-
1
-
-
0028903027
-
Molecular defects of the insulin receptor gene
-
Accili D: Molecular defects of the insulin receptor gene. Diabetes Metab Reviews 11: 47-62, 1995.
-
(1995)
Diabetes Metab Reviews
, vol.11
, pp. 47-62
-
-
Accili, D.1
-
2
-
-
13344277357
-
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
-
Accili D, Drago J, Lee EC, Johnson MD, Cool MH, Salavatore P, Asico LD, José PA, Taylor SI, Westphal H: Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Nat Genet 12: 106-10, 1996.
-
(1996)
Nat Genet
, vol.12
, pp. 106-110
-
-
Accili, D.1
Drago, J.2
Lee, E.C.3
Johnson, M.D.4
Cool, M.H.5
Salavatore, P.6
Asico, L.D.7
José, P.A.8
Taylor, S.I.9
Westphal, H.10
-
3
-
-
0029024314
-
Cloning of the β-cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
-
Aguilar-Bryan L, Nichols CG, Wechsler SW, Clement JP, Boyd AE, Gonzalez G, Herrera-Sosa H, Nguy K, Bryan J, Nelson DA: Cloning of the β-cell high-affinity sulfonylurea receptor: A regulator of insulin secretion. Science 268: 423-426. 1995.
-
(1995)
Science
, vol.268
, pp. 423-426
-
-
Aguilar-Bryan, L.1
Nichols, C.G.2
Wechsler, S.W.3
Clement, J.P.4
Boyd, A.E.5
Gonzalez, G.6
Herrera-Sosa, H.7
Nguy, K.8
Bryan, J.9
Nelson, D.A.10
-
4
-
-
0031020002
-
Independent requirement for ISL1 in formation of mesenchyme and islet cells
-
Ahlgren U, Pfaff SL, Jessel TM, Edlund T, Edlund H: Independent requirement for ISL1 in formation of mesenchyme and islet cells. Nature 385: 257-60, 1997.
-
(1997)
Nature
, vol.385
, pp. 257-260
-
-
Ahlgren, U.1
Pfaff, S.L.2
Jessel, T.M.3
Edlund, T.4
Edlund, H.5
-
5
-
-
0032525981
-
Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
-
Ahlgren U, Jonsson J, Jonsson L, Simu K, Edlund H: beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev 12: 1763-1768, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 1763-1768
-
-
Ahlgren, U.1
Jonsson, J.2
Jonsson, L.3
Simu, K.4
Edlund, H.5
-
6
-
-
0027233603
-
Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme
-
Alessi DR, Street AJ, Cohen PTW: Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme. Eur. J. Biochem 213: 1055-1066, 1993.
-
(1993)
Eur J Biochem
, vol.213
, pp. 1055-1066
-
-
Alessi, D.R.1
Street, A.J.2
Cohen, P.T.W.3
-
7
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA: Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15: 6541-6551, 1996.
-
(1996)
EMBO J
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
8
-
-
0031127305
-
Characterization of a phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha
-
Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB, Cohen P: Characterization of a phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha. Curr. Biol. 7: 261-269, 1997a.
-
(1997)
Curr Biol
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
Cohen, P.7
-
9
-
-
12644301164
-
3-Phosphoinositide-dependent protein kinase-1 (PDK1): Structural and functional homology with the drosophila DSTPK 61 kinase
-
Alessi DR, Deak M, Casamayor A, Cauwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A, Bownes M: 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the drosophila DSTPK61 kinase. Curr. Biol. 7: 776-789, 1997b.
-
(1997)
Curr Biol
, vol.7
, pp. 776-789
-
-
Alessi, D.R.1
Deak, M.2
Casamayor, A.3
Cauwell, F.B.4
Morrice, N.5
Norman, D.G.6
Gaffney, P.7
Reese, C.B.8
MacDougall, C.N.9
Harbison, D.10
Ashworth, A.11
Bownes, M.12
-
10
-
-
0027367546
-
Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin dependent diabetes mellitus
-
Almind K, Bjørbæk C, Vestergaard H, Hansen T, Echwald S, Pedersen O: Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin dependent diabetes mellitus. Lancet 342: 828-832, 1993.
-
(1993)
Lancet
, vol.342
, pp. 828-832
-
-
Almind, K.1
Bjørbæk, C.2
Vestergaard, H.3
Hansen, T.4
Echwald, S.5
Pedersen, O.6
-
11
-
-
0029893417
-
A common amino acid polymorphism in the insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies
-
Almind K, Inoue G, Pedersen O, Kahn CR: A common amino acid polymorphism in the insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies. J. Clin. Invest. 97: 2569-2575, 1996.
-
(1996)
J Clin Invest
, vol.97
, pp. 2569-2575
-
-
Almind, K.1
Inoue, G.2
Pedersen, O.3
Kahn, C.R.4
-
12
-
-
0033237647
-
Discovery of a Met300Val variant in Shc and studies of its relationship to birth weight and length, impaired insulin secretion, insulin resistance, and type 2 diabetes mellitus
-
Almind K, Ahlgren MG, Hansen T, Urhammer SA, Clausen JO, Pedersen O: Discovery of a Met300Val variant in Shc and studies of its relationship to birth weight and length, impaired insulin secretion, insulin resistance, and type 2 diabetes mellitus. J Clin Endocrinol Metab 84: 2241-44, 1999a.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 2241-2244
-
-
Almind, K.1
Ahlgren, M.G.2
Hansen, T.3
Urhammer, S.A.4
Clausen, J.O.5
Pedersen, O.6
-
13
-
-
0032822218
-
Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: Evaluation of their relation with alterations in insulin secretion and insulin sensitivity
-
Almind K, Frederiksen SK, Bernal D, Hansen T, Ambye L, Urhammer S, Ekstrøm CT, Berglund L, reneland R, Lithell H, White MF, Van Obberghen E, Pedersen O: Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity. Diabetologia 42: 1244-49, 1999b.
-
(1999)
Diabetologia
, vol.42
, pp. 1244-1249
-
-
Almind, K.1
Frederiksen, S.K.2
Bernal, D.3
Hansen, T.4
Ambye, L.5
Urhammer, S.6
Ekstrøm, C.T.7
Berglund, L.8
Reneland, R.9
Lithell, H.10
White, M.F.11
Van Obberghen, E.12
Pedersen, O.13
-
14
-
-
0029091079
-
A new look at the biogenesis of glycogen
-
Alonso MD, Lomako J, Lomako WM, Whelan WJ: A new look at the biogenesis of glycogen. FASEB J 9: 1126-39, 1995.
-
(1995)
FASEB J
, vol.9
, pp. 1126-1139
-
-
Alonso, M.D.1
Lomako, J.2
Lomako, W.M.3
Whelan, W.J.4
-
15
-
-
0029064102
-
Catalytic activities of glycogenin additional to autocatalytic self-glucosylation
-
Alonso MD, Lomako J, Lomako WM, Whelan WJ: Catalytic activities of glycogenin additional to autocatalytic self-glucosylation. J Biol Chem 270: 15315-19, 1996.
-
(1996)
J Biol Chem
, vol.270
, pp. 15315-15319
-
-
Alonso, M.D.1
Lomako, J.2
Lomako, W.M.3
Whelan, W.J.4
-
16
-
-
0033624575
-
The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl M-C, nemesh J, Lane CR, Schaffner SF, Bolk S, Brewer C, Tuomi T, gaudet D, Hudson TJ, Daly M, Groop L, Lander ES: The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80, 2000.
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.-C.5
Nemesh, J.6
Lane, C.R.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
Tuomi, T.11
Gaudet, D.12
Hudson, T.J.13
Daly, M.14
Groop, L.15
Lander, E.S.16
-
17
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic M, Alessi DR, Meier R, Fernandez A, Lamb NJC, Frech M, Cron P, Cohen P, Lueocq JM, Hemmings BA: Role of translocation in the activation and function of protein kinase B. J. Biol. Chem. 272, 50: 31515-31524, 1997.
-
(1997)
J Biol Chem
, vol.272
, Issue.50
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.C.5
Frech, M.6
Cron, P.7
Cohen, P.8
Lueocq, J.M.9
Hemmings, B.A.10
-
18
-
-
0033043389
-
Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase
-
Andjelkovic M, Maira SM, Cron P, Parker PJ, Hemmings BA: Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase. Mol Cell Biol 19: 5061-72, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5061-5072
-
-
Andjelkovic, M.1
Maira, S.M.2
Cron, P.3
Parker, P.J.4
Hemmings, B.A.5
-
19
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelquist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H: Notch signalling controls pancreatic cell differentiation. Nature 400: 877-81, 1999.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelquist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe De Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
20
-
-
0028032895
-
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
-
Araki E, Lipes MA, Patti ME, Bruning JC, Haag B 3rd, Johnson RS, Kahn CR: Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 372: 186-190, 1994.
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Bruning, J.C.4
Haag III, B.5
Johnson, R.S.6
Kahn, C.R.7
-
21
-
-
0032856044
-
Insulin sensitivity, glucose effectiveness, and insulin secretion in nondiabetic offspring of patients with non-insulin dependent diabetes mellitus: A cross-sectional study
-
Araujo-Vilar D, Garcia-Estevez DA, Cabezas-Cerrato J: Insulin sensitivity, glucose effectiveness, and insulin secretion in nondiabetic offspring of patients with non-insulin dependent diabetes mellitus: a cross-sectional study. Metabolism 48: 978-83, 1999.
-
(1999)
Metabolism
, vol.48
, pp. 978-983
-
-
Araujo-Vilar, D.1
Garcia-Estevez, D.A.2
Cabezas-Cerrato, J.3
-
22
-
-
0023240110
-
Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 diabetes (non-insulin-dependent) diabetes mellitus
-
Arner P, pollare T, Lithell H, Livingston JN: Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 diabetes (non-insulin-dependent) diabetes mellitus. Diabetologia 30: 437-40, 1987.
-
(1987)
Diabetologia
, vol.30
, pp. 437-440
-
-
Arner, P.1
Pollare, T.2
Lithell, H.3
Livingston, J.N.4
-
23
-
-
0034052341
-
Lack of association of the Ala45Thr variant in the BETA2/NeuroD1 with type 1 diabetes in Japanese
-
Awata T, Inoue K, Inoue I, abe T, Takino H, Kanazawa Y, Katayama S: Lack of association of the Ala45Thr variant in the BETA2/NeuroD1 with type 1 diabetes in Japanese. Diabetes Res Clin Pract 49: 61-63, 2000.
-
(2000)
Diabetes Res Clin Pract
, vol.49
, pp. 61-63
-
-
Awata, T.1
Inoue, K.2
Inoue, I.3
Abe, T.4
Takino, H.5
Kanazawa, Y.6
Katayama, S.7
-
25
-
-
0031803108
-
Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85α): Preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima Women
-
Baier LJ, Wiedrich C, Hanson RL, Bogardus C: Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85α): Preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima Women. Diabetes 47: 973-975, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 973-975
-
-
Baier, L.J.1
Wiedrich, C.2
Hanson, R.L.3
Bogardus, C.4
-
26
-
-
0033797241
-
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance
-
Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen G-Q, mott D, knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI, Bogardus C: A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 106: R69-R73, 2000.
-
(2000)
J Clin Invest
, vol.106
-
-
Baier, L.J.1
Permana, P.A.2
Yang, X.3
Pratley, R.E.4
Hanson, R.L.5
Shen, G.-Q.6
Mott, D.7
Knowler, W.C.8
Cox, N.J.9
Horikawa, Y.10
Oda, N.11
Bell, G.I.12
Bogardus, C.13
-
27
-
-
0029984663
-
The human skeletal muscle glycogenin gene: cDNA, tissue expression and chromosomal localization
-
Barbetti F, Rocchi M, Bossolasco M, Cordera R, Sbraccia P, Finelli P, Consalez GG: The human skeletal muscle glycogenin gene: cDNA, tissue expression and chromosomal localization. Biochem. Biophys. Res. Comm. 220: 72-77, 1996.
-
(1996)
Biochem Biophys Res Comm
, vol.220
, pp. 72-77
-
-
Barbetti, F.1
Rocchi, M.2
Bossolasco, M.3
Cordera, R.4
Sbraccia, P.5
Finelli, P.6
Consalez, G.G.7
-
28
-
-
0025324634
-
Localization of the gene encoding a type 1 protein phosphatase catalytic subunit to human chromosome band 11q13
-
Barker HM, Jones TA, da Cruz e Silva EF, Spurr NK, Sheer D, Cohen PTW: Localization of the gene encoding a type 1 protein phosphatase catalytic subunit to human chromosome band 11q13. Genomics 7: 159-166, 1990.
-
(1990)
Genomics
, vol.7
, pp. 159-166
-
-
Barker, H.M.1
Jones, T.A.2
Da Cruz E Silva, E.F.3
Spurr, N.K.4
Sheer, D.5
Cohen, P.T.W.6
-
29
-
-
0027171705
-
Sequence of protein serine/threonine phosphatase 1 gamma and localization of the gene (PP1CC) encoding it to chromosome bands 12q24.1-q24.2
-
Barker HM, Craig SP, Spurr NK, Cohen PTW: Sequence of protein serine/threonine phosphatase 1 gamma and localization of the gene (PP1CC) encoding it to chromosome bands 12q24. 1-q24.2. Biochem Biophis Acta 1178: 228-233, 1993.
