pomeroy, S.L. (1994). Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc. Natl. Acad. Sci. USA 91, 12867-12871.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12867-12871
    • Segal, R.A.1    Goumnerova, L.C.2    Kwon, Y.K.3    Stiles, C.D.4    Pomeroy, S.L.5
  • 34
    • 33344471932 scopus 로고    scopus 로고
    • KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese
    • Childhood AML Cooperative Study Group
    • Shimada, A., Taki, T., Tabuchi, K., Tawa, A., Horibe, K., Tsuchida, M., Hanada, R., Tsukimoto, I., and Hayashi, Y. (2006). KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group. Blood 107, 1806-1809.
    • (2006) Blood , vol.107 , pp. 1806-1809
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Tawa, A.4    Horibe, K.5    Tsuchida, M.6    Hanada, R.7    Tsukimoto, I.8    Hayashi, Y.9
  • 35
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/ PKB signaling pathway and cell survival
    • Song, G., Ouyang, G., and Bao, S. (2005). The activation of Akt/ PKB signaling pathway and cell survival. J. Cell. Mol. Med. 9, 59-71.
    • (2005) J. Cell. Mol. Med , vol.9 , pp. 59-71
    • Song, G.1    Ouyang, G.2    Bao, S.3
  • 37
    • 56149111920 scopus 로고    scopus 로고
    • Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression
    • Tang, J., Yang, X., and Liu, X. (2008). Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression. Oncogene 27, 6635-6645.
    • (2008) Oncogene , vol.27 , pp. 6635-6645
    • Tang, J.1    Yang, X.2    Liu, X.3
  • 39
    • 77953811831 scopus 로고    scopus 로고
    • PKB/AKT phosphorylation of the transcription factor Twist-1 at Ser42 inhibits p53 activity in response to DNA damage
    • Vichalkovski, A., Gresko, E., Hess, D., Restuccia, D.F., and Hemmings, B.A. (2010). PKB/AKT phosphorylation of the transcription factor Twist-1 at Ser42 inhibits p53 activity in response to DNA damage. Oncogene 29, 3554-3565.
    • (2010) Oncogene , vol.29 , pp. 3554-3565
    • Vichalkovski, A.1    Gresko, E.2    Hess, D.3    Restuccia, D.F.4    Hemmings, B.A.5
  • 40
    • 0034677550 scopus 로고    scopus 로고
    • The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells
    • Wai, D.H., Knezevich, S.R., Lucas, T., Jansen, B., Kay, R.J., and Sorensen, P.H. (2000). The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells. Oncogene 19, 906-915.
    • (2000) Oncogene , vol.19 , pp. 906-915
    • Wai, D.H.1    Knezevich, S.R.2    Lucas, T.3    Jansen, B.4    Kay, R.J.5    Sorensen, P.H.6
  • 41
    • 84865830634 scopus 로고    scopus 로고
    • Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-beta signaling axes
    • Xue, G., Restuccia, D.F., Lan, Q., Hynx, D., Dirnhofer, S., Hess, D., Ruegg, C., and Hemmings, B.A. (2012). Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-beta signaling axes. Cancer Discov. 2, 248-259.
    • (2012) Cancer Discov , vol.2 , pp. 248-259
    • Xue, G.1    Restuccia, D.F.2    Lan, Q.3    Hynx, D.4    Dirnhofer, S.5    Hess, D.6    Ruegg, C.7    Hemmings, B.A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.