-
1
-
-
0027367546
-
Aminoacid polymorphisms of insulin receptor substrate-1 in non-inslin-dependent diabetes mellitus
-
DOI 10.1016/0140-6736(93)92694-O
-
Almind K, Bjorbaek C, Vestergaard H, et al. (1993) Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulindependent diabetes mellitus. Lancet 342:828-832. (Pubitemid 23285910)
-
(1993)
Lancet
, vol.342
, Issue.8875
, pp. 828-832
-
-
Almind, K.1
Bjorbaek, C.2
Vestergaard, H.3
Hansen, T.4
Echwald, S.5
Pedersen, O.6
-
2
-
-
0029893417
-
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies
-
Almind K, Inoue G, Pedersen O, et al. (1996) A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies. J Clin Invest 97:2569-2575.
-
(1996)
J Clin Invest
, vol.97
, pp. 2569-2575
-
-
Almind, K.1
Inoue, G.2
Pedersen, O.3
-
3
-
-
1842334456
-
Report of the Expert Committee on the diagnosis and classification of diabetes mellitus
-
American Diabetes Association
-
American Diabetes Association (1997) Report of the Expert Committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 20:1183-1197.
-
(1997)
Diabetes Care
, vol.20
, pp. 1183-1197
-
-
-
4
-
-
77949874508
-
Protein tyrosine phosphatase-1B (PTP-1B) knockdown improves palmitate-induced insulin resistance in C2C12 skeletal muscle cells
-
Bakhtiyari S, Meshkani R, Taghikhani M, et al. (2010) Protein tyrosine phosphatase-1B (PTP-1B) knockdown improves palmitate-induced insulin resistance in C2C12 skeletal muscle cells. Lipids 45:237-244.
-
(2010)
Lipids
, vol.45
, pp. 237-244
-
-
Bakhtiyari, S.1
Meshkani, R.2
Taghikhani, M.3
-
5
-
-
0033048456
-
Exclusion of insulin receptor substrate 2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes
-
Bektas A, Warram JH, White MF, et al. (1999) Exclusion of insulin receptor substrate 2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes. Diabetes 48:640-642. (Pubitemid 29106882)
-
(1999)
Diabetes
, vol.48
, Issue.3
, pp. 640-642
-
-
Bektas, A.1
Warram, J.H.2
White, M.F.3
Krolewski, A.S.4
Doria, A.5
-
6
-
-
33845772965
-
The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians
-
DOI 10.1038/sj.ijo.0803356, PII 0803356
-
Bodhini D, Radha V, Deepa R, et al. (2007) The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians. Int J Obes (Lond) 31:97-102. (Pubitemid 46006021)
-
(2007)
International Journal of Obesity
, vol.31
, Issue.1
, pp. 97-102
-
-
Bodhini, D.1
Radha, V.2
Deepa, R.3
Ghosh, S.4
Majumder, P.P.5
Rao, M.R.S.6
Mohan, V.7
-
7
-
-
72049107717
-
Association of Gly972Arg polymorphism of IRS1 gene with type 2 diabetes mellitus in lean participants of a national health survey in Mexico: A candidate gene study
-
Burguete-Garcia AI, Cruz-Lopez M, Madrid-Marina V, et al. (2010) Association of Gly972Arg polymorphism of IRS1 gene with type 2 diabetes mellitus in lean participants of a national health survey in Mexico: a candidate gene study. Metabolism 59:38-45.