-
(1993)
Biochem Biophis Acta
, vol.1178
, pp. 228-233
-
-
Barker, H.M.1
Craig, S.P.2
Spurr, N.K.3
Cohen, P.T.W.4
-
30
-
-
0028097766
-
Three genes for protein phosphatase 1 map to different human chromosomes: Sequence, expression and gene localization of protein serine/threonine phosphatase 1 beta (PP1CB)
-
Barker HM, Brewis ND, Street AJ, Spurr NK, Cohen PTW: Three genes for protein phosphatase 1 map to different human chromosomes: Sequence, expression and gene localization of protein serine/threonine phosphatase 1 beta (PP1CB). Biochem Biophis Acta 1220: 212-218, 1994.
-
(1994)
Biochem Biophis Acta
, vol.1220
, pp. 212-218
-
-
Barker, H.M.1
Brewis, N.D.2
Street, A.J.3
Spurr, N.K.4
Cohen, P.T.W.5
-
31
-
-
0019870959
-
Diabetes in identical twins
-
Barnett AH, Eff C, Leslie RDG, Pyke DA: Diabetes in identical twins. Diabetologia 20: 87-93, 1981.
-
(1981)
Diabetologia
, vol.20
, pp. 87-93
-
-
Barnett, A.H.1
Eff, C.2
Leslie, R.D.G.3
Pyke, D.A.4
-
32
-
-
0035084073
-
The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance
-
Baroni MG, Arca M, Sentinelli F, Buzzetti R, Capici F, Lovari S, Vitale M, Romeo S, Di Mario U: The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance. Diabetologia 44: 367-372, 2001.
-
(2001)
Diabetologia
, vol.44
, pp. 367-372
-
-
Baroni, M.G.1
Arca, M.2
Sentinelli, F.3
Buzzetti, R.4
Capici, F.5
Lovari, S.6
Vitale, M.7
Romeo, S.8
Di Mario, U.9
-
33
-
-
0033599038
-
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso I, Gurnell M, Crowley VEF, Agostini M, Schwabe JW Soos MA, Li Maslen G, Williams TDM, Lewis H, Schafer AJ, Chatterlee VKK, O'Rahilly SO: Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402: 880-83, 1999.
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
Gurnell, M.2
Crowley, V.E.F.3
Agostini, M.4
Schwabe, J.W.5
Soos, M.A.6
Li Maslen, G.7
Williams, T.D.M.8
Lewis, H.9
Schafer, A.J.10
Chatterlee, V.K.K.11
O'Rahilly, S.O.12
-
34
-
-
0008499455
-
Natural variants of human p85α phosphoinositide-3 kinase in severe insulin resistance: A novel variant with impaired insulin stimulated lipid kinase activity
-
Baynes KCR, Beeton CA, Panatyotou G, Stein R, Soos M, Hansen T, Simpson H, O'Rahilly S Shepherd PR, Whitehead JP: Natural variants of human p85α phosphoinositide-3 kinase in severe insulin resistance: a novel variant with impaired insulin stimulated lipid kinase activity. Diabetologia 43: 321-331, 2000.
-
(2000)
Diabetologia
, vol.43
, pp. 321-331
-
-
Baynes, K.C.R.1
Beeton, C.A.2
Panatyotou, G.3
Stein, R.4
Soos, M.5
Hansen, T.6
Simpson, H.7
O'Rahilly, S.8
Shepherd, P.R.9
Whitehead, J.P.10
-
35
-
-
0031667127
-
Association of the Pro12Ala variant in the peroxisome proliferator-activator receptor-2γ gene with obesity in two Caucasian populations
-
Beamer BA, Yen CJ, Andersen RE, Muller D, Elahi D, Cheskin LJ, Andres R, Roth J, Shuldiner AR: Association of the Pro12Ala variant in the peroxisome proliferator-activator receptor-2γ gene with obesity in two Caucasian populations. Diabetes 47: 1806-8, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 1806-1808
-
-
Beamer, B.A.1
Yen, C.J.2
Andersen, R.E.3
Muller, D.4
Elahi, D.5
Cheskin, L.J.6
Andres, R.7
Roth, J.8
Shuldiner, A.R.9
-
36
-
-
0028091753
-
Metabolic and genetic characterization of prediabetic states - Sequence of events leading to non-insulin-dependent diabetes-mellitus
-
Beck-Nielsen H, Groop LC (1994) Metabolic and genetic characterization of prediabetic states - sequence of events leading to non-insulin-dependent diabetes-mellitus. J Clin Inv; 94(5): 1714-1721.
-
(1994)
J Clin Inv
, vol.94
, Issue.5
, pp. 1714-1721
-
-
Beck-Nielsen, H.1
Groop, L.C.2
-
37
-
-
0032757985
-
Evidence of a novel type 2 diabetes locus 50 cM centromeric to NIDDM on chromosome 12
-
Bektas A, Suprenant ME, Wogan LT, Plenghidya N, Rich SS, Warram JH, Krolewski AS, Doria A: Evidence of a novel type 2 diabetes locus 50 cM centromeric to NIDDM on chromosome 12. Diabetes 48: 2246-51, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 2246-2251
-
-
Bektas, A.1
Suprenant, M.E.2
Wogan, L.T.3
Plenghidya, N.4
Rich, S.S.5
Warram, J.H.6
Krolewski, A.S.7
Doria, A.8
-
38
-
-
0033048456
-
Exclusion of insulin receptor substrate-2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes
-
Bektas A, Warram JH, White MF, Krolewski AS, Doria A: Exclusion of insulin receptor substrate-2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes. Diabetes 48: 640-42, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 640-642
-
-
Bektas, A.1
Warram, J.H.2
White, M.F.3
Krolewski, A.S.4
Doria, A.5
-
39
-
-
0026032055
-
Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q
-
Bell GI, Xiang KS, Newman MV, Wu SH, Wright LG, Fajans SS, Spielman RS, Cox NJ: Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q. Proc Natl Acad Sci USA 88: 1484-1488, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1484-1488
-
-
Bell, G.I.1
Xiang, K.S.2
Newman, M.V.3
Wu, S.H.4
Wright, L.G.5
Fajans, S.S.6
Spielman, R.S.7
Cox, N.J.8
-
40
-
-
0028871202
-
Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
-
Bennett ST, Lucassen AM, Gough SCL, Powell EE, Undlien DE, Pritchard LE, Merriman ME, Kawaguchi Y, Dronsfield MJ, Pociot F, Nerup J, Bouzekri N, Cambon-Thornsen A, Rønningen KS, Barnett AH, Bain SC, Todd JA: Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nature Genetics 9: 284-292, 1995.
-
(1995)
Nature Genetics
, vol.9
, pp. 284-292
-
-
Bennett, S.T.1
Lucassen, A.M.2
Gough, S.C.L.3
Powell, E.E.4
Undlien, D.E.5
Pritchard, L.E.6
Merriman, M.E.7
Kawaguchi, Y.8
Dronsfield, M.J.9
Pociot, F.10
Nerup, J.11
Bouzekri, N.12
Cambon-Thornsen, A.13
Rønningen, K.S.14
Barnett, A.H.15
Bain, S.C.16
Todd, J.A.17
-
41
-
-
0344044252
-
Overexpression of protein targeting to glycogen (PTG) in rat hepatocytes causes profound activation of glycogen synthesis independent of normal hormone- and substrate-mediated regulatory mechanisms
-
Bergman HK, O'Doherty RM, Anderson P, Newgaard CB: Overexpression of protein targeting to glycogen (PTG) in rat hepatocytes causes profound activation of glycogen synthesis independent of normal hormone- and substrate-mediated regulatory mechanisms. J Biol Chem 279: 264221-5, 1998.
-
(1998)
J Biol Chem
, vol.279
, pp. 264221-264225
-
-
Bergman, H.K.1
O'Doherty, R.M.2
Anderson, P.3
Newgaard, C.B.4
-
42
-
-
0031803329
-
Insulin receptor substrate-2 amino acid polymorphyisms are not associated with random tye 2 diabetes among Caucasians
-
Bernal D, Almind K, Yenush L, Ayoub M, Zhang Y, Rosshani L, Larsson C, Pedersen O, White MF: Insulin receptor substrate-2 amino acid polymorphyisms are not associated with random tye 2 diabetes among Caucasians. Diabetes 47: 976-79, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 976-979
-
-
Bernal, D.1
Almind, K.2
Yenush, L.3
Ayoub, M.4
Zhang, Y.5
Rosshani, L.6
Larsson, C.7
Pedersen, O.8
White, M.F.9
-
43
-
-
0032768284
-
Glucose metabolism and beta-cell mass in adult offspring of rats protein and/or energy restricted during the last week of pregnancy
-
Bertin E, Gangnerau MN, Bailbe D, Portha B: Glucose metabolism and beta-cell mass in adult offspring of rats protein and/or energy restricted during the last week of pregnancy. Am J Physiol 277: E11-17, 1999.
-
(1999)
Am J Physiol
, vol.277
-
-
Bertin, E.1
Gangnerau, M.N.2
Bailbe, D.3
Portha, B.4
-
44
-
-
0031057526
-
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation
-
Bjornholm M, Kawano Y, Lehtihet M, Zierath JR: Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes 46: 524-27, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 524-527
-
-
Bjornholm, M.1
Kawano, Y.2
Lehtihet, M.3
Zierath, J.R.4
-
45
-
-
0027930399
-
Genetic variants in the promoters and coding regions of muscle glycogen synthase and the inulin-responsive GLUT4 genes in NIDDM
-
Bjørbæk C, Echwald SM, Hubricht P et al.: Genetic variants in the promoters and coding regions of muscle glycogen synthase and the inulin-responsive GLUT4 genes in NIDDM. Diabetes 43: 976-983, 1994.
-
(1994)
Diabetes
, vol.43
, pp. 976-983
-
-
Bjørbæk, C.1
Echwald, S.M.2
Hubricht, P.3
-
46
-
-
0028804624
-
Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene and analysis of coding regions and mRNA levels of the ISPK-1 and the protein phosphatase-1 genes in muscle from NIDDM patients
-
Bjørbæk C, Vik TA, Echwald SM et al.: Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene and analysis of coding regions and mRNA levels of the ISPK-1 and the protein phosphatase-1 genes in muscle from NIDDM patients. Diabetes 44: 90-97, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 90-97
-
-
Bjørbæk, C.1
Vik, T.A.2
Echwald, S.M.3
-
47
-
-
0035119823
-
Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects
-
del Bosque-Plata L, Lin J, Horikawa Y, Schwarz PE, Cox NJ, Iwasaki N, Ogata M, Iwamoto Y, German MS, Bell GI: Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects. Diabetes 50: 694-696, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 694-696
-
-
Del Bosque-Plata, L.1
Lin, J.2
Horikawa, Y.3
Schwarz, P.E.4
Cox, N.J.5
Iwasaki, N.6
Ogata, M.7
Iwamoto, Y.8
German, M.S.9
Bell, G.I.10
-
48
-
-
0030721534
-
The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes
-
Brady MJ, Nairn AC, Saltiel AR: The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. J. Biol. Chem. 272: 29698-29703, 1997a.
-
(1997)
J Biol Chem
, vol.272
, pp. 29698-29703
-
-
Brady, M.J.1
Nairn, A.C.2
Saltiel, A.R.3
-
49
-
-
0030806934
-
Role of protein targeting to glycogen (PTG) in the regulation of protein phosphatase-1 activity
-
Brady MJ, Printen JA, Mastick CC, Saltiel AR: Role of protein targeting to glycogen (PTG) in the regulation of protein phosphatase-1 activity. J. Biol. Chem. 272: 20198-20204, 1997b.
-
(1997)
J Biol Chem
, vol.272
, pp. 20198-20204
-
-
Brady, M.J.1
Printen, J.A.2
Mastick, C.C.3
Saltiel, A.R.4
-
50
-
-
0035800763
-
Two splice variants of PKBgamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site Ser472 in the C-terminal hydrophobic domain
-
May 31
-
Brodbeck D, Hill MM, Hemmings BA: Two splice variants of PKBgamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site Ser472 in the C-terminal hydrophobic domain. J Biol Chem May 31, 2001.
-
(2001)
J Biol Chem
-
-
Brodbeck, D.1
Hill, M.M.2
Hemmings, B.A.3
-
51
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for 1R and IRS-1 null alleles
-
Brüning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR: Development of a novel polygenic model of NIDDM in mice heterozygous for 1R and IRS-1 null alleles. Cell 88: 561-572, 1997.
-
(1997)
Cell
, vol.88
, pp. 561-572
-
-
Brüning, J.C.1
Winnay, J.2
Bonner-Weir, S.3
Taylor, S.I.4
Accili, D.5
Kahn, C.R.6
-
52
-
-
0032214652
-
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
-
Brüning JC, Michael MD, Winnay JN, Hayashi T, Horsch D, Accili D, Goodyear LJ, Kahn CR: A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Moll Cell 2: 559-69, 1998.
-
(1998)
Moll Cell
, vol.2
, pp. 559-569
-
-
Brüning, J.C.1
Michael, M.D.2
Winnay, J.N.3
Hayashi, T.4
Horsch, D.5
Accili, D.6
Goodyear, L.J.7
Kahn, C.R.8
-
53
-
-
0034703229
-
Role of insulin receptor in control of body weight and reproduction
-
Brüning JC, gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, Klein R, Krone W, Müller-Wieland D, Kahn CR: Role of insulin receptor in control of body weight and reproduction. Science 289: 2122-25, 2000.
