Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia

Journal of Biological Chemistry

Volumn 275, Issue 20, 2000, Pages 15399-15406

  Vasavada, Rupangi C ^a,e   Garcia Ocaña, Adolfo ^a   Zawalich, Walter S ^b   Sorenson, Robert L ^c   Dann, Pamela ^b   Syed, Mushtaq ^a   Ogren, Linda ^d   Talamantes, Frank ^d   Stewart, Andrew F ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF NURSING   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; PLACENTA LACTOGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL HYPERPLASIA; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE TARGETING; HYPOGLYCEMIA; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BLOOD GLUCOSE; CELL DIVISION; CELL SIZE; DIABETES MELLITUS, EXPERIMENTAL; FASTING; GLUCOSE; HYPOGLYCEMIA; INSULIN; ISLETS OF LANGERHANS; MICE; MICE, TRANSGENIC; PLACENTAL LACTOGEN; POSTPRANDIAL PERIOD; PROMOTER REGIONS (GENETICS); RATS;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0034686028     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.20.15399     Document Type: Article

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