Understanding the contribution of synonymous mutations to human disease

Nature Reviews Genetics

Volumn 12, Issue 10, 2011, Pages 683-691

  Sauna, Zuben E ^a   Kimchi Sarfaty, Chava ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; GENE PRODUCT; MESSENGER RNA; MICRORNA; MULTIDRUG RESISTANCE PROTEIN 1; SUNITINIB; TACROLIMUS; TRANSFER RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR; WT1 PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ALLELE; ATTENTION DEFICIT DISORDER; CODON USAGE; CONGESTIVE CARDIOMYOPATHY; CROHN DISEASE; CYSTIC FIBROSIS; DISEASE PREDISPOSITION; DRUG ABSORPTION; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; ENTERITIS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC VARIABILITY; HEMOPHILIA B; HUMAN; KIDNEY CARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SARCOIDOSIS; MANDIBULOFACIAL DYSOSTOSIS; PATHOGENESIS; PHARMACOGENETICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; REVIEW; RNA PROCESSING; RNA SPLICING; RNA STRUCTURE; RNA TRANSLATION; SINGLE NUCLEOTIDE POLYMORPHISM; SPLICEOSOME; SYNONYMOUS MUTATION; THERAPY RESISTANCE; TREATMENT OUTCOME; UTERINE CERVIX CANCER; VULVA CANCER;

ANIMALS; COMPREHENSION; DISEASE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MODELS, BIOLOGICAL; PHARMACOGENETICS; POINT MUTATION; RNA PROCESSING, POST-TRANSCRIPTIONAL;

EID: 80052964856     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg3051     Document Type: Review

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