Pdx1 maintains β cell identity and function by repressing an α cell program

Cell Metabolism

Volumn 19, Issue 2, 2014, Pages 259-271

  Gao, Tao ^a,b   McKenna, Brian ^c   Li, Changhong ^a   Reichert, Maximilian ^a   Nguyen, James ^a   Singh, Tarjinder ^a   Yang, Chenghua ^a,b   Pannikar, Archana ^a,b   Doliba, Nicolai ^a   Zhang, Tingting ^a   Stoffers, Doris A ^a   Edlund, Helena ^d   Matschinsky, Franz ^a   Stein, Roland ^c   Stanger, Ben Z ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; GLUCAGON; TRANSCRIPTION FACTOR MAFB; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL FUNCTION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE SEVERITY; GENE ACTIVATION; GENE DELETION; GENE REPRESSION; GENETIC TRANSCRIPTION; HYPERGLYCEMIA; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; GLUCAGON-SECRETING CELLS; HOMEODOMAIN PROTEINS; INSULIN-SECRETING CELLS; MAFB TRANSCRIPTION FACTOR; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANS-ACTIVATORS;

EID: 84893510559     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.12.002     Document Type: Article

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