Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells

Journal of Biological Chemistry

Volumn 276, Issue 41, 2001, Pages 38052-38060

  Tremblay, Frédéric ^b   Marette, André ^a  

^a LAVAL UNIVERSITY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOMARKERS; CELLS; DEGRADATION; GLUCOSE; INSULIN;

PHOSPHORYLATION; POTENT MODULATORS;

ENZYME INHIBITION;

INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; AMINO ACID; GLUCOSE; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; ONCOPROTEIN; PHOSPHOPROTEIN; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; S6 KINASE; TYROSINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; GLUCOSE TRANSPORT; INHIBITION KINETICS; INSULIN RESISTANCE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; CELL LINE; CYTOLOGY; ENZYME ACTIVATION; HYDROLYSIS; METABOLISM; PHOSPHORYLATION; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACIDS; BIOLOGICAL TRANSPORT; CELL LINE; ENZYME ACTIVATION; FEEDBACK; GLUCOSE; HYDROLYSIS; INSULIN; INSULIN RESISTANCE; MUSCLE, SKELETAL; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0035851205     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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