-
1
-
-
0028587370
-
Identification of the TCL1 gene involved in T-cell malignancies
-
Virgilio L, Narducci MG, Isobe M, Billips LG, Cooper MD, Croce CM, et al. Identification of the TCL1 gene involved in T-cell malignancies. Proc Natl Acad Sci USA 1994; 91(26):12530-12534.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.26
, pp. 12530-12534
-
-
Virgilio, L.1
Narducci, M.G.2
Isobe, M.3
Billips, L.G.4
Cooper, M.D.5
Croce, C.M.6
-
2
-
-
0035839946
-
The role of TCL1 in human T-cell leukemia
-
Pekarsky Y, Hallas C, Croce CM. The role of TCL1 in human T-cell leukemia. Oncogene 2001; 20(40):5638-56343.
-
(2001)
Oncogene
, vol.20
, Issue.40
, pp. 5638-56343
-
-
Pekarsky, Y.1
Hallas, C.2
Croce, C.M.3
-
3
-
-
0030812918
-
The murine Tcl1 oncogene: Embryonic and lymphoid cell expression
-
Narducci MG, Virgilio L, Engiles jB, Buchberg AM, Billips L, Facchiano A, et al. The murine Tcl1 oncogene: Embryonic and lymphoid cell expression. Oncogene 1997; 15(8):919-926.
-
(1997)
Oncogene
, vol.15
, Issue.8
, pp. 919-926
-
-
Narducci, M.G.1
Virgilio, L.2
Engiles, J.B.3
Buchberg, A.M.4
Billips, L.5
Facchiano, A.6
-
4
-
-
0032584080
-
Deregulated expression of TCL1 causes T cell leukemia in mice
-
Virgilio L, Lazzeri C, Bichi R, Nibu K, Narducci MG, Russo G, et al. Deregulated expression of TCL1 causes T cell leukemia in mice. Proc Natl Acad Sci USA 1998; 95(7): 3885-3889.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.7
, pp. 3885-3889
-
-
Virgilio, L.1
Lazzeri, C.2
Bichi, R.3
Nibu, K.4
Narducci, M.G.5
Russo, G.6
-
5
-
-
0031694094
-
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia
-
Takizawa J, Suzuki R, Kuroda H, Utsunomiya A, Kagami Y, Joh T, et al. Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia. jpn j Cancer Res 1998; 89(7):712-718.
-
(1998)
Jpn J Cancer Res
, vol.89
, Issue.7
, pp. 712-718
-
-
Takizawa, J.1
Suzuki, R.2
Kuroda, H.3
Utsunomiya, A.4
Kagami, Y.5
Joh, T.6
-
6
-
-
0034655156
-
Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues
-
Narducci MG, Pescarmona E, Lazzeri C, Signoretti S, Lavinia AM, Remotti D, et al. Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues. Cancer Res 2000; 60(8):2095-2100.
-
(2000)
Cancer Res
, vol.60
, Issue.8
, pp. 2095-2100
-
-
Narducci, M.G.1
Pescarmona, E.2
Lazzeri, C.3
Signoretti, S.4
Lavinia, A.M.5
Remotti, D.6
-
7
-
-
0037195092
-
Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma
-
Hoyer KK, French SW, Turner DE, Nguyen MT, Renard M, Malone CS, et al. Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma. Proc Natl Acad Sci USA 2002; 99(22):14392-14397.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.22
, pp. 14392-14397
-
-
Hoyer, K.K.1
French, S.W.2
Turner, D.E.3
Nguyen, M.T.4
Renard, M.5
Malone, C.S.6
-
8
-
-
0037076279
-
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
-
Bichi R, Shinton SA, Martin ES, Koval A, Calin GA, Cesari R, et al. Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression. Proc Natl Acad Sci USA 2002; 99(10):6955-6960.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.10
, pp. 6955-6960
-
-
Bichi, R.1
Shinton, S.A.2
Martin, E.S.3
Koval, A.4
Calin, G.A.5
Cesari, R.6
-
9
-
-
84863529042
-
Novel insights in molecular mechanisms of CLL
-
Zanesi N, Balatti V, Bottoni A, Croce CM, Pekarsky Y. Novel insights in molecular mechanisms of CLL. Curr Pharm Des 2012; 18(23):3363-3372.