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Brüning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
Klein, R.7
Krone, W.8
Müller-Wieland, D.9
Kahn, C.R.10
-
54
-
-
15444347628
-
The Trp64 Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort
-
Buettner R, Schaffler A, Arndt H, Rogler G, Nusser J, Zietz B, Enger I, Hugl S, Cuk A, Scholmerich J, Palitzsch KD: The Trp64 Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort. J Clin Endocrinol Metab 83: 2892-7, 1998.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 2892-2897
-
-
Buettner, R.1
Schaffler, A.2
Arndt, H.3
Rogler, G.4
Nusser, J.5
Zietz, B.6
Enger, I.7
Hugl, S.8
Cuk, A.9
Scholmerich, J.10
Palitzsch, K.D.11
-
55
-
-
0034028904
-
Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis
-
Bulman MP, Kusumi K, frayling TM, McKeown C, Garrett C, Lander ES, Krumlauf R, Hattersley AT, Ellard S, Turnpenny PD: Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nature Genetics 24: 438-41, 2000.
-
(2000)
Nature Genetics
, vol.24
, pp. 438-441
-
-
Bulman, M.P.1
Kusumi, K.2
Frayling, T.M.3
McKeown, C.4
Garrett, C.5
Lander, E.S.6
Krumlauf, R.7
Hattersley, A.T.8
Ellard, S.9
Turnpenny, P.D.10
-
56
-
-
0023222361
-
Insulin receptor kinase in human skeletal muscle from obese subjects with and without non-insulin dependent diabetes
-
Caro JF, Sinha MK, Raju SM, Ittoop O, Pories WJ, Flickinger EG, Meelheim D, Dohm GL: Insulin receptor kinase in human skeletal muscle from obese subjects with and without non-insulin dependent diabetes. J Clin Invest 79: 1330-37, 1987.
-
(1987)
J Clin Invest
, vol.79
, pp. 1330-1337
-
-
Caro, J.F.1
Sinha, M.K.2
Raju, S.M.3
Ittoop, O.4
Pories, W.J.5
Flickinger, E.G.6
Meelheim, D.7
Dohm, G.L.8
-
57
-
-
0032881288
-
AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide dependent phosphorylation
-
Chan OT, Rittenhause SE, Tsichlis PN: AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide dependent phosphorylation. Ann. Rev. Biochem. 68: 965-1014, 1999.
-
(1999)
Ann Rev Biochem
, vol.68
, pp. 965-1014
-
-
Chan, O.T.1
Rittenhause, S.E.2
Tsichlis, P.N.3
-
58
-
-
0028904053
-
Insulin action and the insulin signaling network
-
Cheatham B, Kahn CR: Insulin action and the insulin signaling network. Endocrine Reviews 16; 2: 117-142, 1995.
-
(1995)
Endocrine Reviews
, vol.16
, Issue.2
, pp. 117-142
-
-
Cheatham, B.1
Kahn, C.R.2
-
59
-
-
0028039132
-
Sequence of the Human Glycogen-Associated Regulatory Subunit of Type 1 Protein Phosphatase and Analysis of its Coding Region and mRNA Level in Muscle from Patients with Non-Insulin-Dependent Diabetes Mellitus
-
Chen YH, Hansen L, Chen MW, Bjørbæk C, Vestergaard H, Hansen T, Cohen PTW, Pedersen O: Sequence of the Human Glycogen-Associated Regulatory Subunit of Type 1 Protein Phosphatase and Analysis of its Coding Region and mRNA Level in Muscle from Patients with Non-Insulin-Dependent Diabetes Mellitus. Diabetes 43: 1234-1241, 1994.
-
(1994)
Diabetes
, vol.43
, pp. 1234-1241
-
-
Chen, Y.H.1
Hansen, L.2
Chen, M.W.3
Bjørbæk, C.4
Vestergaard, H.5
Hansen, T.6
Cohen, P.T.W.7
Pedersen, O.8
-
60
-
-
0026667730
-
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
-
Cheng JQ, Godwin AK, Bellacosa A, Taguchi T, Franke TF, Hamilton TC, Tsichlis PN, Testa JR: AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. Proc. Natl. Acad. Sci. 89: 9267-9271, 1992.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 9267-9271
-
-
Cheng, J.Q.1
Godwin, A.K.2
Bellacosa, A.3
Taguchi, T.4
Franke, T.F.5
Hamilton, T.C.6
Tsichlis, P.N.7
Testa, J.R.8
-
61
-
-
0035368548
-
Insulin resistance and a diabetes-like syndrome in mice lacking the protein kinase akt2 (PKBb)
-
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB III, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ: Insulin resistance and a diabetes-like syndrome in mice lacking the protein kinase akt2 (PKBb). Science 292: 1728-1731, 2001.
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw III, E.B.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
62
-
-
0029882911
-
Promotor variation in the liver glucokinase is a risk for non-insulin-dependent diabetes mellitus
-
Chiu KC, McCarthy JE: Promotor variation in the liver glucokinase is a risk for non-insulin-dependent diabetes mellitus. Biochem Biophys Res Commun 221: 614-18, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 614-618
-
-
Chiu, K.C.1
McCarthy, J.E.2
-
63
-
-
0030828826
-
Preliminary data on a genome search in NIDDM siblings: The NIDDM1 locus on chromosome 2 is not linked to NIDDM in the Sardinian population
-
Study group for the genetics of diabetes in Sardenia
-
Ciccarese M, Tonolo G, Delin I, Wong FK, Holm P, Atzeni MM, Lichtenstein P, Kockum I, Maioli M, Luthman H: Preliminary data on a genome search in NIDDM siblings: the NIDDM1 locus on chromosome 2 is not linked to NIDDM in the Sardinian population. Study group for the genetics of diabetes in Sardenia. Diabetologia 40: 1366-67, 1997.
-
(1997)
Diabetologia
, vol.40
, pp. 1366-1367
-
-
Ciccarese, M.1
Tonolo, G.2
Delin, I.3
Wong, F.K.4
Holm, P.5
Atzeni, M.M.6
Lichtenstein, P.7
Kockum, I.8
Maioli, M.9
Luthman, H.10
-
64
-
-
0029118510
-
Insulin resistance: Interactions between a common variant of the insulin receptor substrate-1
-
Clausen JO, Hansen T, Bjørbæk C, Echwald SM, Urhammer SA, Rasmussen SB, Andersen CB, Hansen L, Almind K, Winther K, Haraldsdȯttir J, Borch-Johnsen K, Pedersen O: Insulin resistance: Interactions between a common variant of the insulin receptor substrate-1. Lancet 346: 397-402, 1995.
-
(1995)
Lancet
, vol.346
, pp. 397-402
-
-
Clausen, J.O.1
Hansen, T.2
Bjørbæk, C.3
Echwald, S.M.4
Urhammer, S.A.5
Rasmussen, S.B.6
Andersen, C.B.7
Hansen, L.8
Almind, K.9
Winther, K.10
Haraldsdottir, J.11
Borch-Johnsen, K.12
Pedersen, O.13
-
65
-
-
0029775612
-
Insulin sensitivity index, acute insulin response and glucose effectiveness in a population-based sample of 380 young healthy caucasians
-
Clausen JO, Borch-Johnsen K, Ibsen H, Bergman RN, Hougaard P, Winther K, Pedersen O Insulin sensitivity index, acute insulin response and glucose effectiveness in a population-based sample of 380 young healthy caucasians. J Clin Invest 98: 1195-1209, 1996.
-
(1996)
J Clin Invest
, vol.98
, pp. 1195-1209
-
-
Clausen, J.O.1
Borch-Johnsen, K.2
Ibsen, H.3
Bergman, R.N.4
Hougaard, P.5
Winther, K.6
Pedersen, O.7
-
66
-
-
0030996141
-
ATP Channel Subunits
-
ATP Channel Subunits. Neuron 18: 827-838, 1997.
-
(1997)
Neuron
, vol.18
, pp. 827-838
-
-
Clement IV, J.P.1
Kunjilwar, K.2
Gonzalez, G.3
Schwanstecher, M.4
Panten, U.5
Aguilar-Bryan, L.6
Bryan, J.7
-
67
-
-
0344019486
-
A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: Indication for linkage with islet 1 locus on chromosome 5q
-
Clement K, Dina C, Basdevant A, Chastang N, Pellouc V, Lahlou N, Berlan M, Langin D, Guy-Grand B, Froguel P: A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q. Diabetes 48: 398-402, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 398-402
-
-
Clement, K.1
Dina, C.2
Basdevant, A.3
Chastang, N.4
Pellouc, V.5
Lahlou, N.6
Berlan, M.7
Langin, D.8
Guy-Grand, B.9
Froguel, P.10
-
68
-
-
0004509649
-
The Pro115Gln and the Pro12Ala PPAR-g gene mutations in obesity and type 2 diabetes
-
Clement K, Hercberg S, Passinge B, Galan P, Varroud-Vial M, Schuldiner AR, Beamer BA, Charpentier G, Guy-Grand B, Froguel P, Vaisse C: The Pro115Gln and the Pro12Ala PPAR-g gene mutations in obesity and type 2 diabetes. Int J Obes Relat Metab Disord 24: 391-393, 2000.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 391-393
-
-
Clement, K.1
Hercberg, S.2
Passinge, B.3
Galan, P.4
Varroud-Vial, M.5
Schuldiner, A.R.6
Beamer, B.A.7
Charpentier, G.8
Guy-Grand, B.9
Froguel, P.10
Vaisse, C.11
-
69
-
-
77956911584
-
Muscle glycogen synthase
-
Cohen P: Muscle glycogen synthase. The Enzymes. vol. XVII: 461-497,1986
-
(1986)
The Enzymes
, vol.17
, pp. 461-497
-
-
Cohen, P.1
-
70
-
-
0030841793
-
PDK1, one of the missing links in insulin signal transduction?
-
Cohen P, Alesssi DR, Cross DA: PDK1, one of the missing links in insulin signal transduction? FEBS Lett. 410: 3-10, 1997.
-
(1997)
FEBS Lett
, vol.410
, pp. 3-10
-
-
Cohen, P.1
Alesssi, D.R.2
Cross, D.A.3
-
71
-
-
0034076458
-
The Pro12Ala variant of peroxisome proliferator-activated receptor-2γ (PPAR-2γ) is associated with measures of obesity in Mexican Americans
-
Cole SA, Mitchell BD, Hsueh WC, Pineda P, Bearner BA, Shuldiner AR, Comuzzie AG, Blangero J, Hixson JE: The Pro12Ala variant of peroxisome proliferator-activated receptor-2γ (PPAR-2γ) is associated with measures of obesity in Mexican Americans. Int J Obes Relat Metab Disord 24: 522-24, 2000.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 522-524
-
-
Cole, S.A.1
Mitchell, B.D.2
Hsueh, W.C.3
Pineda, P.4
Bearner, B.A.5
Shuldiner, A.R.6
Comuzzie, A.G.7
Blangero, J.8
Hixson, J.E.9
-
72
-
-
0030734345
-
Physiological role of Akt in insulin-stimulated translocation of Glut4 in transfected rat adipose cells
-
Cong L, Chen H, Zhou L, McGibbon MA, Taylot SI, Qoun MJ: Physiological role of Akt in insulin-stimulated translocation of Glut4 in transfected rat adipose cells. Mol. Endcrinol. 11: 1881-1890, 1997.
-
(1997)
Mol Endcrinol
, vol.11
, pp. 1881-1890
-
-
Cong, L.1
Chen, H.2
Zhou, L.3
McGibbon, M.A.4
Taylot, S.I.5
Qoun, M.J.6
-
73
-
-
0027476081
-
Association of low birth weight with β-cell function in the adult first degree relaitves of non-insulin-dependent diabetes subject
-
Cook JTE, Levy JC, Page RCL, Shaw JAG, Hattersley AT, Turner RC: Association of low birth weight with β-cell function in the adult first degree relaitves of non-insulin-dependent diabetes subject. BMJ 306: 302-6, 1993.
-
(1993)
BMJ
, vol.306
, pp. 302-306
-
-
Cook, J.T.E.1
Levy, J.C.2
Page, R.C.L.3
Shaw, J.A.G.4
Hattersley, A.T.5
Turner, R.C.6
-
74
-
-
0032928542
-
Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans
-
Cox NJ, Frigge M, Nicolae DL, Concannon P, Hanis CL, Bell GI, Kong A: Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans. Nature Gen. 21: 213-215, 1999.
-
(1999)
Nature Gen
, vol.21
, pp. 213-215
-
-
Cox, N.J.1
Frigge, M.2
Nicolae, D.L.3
Concannon, P.4
Hanis, C.L.5
Bell, G.I.6
Kong, A.7
-
75
-
-
0034821661
-
Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families
-
Cox NJ, Wapelhorst B, Morrison VA, Johnson L, Pinchuk L, Spielman RS, Todd JA, Concannon P: Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet 69 (August), 2001.
