Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes

Molecular Endocrinology

Volumn 26, Issue 7, 2012, Pages 1203-1212

  Yang, Beatrice T ^a   Dayeh, Tasnim A ^a   Volkov, Petr A ^a   Kirkpatrick, Clare L ^b   Malmgren, Siri ^a   Jing, Xingjun ^a   Renström, Erik ^a   Wollheim, Claes B ^b   Nitert, Marloes Dekker ^a   Ling, Charlotte ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; MESSENGER RNA; TRANSCRIPTION FACTOR PDX 1;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIABETIC PATIENT; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; FEMALE; GENE CONTROL; GENE EXPRESSION; HORMONE RELEASE; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; INSULIN RELEASE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE;

DIABETES MELLITUS, TYPE 2; DNA METHYLATION; FEMALE; GLUCOSE; HOMEODOMAIN PROTEINS; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; PANCREAS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; TRANS-ACTIVATORS;

MUS;

EID: 84863334811     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2012-1004     Document Type: Article

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