Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide

Diabetologia

Volumn 55, Issue 4, 2012, Pages 1035-1047

  Park, Y J ^a   Lee, S ^a   Kieffer, T J ^a,b   Warnock, G L ^a   Safikhan, N ^a   Speck, M ^a   Hao, Z ^c   Woo, M ^c   Marzban, L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Amylin; Amyloid; Beta cell apoptosis; Fas receptor; Islet amyloid polypeptide; Type 2 diabetes

Indexed keywords

AMYLIN; CASPASE 3; FAS ANTIGEN; INTERLEUKIN 1BETA; SMALL INTERFERING RNA;

ANIMAL CELL; ANTIBODY LABELING; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; FAS GENE; GENE; GENE DELETION; GENOTYPE; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULIN RESPONSE; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; VIRAL GENE DELIVERY SYSTEM;

EID: 84862826030     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2451-2     Document Type: Article

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