A central, role for JNK in obesity and insulin resistance

Nature

Volumn 420, Issue 6913, 2002, Pages 333-336

  Hirosumi, Jim ^a   Tuncman, Gürol ^a   Chang, Lufen ^b   Görgün, Cem Z ^a   Uysal, K Teoman ^a   Maeda, Kazuhisa ^a   Karin, Michael ^b   Hotamisligil, Gökhan S ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DISEASES; FATTY ACIDS; INSULIN;

OBESITY;

ENZYMES;

CYTOKINE; FATTY ACID; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LIPID; STRESS ACTIVATED PROTEIN KINASE;

MEDICINE;

ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; GENE MUTATION; GLUCOSE HOMEOSTASIS; HORMONE ACTION; INFLAMMATION; INSULIN RESISTANCE; INSULIN RESPONSE; LIPID DIET; LIPID METABOLISM; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DIET; DISEASE MODELS, ANIMAL; GENE DELETION; HOMEOSTASIS; HYPERINSULINISM; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; MICE; MICE, KNOCKOUT; MICE, OBESE; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; OBESITY; PHOSPHOPROTEINS; PHOSPHORYLATION; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0037153158     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01137     Document Type: Article

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