-
(2001)
Am J Hum Genet
, vol.69
, Issue.AUGUST
-
-
Cox, N.J.1
Wapelhorst, B.2
Morrison, V.A.3
Johnson, L.4
Pinchuk, L.5
Spielman, R.S.6
Todd, J.A.7
Concannon, P.8
-
76
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DAE, Alessi DR, Cohen P, Andjelkovich M, Hemmings B: Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789, 1995.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.E.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.5
-
77
-
-
0033054726
-
Intermediate expansions of a GAA repeat in the frataxin gene are nor associated with type 2 diabetes or altered glucose-induced beta-cell function in Danish Caucasians
-
Dalgaard LT, Hansen T, Urhammer SA, Clausen JO, Eiberg H, Pedersen O: Intermediate expansions of a GAA repeat in the frataxin gene are nor associated with type 2 diabetes or altered glucose-induced beta-cell function in Danish Caucasians. Diabetes 48: 914-917, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 914-917
-
-
Dalgaard, L.T.1
Hansen, T.2
Urhammer, S.A.3
Clausen, J.O.4
Eiberg, H.5
Pedersen, O.6
-
78
-
-
0025860114
-
Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus
-
Damsbo P, Vaag A, Hother-Nielsen O, Beck-Nielsen H: Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34: 239-45, 1991.
-
(1991)
Diabetologia
, vol.34
, pp. 239-245
-
-
Damsbo, P.1
Vaag, A.2
Hother-Nielsen, O.3
Beck-Nielsen, H.4
-
79
-
-
0031595923
-
A Pro12Ala substitution in PPAR-2γ associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, kuusisto J, Laakso M, Fujimoto W, Auwerx J: A Pro12Ala substitution in PPAR-2γ associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 20: 284-87, 1998.
-
(1998)
Nat Genet
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykkanen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
80
-
-
0018520840
-
Glucose clamp technique: A method for quantifying insulin secretion and resistance
-
DeFronzo RA, Tobin JD, Andres R: Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237: E214-E223, 1979.
-
(1979)
Am J Physiol
, vol.237
-
-
DeFronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
81
-
-
0025522071
-
The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
-
Dent P, Lavoinnne A, Nakielny S, Caudwell FB, Watt P, Cohen P: The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle. Nature 348: 302-308, 1990.
-
(1990)
Nature
, vol.348
, pp. 302-308
-
-
Dent, P.1
Lavoinnne, A.2
Nakielny, S.3
Caudwell, F.B.4
Watt, P.5
Cohen, P.6
-
82
-
-
0028157767
-
PI 3-kinase: Structural and functional analysis of intersubunit interactions
-
Dhand R, Hara K, Hiles I, Bax B, Gout I, Panayotou G, Fry MJ, Yonezawa K, Kasuga M, Waterfield MD: PI 3-kinase: structural and functional analysis of intersubunit interactions. EMBO J. 13: 511-21, 1994.
-
(1994)
EMBO J
, vol.13
, pp. 511-521
-
-
Dhand, R.1
Hara, K.2
Hiles, I.3
Bax, B.4
Gout, I.5
Panayotou, G.6
Fry, M.J.7
Yonezawa, K.8
Kasuga, M.9
Waterfield, M.D.10
-
83
-
-
0030590869
-
Amino acid sequence of a novel protein phophatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phophatase 1
-
Doherty M, Young PR, Cohen PTW: Amino acid sequence of a novel protein phophatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phophatase 1. FEBS Lett. 399: 339-343, 1996.
-
(1996)
FEBS Lett
, vol.399
, pp. 339-343
-
-
Doherty, M.1
Young, P.R.2
Cohen, P.T.W.3
-
84
-
-
0035029812
-
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes
-
Ducluzeau PH, Perretti N, Laville M, Andreelli F, Vega N, Riou JP, Vidal H: Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes 50: 1134-42, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 1134-1142
-
-
Ducluzeau, P.H.1
Perretti, N.2
Laville, M.3
Andreelli, F.4
Vega, N.5
Riou, J.P.6
Vidal, H.7
-
85
-
-
0033365057
-
Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans
-
Duggirala R, Blangero J, Almasy L, Dyer TD, Williams KL, Leach RJ, O'Connell P, Stern MP: Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Gen 64: 1127-1140, 1999.
-
(1999)
Am J Hum Gen
, vol.64
, pp. 1127-1140
-
-
Duggirala, R.1
Blangero, J.2
Almasy, L.3
Dyer, T.D.4
Williams, K.L.5
Leach, R.J.6
O'Connell, P.7
Stern, M.P.8
-
86
-
-
0033051861
-
No evidence of linkage or diabetes-associated mutations in the transcription factors Beta2/NeuroD1 and Pax4 in type 2 diabetes in France
-
Dupont S, Vionnet N, Chevre JC, Gallina S, Dina C, Seino Y, Yamada Y, Froguel P: No evidence of linkage or diabetes-associated mutations in the transcription factors Beta2/NeuroD1 and Pax4 in type 2 diabetes in France. Diabetologia 42: 480-484, 1999.
-
(1999)
Diabetologia
, vol.42
, pp. 480-484
-
-
Dupont, S.1
Vionnet, N.2
Chevre, J.C.3
Gallina, S.4
Dina, C.5
Seino, Y.6
Yamada, Y.7
Froguel, P.8
-
87
-
-
0033431661
-
Absence of replication in the French population of the association between beta 2/NEUROD-A 45T polymorphism and type 1 diabetes
-
Dupont S, Dina C, Hani EH, Froguel P: Absence of replication in the French population of the association between beta 2/NEUROD-A45T polymorphism and type 1 diabetes. Diabetes Metab 25: 516-17, 1999.
-
(1999)
Diabetes Metab
, vol.25
, pp. 516-517
-
-
Dupont, S.1
Dina, C.2
Hani, E.H.3
Froguel, P.4
-
88
-
-
0028962835
-
Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness and insulin sensitivity
-
Echwald SM, Bjoerbaek C, Hansen T, Clausen JO, Vestergaard H, Zierath JR, Printz RL, Granner DK, Pedersen O: Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness and insulin sensitivity. Diabetes 44: 347-353, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 347-353
-
-
Echwald, S.M.1
Bjoerbaek, C.2
Hansen, T.3
Clausen, J.O.4
Vestergaard, H.5
Zierath, J.R.6
Printz, R.L.7
Granner, D.K.8
Pedersen, O.9
-
89
-
-
0033553415
-
Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance
-
Egawa K, Sharma PM, Nakashima N, Huang Y, Huver E, Boss GR, Olefsky JM: Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance. J Biol Chem 274: 14306-14, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 14306-14314
-
-
Egawa, K.1
Sharma, P.M.2
Nakashima, N.3
Huang, Y.4
Huver, E.5
Boss, G.R.6
Olefsky, J.M.7
-
90
-
-
0033942075
-
Genome-wide search for type 2 diabetes susceptibility genes in four American populations
-
Ehm MG, Karnoub MC, Sakul H, Gottschalk K, Holt DC, Weber JL, Vaske D, Briley D, Briley L, Kopf J, McMillen P, Nguyen Q, Reisman M, Lai EH, Joslyn G, Shepherd NS, Bell C, Wagner MJ, Burns DK: Genome-wide search for type 2 diabetes susceptibility genes in four American populations. Am J Hum Genet 66: 1871-81, 2000.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1871-1881
-
-
Ehm, M.G.1
Karnoub, M.C.2
Sakul, H.3
Gottschalk, K.4
Holt, D.C.5
Weber, J.L.6
Vaske, D.7
Briley, D.8
Briley, L.9
Kopf, J.10
McMillen, P.11
Nguyen, Q.12
Reisman, M.13
Lai, E.H.14
Joslyn, G.15
Shepherd, N.S.16
Bell, C.17
Wagner, M.J.18
Burns, D.K.19
-
91
-
-
0032781890
-
Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated activated receptor-g2 (PPAR-g2): Divergent modulating effects on body mass index in obese and lean Caucasian men
-
Ek J, Urhammer SA, Sorensen TI, Andersen T, Auwerx J, Pedersen O: Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated activated receptor-g2 (PPAR-g2): divergent modulating effects on body mass index in obese and lean Caucasian men. Diabetologia 42: 892-95, 1999.
-
(1999)
Diabetologia
, vol.42
, pp. 892-895
-
-
Ek, J.1
Urhammer, S.A.2
Sorensen, T.I.3
Andersen, T.4
Auwerx, J.5
Pedersen, O.6
-
92
-
-
0026664599
-
Linkage analysis of insulin-receptor gene in familial NIDDM
-
Elbein SC, Sorensen LK, Taylor M: Linkage analysis of insulin-receptor gene in familial NIDDM. Diabetes 41: 648-56, 1992.
-
(1992)
Diabetes
, vol.41
, pp. 648-656
-
-
Elbein, S.C.1
Sorensen, L.K.2
Taylor, M.3
-
93
-
-
0027446952
-
Methionine for valine substitution in exon 17 of the insulin receptor gene in a pedigree with familial NIDDM
-
Elbein SC, Sorensen LK, Schumacher MC Methionine for valine substitution in exon 17 of the insulin receptor gene in a pedigree with familial NIDDM. Diabetes 42: 429-434, 1993.
-
(1993)
Diabetes
, vol.42
, pp. 429-434
-
-
Elbein, S.C.1
Sorensen, L.K.2
Schumacher, M.C.3
-
94
-
-
0029976297
-
Role of mitochondrial DNA tRNA leucine nd glucagon receptor missense muations in Utah white diabetic patients
-
Elbein SC, Hoffman MD: Role of mitochondrial DNA tRNA leucine nd glucagon receptor missense muations in Utah white diabetic patients. Diabetes Care 19: 507-8, 1996.
-
(1996)
Diabetes Care
, vol.19
, pp. 507-508
-
-
Elbein, S.C.1
Hoffman, M.D.2
-
95
-
-
0033312608
-
Heritability of pancdraetic β-cell function among nondiabetic members of Caucasian familial type 2 diabetic kindreds
-
Elbein SC, Hasstedt SJ, Wegner K, Kahn SE: Heritability of pancdraetic β-cell function among nondiabetic members of Caucasian familial type 2 diabetic kindreds. J Clin Endocrinol Metab 84: 1398-403, 1999.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 1398-1403
-
-
Elbein, S.C.1
Hasstedt, S.J.2
Wegner, K.3
Kahn, S.E.4
-
96
-
-
0032910599
-
A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians
-
Elbein SC, Hoffman MD, Teng K, Leppert MF, Hasstedt SJ: A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians. Diabetes 48: 1175-82, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1175-1182
-
-
Elbein, S.C.1
Hoffman, M.D.2
Teng, K.3
Leppert, M.F.4
Hasstedt, S.J.5
-
97
-
-
0029811140
-
Expression of glycogen synthase kinase-3 mutants in cells and their effects on glycogen synthase activity in intact cells
-
Eldar-Finkelman H, Argast GM, Foord O, Fisher E, Krebs EG: Expression of glycogen synthase kinase-3 mutants in cells and their effects on glycogen synthase activity in intact cells. Proc. Natl. Acad. Sci. USA. 93: 10228-10233, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10228-10233
-
-
Eldar-Finkelman, H.1
Argast, G.M.2
Foord, O.3
Fisher, E.4
Krebs, E.G.5
-
98
-
-
0029870187
-
Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase inhibitor
-
Endo S, Zhou X, Connor J, Wang B, Shenolikar S: Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase inhibitor. Biochemistry 35: 5220-5228, 1996.
-
(1996)
Biochemistry
, vol.35
, pp. 5220-5228
-
-
Endo, S.1
Zhou, X.2
Connor, J.3
Wang, B.4
Shenolikar, S.5
-
99
-
-
0033548138
-
Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion
-
Eto K, Tsubamoto Y, Terauchi Y, Sugiyama T, Kishimoto T, Takahashi N, Yamauchi N, Kubota N, Murayama S, Aizawa T, Akanuma Y, Aizawa S, Kasai H, Yazaki Y, Kadowaki T: Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion. Science 283: 981-985, 1999.
-
(1999)
Science
, vol.283
, pp. 981-985
-
-
Eto, K.1
Tsubamoto, Y.2
Terauchi, Y.3
Sugiyama, T.4
Kishimoto, T.5
Takahashi, N.6
Yamauchi, N.7
Kubota, N.8
Murayama, S.9
Aizawa, T.10
Akanuma, Y.11
Aizawa, S.12
Kasai, H.13
Yazaki, Y.14
Kadowaki, T.15
-
100
-
-
0034894047
-
Studies of Association between the Gene for Calpain-10 and Type 2 Diabetes Mellitus in the United Kingdom
-
Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT: Studies of Association between the Gene for Calpain-10 and Type 2 Diabetes Mellitus in the United Kingdom. Am J Hum Genet 69: 544-52, 2001.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 544-552
-
-
Evans, J.C.1
Frayling, T.M.2
Cassell, P.G.3
Saker, P.J.4
Hitman, G.A.5
Walker, M.6
Levy, J.C.7
O'Rahilly, S.8
Rao, P.V.9
Bennett, A.J.10
Jones, E.C.11
Menzel, S.12
Prestwich, P.13
Simecek, N.14
Wishart, M.15
Dhillon, R.16
Fletcher, C.17
Millward, A.18
Demaine, A.19
Wilkin, T.20
Horikawa, Y.21
Cox, N.J.22
Bell, G.I.23
Ellard, S.24
McCarthy, M.I.25
Hattersley, A.T.26
more..
-
101
-
-
0035220244
-
The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets
-
Federici M, Hribal ML, Ranalli M, Marselli L, Porzio O, Lauro D, Borboni P, Lauro R, Marchetti P, Melino G, Sesti G: The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets. Faseb J 15: 22-24, 2001.
