TRPM7 promotes the metastatic process in human nasopharyngeal carcinoma

Cancer Letters

Volumn 356, Issue 2, 2015, Pages 483-490

  Chen, Jian Peng ^a   Wang, Jun ^b   Luan, Yi ^c   Wang, Cai Xia ^a   Li, Wen Huan ^a   Zhang, Jin Biao ^d   Sha, Dan ^a   Shen, Rong ^a   Cui, Yan Gang ^a   Zhang, Zheng ^a   Zhang, Li Ming ^a   Wang, Wei Bo ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^c Shandong Center for Disease Control Prevention   (China)

^d Department of Oncology The 148th Hospital Jinan Command of the People's Liberation Army   (China)

Author keywords

Metastasis; Migration; Nasopharyngeal carcinoma; Prognosis; TRPM7

Indexed keywords

SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; MESSENGER RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM7 PROTEIN, HUMAN;

ADULT; ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CANCER SURVIVAL; CELL MIGRATION; CLINICAL FEATURE; CONTROLLED STUDY; DISTANT METASTASIS; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS; METASTASIS INHIBITION; NASOPHARYNX CARCINOMA; OVERALL SURVIVAL; PREDICTION; PROTEIN EXPRESSION; SURVIVAL TIME; TRPM7 GENE; TUMOR INVASION; ANTAGONISTS AND INHIBITORS; CANCER STAGING; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; COMPARATIVE STUDY; ENZYME IMMUNOASSAY; GENETICS; METABOLISM; MIDDLE AGED; NASOPHARYNX; NASOPHARYNX TUMOR; PATHOLOGY; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECONDARY; SURVIVAL RATE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; NASOPHARYNX; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SURVIVAL RATE; TRPM CATION CHANNELS;

EID: 84919459440     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.09.032     Document Type: Article

References (37)

