Natural history of β-cell adaptation and failure in type 2 diabetes

Molecular Aspects of Medicine

Volumn 42, Issue , 2015, Pages 19-41

  Alejandro, Emilyn U ^a   Gregg, Brigid ^b   Blandino Rosano, Manuel ^a   Cras Méneur, Corentin ^a   Bernal Mizrachi, Ernesto ^a,c  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

Glucolipotoxicity; Insulin resistance; Islet biology; cell development; cell failure; cell programming

Indexed keywords

ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENETIC PREDISPOSITION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PANCREAS; PANCREAS ISLET BETA CELL; PATHOLOGY; PHYSIOLOGY; PREGNANCY; RODENT;

ANIMALS; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; OXIDATIVE STRESS; PANCREAS; PREGNANCY; RODENTIA;

EID: 84937071614     PISSN: 00982997     EISSN: 18729452     Source Type: Journal    
DOI: 10.1016/j.mam.2014.12.002     Document Type: Review

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