-
(2010)
Metabolism
, vol.59
, pp. 38-45
-
-
Burguete-Garcia, A.I.1
Cruz-Lopez, M.2
Madrid-Marina, V.3
-
8
-
-
0037238412
-
Polymorphisms of the insulin receptor subtrate-2 in patients with type 2 diabetes
-
DOI 10.1210/jc.2002-020807
-
D'Alfonso R, Marini MA, Frittitta L, et al. (2003) Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes. J Clin Endocrinol Metab 88:317-322. (Pubitemid 36115183)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.1
, pp. 317-322
-
-
D'Alfonso, R.1
Marini, M.A.2
Frittitta, L.3
Sorge, R.4
Frontoni, S.5
Porzio, O.6
Mariani, L.M.7
Lauro, D.8
Gambardella, S.9
Trischitta, V.10
Federici, M.11
Lauro, R.12
Sesti, G.13
-
9
-
-
0035461406
-
Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women with Polycystic Ovary Syndrome
-
El Mkadem SA, Lautier C, Macari F, et al. (2001) Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome. Diabetes 50:2164-2168. (Pubitemid 33643687)
-
(2001)
Diabetes
, vol.50
, Issue.9
, pp. 2164-2168
-
-
El Mkadem, S.A.1
Lautier, C.2
Macari, F.3
Molinari, N.4
Lefebvre, P.5
Renard, E.6
Gris, J.C.7
Cros, G.8
Daures, J.P.9
Bringer, J.10
White, M.F.11
Grigorescu, F.12
-
10
-
-
9444289880
-
Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes
-
DOI 10.2337/diabetes.53.12.3313
-
Florez JC, Sjogren M, Burtt N, et al. (2004) Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes. Diabetes 53:3313-3318. (Pubitemid 39564509)
-
(2004)
Diabetes
, vol.53
, Issue.12
, pp. 3313-3318
-
-
Florez, J.C.1
Sjogren, M.2
Burtt, N.3
Orho-Melander, M.4
Schayer, S.5
Sun, M.6
Almgren, P.7
Lindblad, U.8
Tuomi, T.9
Gaudet, D.10
Hudson, T.J.11
Daly, M.J.12
Ardlie, K.G.13
Hirschhorn, J.N.14
Altshuler, D.15
Groop, L.16
-
11
-
-
0037026739
-
Insulin resistance as the core defect in type 2 diabetes mellitus
-
PII S0002914902025535
-
Goldstein BJ (2002) Insulin resistance as the core defect in type 2 diabetes mellitus. Am J Cardiol 90:3G-10G. (Pubitemid 35266675)
-
(2002)
American Journal of Cardiology
, vol.90
, Issue.5 SUPPL.
-
-
Goldstein, B.J.1
-
12
-
-
0027422281
-
Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families [21]
-
Hager J, Zouali H, Velho G, et al. (1993) Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families. Lancet 342:1430. (Pubitemid 23361267)
-
(1993)
Lancet
, vol.342
, Issue.8884
, pp. 1430
-
-
Hager, J.1
Zouali, H.2
Velho, G.3
Froguel, P.4
-
13
-
-
0026969347
-
Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM)
-
Hamman RF (1992) Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM). Diabetes Metab Rev 8:287-338. (Pubitemid 23171181)
-
(1992)
Diabetes/Metabolism Reviews
, vol.8
, Issue.4
, pp. 287-338
-
-
Hamman, R.F.1
-
14
-
-
0034351407
-
972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells
-
DOI 10.1210/jc.85.5.2004
-
Hribal ML, Federici M, Porzio O, et al. (2000) The Gly/Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells. J Clin Endocrinol Metab 85:2004-2013. (Pubitemid 32269313)
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, Issue.5
, pp. 2004-2013
-
-
Hribal, M.L.1
Federici, M.2
Porzio, O.3
Lauro, D.4
Borboni, P.5
Accili, D.6
Lauro, R.7
Sesti, G.8
-
15
-
-
0033497683
-
Insulin sensitivity is not affected by mutation of codon 972 of the human IRS-1 gene
-
Ito K, Katsuki A, Furuta M, et al. (1999) Insulin sensitivity is not affected by mutation of codon 972 of the human IRS-1 gene. Horm Res 52:230-234. (Pubitemid 30303715)
-
(1999)
Hormone Research
, vol.52
, Issue.5
, pp. 230-234
-
-
Ito, K.1
Katsuki, A.2
Furuta, M.3
Fujii, M.4
Tsuchihashi, K.5
Hori, Y.6
Yano, Y.7
Sumida, Y.8
Adachi, Y.9
-
16
-
-
0042572474
-
Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: A meta-analysis of 27 studies
-
DOI 10.1007/s00125-003-1126-4
-
Jellema A, Zeegers MP, Feskens EJ, et al. (2003) Gly972Arg variant in the insulin receptor substrate-1 gene and association with type 2 diabetes: a meta-analysis of 27 studies. Diabetologia 46:990-995. (Pubitemid 36961324)
-
(2003)
Diabetologia
, vol.46
, Issue.7
, pp. 990-995
-
-
Jellema, A.1
Zeegers, M.P.A.2
Feskens, E.J.M.3
Dagnelie, P.C.4
Mensink, R.P.5
-
17
-
-
0031739242
-
Mapping of the human insulin receptor substrate-2 gene, identification of a linked polymorphic marker and linkage analysis in families with Type II diabetes: No evidence for a major susceptibility role