-
(2012)
Curr Pharm Des
, vol.18
, Issue.23
, pp. 3363-3372
-
-
Zanesi, N.1
Balatti, V.2
Bottoni, A.3
Croce, C.M.4
Pekarsky, Y.5
-
11
-
-
84905970939
-
Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy
-
Simonetti G, Bertilaccio MT, Ghia P, Klein U. Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy. Blood 2014; 124(7):1010-1019.
-
(2014)
Blood
, vol.124
, Issue.7
, pp. 1010-1019
-
-
Simonetti, G.1
Bertilaccio, M.T.2
Ghia, P.3
Klein, U.4
-
12
-
-
31544471656
-
Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhe-matopoietic malignancies in Emu-TCL1 transgenic mice
-
Zanesi N, Aqeilan R, Drusco A, Kaou M, Sevignani C, Costinean S, et al. Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhe-matopoietic malignancies in Emu-TCL1 transgenic mice. Cancer Res 2006; 66(2):915-920.
-
(2006)
Cancer Res
, vol.66
, Issue.2
, pp. 915-920
-
-
Zanesi, N.1
Aqeilan, R.2
Drusco, A.3
Kaou, M.4
Sevignani, C.5
Costinean, S.6
-
13
-
-
0034724199
-
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation
-
Pekarsky Y, Koval A, Hallas C, Bichi R, Tresini M, Malstrom S, et al. Tcl1 enhances Akt kinase activity and mediates its nuclear translocation. Proc Natl Acad Sci USA 2000; 97(7):3028-3033.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.7
, pp. 3028-3033
-
-
Pekarsky, Y.1
Koval, A.2
Hallas, C.3
Bichi, R.4
Tresini, M.5
Malstrom, S.6
-
14
-
-
0033636528
-
The protooncogene TCL1 is an Akt kinase coactivator
-
Laine J, Kunstle G, Obata T, Sha M, Noguchi M. The protooncogene TCL1 is an Akt kinase coactivator. Mol Cell 2000; 6(2):395-407.
-
(2000)
Mol Cell
, vol.6
, Issue.2
, pp. 395-407
-
-
Laine, J.1
Kunstle, G.2
Obata, T.3
Sha, M.4
Noguchi, M.5
-
15
-
-
33747181341
-
Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia
-
Johnson AJ, Lucas DM, Muthusamy N, Smith LL, Edwards RB, De Lay MD, et al. Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia. Blood 2006; 108(4):1334-1338.
-
(2006)
Blood
, vol.108
, Issue.4
, pp. 1334-1338
-
-
Johnson, A.J.1
Lucas, D.M.2
Muthusamy, N.3
Smith, L.L.4
Edwards, R.B.5
De Lay, M.D.6
-
16
-
-
33746817989
-
B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia
-
Yan XJ, Albesiano E, Zanesi N, Yancopoulos S, Sawyer A, Romano E, et al. B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2006; 103(31):11713-11718.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.31
, pp. 11713-11718
-
-
Yan, X.J.1
Albesiano, E.2
Zanesi, N.3
Yancopoulos, S.4
Sawyer, A.5
Romano, E.6
-
17
-
-
33846883742
-
B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CbetaII
-
Abrams ST, Lakum T, Lin K, jones GM, Treweeke AT, Farahani M, et al. B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CbetaII. Blood 2007; 109(3):1193-1201.
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 1193-1201
-
-
Abrams, S.T.1
Lakum, T.2
Lin, K.3
Jones, G.M.4
Treweeke, A.T.5
Farahani, M.6
-
18
-
-
63849093256
-
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: Validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia
-
Holler C, Pinon jD, Denk U, Heyder C, Hofbauer S, Greil R, et al. PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: Validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia. Blood 2009; 113(12):2791-2794.
-
(2009)
Blood
, vol.113
, Issue.12
, pp. 2791-2794
-
-
Holler, C.1
Pinon, J.D.2
Denk, U.3
Heyder, C.4
Hofbauer, S.5
Greil, R.6
-
19
-
-
64049104989
-
Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia
-
Wu QL, Zierold C, Ranheim EA. Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia. Blood 2009; 113(13):3031-3039.
