Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

Journal of Clinical Investigation

Volumn 122, Issue 10, 2012, Pages 3516-3528

  Xuan, Shouhong ^a   Borok, Matthew J ^a   Decker, Kimberly J ^b   Battle, Michele A ^c   Duncan, Stephen A ^c   Hale, Michael A ^d   Macdonald, Raymond J ^d   Sussel, Lori ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE A; CARBOXYPEPTIDASE A1; NEUROGENIN 3; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; UNCLASSIFIED DRUG;

AGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE DELETION; MORPHOGENESIS; MOUSE; NONHUMAN; PANCREAS; PANCREAS DISEASE; PANCREATIC AGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; STEM CELL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; CARBOXYPEPTIDASES A; CELL DIFFERENTIATION; CELL DIVISION; CELL LINEAGE; DISEASE MODELS, ANIMAL; ENDODERM; EPITHELIAL CELLS; GATA4 TRANSCRIPTION FACTOR; GATA6 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GENOTYPE; GESTATIONAL AGE; HYPERGLYCEMIA; INSULIN; MICE; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; ORGANOGENESIS; PANCREAS; TRANSCRIPTION, GENETIC;

EID: 84867174750     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI63352     Document Type: Article

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