-
DOI 10.1007/s001250051081
-
Kalidas K, Wasson J, Glaser B, et al. (1998) Mapping of the human insulin receptor substrate-2 gene, identification of a linked polymorphic marker and linkage analysis in families with type II diabetes: no evidence for a major susceptibility role. Diabetologia 41:1389-1391. (Pubitemid 28488769)
-
(1998)
Diabetologia
, vol.41
, Issue.11
, pp. 1389-1391
-
-
Kalidas, K.1
Wasson, J.2
Glaser, B.3
Meyer, J.M.4
Duprat, L.J.5
White, M.F.6
Permutt, M.A.7
-
18
-
-
0034641849
-
Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes
-
Mammarella S, Romano F, Di Valerio A, et al. (2000) Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes. Hum Mol Genet 9:2517-2521.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2517-2521
-
-
Mammarella, S.1
Romano, F.2
Di Valerio, A.3
-
19
-
-
0037622751
-
972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients
-
DOI 10.1210/jc.2002-021716
-
Marini MA, Frontoni S, Mineo D, et al. (2003) The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients. J Clin Endocrinol Metab 88:3368-3371. (Pubitemid 36877518)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.7
, pp. 3368-3371
-
-
Marini, M.A.1
Frontoni, S.2
Mineo, D.3
Bracaglia, D.4
Cardellini, M.5
De Nicolais, P.6
Baroni, A.7
D'Alfonso, R.8
Perna, M.9
Lauro, D.10
Federici, M.11
Gambardella, S.12
Lauro, R.13
Sesti, G.14
-
20
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
-
DOI 10.1007/BF00280883
-
Matthews DR, Hosker JP, Rudenski AS, et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419. (Pubitemid 15018832)
-
(1985)
Diabetologia
, vol.28
, Issue.7
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
-
21
-
-
0035557623
-
Molecular diagnostics in monogenic and multifactorial forms of Type 2 diabetes
-
McCarthy MI, Hattersley AT (2001) Molecular diagnostics in monogenic and multifactorial forms of type 2 diabetes. Expert Rev Mol Diagn 1:403-412. (Pubitemid 34654420)
-
(2001)
Expert Review of Molecular Diagnostics
, vol.1
, Issue.4
, pp. 403-412
-
-
McCarthy, M.I.1
Hattersley, A.T.2
-
22
-
-
20144387580
-
The haplotypes of the IRS-2 gene affect insulin sensitivity in Japanese patients with type 2 diabetes
-
DOI 10.1016/j.diabres.2004.08.009
-
Okazawa K, Yoshimasa Y, Miyamoto Y, et al. (2005) The haplotypes of the IRS-2 gene affect insulin sensitivity in Japanese patients with type 2 diabetes. Diabetes Res Clin Pract 68: 39-48. (Pubitemid 40461885)
-
(2005)
Diabetes Research and Clinical Practice
, vol.68
, Issue.1
, pp. 39-48
-
-
Okazawa, K.1
Yoshimasa, Y.2
Miyamoto, Y.3
Takahashi-Yasuno, A.4
Miyawaki, T.5
Masuzaki, H.6
Hayashi, T.7
Hosoda, K.8
Inoue, G.9
Nakao, K.10
-
23
-
-
67349234567
-
The G1057D polymorphism of IRS-2 gene is not associated with type 2 diabetes and obese patients among ethnic groups in Tunisian population
-
Ouederni TB, Sanchez-Corona J, Flores Martinez SE, et al. (2009) The G1057D polymorphism of IRS-2 gene is not associated with type 2 diabetes and obese patients among ethnic groups in Tunisian population. Clin Biochem 42:1169-1173.
-
(2009)
Clin Biochem
, vol.42
, pp. 1169-1173
-
-
Ouederni, T.B.1
Sanchez-Corona, J.2
Flores Martinez, S.E.3
-
24
-
-
0032587076
-
The Gly972/Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells
-
Porzio O, Federici M, Hribal ML, et al. (1999) The Gly972/Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells. J Clin Invest 104:357-364.
-
(1999)
J Clin Invest
, vol.104
, pp. 357-364
-
-
Porzio, O.1
Federici, M.2
Hribal, M.L.3
-
25
-
-
0034736343
-
Interaction of the G protein beta 3 subunit T825 allele and the IRS-1 Arg972 variant in type 2 diabetes
-
Rosskopf D, Frey U, Eckhardt S, et al. (2000) Interaction of the G protein beta 3 subunit T825 allele and the IRS-1 Arg972 variant in type 2 diabetes. Eur J Med Res 5:484-490.
-
(2000)
Eur J Med Res
, vol.5
, pp. 484-490
-
-
Rosskopf, D.1
Frey, U.2
Eckhardt, S.3
-
26
-
-
79953728436
-
The ENPP1 K121Q polymorphism is not associated with type 2 diabetes and related metabolic traits in an Iranian population
-
Saberi H, Mohammadtaghvaei N, Gulkho S, et al. (2011) The ENPP1 K121Q polymorphism is not associated with type 2 diabetes and related metabolic traits in an Iranian population. Mol Cell Biochem 350:113-118.