-
(2009)
Blood
, vol.113
, Issue.13
, pp. 3031-3039
-
-
Wu, Q.L.1
Zierold, C.2
Ranheim, E.A.3
-
21
-
-
0033711624
-
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
-
Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, et al. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 2000; 13(1):15-24.
-
(2000)
Immunity
, vol.13
, Issue.1
, pp. 15-24
-
-
Reya, T.1
O'Riordan, M.2
Okamura, R.3
Devaney, E.4
Willert, K.5
Nusse, R.6
-
22
-
-
62149149441
-
The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo
-
Lucas DM, Edwards RB, Lozanski G, West DA, Shin jD, Vargo MA, et al. The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo. Blood 2009; 113(19):4656-4666.
-
(2009)
Blood
, vol.113
, Issue.19
, pp. 4656-4666
-
-
Lucas, D.M.1
Edwards, R.B.2
Lozanski, G.3
West, D.A.4
Shin, J.D.5
Vargo, M.A.6
-
23
-
-
0025775062
-
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
-
Monks A, Scudiero D, Skehan P, Shoemaker R, Paull K, Vistica D, et al. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. j Natl Cancer Inst 1991; 83(11):757-766.
-
(1991)
J Natl Cancer Inst
, vol.83
, Issue.11
, pp. 757-766
-
-
Monks, A.1
Scudiero, D.2
Skehan, P.3
Shoemaker, R.4
Paull, K.5
Vistica, D.6
-
24
-
-
65549151712
-
E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction
-
Gorgun G, Ramsay AG, Holderried TA, Zahrieh D, Le Dieu R, Liu F, et al. E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction. Proc Natl Acad Sci USA 2009; 106(15):6250-6255.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.15
, pp. 6250-6255
-
-
Gorgun, G.1
Ramsay, A.G.2
Holderried, T.A.3
Zahrieh, D.4
Le Dieu, R.5
Liu, F.6
-
25
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128(4):683-692.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
26
-
-
69449100327
-
Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia
-
Chen SS, Raval A, Johnson AJ, Hertlein E, Liu TH, Jin VX, et al. Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2009; 106(32):13433-13438.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.32
, pp. 13433-13438
-
-
Chen, S.S.1
Raval, A.2
Johnson, A.J.3
Hertlein, E.4
Liu, T.H.5
Jin, V.X.6
-
27
-
-
20044372326
-
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells
-
Messmer BT, Messmer D, Allen SL, Kolitz JE, Kudalkar P, Cesar D, et al. In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest 2005; 115(3):755-764.
-
(2005)
J Clin Invest
, vol.115
, Issue.3
, pp. 755-764
-
-
Messmer, B.T.1
Messmer, D.2
Allen, S.L.3
Kolitz, J.E.4
Kudalkar, P.5
Cesar, D.6
-
28
-
-
73349098730
-
Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression
-
Enzler T, Kater AP, Zhang W, Widhopf GF, 2nd, Chuang HY, Lee J, et al. Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression. Blood 2009; 114(20):4469-4476.
-
(2009)
Blood
, vol.114
, Issue.20
, pp. 4469-4476
-
-
Enzler, T.1
Kater, A.P.2
Zhang, W.3
Widhopf, G.F.4
Chuang, H.Y.5
Lee, J.6
-
29
-
-
33750121336
-
RhoHGTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development
-
Gu Y, Chae HD, Siefring jE, jasti AC, Hildeman DA, Williams DA. RhoHGTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development. Nat Immunol 2006; 7(11):1182-1190.
-
(2006)
Nat Immunol
, vol.7
, Issue.11
, pp. 1182-1190
-
-
Gu, Y.1
Chae, H.D.2
Siefring, J.E.3
Jasti, A.C.4
Hildeman, D.A.5
Williams, D.A.6
-
30
-
-
74249108856
-
Involvement of RhoHGTPase in the development of B-cell chronic lymphocytic leukemia
-
Sanchez-Aguilera A, Rattmann I, Drew DZ, Muller LU, Summey V, Lucas DM, et al. Involvement of RhoHGTPase in the development of B-cell chronic lymphocytic leukemia. Leukemia 2010; 24(1):97-104.
