MTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway

Cell Death and Differentiation

Volumn 19, Issue 2, 2012, Pages 310-320

  Kato, H ^a   Nakajima, S ^a   Saito, Y ^a   Takahashi, S ^a   Katoh, R ^a   Kitamura, M ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Akt; endoplasmic reticulum stress; IRE1; mTOR; rapamycin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE PERK; PROTEIN IRE1; PROTEIN KINASE B; RAPAMYCIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; HISTOPATHOLOGY; KIDNEY TUBULE DAMAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; UNFOLDED PROTEIN RESPONSE;

ANIMALS; APOPTOSIS; CELL LINE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; TOR SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS;

MAMMALIA; MUS;

EID: 84855696465     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.98     Document Type: Article

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