Genetic susceptibility to type 2 diabetes and obesity: From genome-wide association studies to rare variants and beyond

Diabetologia

Volumn 57, Issue 8, 2014, Pages 1528-1541

  Grarup, Niels ^a   Sandholt, Camilla H ^a   Hansen, Torben ^a,b   Pedersen, Oluf ^a  

^a Capital Region   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Adiposity; Body mass index; Genetics; Genome wide association; Glycaemic traits; Obesity; Review; Sequencing; Type 2 diabetes

Indexed keywords

COBLL1 PROTEIN; GLUCOSE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 1; INSULIN; PROTEIN; UNCLASSIFIED DRUG;

ABDOMINAL OBESITY; ANCESTRY GROUP; BODY COMPOSITION; BODY FAT DISTRIBUTION; BODY MASS; CLINICAL FEATURE; EPIDEMIOLOGY; FAMILY STUDY; FOLLOW UP; GENE EXPRESSION; GENE FREQUENCY; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; GENETIC VARIABILITY; GENETICS; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HEREDITY; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESPONSE; INSULIN SENSITIVITY; INTRON; METABOLIC DISORDER; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; WAIST CIRCUMFERENCE; WAIST HIP RATIO; GENETIC PREDISPOSITION; INSULIN RESISTANCE;

DIABETES MELLITUS, TYPE 2; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INSULIN RESISTANCE; OBESITY;

EID: 84904745172     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3270-4     Document Type: Review

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