-
(2010)
Leukemia
, vol.24
, Issue.1
, pp. 97-104
-
-
Sanchez-Aguilera, A.1
Rattmann, I.2
Drew, D.Z.3
Muller, L.U.4
Summey, V.5
Lucas, D.M.6
-
31
-
-
78149309123
-
HS1 has a central role in the trafficking and homing of leukemic B cells
-
Scielzo C, Bertilaccio MT, Simonetti G, Dagklis A, ten Hacken E, Fazi C, et al. HS1 has a central role in the trafficking and homing of leukemic B cells. Blood 2010; 116(18):3537-3546.
-
(2010)
Blood
, vol.116
, Issue.18
, pp. 3537-3546
-
-
Scielzo, C.1
Bertilaccio, M.T.2
Simonetti, G.3
Dagklis, A.4
Ten Hacken, E.5
Fazi, C.6
-
32
-
-
84891849709
-
Loss of p53 and altered miR15-a/16-1short right arrowMCL-1 pathway in CLL: Insights from TCL1-Tg:P53(-/-) mouse model and primary human leukemia cells
-
Liu J, Chen G, Feng L, Zhang W, Pelicano H, Wang F, et al. Loss of p53 and altered miR15-a/16-1short right arrowMCL-1 pathway in CLL: Insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells. Leukemia 2014; 28(1):118-128.
-
(2014)
Leukemia
, vol.28
, Issue.1
, pp. 118-128
-
-
Liu, J.1
Chen, G.2
Feng, L.3
Zhang, W.4
Pelicano, H.5
Wang, F.6
-
33
-
-
78751682784
-
Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL
-
Chen SS, Claus R, Lucas DM, Yu L, Qian J, Ruppert AS, et al. Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL. Blood 2011; 117(3):862-871.
-
(2011)
Blood
, vol.117
, Issue.3
, pp. 862-871
-
-
Chen, S.S.1
Claus, R.2
Lucas, D.M.3
Yu, L.4
Qian, J.5
Ruppert, A.S.6
-
34
-
-
79960691639
-
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models
-
Bertilaccio MT, Simonetti G, Dagklis A, Rocchi M, Rodriguez TV, Apollonio B, et al. Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models. Blood 2011; 118(3):660-669.
-
(2011)
Blood
, vol.118
, Issue.3
, pp. 660-669
-
-
Bertilaccio, M.T.1
Simonetti, G.2
Dagklis, A.3
Rocchi, M.4
Rodriguez, T.V.5
Apollonio, B.6
-
35
-
-
84880474898
-
Accelerated progression of chronic lymphocytic leukemia in Emu-TCL1 mice expressing catalytically inactive RAG1
-
S1-16
-
Nganga VK, Palmer VL, Naushad H, Kassmeier MD, Anderson DK, Perry GA, et al. Accelerated progression of chronic lymphocytic leukemia in Emu-TCL1 mice expressing catalytically inactive RAG1. Blood 2013; 121(19):3855-3866, S1-16.
-
(2013)
Blood
, vol.121
, Issue.19
, pp. 3855-3866
-
-
Nganga, V.K.1
Palmer, V.L.2
Naushad, H.3
Kassmeier, M.D.4
Anderson, D.K.5
Perry, G.A.6
-
36
-
-
84893502005
-
Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model
-
Lascano V, Guadagnoli M, Schot jG, Luijks DM, Guikema jE, Cameron K, et al. Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model. Blood 2013; 122(24):3960-3963.
-
(2013)
Blood
, vol.122
, Issue.24
, pp. 3960-3963
-
-
Lascano, V.1
Guadagnoli, M.2
Schot, J.G.3
Luijks, D.M.4
Guikema, J.E.5
Cameron, K.6
-
37
-
-
84892611828
-
ROR1 can interact with TCL1 and enhance leukemogenesis in Emu-TCL1 transgenic mice
-
Widhopf GF, 2nd, Cui B, Ghia EM, Chen L, Messer K, Shen Z, et al. ROR1 can interact with TCL1 and enhance leukemogenesis in Emu-TCL1 transgenic mice. Proc Natl Acad Sci USA 2014; 111(2):793-798.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.2
, pp. 793-798
-
-
Widhopf, G.F.1
Cui, B.2
Ghia, E.M.3
Chen, L.4
Messer, K.5
Shen, Z.6
-
38
-
-
84873542962
-
Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor
-
Reinart N, Nguyen PH, Boucas J, Rosen N, Kvasnicka HM, Heukamp L, et al. Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor. Blood 2013; 121(5):812-821.
