Susceptibility to fatty acid-induced β-cell dysfunction is enhanced in prediabetic diabetes-prone biobreeding rats: A potential link between β-cell lipotoxicity and islet inflammation

Endocrinology

Volumn 154, Issue 1, 2013, Pages 89-101

  Tang, Christine ^a   Naassan, Anthony E ^a   Chamson Reig, Astrid ^b   Koulajian, Khajag ^a   Goh, Tracy T ^a   Yoon, Frederick ^a   Oprescu, Andrei I ^a   Ghanim, Husam ^c   Lewis, Gary F ^a   Dandona, Paresh ^c   Donath, Marc Y ^d,e   Ehses, Jan A ^f   Arany, Edith ^b   Giacca, Adria ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY AT BUFFALO   (United States)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; INTERLEUKIN 10; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL EXPERIMENT; ARTICLE; CELL INFILTRATION; CELLULAR SECRETION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EX VIVO STUDY; FEMALE; IMPAIRED GLUCOSE TOLERANCE; INFLAMMATION; INSULIN RELEASE; INSULIN RESISTANCE; LIPOTOXICITY; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ANIMALS; CHEMOKINE CCL2; EMULSIONS; FATTY ACIDS; FEMALE; IMMUNOHISTOCHEMISTRY; INSULIN-SECRETING CELLS; INTERLEUKIN-10; ISLETS OF LANGERHANS; PHOSPHOLIPIDS; PREDIABETIC STATE; RATS; RATS, INBRED BB; REAL-TIME POLYMERASE CHAIN REACTION; SOYBEAN OIL;

EID: 84871682971     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1720     Document Type: Article

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