-
(2001)
FASEB J
, vol.15
, pp. 22-24
-
-
Federici, M.1
Hribal, M.L.2
Ranalli, M.3
Marselli, L.4
Porzio, O.5
Lauro, D.6
Borboni, P.7
Lauro, R.8
Marchetti, P.9
Melino, G.10
Sesti, G.11
-
102
-
-
0027230143
-
Insulin-mediated pseudoacromegaly: Clinical and biochemical characterization of a syndrome of selective insulin resistance
-
Flier JS, Moller DE, Moses AC, O'Rahilly S, Chaiken R, Grigorescu F, Kahn BB, Weinreb JE, Eastman R Insulin-mediated pseudoacromegaly: Clinical and biochemical characterization of a syndrome of selective insulin resistance. J Clin Endocrinol Metab 76: 1533-1541, 1993.
-
(1993)
J Clin Endocrinol Metab
, vol.76
, pp. 1533-1541
-
-
Flier, J.S.1
Moller, D.E.2
Moses, A.C.3
O'Rahilly, S.4
Chaiken, R.5
Grigorescu, F.6
Kahn, B.B.7
Weinreb, J.E.8
Eastman, R.9
-
103
-
-
17744371120
-
No evidence for linkage at candidate type 2 diabetes susceptibility loci on chromosomes 12 and 20 in United kingdom Caucasians
-
Frayling TM, McCarthy MI, walker M, Levy JC, O'Rahilly S, Hitman GA, Rao PV, Bennet A J, Jones EC, Menzel S, Ellard S, Hattersley AT: No evidence for linkage at candidate type 2 diabetes susceptibility loci on chromosomes 12 and 20 in United kingdom Caucasians. J Clin Endocrin Metab 85: 853-57, 2000.
-
(2000)
J Clin Endocrin Metab
, vol.85
, pp. 853-857
-
-
Frayling, T.M.1
McCarthy, M.I.2
Walker, M.3
Levy, J.C.4
O'Rahilly, S.5
Hitman, G.A.6
Rao, P.V.7
Bennet, A.J.8
Jones, E.C.9
Menzel, S.10
Ellard, S.11
Hattersley, A.T.12
-
104
-
-
0030991386
-
High affinity binding of inositol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on kinase activity
-
Frech M, Andjelkovic M, Ingley E, Reddy KK, Falck JR, Hemmings BA: High affinity binding of inositol phosphates and phosphoinositides to the pleckstrin homology domain of RAC/protein kinase B and their influence on kinase activity. J Biol Chem 272: 8374-81, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 8374-8381
-
-
Frech, M.1
Andjelkovic, M.2
Ingley, E.3
Reddy, K.K.4
Falck, J.R.5
Hemmings, B.A.6
-
105
-
-
0027472126
-
Familial hyperglycemia due to mutations in the glucokinase: Definition of a subtype of diabetes mellitus
-
Froguel P, Zouali H, Vionnet N, Velho G, Vaxiliaire M, Sun F, Lesage S, Stoffel M, Takeda J, Passa P: Familial hyperglycemia due to mutations in the glucokinase: definition of a subtype of diabetes mellitus. N Engl J Med 328: 697-702, 1993.
-
(1993)
N Engl J Med
, vol.328
, pp. 697-702
-
-
Froguel, P.1
Zouali, H.2
Vionnet, N.3
Velho, G.4
Vaxiliaire, M.5
Sun, F.6
Lesage, S.7
Stoffel, M.8
Takeda, J.9
Passa, P.10
-
106
-
-
0033757592
-
Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha
-
Fruman DA, Mauvais-Jarvis F, Pollard DA, Yballe CM, Brazil D, Bronson RT, Kahn CR, Cantley LC: Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha. Nature Genetics 26: 379-82, 2000.
-
(2000)
Nature Genetics
, vol.26
, pp. 379-382
-
-
Fruman, D.A.1
Mauvais-Jarvis, F.2
Pollard, D.A.3
Yballe, C.M.4
Brazil, D.5
Bronson, R.T.6
Kahn, C.R.7
Cantley, L.C.8
-
107
-
-
0029098051
-
A mutation in the glucagon receptor gene (Gly40Ser): Heterogenity in the association with diabetes mellitus
-
Fujisawa T, Ikegami H, Yamoto E, Takekawa Y, Hamada Y, Ueda H, Fukuda M, Ogihara T: A mutation in the glucagon receptor gene (Gly40Ser): heterogenity in the association with diabetes mellitus. Diabetologia 38: 983-85, 1995.
-
(1995)
Diabetologia
, vol.38
, pp. 983-985
-
-
Fujisawa, T.1
Ikegami, H.2
Yamoto, E.3
Takekawa, Y.4
Hamada, Y.5
Ueda, H.6
Fukuda, M.7
Ogihara, T.8
-
108
-
-
0031874185
-
Mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese
-
Furuta H, Horikawa Y, Iwasaki N et al. Mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese. Diabetes 47: 1356-1358, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 1356-1358
-
-
Furuta, H.1
Horikawa, Y.2
Iwasaki, N.3
-
109
-
-
0030058877
-
Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat
-
Galli J, Li L-S, Glaser A, Östenson C-G, Jiao H, Fakhrai-Rad H, Jacob HJ, Lander ES, Luthman H: Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat. Nat Genet 12: 31-37, 1996.
-
(1996)
Nat Genet
, vol.12
, pp. 31-37
-
-
Galli, J.1
Li, L.-S.2
Glaser, A.3
Östenson, C.-G.4
Jiao, H.5
Fakhrai-Rad, H.6
Jacob, H.J.7
Lander, E.S.8
Luthman, H.9
-
110
-
-
0033506255
-
Pathophysiological and genetic characterization of the major diabetes locus in GK rats
-
Galli J, Fakhrai-Rad H, Kamel A, Marcus C, Norgren S, Luthman H: Pathophysiological and genetic characterization of the major diabetes locus in GK rats. Diabetes 48: 2463-70, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 2463-2470
-
-
Galli, J.1
Fakhrai-Rad, H.2
Kamel, A.3
Marcus, C.4
Norgren, S.5
Luthman, H.6
-
111
-
-
9044247460
-
Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat
-
Gaugier D, Froguel P, Parent V, Bernard C, Bihoreau M-T, Portha B, James MR, Penicaud L, Lathrop M, Ktorza A: Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nat Genet 12: 38-43, 1996.
-
(1996)
Nat Genet
, vol.12
, pp. 38-43
-
-
Gaugier, D.1
Froguel, P.2
Parent, V.3
Bernard, C.4
Bihoreau, M.-T.5
Portha, B.6
James, M.R.7
Penicaud, L.8
Lathrop, M.9
Ktorza, A.10
-
112
-
-
17644441297
-
A large sample of Finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter
-
Ghosh S, Hauser ER, Magnuson VL, Valle T, Ally DS, Karanjawala ZE, Rayman JB, Knapp J, Musick A, Tannenbaum J, Te C, Eldridge W, Shapiro S, Musick T, Martin C, So A, Witt A, Blaschak Harvan J, Watanabe RM, hagopian W, Eriksson J, Nylund SJ, Kohtamaki K, Tuomilehto-Wolf E, Collins FS, Boehnke M: A large sample of Finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter. J Clin Invest 102: 704-9, 1998.
-
(1998)
J Clin Invest
, vol.102
, pp. 704-709
-
-
Ghosh, S.1
Hauser, E.R.2
Magnuson, V.L.3
Valle, T.4
Ally, D.S.5
Karanjawala, Z.E.6
Rayman, J.B.7
Knapp, J.8
Musick, A.9
Tannenbaum, J.10
Te, C.11
Eldridge, W.12
Shapiro, S.13
Musick, T.14
Martin, C.15
So, A.16
Witt, A.17
Blaschak Harvan, J.18
Watanabe, R.M.19
Hagopian, W.20
Eriksson, J.21
Nylund, S.J.22
Kohtamaki, K.23
Tuomilehto-Wolf, E.24
Collins, F.S.25
Boehnke, M.26
more..
-
113
-
-
13044277561
-
Type 2 diabetes: Evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs
-
Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, Erdos MR, Langefeld CD, Balow J Jr, Ally DS, Kohtamaki K, Chines P, Birznieks G, Kaleta HS, Musick A, Te C, Tannenbaum J, Eldridge W, Shapiro S, Martin C, Witt A, So A, Chang J, Shurtleff B, Porter R Boehnke M et al: Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci 96: 2198-203, 1999.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 2198-2203
-
-
Ghosh, S.1
Watanabe, R.M.2
Hauser, E.R.3
Valle, T.4
Magnuson, V.L.5
Erdos, M.R.6
Langefeld, C.D.7
Balow Jr., J.8
Ally, D.S.9
Kohtamaki, K.10
Chines, P.11
Birznieks, G.12
Kaleta, H.S.13
Musick, A.14
Te, C.15
Tannenbaum, J.16
Eldridge, W.17
Shapiro, S.18
Martin, C.19
Witt, A.20
So, A.21
Chang, J.22
Shurtleff, B.23
Porter, R.24
Boehnke, M.25
more..
-
114
-
-
0032556969
-
Familial hyper-insulinism caused by an activating glucokinase mutation
-
Glaser B, Kesavan P, Heyman M, Davis E, Cuesta A, Buchs A, Stanley CA, Thornton PS, Permutt MA, Matschinsky FM, Herold KC: Familial hyper-insulinism caused by an activating glucokinase mutation. N Engl J Med 338: 226-30, 1998.
-
(1998)
N Engl J Med
, vol.338
, pp. 226-230
-
-
Glaser, B.1
Kesavan, P.2
Heyman, M.3
Davis, E.4
Cuesta, A.5
Buchs, A.6
Stanley, C.A.7
Thornton, P.S.8
Permutt, M.A.9
Matschinsky, F.M.10
Herold, K.C.11
-
115
-
-
0035043009
-
Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53)
-
Gloyn L, Hashim Y, Ashcroft SJ, Ashfield R, Wiltshire S, Turner RC: Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53). Diabetic Medicine 18: 206-10, 2001.
-
(2001)
Diabetic Medicine
, vol.18
, pp. 206-210
-
-
Gloyn, L.1
Hashim, Y.2
Ashcroft, S.J.3
Ashfield, R.4
Wiltshire, S.5
Turner, R.C.6
-
116
-
-
0028903232
-
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects
-
Goodyear LJ, Giorgino F, Sherman LA, Carey J, Smith RJ, Dohm GL: Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J Clin Invest 95: 2195-204, 1995.
-
(1995)
J Clin Invest
, vol.95
, pp. 2195-2204
-
-
Goodyear, L.J.1
Giorgino, F.2
Sherman, L.A.3
Carey, J.4
Smith, R.J.5
Dohm, G.L.6
-
117
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl G, Dierich A, Lemeur M, Guillemot F: Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Natl. Acad. Sci. U.S.A. 97: 1607-1611, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
Lemeur, M.3
Guillemot, F.4
-
118
-
-
0027511164
-
Association between polymorphism of the glycogen synthase gene and non-insulin dependent diabetes mellitus
-
Groop LC, Kankuri M, Shalin-Jantti C, Ekstrand A, Nikula-Ijas P, Widen E, Kuismanen E, Eriksson J, Franssila-Kallunki A, Saloranta C, et al: Association between polymorphism of the glycogen synthase gene and non-insulin dependent diabetes mellitus. New Engl J Med 328: 10-14, 1993.
-
(1993)
New Engl J Med
, vol.328
, pp. 10-14
-
-
Groop, L.C.1
Kankuri, M.2
Shalin-Jantti, C.3
Ekstrand, A.4
Nikula-Ijas, P.5
Widen, E.6
Kuismanen, E.7
Eriksson, J.8
Franssila-Kallunki, A.9
Saloranta, C.10
-
119
-
-
0033863689
-
Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis
-
Gu HF, Almgren P, Lindholm E, Frittitta L, Trischitta V, Groop LC: Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis. Diabetes: 49: 1601-3, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 1601-1603
-
-
Gu, H.F.1
Almgren, P.2
Lindholm, E.3
Frittitta, L.4
Trischitta, V.5
Groop, L.C.6
-
120
-
-
0028848010
-
A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus
-
Hager J, Hansen L, Vaisse C, Vionnet N, Philippi A, Poller W, Velho G, Carcassi C, Contu L, Juliet C, et al: A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus. Nat Genet 9: 299-304, 1995.
-
(1995)
Nat Genet
, vol.9
, pp. 299-304
-
-
Hager, J.1
Hansen, L.2
Vaisse, C.3
Vionnet, N.4
Philippi, A.5
Poller, W.6
Velho, G.7
Carcassi, C.8
Contu, L.9
Juliet, C.10
-
121
-
-
0026008824
-
Fetal and infant growth and impaired glucose tolerance at age 64
-
Hales CN, Barker DJ, Clark PM, Cox LJ, Fall C, Osmond C, Winther PD: Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 303: 259-62, 1991.
-
(1991)
BMJ
, vol.303
, pp. 259-262
-
-
Hales, C.N.1
Barker, D.J.2
Clark, P.M.3
Cox, L.J.4
Fall, C.5
Osmond, C.6
Winther, P.D.7
-
122
-
-
0026969347
-
Genetic and enviromental determinants of non-insulin dependent diabetes mellitus (NIDDM)
-
Hamman RF: Genetic and enviromental determinants of non-insulin dependent diabetes mellitus (NIDDM). Diabetes Metab Rev 8: 287-338, 1992.
