PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Development

Volumn 122, Issue 3, 1996, Pages 983-995

  Offield, Martin F ^a   Jetton, Tom L ^a   Labosky, Patricia A ^a   Ray, Michael ^a   Stein, Roland W ^a   Magnuson, Mark A ^a   Hogan, Brigid L M ^a   Wright, Christopher V E ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Duodenum; Gene targeting; IDX 1; IPF 1; Pancreas; PDX 1; STF 1; XlHbox8

Indexed keywords

GLUCAGON;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DUODENUM; EMBRYO; ENDOCRINE CELL; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENE TARGETING; HOMEOBOX; INTESTINE EPITHELIUM; MORPHOGENESIS; MOUSE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; RECOMBINANT GENE; REPORTER GENE;

ANIMALS; CHOLECYSTOKININ; DUODENUM; ENDODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; GLUCOSE TRANSPORTER TYPE 2; HETEROZYGOTE; HOMEODOMAIN PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOSACCHARIDE TRANSPORT PROTEINS; PANCREAS; RNA, MESSENGER; SECRETIN; SEROTONIN; TRANS-ACTIVATORS;

EID: 0029868156     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Bonnerot, C. and Nicolas, J. (1993). Application of LacZ gene fusions to postimplantation development. Meth. Enz. 225, 451-469
2. Camper, S. A., Saunders, T. L., Katz, R. W. and Reeves, R. H. (1990). The Pit-1 transcription factor gene is a candidate for the murine Snell dwarf mutation. Genomics 8, 586-590.
3. Cohn, S., Simon, T., Roth, K., Birkenmeier, E., and Gordon, J. (1992). Use of transgenic mice to map cis-acting elements in the Intestinal Fatty Acid Binding Protein Gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium. J Cell Biol. 119, 27-44.
4. Dear, T.N., Colledge, W.H., Carlton, M.B.L., Lavenir, I., Larson, T., Smith, A.J.H.., Warren, A.J., Evans, M.J., Sofroniew, M.V., and Rabbitts, T.H. (1995). The Hoxl 1 gene is essential for cell survival during spleen development. Development 121, 2909-2915.
5. Fire, A., Harrison, S. W. and Dixon, D. (1990). A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans. Gene 93, 189-198.
6. Fitzpatrick, V. D., Percival-Smith, A., Ingles, C. J. and Krause, H. M. (1992). Homeodomain-independent activity of the fushi-tarazu polypeptide in Drosophila embryos. Nature 356, 610-612.
7. Gehring, W. J., Qian, Y. Q., Billeter, M., Furukubo-Tokunaga, K., Schier, A. F., Resendez-Perez, D., Affolter, M., Otting, G. and Wuthrich, K. (1994). Homeodomain-DNA recognition. Cell 78, 211-223.
8. Golosow, N. and Grobstein, C. (1962). Epitheliomesenchymal interaction in pancreatic morphogenesis. Dev. Biol. 4, 242-255.
9. Guz, Y., Montminy, M. R., Stein, R., Leonard, J., Gamer, L. W., Wright, C. V. and Teitelman, G. (1995). Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium, and pancreatic exocrine and endocrine progenitors during ontogeny. Development 121, 11-18.
10. Hogan, B., Beddington, R., Costantini, F. And Lacy, E. (1994) Manipulating the Mouse Embryo: A Laboratory Manual 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
11. Jetton, T. L., Liang, Y., Pettipher, C. C., Zimmerman, E. C., Cox, F. G., Horvath, K., Matschinsky, F. M. And Magnuson, M. (1994). Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. J. Biol. Chem. 269, 3641-3654.
12. Jonsson, J., Carlsson, L., Edlund, T. and Edlund, H. (1994). Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371, 606-609.
13. Krumlauf, R. (1994) Hox genes in vertebrate development. Cell 78, 191-201.
14. Le Douarin, N. M. (1975). An experimental analysis of liver development. Medical Biology 53, 427-455.