1. Cho W.C. Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol. Cancer 2007, 6:1.
2. Fang W., Li X., Jiang Q., Liu Z., Yang H., Wang S., et al. Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China. J. Transl. Med 2008, 6:32.
3. Yi J.L., Gao L., Huang X.D., Li S.Y., Luo J.W., Cai W.M., et al. Nasopharyngeal carcinoma treated by radical radiotherapy alone: 10-year experience of a single institution. Int. J. Radiat. Oncol. Biol. Phys 2006, 65:161-168.
4. Ma J., Liu L., Tang L., Zong J., Lin A., Lu T., et al. Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma: prognostic value and staging categories. Clin. Cancer Res 2007, 13:1445-1452.
5. Tang L., Mao Y., Liu L., Liang S., Chen Y., Sun Y., et al. The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma: analysis of the spread patterns in lymph nodes by magnetic resonance imaging. Cancer 2009, 115:680-688.
6. Sham J.S., Choy D., Wei W.I. Nasopharyngeal carcinoma: orderly neck node spread. Int. J. Radiat. Oncol. Biol. Phys 1990, 19:929-933.
7. Ma B.B., Chan A.T. Systemic treatment strategies and therapeutic monitoring for advanced nasopharyngeal carcinoma. Expert Rev. Anticancer Ther 2006, 6:383-394.
8. Clapham D.E. TRP channels as cellular sensors. Nature 2003, 426:517-524.
9. Mareel M., Leroy A. Clinical, cellular, and molecular aspects of cancer. Physiol. Rev 2003, 83:337-376.
10. Steeg P.S. Tumor metastasis: mechanistic insights and clinical challenges. Nat. Med 2006, 12:895-904.
11. Prevarskaya N., Skryma R., Shuba Y. Calcium in tumour metastasis: new roles for known actors. Nat. Rev. Cancer 2011, 11:609-618.
12. Middelbeek J., Kuipers A.J., Henneman L. TRPM7 is required for breast tumor cell metastasis. Cancer Res 2012, 72:4250-4261.
13. Ouadid-Ahidouch H., Dhennin-Duthille I., Gautier M., Sevestre H., Ahidouch A. TRP calcium channel and breast cancer: expression, role and correlation with clinical parameters. Bull. Cancer 2012, 99:655-664.
14. Guilbert A., Gautier M., Dhennin-Duthille I., Rybarczyk P., Sahni J., Sevestre H., et al. Transient receptor potential melastatin 7 is involved in oestrogen receptor-negative metastastic breast cancer cells migration through its kinase domain. Eur. J. Cancer 2013, 49:3694-3707.
15. Rybarczyk P., Gautier M., Hague F., Dhennin-Duthille I., Chatelain D., Kerr-Conte J., et al. Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration. Int. J. Cancer 2012, 131:E851-E861.
16. Gao H., Chen X., Du X., Guan B., Liu Y., Zhang H. EGF enhances the migration of cancer cells by up-regulation of TRPM7. Cell Calcium 2011, 50:559-568.
17. 2+ influx. Cell Calcium 2010, 47:425-432.
18. Cheung S.T., Huang D.P., Hui A.B., Lo K.W., Ko C.W., Tsang Y.S., et al. Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus. Int. J. Cancer 1999, 83:121-126.
19. Tsao S.W., Wang X., Liu Y., Cheung Y.C., Feng H., Zheng Z., et al. Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes. Biochim. Biophys. Acta 2002, 1590:150-158.
20. Song L.B., Yan J., Jian S.W., Zhang L., Li M.Z., Li D., et al. Molecular mechanisms of tumor metastasis in nasopharyngeal carcinoma cell sublines. Ai Zheng 2002, 21:158-162.
21. Hui A.B., Cheung S.T., Fong Y., Lo K.W., Huang D.P. Characterization of a new EBV-associated nasopharyngeal carcinoma cell line. Cancer Gene. Cytogenet 1999, 101:83-88.
22. Glaser R., Zhang H.Y., Yao K.T., Zhu H.C., Wang F.X., Li G.Y., et al. Two epithelial tumor cell lines (HNE-1 and HONE -1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas. Proc. Natl. Acad. Sci. U. S. A. 1989, 86:9524-9528.
23. Sizhong Z., Xiukung G., Yi Z. An epithelial cell line established from poorly differentiated nasopharyngeal carcinoma. Int. J. Cancer 1983, 31:587-590.
24. Hong M.H., Mai H.Q., Min H.Q., Ma J., Zhang E.P., Cui N.A. Comparison of the Chinese 1992 and fifth-edition International Union Against Cancer staging systems for staging nasopharyngeal carcinoma. Cancer 2000, 89:242-247.
25. 2+ homeostasis by TRPM7. Cell 2003, 114:191-200.
26. Duncan L.M., Deeds J., Hunter J., Shao J., Holmgren L.M., Woolf E.A., et al. Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Res 1998, 58:1515-1520.
27. Duncan L.M., Deeds J., Cronin F.E., Donovan M., Sober A.J., Kauffman M., et al. Melastatin expression and prognosis in cutaneous malignant melanoma. J. Clin. Oncol 2001, 19:568-576.
28. Tsavaler L., Shapero M.H., Morkowski S., Laus R. Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Res 2001, 61:3760-3769.
29. Bidaux G., Flourakis M., Thebault S., Zholos A., Beck B., Gkika D., et al. Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function. J. Clin. Invest 2007, 117:1647-1657.
30. 2+ homeostasis: the Mg2+nificent TRPM chanzymes. Curr. Biol 2003, 13:R799-R801.
31. Clark K., Middelbeek J., Morrice N.A., Figdor C.G., Lasonder E., van Leeuwen F.N. Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7. PLoS ONE 2008, 3:e1876.
32. Clark K., Langeslag M., van Leeuwen B., Ran L., Ryazanov A.G., Figdor C.G., et al. TRPM7, a novel regulator of actomyosin contractility and cell adhesion. EMBO J. 2006, 25:90-301.
33. Clark K., Langeslag M., van Leeuwen B., Ran L., Ryazanov A.G., Figdor C.G., et al. TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J. Biol. Chem 2006, 281:11260-11270.
34. Clark K., Middelbeek J., Lasonder E., Dulyaninova N.G., Morrice N.A., Ryazanov A.G., et al. TRPM7 regulates myosin-IIA filament stability and protein localization by heavy chain phosphorylation. J. Mol. Biol 2008, 378:788-801.
35. Aydar E., Yeo S., Djamgoz M., Palmer C. Abnormal expression; localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy. Cancer Cell Int 2009, 9:23.
36. Meng X., Cai C., Wu J., Cai S., Ye C., Chen H., et al. TRPM7 mediates breast cancer cell migration and invasion through the MAPK pathway. Cancer Lett 2013, 333:96-102.
37. Davis F.M., Azimi I., Faville R.A., Peters A.A., Jalink K., Putney J.W., et al. Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent. Oncogene 2014, 33:2307-2316.