Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus

Diabetes

Volumn 61, Issue 5, 2012, Pages 1143-1152

  Demirci, Cem ^a,b   Ernst, Sara ^a   Alvarez Perez, Juan C ^a   Rosa, Taylor ^a   Valle, Shelley ^a   Shridhar, Varsha ^a   Casinelli, Gabriella P ^a   Alonso, Laura C ^a   Vasavada, Rupangi C ^a   García Ocana, Adolfo ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Farmington   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; FORKHEAD TRANSCRIPTION FACTOR; FORKHEAD TRANSCRIPTION FACTOR M1; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; PROLACTIN RECEPTOR; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; STAT5 PROTEIN; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIVISION; CELL EXPANSION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; UPREGULATION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BLOOD GLUCOSE; CELL DEATH; CELL PROLIFERATION; DIABETES, GESTATIONAL; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTE GROWTH FACTOR; HOMEOSTASIS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; PREGNANCY; PROTO-ONCOGENE PROTEINS C-MET; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PROLACTIN; SIGNAL TRANSDUCTION;

EID: 84860585020     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1154     Document Type: Article

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