Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells

Diabetologia

Volumn 54, Issue 7, 2011, Pages 1766-1776

  Chan, J Y ^a   Cooney, G J ^a   Biden, T J ^a   Laybutt, D R ^a  

^a ST VINCENT S HOSPITAL   (Australia)

Author keywords

Apoptosis; Cytokines; Endoplasmic reticulum stress; Islets; Nitric oxide; Pancreatic beta cell; Type 1 diabetes

Indexed keywords

CHAPERONE; CYTOKINE; GAMMA INTERFERON; INITIATION FACTOR 2ALPHA; INTERLEUKIN 1BETA; MESSENGER RNA; N(G) METHYLARGININE; NITRIC OXIDE; PHOSPHOTRANSFERASE; PKR LIKE ER KINASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATF3 GENE; CELL ISOLATION; CHOP GENE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE CONTROL; GENE EXPRESSION; MARKER GENE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRIB3 GENE; UNFOLDED PROTEIN RESPONSE; WILD TYPE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; CYTOKINES; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; UNFOLDED PROTEIN RESPONSE;

EID: 79959715318     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2139-z     Document Type: Article

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