-
(1992)
Diabetes Metab Rev
, vol.8
, pp. 287-338
-
-
Hamman, R.F.1
-
123
-
-
14444273653
-
Genetic studies of the sulphonylurea receptor gene in NIDDM and morbid obesity among French Caucasians
-
Hani EH, Clement K, Velho G, Vionnet N, Hager J, Philippi A, Dina C, Inoue H, Permutt MA, Basdevant A, North M, Demenais F, Guy-Grand B, Froguel P: Genetic studies of the sulphonylurea receptor gene iin NIDDM and morbid obesity among French Caucasians. Diabetes 46: 688-694,1997a.
-
(1997)
Diabetes
, vol.46
, pp. 688-694
-
-
Hani, E.H.1
Clement, K.2
Velho, G.3
Vionnet, N.4
Hager, J.5
Philippi, A.6
Dina, C.7
Inoue, H.8
Permutt, M.A.9
Basdevant, A.10
North, M.11
Demenais, F.12
Guy-Grand, B.13
Froguel, P.14
-
124
-
-
0030925094
-
Mapping NIDDM susceptibility loci in French families: Studies with markers in the region of NIDDM1 on chromosome 2q
-
Hani EH, Hager J, Philippi A, Demenais F, Froguel P, Vionnet N: Mapping NIDDM susceptibility loci in French families: studies with markers in the region of NIDDM1 on chromosome 2q. Diabetes 46: 1225-26, 1997b.
-
(1997)
Diabetes
, vol.46
, pp. 1225-1226
-
-
Hani, E.H.1
Hager, J.2
Philippi, A.3
Demenais, F.4
Froguel, P.5
Vionnet, N.6
-
125
-
-
0031773333
-
+ channel gene (KIR6.2/BIR): A meta-analysis suggests a role in the polygenic basis of type II diabetes mellitus in Caucasians
-
+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of type II diabetes mellitus in Caucasians. Diabotologia 41: 1511-5, 1998.
-
(1998)
Diabotologia
, vol.41
, pp. 1511-1515
-
-
Hani, E.H.1
Boutin, P.2
Durand, E.3
Inoue, H.4
Permutt, M.A.5
Velho, G.6
Froguel, P.7
-
126
-
-
0032718689
-
Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus
-
Hani EH, Stoffers DA, Chévre J-C, Durand E, Stanojevic V, Dina C, Habener JF, Froguel P: Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus. J Clin Invest 104: R41-48, 1999.
-
(1999)
J Clin Invest
, vol.104
-
-
Hani, E.H.1
Stoffers, D.A.2
Chévre, J.-C.3
Durand, E.4
Stanojevic, V.5
Dina, C.6
Habener, J.F.7
Froguel, P.8
-
127
-
-
9044243415
-
A geneome-wide search for Non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2
-
Hanis CL, Boerwinkel E, Chakraborty R et al.: A geneome-wide search for Non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nature Gen. 13; 2: 161-166, 1996.
-
(1996)
Nature Gen
, vol.13
, Issue.2
, pp. 161-166
-
-
Hanis, C.L.1
Boerwinkel, E.2
Chakraborty, R.3
-
128
-
-
0029126604
-
A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin
-
Hansen L, Hansen T, Vestergaard H, Bjørbæk C, Echwald SM, Clausen JO, Chen YH, Chen MX, Cohen PTW, Pedersen O: A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin. Hum. Mol. Genet. 4; 8: 1313-1320, 1995.
-
(1995)
Hum Mol Genet
, vol.4
, Issue.8
, pp. 1313-1320
-
-
Hansen, L.1
Hansen, T.2
Vestergaard, H.3
Bjørbæk, C.4
Echwald, S.M.5
Clausen, J.O.6
Chen, Y.H.7
Chen, M.X.8
Cohen, P.T.W.9
Pedersen, O.10
-
129
-
-
0030875687
-
Chromosomal mapping and mutational analysis of the glycogen synthase kinase-3α and β isoforms in patients with NIDDM
-
Hansen L, Arden KC, Rasmussen SB, Viars CS, Vestergaard H, Hansen T, Møller AM, Woodgett JR, Pedersen O: Chromosomal mapping and mutational analysis of the glycogen synthase kinase-3α and β isoforms in patients with NIDDM. Diabetologia 40: 940-946, 1997a.
-
(1997)
Diabetologia
, vol.40
, pp. 940-946
-
-
Hansen, L.1
Arden, K.C.2
Rasmussen, S.B.3
Viars, C.S.4
Vestergaard, H.5
Hansen, T.6
Møller, A.M.7
Woodgett, J.R.8
Pedersen, O.9
-
130
-
-
0031051534
-
Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir 6.2 and their relationsships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM
-
Hansen L, Echwald SM, Hansen T, Urhammer SA, Clausen JO, Pedersen O: Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir 6.2 and their relationsships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM. Diabetes 46: 508-512, 1997b.
-
(1997)
Diabetes
, vol.46
, pp. 508-512
-
-
Hansen, L.1
Echwald, S.M.2
Hansen, T.3
Urhammer, S.A.4
Clausen, J.O.5
Pedersen, O.6
-
131
-
-
0030923338
-
The Val985Met insulin-receptor variant in the Danish Caucasian population: Lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance
-
Hansen L, Hansen T, Clausen JO, Echwald SM, Urhammer SA, Rasmussen SK, Pedersen O: The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance. Am J Hum Genet 60: 1532-5, 1997c.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 1532-1535
-
-
Hansen, L.1
Hansen, T.2
Clausen, J.O.3
Echwald, S.M.4
Urhammer, S.A.5
Rasmussen, S.K.6
Pedersen, O.7
-
132
-
-
26544450268
-
Genetic dissection of the insulin receptor gene in 82 Danish Caucasian NIDDM families
-
Hansen L, Hansen T, Urhammer SA, Jessing S, Larsen SG, Eiberg H, Pedersen O: Genetic dissection of the insulin receptor gene in 82 Danish Caucasian NIDDM families. Diabetologia 41 (Suppl. 1): A105, 1998.
-
(1998)
Diabetologia
, vol.41
, Issue.SUPPL. 1
-
-
Hansen, L.1
Hansen, T.2
Urhammer, S.A.3
Jessing, S.4
Larsen, S.G.5
Eiberg, H.6
Pedersen, O.7
-
133
-
-
0032896978
-
Mutational Analysis of the Coding Regions of the Genes Encoding Protein Kinase B α and β, Phosphoinositide Dependent Protein Kinase-1
-
Hansen L, Fjordvang H, Rasmussen SK, Vestergaard H, Echwald SM, Hansen T, Alessi D, Shenolikar S, Saltiel AR, Barbetti F, Pedersen O: Mutational Analysis of the Coding Regions of the Genes Encoding Protein Kinase B α and β, Phosphoinositide Dependent Protein Kinase-1, Phosphatase Targeting to Glycogen, Protein Phosphatase Inhibitor-1, and Glycogenin: Lessons from a search for genetic variability of the Insulin Stimulated Glycogen Synthesis Pathway of Skeletal Muscle in NIDDM Patients. Diabetes 48: 403-408, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 403-408
-
-
Hansen, L.1
Fjordvang, H.2
Rasmussen, S.K.3
Vestergaard, H.4
Echwald, S.M.5
Hansen, T.6
Alessi, D.7
Shenolikar, S.8
Saltiel, A.R.9
Barbetti, F.10
Pedersen, O.11
-
134
-
-
0033956880
-
Polymorphism in glycogen associated regulatory subunit of type-1 protein phosphatase (PPP1R3) gene and insulin sensitivity
-
Hansen L, Reneland R, Berglund L, Rasmussen SK, Hansen T, Lithell H, Pedersen O: Polymorphism in glycogen associated regulatory subunit of type-1 protein phosphatase (PPP1R3) gene and insulin sensitivity. Diabetes 49: 298-301, 2000a.
-
(2000)
Diabetes
, vol.49
, pp. 298-301
-
-
Hansen, L.1
Reneland, R.2
Berglund, L.3
Rasmussen, S.K.4
Hansen, T.5
Lithell, H.6
Pedersen, O.7
-
135
-
-
0034454416
-
Missense mutations in insulin promoter factor-1 (IPF-1) gene and their relation to maturity onset diabetes of the young and late onset type 2 diabetes mellitus in Caucasians
-
Hansen L, Urioste S, Petersen HV, Jensen JN, Eiberg H, Barbetti F, Serup P, Hansen T, Pedersen P: Missense mutations in insulin promoter factor-1 (IPF-1) gene and their relation to maturity onset diabetes of the young and late onset type 2 diabetes mellitus in Caucasians. J. Clin. Endocrin. & Metab., 85: 1323-1326, 2000b.
-
(2000)
J Clin Endocrin & Metab
, vol.85
, pp. 1323-1326
-
-
Hansen, L.1
Urioste, S.2
Petersen, H.V.3
Jensen, J.N.4
Eiberg, H.5
Barbetti, F.6
Serup, P.7
Hansen, T.8
Pedersen, P.9
-
136
-
-
0034033618
-
NeuroD/BETA2 gene variability and diabetes mellitus: No associations to late-onset type 2 diabetes mellitus but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes
-
Hansen L, Jensen JN, Urioste S, Petersen HV, Pociot F, Eiberg H, Kristiansen OP, Hansen T, Serup P, Nerup J, DSGD, DIEGG, Pedersen O: NeuroD/BETA2 gene variability and diabetes mellitus: No associations to late-onset type 2 diabetes mellitus but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Diabetes 49: 876-878, 2000c.
-
(2000)
Diabetes
, vol.49
, pp. 876-878
-
-
Hansen, L.1
Jensen, J.N.2
Urioste, S.3
Petersen, H.V.4
Pociot, F.5
Eiberg, H.6
Kristiansen, O.P.7
Hansen, T.8
Serup, P.9
Nerup, J.10
Pedersen, O.11
-
137
-
-
0035095168
-
In vitro and in vivo studies of a naturally occurring variant of the p85α regulatory subunit of the phosphoinositide-3 kinase: Inhibition of protein kinase B, prediction of type 2 diabetes and relationships with insulin secretion, glucose disappearance constant, and insulin sensitivity
-
Hansen L, Zethelius B, Berglund L, Reneland R, Hansen T, Berne C, Lithell H, Hemmings BA, Pedersen O: In vitro and in vivo studies of a naturally occurring variant of the p85α regulatory subunit of the phosphoinositide-3 kinase: inhibition of protein kinase B, prediction of type 2 diabetes and relationships with insulin secretion, glucose disappearance constant, and insulin sensitivity. Diabetes 50: 690-93, 2001a.
-
(2001)
Diabetes
, vol.50
, pp. 690-693
-
-
Hansen, L.1
Zethelius, B.2
Berglund, L.3
Reneland, R.4
Hansen, T.5
Berne, C.6
Lithell, H.7
Hemmings, B.A.8
Pedersen, O.9
-
138
-
-
0035131653
-
Studies of variability in the PTEN gene among Caucasian patients with type II diabetes
-
Hansen L, Jensen JN, Ekstrøm CT, Vestergaard H, Hansen T, Pedersen O: Studies of variability in the PTEN gene among Caucasian patients with type II diabetes. Diabetologia 44: 237-40, 2001b.
-
(2001)
Diabetologia
, vol.44
, pp. 237-240
-
-
Hansen, L.1
Jensen, J.N.2
Ekstrøm, C.T.3
Vestergaard, H.4
Hansen, T.5
Pedersen, O.6
-
139
-
-
0031046812
-
Identification of a common amino acid polymorphism in the p85 alpha regulatory subunit of phosphatidylinositol 3-kinase
-
Hansen T, Andersen CB, Echwald SM, Urhammer SA, Clausen JO, Vestergaard H, Owens D, Hansen L, Pedersen O: Identification of a common amino acid polymorphism in the p85 alpha regulatory subunit of phosphatidylinositol 3-kinase. Diabetes 46: 494-501, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 494-501
-
-
Hansen, T.1
Andersen, C.B.2
Echwald, S.M.3
Urhammer, S.A.4
Clausen, J.O.5
Vestergaard, H.6
Owens, D.7
Hansen, L.8
Pedersen, O.9
-
140
-
-
0031925068
-
Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene
-
Hansen T, Echwald SM, Hansen L, Møller AM, Almind K, Clausen JO, Urhammer SA, Inoue H, Ferrer J, Bryan J, Aguilar-Bryan L, Permutt MA, Pedersen O: Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene. Diabetes 47: 598-605, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 598-605
-
-
Hansen, T.1
Echwald, S.M.2
Hansen, L.3
Møller, A.M.4
Almind, K.5
Clausen, J.O.6
Urhammer, S.A.7
Inoue, H.8
Ferrer, J.9
Bryan, J.10
Aguilar-Bryan, L.11
Permutt, M.A.12
Pedersen, O.13
-
141
-
-
0032231322
-
An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians
-
Hanson RL, Ehm MG, Pettitt DJ, Prochazka M, Thompson DB, Timberlake D, Foroud T, kobes S, baier L, Burns DK, Almasy L, Blangero J, garvey WT, Bennett PH, Knowler WC: An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians. Am J Hum Gen 63: 1130-1138, 1998.