15. Leonard, J., Peers, B., Johnson, T., Ferreri, K., Lee, S. and Montminy, M. R. (1993). Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol. Endocrinol. 7, 1275-1283.
16. Li, S., Crenshaw, E. B. 3rd., Rawson, E. J., Simmons, D. M., Swanson, L. W. and Rosenfeld, M. G. (1990). Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature 347, 528-533.
17. McGinnis, W. (1994). A century of homeosis, a decade of homeoboxes. Genetics 3, 607-611.
18. Miller, C. P., McGehee, R. E. Jr. and Habener, J. F. (1994). IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J. 13, 1145-1156.
19. Murphy, P. And Hill, R. E. (1991). Expression of the mouse labial-like homeobox-containing genes. Hox 2.9 and Hox 1 6, during segmentation of the hindbrain. Development 111, 61-74.
20. Ohlsson, H., Karlsson, K. and Edlund, T. (1993). IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J. 12, 4251-4259.
21. Pang, K., Mukonoweshuro, C. and Wong, G. G. (1994). Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas. Proc. Natl. Acad. Sci. USA 91, 9559-9563.
22. Peers, B., Leonard, J., Sharma, S., Teitelman, G. and Montminy, M. R. (1994). Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol. Endocrinol. 8, 1798-1806.
23. Peshavaria, M., Gamer L., Henderson, E., Teitelman, G., Wright, C. and Stein, R. (1994). XlHbox 8, an endoderm-specitic Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol. Endocrinol. 8, 806-816.
24. Roberts, C. W., Shutter, J. R. and Korsmeyer, S. J. (1994). Hoxl 1 controls the genesis of the spleen. Nature 368, 747-749.
25. Roth, K. A., Rubin, D. C., Birkenmeier, E. H. and Gordon, J. I. (1991). Expression of liver fatty acid-binding protein/human growth hormone fusion genes within the enterocyte and enteroendocrine cell populations of fetal transgenic mice. J. Biol. Chem 266, 5949-5954.
26. Scarpelli, D. G. And Rao, M. S. (1981). Differentiation of regenerating pancreatic cells into hepatocyte like cells. Proc. Natl. Acad. Sci. USA 78, 2577-2581.
27. Schneider-Maunoury, S., Topilko, P., Seitandou, T., Levi, G., Cohen-Tannoudji, M., Pournin, S., Babinet, C. and Charnay, P. (1993). Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell 75, 1199-1214.
28. Shaw, J. W. And Latimer, E. O. (1926). Regeneration of pancreatic tissue from the transplanted pancreatic duct in the dog. Am. J. Physiol. 76, 49-53.
29. Solcia, E., Capella, C., Buffa, R., Usellini, L., Fiocca, R. and Sessa, F. (1987). Endocrine cells of the digestive system. In: Physiology of the Gastrointestinal Tract, 2nd ed. L. R. Johnson, ed. Raven Press, New York, pp 111-130.
30. Sweetser, E., Birkenmeier, E. H., Hoppe, P. C., McKeel, D. W., and Gordon, J. G. (1988). Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes. Genes Dev. 2, 1318-1332.
31. Teitelman, G., Alpert, S., Polak, J. M., Martinez, A. and Hanahan, D. (1993). Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide. Development 118, 1031-1039.
32. Thorens, B., Cheng, Z., Brown, D. and Lodish, H. (1990). Liver glucose transporter: a basolateral protein in hepatocytes and intestine and kidney cells. Am. J. Physiol. 259, C279-C285.
33. Wessells, N. K. and Cohen, J. H. (1967). Early pancreas organogenesis: morphogenesis, tissue interactions, and mass effects. Dev. Biol. 15, 237-270.
34. Winnier, G., Blessing, M., Labosky, P. A. and Hogan, B. L. M. (1995). Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9, 2105-2116.
35. Wright, C. V. E., Schnegelsberg, P. and De Robertis, E. M. (1988). XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm. Development 105, 787-794.