-
(2013)
Blood
, vol.121
, Issue.5
, pp. 812-821
-
-
Reinart, N.1
Nguyen, P.H.2
Boucas, J.3
Rosen, N.4
Kvasnicka, H.M.5
Heukamp, L.6
-
39
-
-
84881015517
-
CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia
-
Fedorchenko O, Stiefelhagen M, Peer-Zada AA, Barthel R, Mayer P, Eckei L, et al. CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. Blood 2013; 121(20):4126-4136.
-
(2013)
Blood
, vol.121
, Issue.20
, pp. 4126-4136
-
-
Fedorchenko, O.1
Stiefelhagen, M.2
Peer-Zada, A.A.3
Barthel, R.4
Mayer, P.5
Eckei, L.6
-
40
-
-
84880420282
-
A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model
-
Zanesi N, Balatti V, Riordan J, Burch A, Rizzotto L, Palamarchuk A, et al. A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model. Blood 2013; 121(21):4355-4358.
-
(2013)
Blood
, vol.121
, Issue.21
, pp. 4355-4358
-
-
Zanesi, N.1
Balatti, V.2
Riordan, J.3
Burch, A.4
Rizzotto, L.5
Palamarchuk, A.6
-
41
-
-
22444431606
-
Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system
-
Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature 2005; 436(7048):221-226.
-
(2005)
Nature
, vol.436
, Issue.7048
, pp. 221-226
-
-
Dupuy, A.J.1
Akagi, K.2
Largaespada, D.A.3
Copeland, N.G.4
Jenkins, N.A.5
-
42
-
-
77952424509
-
CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation
-
Efanov A, Zanesi N, Nazaryan N, Santanam U, Palamarchuk A, Croce CM, et al. CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation. Leukemia 2010; 24(5):970-975.
-
(2010)
Leukemia
, vol.24
, Issue.5
, pp. 970-975
-
-
Efanov, A.1
Zanesi, N.2
Nazaryan, N.3
Santanam, U.4
Palamarchuk, A.5
Croce, C.M.6
-
43
-
-
84863138658
-
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)
-
Palamarchuk A, Yan PS, Zanesi N, Wang L, Rodrigues B, Murphy M, et al. Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL). Proc Natl Acad Sci USA 2012; 109(7):2555-2560.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.7
, pp. 2555-2560
-
-
Palamarchuk, A.1
Yan, P.S.2
Zanesi, N.3
Wang, L.4
Rodrigues, B.5
Murphy, M.6
-
44
-
-
84873567628
-
Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function
-
DiLillo DJ, Weinberg JB, Yoshizaki A, Horikawa M, Bryant JM, Iwata Y, et al. Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function. Leukemia 2013; 27(1):170-182.
-
(2013)
Leukemia
, vol.27
, Issue.1
, pp. 170-182
-
-
DiLillo, D.J.1
Weinberg, J.B.2
Yoshizaki, A.3
Horikawa, M.4
Bryant, J.M.5
Iwata, Y.6
-
45
-
-
80052482371
-
Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL
-
Hofbauer JP, Heyder C, Denk U, Kocher T, Holler C, Trapin D, et al. Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL. Leukemia 2011; 25(9):1452-1458.
-
(2011)
Leukemia
, vol.25
, Issue.9
, pp. 1452-1458
-
-
Hofbauer, J.P.1
Heyder, C.2
Denk, U.3
Kocher, T.4
Holler, C.5
Trapin, D.6
-
46
-
-
83055186737
-
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia
-
Motiwala T, Zanesi N, Datta J, Roy S, Kutay H, Checovich AM, et al. AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. Blood 2011; 118(23):6132-6140.
