Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects

International Journal of Obesity

Volumn 37, Issue 7, 2013, Pages 986-992

  Rametta, R ^a   Mozzi, E ^a   Dongiovanni, P ^a   Motta, B M ^a   Milano, M ^a   Roviaro, G ^a   Fargion, S ^a   Valenti, L ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Glucokinase; Insulin receptor substrate 2; Insulin resistance; Lipogenesis; Nonalcoholic fatty liver disease; Steatosis

Indexed keywords

GLUCOKINASE; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; PROTEIN KINASE B BETA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR FKHR;

ADULT; AGED; ARTICLE; BODY MASS; DISEASE ASSOCIATION; DISEASE SEVERITY; DISORDERS OF LIPID METABOLISM; DYSLIPIDEMIA; FEMALE; GENE EXPRESSION REGULATION; HUMAN; INSULIN RESISTANCE; LIPID METABOLISM; LIPOGENESIS; LIPOLYSIS; LIVER; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; OBESITY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ADULT; AGED; BLOTTING, WESTERN; FATTY LIVER; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; ITALY; LIPID METABOLISM; LIPOGENESIS; LIVER; MALE; MIDDLE AGED; OBESITY, MORBID; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84880255942     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2012.181     Document Type: Article

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