-
(1998)
Am J Hum Gen
, vol.63
, pp. 1130-1138
-
-
Hanson, R.L.1
Ehm, M.G.2
Pettitt, D.J.3
Prochazka, M.4
Thompson, D.B.5
Timberlake, D.6
Foroud, T.7
Kobes, S.8
Baier, L.9
Burns, D.K.10
Almasy, L.11
Blangero, J.12
Garvey, W.T.13
Bennett, P.H.14
Knowler, W.C.15
-
142
-
-
0034728762
-
The Pro12Ale6a polymorphism in PPAR-27 may confer resistance to type 2 diabetes
-
Hara K, Okada T, Tobe K, Yasuda K, Mori Y, Kadowaki H, Hagura R, Akanuma Y, kimura S, Ito C, Kadowaki T: The Pro12Ala polymorphism in PPAR-27 may confer resistance to type 2 diabetes. Biochem Biophys Res Commun 271: 2112-16, 2000.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 2112-2116
-
-
Hara, K.1
Okada, T.2
Tobe, K.3
Yasuda, K.4
Mori, Y.5
Kadowaki, H.6
Hagura, R.7
Akanuma, Y.8
Kimura, S.9
Ito, C.10
Kadowaki, T.11
-
143
-
-
0032860478
-
Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice
-
Harrison KA, Thaler J, Pfaff SL, Gu H, Kehrl JH: Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice. Nature Genetics 23: 71-75, 1999.
-
(1999)
Nature Genetics
, vol.23
, pp. 71-75
-
-
Harrison, K.A.1
Thaler, J.2
Pfaff, S.L.3
Gu, H.4
Kehrl, J.H.5
-
144
-
-
0034649608
-
Attenuation of FGF signalling in mouse beta-cells leads to diabetes
-
Hart AW, Baeza N, Apelqvist A, Edlund H: Attenuation of FGF signalling in mouse beta-cells leads to diabetes. Nature 408: 864-868, 2000.
-
(2000)
Nature
, vol.408
, pp. 864-868
-
-
Hart, A.W.1
Baeza, N.2
Apelqvist, A.3
Edlund, H.4
-
145
-
-
0029907562
-
Association of the insulin receptor variant Met-985 with hyperglycemia and non-insulin dependent diabetes mellitus in the Netherlands: A population-based study
-
t'Hart LM, Stolk RP, Heine RJ, Groebbee DE, van der Does FEE, Maassen JA: Association of the insulin receptor variant Met-985 with hyperglycemia and non-insulin dependent diabetes mellitus in the Netherlands: A population-based study. Am J Hum Genet 59: 1119-1125, 1996.
-
(1996)
Am J Hum Genet
, vol.59
, pp. 1119-1125
-
-
T'Hart, L.M.1
Stolk, R.P.2
Heine, R.J.3
Groebbee, D.E.4
Van Der Does, F.E.E.5
Maassen, J.A.6
-
146
-
-
0033007968
-
Variants in the sulphonylurea receptor gene: Association of the exon 16-3t variant with type II diabetes mellitus in the Dutch Caucasians
-
't Hart LM, de Knijff, Dekker JM, Stolk RP, Nijpels G, van der Does FE, Ruige JB, Grobbee DE, Heine RJ, Maassen JA: Variants in the sulphonylurea receptor gene: association of the exon 16-3t variant with type II diabetes mellitus in the Dutch Caucasians. Diabetologia 42: 617-620, 1999.
-
(1999)
Diabetologia
, vol.42
, pp. 617-620
-
-
'T Hart, L.M.1
De Knijff2
Dekker, J.M.3
Stolk, R.P.4
Nijpels, G.5
Van Der Does, F.E.6
Ruige, J.B.7
Grobbee, D.E.8
Heine, R.J.9
Maassen, J.A.10
-
147
-
-
0033863689
-
Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis
-
Harvest FG, Almgren P, Lindholm E, Frititta L, Pizzuti A, Trischitta V, Groop LC: Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis. Diabetes 49: 1601-3, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 1601-1603
-
-
Harvest, F.G.1
Almgren, P.2
Lindholm, E.3
Frititta, L.4
Pizzuti, A.5
Trischitta, V.6
Groop, L.C.7
-
148
-
-
0030846804
-
Recessive inheritance of obesity in familial non-insulin dependent diabetes mellitus, and lack of linkage to nine candidate genes
-
Hasstedt SJ, Hoffman M, Leppert MF, Elbein SC: Recessive inheritance of obesity in familial non-insulin dependent diabetes mellitus, and lack of linkage to nine candidate genes. Am J Hum Genet 61: 668-77, 1997.
-
(1997)
Am J Hum Genet
, vol.61
, pp. 668-677
-
-
Hasstedt, S.J.1
Hoffman, M.2
Leppert, M.F.3
Elbein, S.C.4
-
149
-
-
0026583193
-
Linkage of type 2 diabetes to the glucokinase gene
-
Hattersley AT, Turner RC, Permutt MA, Patel P, Tanizawa Y, Chiu KC, O'Rahilly S, Watkins PJ, Wainscoat JS: Linkage of type 2 diabetes to the glucokinase gene. Lancet 339: 1307-10, 1992.
-
(1992)
Lancet
, vol.339
, pp. 1307-1310
-
-
Hattersley, A.T.1
Turner, R.C.2
Permutt, M.A.3
Patel, P.4
Tanizawa, Y.5
Chiu, K.C.6
O'Rahilly, S.7
Watkins, P.J.8
Wainscoat, J.S.9
-
150
-
-
0031859976
-
Mutations in the glucokinase gene of the fetus result in reduced birth weight
-
Hattersley AT, Beards F, Ballantyne E, Appleton M, Harvey R, Ellard S: Mutations in the glucokinase gene of the fetus result in reduced birth weight. Nat Genet 19: 268-71, 1998.
-
(1998)
Nat Genet
, vol.19
, pp. 268-271
-
-
Hattersley, A.T.1
Beards, F.2
Ballantyne, E.3
Appleton, M.4
Harvey, R.5
Ellard, S.6
-
151
-
-
0033847438
-
S20G mutation of the amylin gene in Japanese patients with type 2 diabetes
-
Hayakawa T, Nagai Y, Ando H, Yamashita H, Takamura T, Abe T, Nomura G, Kobayashi KI: S20G mutation of the amylin gene in Japanese patients with type 2 diabetes. Diabetes Res Clin Pract; 49: 195-197, 2000.
-
(2000)
Diabetes Res Clin Pract
, vol.49
, pp. 195-197
-
-
Hayakawa, T.1
Nagai, Y.2
Ando, H.3
Yamashita, H.4
Takamura, T.5
Abe, T.6
Nomura, G.7
Kobayashi, K.I.8
-
152
-
-
0033857978
-
Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans
-
Hebinck J, Hardt C, Schols L, Vorgerd M, Briedigkeit L, kahn CR, Ristow M: Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans. Diabetes 49: 1604.1607, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 1604-1607
-
-
Hebinck, J.1
Hardt, C.2
Schols, L.3
Vorgerd, M.4
Briedigkeit, L.5
Kahn, C.R.6
Ristow, M.7
-
153
-
-
0016777296
-
A study of middle-aged men with particular reference to risk factors for cardiovascular disease
-
Hedstrand H: A study of middle-aged men with particular reference to risk factors for cardiovascular disease. Upsala J Med Sci 80 (Suppl.19):161,1975.
-
(1975)
Upsala J Med Sci
, vol.80
, Issue.SUPPL. 19
, pp. 161
-
-
Hedstrand, H.1
-
154
-
-
0031763878
-
Variation in the AU(AT)-rich element within the 3′-untranslated region of PPP1R3 is associated with variation in plasma glucose in aboriginal Canadians
-
Hegele RA, Harris SB, Zinman B, Wang J, Cao H, Hanley AJ, Tsui LC, Scherer SW: Variation in the AU(AT)-rich element within the 3′ -untranslated region of PPP1R3 is associated with variation in plasma glucose in aboriginal Canadians. J Clin Endocrinol Metab 83: 3980-83, 1998.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 3980-3983
-
-
Hegele, R.A.1
Harris, S.B.2
Zinman, B.3
Wang, J.4
Cao, H.5
Hanley, A.J.6
Tsui, L.C.7
Scherer, S.W.8
-
155
-
-
0032695529
-
A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes
-
Hill MM, Clark SF, Tucker DF, Birnbaum MJ, James DE, Macaulay SL: A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes. Mol Cell Biol 19: 7771-81, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7771-7781
-
-
Hill, M.M.1
Clark, S.F.2
Tucker, D.F.3
Birnbaum, M.J.4
James, D.E.5
Macaulay, S.L.6
-
156
-
-
0028912848
-
Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease
-
Hitman GA, Hawrami K, McCarthy MI, Viswanathan M, Snehalatha C, Ramachandran A, Tuomilehto J, Tuomilehto-Wolf E, Nissinen A, Pedersen O: Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease. Diabetologia 38: 481-86, 1995.
-
(1995)
Diabetologia
, vol.38
, pp. 481-486
-
-
Hitman, G.A.1
Hawrami, K.2
McCarthy, M.I.3
Viswanathan, M.4
Snehalatha, C.5
Ramachandran, A.6
Tuomilehto, J.7
Tuomilehto-Wolf, E.8
Nissinen, A.9
Pedersen, O.10
-
157
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR: Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406: 86-90, 2000.
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
158
-
-
0031016126
-
Insulin resistance in short children with intrauterine growth retardation
-
Hofman PL, Cutfield WS, Robinson EM, Bergman RN, Menon RK, Sperling MA, Gluckman PD: Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab 82: 402-406, 1997.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 402-406
-
-
Hofman, P.L.1
Cutfield, W.S.2
Robinson, E.M.3
Bergman, R.N.4
Menon, R.K.5
Sperling, M.A.6
Gluckman, P.D.7
-
159
-
-
0031453186
-
Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY
-
Horikawa Y, Iwasaki N, Hara M, Furuta H, Hinokio Y, Cockburn BN, Lindner T, Yamagata K, Ogata M, Tomnaga O, Kuroki H, Kasahara T, Iwamoto Y, Bell GI: Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nature Genetics 17: 384-385, 1997.
-
(1997)
Nature Genetics
, vol.17
, pp. 384-385
-
-
Horikawa, Y.1
Iwasaki, N.2
Hara, M.3
Furuta, H.4
Hinokio, Y.5
Cockburn, B.N.6
Lindner, T.7
Yamagata, K.8
Ogata, M.9
Tomnaga, O.10
Kuroki, H.11
Kasahara, T.12
Iwamoto, Y.13
Bell, G.I.14
-
160
-
-
0033772073
-
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
-
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PEH, del Bosque-Plata, Horikawa Y, Oda Y, Yoshiuchi I, colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI: Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 26: 163-75, 2000.
-
(2000)
Nat Genet
, vol.26
, pp. 163-175
-
-
Horikawa, Y.1
Oda, N.2
Cox, N.J.3
Li, X.4
Orho-Melander, M.5
Hara, M.6
Hinokio, Y.7
Lindner, T.H.8
Mashima, H.9
Schwarz, P.E.H.10
Del Bosque-Plata11
Horikawa, Y.12
Oda, Y.13
Yoshiuchi, I.14
Colilla, S.15
Polonsky, K.S.16
Wei, S.17
Concannon, P.18
Iwasaki, N.19
Schulze, J.20
Baier, L.J.21
Bogardus, C.22
Groop, L.23
Boerwinkle, E.24
Hanis, C.L.25
Bell, G.I.26
more..
-
161
-
-
0034351407
-
The Gly→Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells
-
Hribal ML, Federici M, Porzio O, Lauro D, Borboni P, Accili D, Lauro R, Sesti G: The Gly→Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells. J Clin Endocrinol Metab 85: 2004-13, 2000.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2004-2013
-
-
Hribal, M.L.1
Federici, M.2
Porzio, O.3
Lauro, D.4
Borboni, P.5
Accili, D.6
Lauro, R.7
Sesti, G.8
-
162
-
-
0033996527
-
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3
-
Huang HP, Liu M, El-Hodiri HM, Chu K, Jamrich M, Tsai MJ: Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol Cell Biol 20: 3297-307, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3297-3307
-
-
Huang, H.P.1
Liu, M.2
El-Hodiri, H.M.3
Chu, K.4
Jamrich, M.5
Tsai, M.J.6
-
163
-
-
0029051799
-
Lack of association between the Gly40Ser polymorphism in the glucagon receptor gene and NIDDM in Finland
-
Huang X, Orho M, Lehto M, Groop L: Lack of association between the Gly40Ser polymorphism In the glucagon receptor gene and NIDDM in Finland. Diabetologia 38: 1246-48, 1995.
-
(1995)
Diabetologia
, vol.38
, pp. 1246-1248
-
-
Huang, X.1
Orho, M.2
Lehto, M.3
Groop, L.4
-
164
-
-
0027277098
-
On target with a new mechanism for the regulation of protein phosphatase
-
Hubbard MJ, Cohen P: On target with a new mechanism for the regulation of protein phosphatase. TIBS 18: 172-177, 1993.
-
(1993)
TIBS
, vol.18
, pp. 172-177
-
-
Hubbard, M.J.1
Cohen, P.2
-
165
-
-
0027475421
-
Modulation of glycogen synthase kinase-3 family by tyrosine phosphorylation
-
Hughes K, Nikolakaki E, Plyte SE, Totty NF, Woodgett JR: Modulation of glycogen synthase kinase-3 family by tyrosine phosphorylation. EMBO J. 12; 2: 803-808, 1993.
-
(1993)
EMBO J
, vol.12
, Issue.2
, pp. 803-808
-
-
Hughes, K.1
Nikolakaki, E.2
Plyte, S.E.3
Totty, N.F.4
Woodgett, J.R.5
-
166
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O'Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G: Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411: 599-603, 2001.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
Macry, J.17
Colombel, J.F.18
Sahbatou, M.19
Thomas, G.20
more..
