Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger

Diabetes and Metabolism

Volumn 33, Issue 5, 2007, Pages 340-345

  Lupi, R ^a   Del Guerra, S ^a   Mancarella, R ^a   Novelli, M ^a   Valgimigli, L ^b   Pedulli, G F ^b   Paolini, M ^b   Soleti, A ^c   Filipponi, F ^a   Mosca, F ^a   Boggi, U ^a   Del Prato, S ^a   Masiello, P ^a   Marchetti, P ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Medestea Research   (Italy)

Author keywords

Antioxidant; Human pancreatic islet; Insulin secretion; Oxidative stress; Type 2 diabetes

Indexed keywords

3 NITROTYROSINE; ANTIOXIDANT; BIS(HYDROXY 2,2,6,6 TETRAMETHYL 4 PIPERIDINYL)DECANDIOATE DI HYDROCHLORIDE; CATALASE; GLUTATHIONE PEROXIDASE; INSULIN; REACTIVE OXYGEN METABOLITE; SCAVENGER; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GENE EXPRESSION; HUMAN; IN VITRO STUDY; INSULIN RELEASE; MALE; MICROSCOPY; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PANCREAS ISLET; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION;

ANTIOXIDANTS; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; GLUCOSE; HUMANS; INSULIN; ISLETS OF LANGERHANS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TYROSINE;

EID: 35649013806     PISSN: 12623636     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabet.2007.03.005     Document Type: Article

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