The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets

Diabetologia

Volumn 57, Issue 4, 2014, Pages 765-775

  Park, Yoo Jin ^a   Woo, Minna ^b,c   Kieffer, Timothy J ^a,d   Hakem, Razqallah ^c   Safikhan, Nooshin ^a   Yang, Fan ^a   Ao, Ziliang ^a   Warnock, Garth L ^a   Marzban, Lucy ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Amylin; Amyloid; Beta cell apoptosis; Caspase 8; Islet amyloid polypeptide; Islet transplantation; Type 2 diabetes

Indexed keywords

AMYLIN; AMYLOID; CASPASE 3; CASPASE 8; FLICE INHIBITORY PROTEIN; INTERLEUKIN 1BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ADULT; AMYLOID; ANIMALS; CASPASE 3; CASPASE 8; FEMALE; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MIDDLE AGED;

EID: 84896077515     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3152-1     Document Type: Article

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