-
(2011)
Blood
, vol.118
, Issue.23
, pp. 6132-6140
-
-
Motiwala, T.1
Zanesi, N.2
Datta, J.3
Roy, S.4
Kutay, H.5
Checovich, A.M.6
-
47
-
-
84864542591
-
Overexpression of TCL1 activates the endoplasmic reticulum stress response: A novel mechanism of leukemic progression in mice
-
Kriss CL, Pinilla-Ibarz JA, Mailloux AW, Powers JJ, Tang CH, Kang CW, et al. Overexpression of TCL1 activates the endoplasmic reticulum stress response: A novel mechanism of leukemic progression in mice. Blood 2012; 120(5):1027-1038.
-
(2012)
Blood
, vol.120
, Issue.5
, pp. 1027-1038
-
-
Kriss, C.L.1
Pinilla-Ibarz, J.A.2
Mailloux, A.W.3
Powers, J.J.4
Tang, C.H.5
Kang, C.W.6
-
48
-
-
84904326052
-
Chronic lymphocytic leukemia cells in a lymph node microenvironment depict molecular signature associated with an aggressive disease
-
Mittal AK, Chaturvedi NK, Rai KJ, Gilling-Cutucache CE, Nordgren TM, Moragues M, et al. Chronic lymphocytic leukemia cells in a lymph node microenvironment depict molecular signature associated with an aggressive disease. Mol Med 2014; 20(1):290-301.
-
(2014)
Mol Med
, vol.20
, Issue.1
, pp. 290-301
-
-
Mittal, A.K.1
Chaturvedi, N.K.2
Rai, K.J.3
Gilling-Cutucache, C.E.4
Nordgren, T.M.5
Moragues, M.6
-
49
-
-
84915745531
-
Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation
-
Heinig K, Gatjen M, Grau M, Stache V, Anagnostopoulos I, Gerlach K, et al. Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation. Cancer Discov 2014.
-
(2014)
Cancer Discov
-
-
Heinig, K.1
Gatjen, M.2
Grau, M.3
Stache, V.4
Anagnostopoulos, I.5
Gerlach, K.6
-
50
-
-
78649759107
-
The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Emu-TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling
-
Suljagic M, Longo PG, Bennardo S, Perlas E, Leone G, Laurenti L, et al. The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Emu-TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling. Blood 2010; 116(23):4894-4905.
-
(2010)
Blood
, vol.116
, Issue.23
, pp. 4894-4905
-
-
Suljagic, M.1
Longo, P.G.2
Bennardo, S.3
Perlas, E.4
Leone, G.5
Laurenti, L.6
-
51
-
-
84871213835
-
Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia
-
Merkel O, Wacht N, Sifft E, Melchardt T, Hamacher F, Kocher T, et al. Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia. Leukemia 2012; 26(12):2508-2516.
-
(2012)
Leukemia
, vol.26
, Issue.12
, pp. 2508-2516
-
-
Merkel, O.1
Wacht, N.2
Sifft, E.3
Melchardt, T.4
Hamacher, F.5
Kocher, T.6
-
52
-
-
84897901864
-
Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL)
-
Woyach JA, Bojnik E, Ruppert AS, Stefanovski MR, Goettl VM, Smucker KA, et al. Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL). Blood 2014; 123(8): 1207-1213.
-
(2014)
Blood
, vol.123
, Issue.8
, pp. 1207-1213
-
-
Woyach, J.A.1
Bojnik, E.2
Ruppert, A.S.3
Stefanovski, M.R.4
Goettl, V.M.5
Smucker, K.A.6
-
53
-
-
84928405738
-
OSU-T315: A novel targeted therapeutic that antagonizes AKT membrane localization and activation of chronic lymphocytic leukemia cells
-
Liu TM, Ling Y, Woyach jA, Beckwith K, Yeh YY, Hertlein E, et al. OSU-T315: A novel targeted therapeutic that antagonizes AKT membrane localization and activation of chronic lymphocytic leukemia cells. Blood 2014.
-
(2014)
Blood
-
-
Liu, T.M.1
Ling, Y.2
Woyach, J.A.3
Beckwith, K.4
Yeh, Y.Y.5
Hertlein, E.6
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