Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic β cells

Journal of Clinical Investigation

Volumn 117, Issue 10, 2007, Pages 2869-2876

  Zhong, Lingwen ^a   Georgia, Senta ^a   Tschen, Shuen Ing ^a   Nakayama, Keiko ^b   Nakayama, Keiichi ^b   Bhushan, Anil ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P27; S PHASE KINASE ASSOCIATED PROTEIN 2; UBIQUITIN PROTEIN LIGASE;

ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; ENDOREDUPLICATION; GLUCOSE TOLERANCE; HYPOINSULINEMIA; INSULIN RESISTANCE; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; POLYPLOIDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION;

ANIMALS; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; GENE DELETION; GLUCOSE; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MICE; MICE, MUTANT STRAINS; POLYPLOIDY; S-PHASE KINASE-ASSOCIATED PROTEINS;

EID: 34948821871     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI32198     Document Type: Article

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