Evidence of endoplasmic reticulum stress mediating cell death in transplanted human islets

Cell Transplantation

Volumn 21, Issue 5, 2012, Pages 889-900

  Negi, Sarita ^a,b   Park, Soon Hyang ^a,b   Jetha, Arif ^a,b   Aikin, Reid ^a,b   Tremblay, Michel ^c   Paraskevas, Steven ^a,b  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Apoptosis; Endoplasmic reticulum (ER) stress; Human; Islet; Transplantation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; CASPASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE; CELL DEATH; CELL ISOLATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GRAFT RECIPIENT; GRAFT SURVIVAL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; APOPTOSIS; CASPASE 3; DIABETES MELLITUS, EXPERIMENTAL; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; GLUCAGON; HEAT-SHOCK PROTEINS; HUMANS; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 8; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS;

EID: 84862579292     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368911X603639     Document Type: Article

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