-
(2011)
Mol Cell Biochem
, vol.350
, pp. 113-118
-
-
Saberi, H.1
Mohammadtaghvaei, N.2
Gulkho, S.3
-
27
-
-
0034810894
-
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
-
DOI 10.1096/fj.01-0009rev
-
Sesti G, Federici M, Hribal ML, et al. (2001) Defects of the insulin receptor substrate (IRS) system in human metabolic disorders. Faseb J 15:2099-2111. (Pubitemid 32927927)
-
(2001)
FASEB Journal
, vol.15
, Issue.12
, pp. 2099-2111
-
-
Sesti, G.1
Federici, M.2
Hribal, M.L.3
Lauro, D.4
Sbraccia, P.5
Lauro, R.6
-
28
-
-
0037982811
-
Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity
-
DOI 10.2337/diabetes.52.6.1544
-
Stefan N, Kovacs P, Stumvoll M, et al. (2003) Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity. Diabetes 52:1544-1550. (Pubitemid 36666212)
-
(2003)
Diabetes
, vol.52
, Issue.6
, pp. 1544-1550
-
-
Stefan, N.1
Kovacs, P.2
Stumvoll, M.3
Hanson, R.L.4
Lehn-Stefan, A.5
Permana, P.A.6
Baier, L.J.7
Tataranni, P.A.8
Silver, K.9
Bogardus, C.10
-
29
-
-
0347756677
-
Genetics and functional genomics of type 2 diabetes mellitus
-
Toye A, Gauguier D (2003) Genetics and functional genomics of type 2 diabetes mellitus. Genome Biol 4:241.
-
(2003)
Genome Biol
, vol.4
, pp. 241
-
-
Toye, A.1
Gauguier, D.2
-
30
-
-
3142759596
-
The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population based studies
-
DOI 10.1111/j.1464-5491.2004.01229.x
-
van Dam RM, Hoebee B, Seidell JC, et al. (2004) The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with type 2 diabetes mellitus in two population-based studies. Diabet Med 21:752-758. (Pubitemid 38916221)
-
(2004)
Diabetic Medicine
, vol.21
, Issue.7
, pp. 752-758
-
-
Van Dam, R.M.1
Hoebee, B.2
Seidell, J.C.3
Schaap, M.M.4
Blaak, E.E.5
Feskens, E.J.M.6
-
31
-
-
0035432254
-
New amino acid substitutions in the IRS-2 Gene in finnish and chinese subjects with late-onset type 2 diabetes
-
Wang H, Rissanen J, Miettinen R, et al. (2001) New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes. Diabetes 50:1949-1951. (Pubitemid 33641618)
-
(2001)
Diabetes
, vol.50
, Issue.8
, pp. 1949-1951
-
-
Wang, H.1
Rissanen, J.2
Miettinen, R.3
Karkkainen, P.4
Kekalainen, P.5
Kuusisto, J.6
Mykkanen, L.7
Karhapaa, P.8
Laakso, M.9
-
33
-
-
0029737799
-
Genome scanning for linkage: An overview
-
Whittemore AS (1996) Genome scanning for linkage: an overview. Am J Hum Genet 59:704-716. (Pubitemid 26269049)
-
(1996)
American Journal of Human Genetics
, vol.59
, Issue.3
, pp. 704-716
-
-
Whittemore, A.S.1
-
34
-
-
0032567937
-
Disruption of IRS-2 causes type 2 diabetes in mice
-
DOI 10.1038/36116
-
Withers DJ, Gutierrez JS, Towery H, et al. (1998) Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391:900-904. (Pubitemid 28157668)
-
(1998)
Nature
, vol.391
, Issue.6670
, pp. 900-904
-
-
Withers, D.J.1
Gutierrez, J.S.2
Towery, H.3
Burks, D.J.4
Ren, J.-M.5
Previs, S.6
Zhang, Y.7
Bernal, D.8
Pons, S.9
Shulman, G.I.10
Bonner-Weir, S.11
White, M.F.12
-
35
-
-
9444276572
-
Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset
-
DOI 10.2337/diabetes.53.12.3319
-
Zeggini E, Parkinson J, Halford S, et al. (2004) Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset. Diabetes 53:3319-3322. (Pubitemid 39564510)
-
(2004)
Diabetes
, vol.53
, Issue.12
, pp. 3319-3322
-
-
Zeggini, E.1
Parkinson, J.2
Halford, S.3
Owen, K.R.4
Frayling, T.M.5
Walker, M.6
Hitman, G.A.7
Levy, J.C.8
Sampson, M.J.9
Feskens, E.J.M.10
Hattersley, A.T.11
McCarthy, M.I.12
|