-
167
-
-
0033959416
-
Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles
-
Huxtable SJ, Saker PJ, Haddad L, Walker M, Frayling TM, Levy JC, Hitman GA, O'Rahilly S, Hattersley AT, McCarthy MI: Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles. Diabetes 49: 126-30, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 126-130
-
-
Huxtable, S.J.1
Saker, P.J.2
Haddad, L.3
Walker, M.4
Frayling, T.M.5
Levy, J.C.6
Hitman, G.A.7
O'Rahilly, S.8
Hattersley, A.T.9
McCarthy, M.I.10
-
168
-
-
0028972501
-
KATP: An inwardly rectifier subunit plus the sulfonylurea receptor
-
KATP: An inwardly rectifier subunit plus the sulfonylurea receptor. Science 270: 1166-1170, 1995.
-
(1995)
Science
, vol.270
, pp. 1166-1170
-
-
Inagaki, N.1
Gonoi, T.2
Clement, J.P.3
Namba, N.4
Inazawa, J.5
Gonzalez, G.6
Aguilar-Bryan, L.7
Seino, S.8
Bryan, J.9
-
169
-
-
0029898253
-
+ Channels
-
+ Channels. Neuron 16: 1011-1017, 1996.
-
(1996)
Neuron
, vol.16
, pp. 1011-1017
-
-
Inagaki, N.1
Gonoi, T.2
Clement IV, J.P.3
Wang, C.-Z.4
Aguilar-Bryan, L.5
Bryan, J.6
Seino, S.7
-
170
-
-
15844366738
-
Sequence variants in the sulphonylurea receptor (SUR) gene are associated with NIDDM in Caucasians
-
Inoue H, Ferrer J, Welling CM, Elbein SC, Hoffman M, Mayorgata R, Warren-Perry M, Zhang Y, Millns H, Turner R, Province M, Bryan J, Permutt MA, Aguilar-Bryan L: Sequence variants in the sulphonylurea receptor (SUR) gene are associated with NIDDM in Caucasians. Diabetes 45: 825-31, 1995.
-
(1995)
Diabetes
, vol.45
, pp. 825-831
-
-
Inoue, H.1
Ferrer, J.2
Welling, C.M.3
Elbein, S.C.4
Hoffman, M.5
Mayorgata, R.6
Warren-Perry, M.7
Zhang, Y.8
Millns, H.9
Turner, R.10
Province, M.11
Bryan, J.12
Permutt, M.A.13
Aguilar-Bryan, L.14
-
171
-
-
15144338831
-
+ channel Kir6.2 (Bir) gene: Identification and lack of role in Caucasian patients with NIDDM
-
+ channel Kir6.2 (Bir) gene: identification and lack of role in Caucasian patients with NIDDM. Diabetes 46: 502-7,1997.
-
(1997)
Diabetes
, vol.46
, pp. 502-507
-
-
Inoue, H.1
Ferrer, J.2
Warren-Perry, M.3
Zhang, Y.4
Millns, H.5
Turner, R.C.6
Elbein, S.C.7
Hampe, C.L.8
Suarez, B.K.9
Inagaki, N.10
Seino, S.11
Permutt, M.A.12
-
172
-
-
0030615068
-
p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin
-
Inukai K, Funaki M, Ogihara T, Katagiri H, Kanda A, Anai M, Fukushima Y, Hosaka T, Suzuki M, Shin BC, Takata K, Yazaki Y, Kikuchi M, Oka Y, Asano T: p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin. J Biol Chem 212: 7873-82, 1997.
-
(1997)
J Biol Chem
, vol.212
, pp. 7873-7882
-
-
Inukai, K.1
Funaki, M.2
Ogihara, T.3
Katagiri, H.4
Kanda, A.5
Anai, M.6
Fukushima, Y.7
Hosaka, T.8
Suzuki, M.9
Shin, B.C.10
Takata, K.11
Yazaki, Y.12
Kikuchi, M.13
Oka, Y.14
Asano, T.15
-
173
-
-
0033047379
-
Association of polymorphism in the NeuroD/Beta2 gene with type 1 diabetes in the Japanese
-
Isao I, Nagafuchi S, Nakashima H, Kondo S Koga T, Yokogawa Y, Akashi T, Shibuya T, Umeno Y, Okeda T, Shibata S, Kono S, Yasunami M, Ohkubo H, Niho Y: Association of polymorphism in the NeuroD/Beta2 gene with type 1 diabetes in the Japanese. Diabetes 48: 416-419, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 416-419
-
-
Isao, I.1
Nagafuchi, S.2
Nakashima, H.3
Kondo, S.4
Koga, T.5
Yokogawa, Y.6
Akashi, T.7
Shibuya, T.8
Umeno, Y.9
Okeda, T.10
Shibata, S.11
Kono, S.12
Yasunami, M.13
Ohkubo, H.14
Niho, Y.15
-
174
-
-
13344259308
-
+ channel and linkage studies with NIDDM in Japanese
-
+ channel and linkage studies with NIDDM in Japanese. Diabetes 45: 267-269, 1995.
-
(1995)
Diabetes
, vol.45
, pp. 267-269
-
-
Iwasaki, N.1
Kawamura, M.2
Yamagata, K.3
Cox, N.J.4
Karibe, S.5
Ohgawara, H.6
Inagaki, N.7
Seino, S.8
Bell, G.I.9
Omori, Y.10
-
175
-
-
19244372001
-
Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3
-
Jacquemin P, Durviaux SM, Jensen J, Godfraind C, Gradwohl G, Guillemot F, Madsen OD, Carmeliet P, Dewerchin M, Collen D, Rousseau GG, Lemaigre FP: Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3. Mol Cell Biol 20: 4445-4454, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4445-4454
-
-
Jacquemin, P.1
Durviaux, S.M.2
Jensen, J.3
Godfraind, C.4
Gradwohl, G.5
Guillemot, F.6
Madsen, O.D.7
Carmeliet, P.8
Dewerchin, M.9
Collen, D.10
Rousseau, G.G.11
Lemaigre, F.P.12
-
176
-
-
0032731961
-
Effect of intrauterine growth restriction on blood pressure, glucose tolerance and sympathetic nervous system activity in the rat at 3-4 months of age
-
Jansson T, Lambert GW: Effect of intrauterine growth restriction on blood pressure, glucose tolerance and sympathetic nervous system activity in the rat at 3-4 months of age. J Hypertens 17: 1239-1248, 1999.
-
(1999)
J Hypertens
, vol.17
, pp. 1239-1248
-
-
Jansson, T.1
Lambert, G.W.2
-
177
-
-
0033578776
-
90 kDa ribosomal S6 kinase (RSK) is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1 (PDK1)
-
Jensen CJ, Buch M-B, Krag TO, Hemmings BA, Gammeltoft S, Frödin M: 90 kDa ribosomal S6 kinase (RSK) is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1 (PDK1). J Biol Chem 274: 27168-27176, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 27168-27176
-
-
Jensen, C.J.1
Buch, M.-B.2
Krag, T.O.3
Hemmings, B.A.4
Gammeltoft, S.5
Frödin, M.6
-
178
-
-
18544404101
-
Control of endodermal endocrine differentiation by Hes-1
-
Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, Kageyama R, Guillemot F, Serup P, Madsen OD: Control of endodermal endocrine differentiation by Hes-1. Nat Genet 24: 36-44, 1999.
-
(1999)
Nat Genet
, vol.24
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
Hald, J.4
Heller, R.S.5
Ishibashi, M.6
Kageyama, R.7
Guillemot, F.8
Serup, P.9
Madsen, O.D.10
-
179
-
-
0033984886
-
Independent development of pancreatic alpha-and beta-cells from neurogenin3-expressing precursors: A role for the notch pathway in repression of premature differentiation
-
Jensen J, Heller RS, Funder-Nielsen T, Pedersen EE, Lindsell C, Weinmaster G, Madsen OD, Serup P: Independent development of pancreatic alpha-and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. Diabetes 49: 163-76, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 163-176
-
-
Jensen, J.1
Heller, R.S.2
Funder-Nielsen, T.3
Pedersen, E.E.4
Lindsell, C.5
Weinmaster, G.6
Madsen, O.D.7
Serup, P.8
-
180
-
-
0035124665
-
Polymorphisms in the human neurogenin 3 gene and their relationships to altered insulin secretion and diabetes in the Danish population
-
Jensen JN, Hansen L, Ekstrøm CT, Pociot F, Nerup J, Hansen T, Pedersen O: Polymorphisms in the human neurogenin 3 gene and their relationships to altered insulin secretion and diabetes in the Danish population. Diabetologia 44: 123-26, 2001.
-
(2001)
Diabetologia
, vol.44
, pp. 123-126
-
-
Jensen, J.N.1
Hansen, L.2
Ekstrøm, C.T.3
Pociot, F.4
Nerup, J.5
Hansen, T.6
Pedersen, O.7
-
181
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J, Carlsson L, Edlund T, Edlund H: Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371: 606-609, 1994.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
182
-
-
0023896248
-
Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance
-
Kadowaki T, Bevins CL, Cama A, Ojamaa K, Marcus-Samuels B, Kadowaki H, McKeon C, Taylor SI: Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. Science 240: 787-790, 1988.
-
(1988)
Science
, vol.240
, pp. 787-790
-
-
Kadowaki, T.1
Bevins, C.L.2
Cama, A.3
Ojamaa, K.4
Marcus-Samuels, B.5
Kadowaki, H.6
McKeon, C.7
Taylor, S.I.8
-
183
-
-
0028822448
-
Frequency of mutations of the insulin receptor gene in Japanese patients with NIDDM
-
Kan M, Kanai F, Iida M, Jinnouchi H, Todaka M, Imanaka T, Ito K, Nishioka Y, Ohnishi T, Kamohara S, Hayashi H, Murakami T, Kagawa S, Sano H, Hashimoto N, Yoshida S, Makino H, Ebina Y: Frequency of mutations of the insulin receptor gene in Japanese patients with NIDDM. Diabetes 44: 1081-86, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 1081-1086
-
-
Kan, M.1
Kanai, F.2
Iida, M.3
Jinnouchi, H.4
Todaka, M.5
Imanaka, T.6
Ito, K.7
Nishioka, Y.8
Ohnishi, T.9
Kamohara, S.10
Hayashi, H.11
Murakami, T.12
Kagawa, S.13
Sano, H.14
Hashimoto, N.15
Yoshida, S.16
Makino, H.17
Ebina, Y.18
-
184
-
-
0031157826
-
Prevalence of a polymorphism of the phosphatidylinositol 3-kinase p85α regulatory subunit (codon 326 Met→Ile) in Japanese NIDDM patients
-
Kawanishi M, Tamori Y, Masugi J, Mori H, Ito C, Hansen T, Andersen CB, Pedersen O, Kasuga M: Prevalence of a polymorphism of the phosphatidylinositol 3-kinase p85α regulatory subunit (codon 326 Met→Ile) in Japanese NIDDM patients. Diabetes Care 20; 6: 1043, 1997.
-
(1997)
Diabetes Care
, vol.20
, Issue.6
, pp. 1043
-
-
Kawanishi, M.1
Tamori, Y.2
Masugi, J.3
Mori, H.4
Ito, C.5
Hansen, T.6
Andersen, C.B.7
Pedersen, O.8
Kasuga, M.9
-
185
-
-
0028881617
-
The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription
-
Kennedy GC, German MS, Rutter WJ: The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. Nature Genetics 9: 293-298, 1995.
-
(1995)
Nature Genetics
, vol.9
, pp. 293-298
-
-
Kennedy, G.C.1
German, M.S.2
Rutter, W.J.3
-
186
-
-
0025117502
-
Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle
-
Kida Y, Esposito-Del Puente A, Bogardus C, Mott DM: Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle. J Clin Invest 85: 476-481, 1990.
-
(1990)
J Clin Invest
, vol.85
, pp. 476-481
-
-
Kida, Y.1
Esposito-Del Puente, A.2
Bogardus, C.3
Mott, D.M.4
-
187
-
-
0026520896
-
Defective insulin response of phosphorylase phosphatase in insulin-resistant humans
-
Kida Y, Raz I, Maeda R, Nyomba BL, Bogardus C, Sommercom J, Mott DM: Defective insulin response of phosphorylase phosphatase in insulin-resistant humans. J Clin Invest 89: 610-617, 1992.
-
(1992)
J Clin Invest
, vol.89
, pp. 610-617
-
-
Kida, Y.1
Raz, I.2
Maeda, R.3
Nyomba, B.L.4
Bogardus, C.5
Sommercom, J.6
Mott, D.M.7
-
188
-
-
0033966768
-
Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2
-
Kido Y, Burks DJ, Withers D, Brüning JC, kahn CR, White MF, Accili D: Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2. J Clin Invest 105: 199-205, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 199-205
-
-
Kido, Y.1
Burks, D.J.2
Withers, D.3
Brüning, J.C.4
Kahn, C.R.5
White, M.F.6
Accili, D.7
-
189
-
-
0035006359
-
Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes
-
Kim SH, Warram JH, Krolewski AS, Doria A: Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes. J Clin Endocrinol Metab 86: 2320-22, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 2320-2322
-
-
Kim, S.H.1
Warram, J.H.2
Krolewski, A.S.3
Doria, A.4
-
190
-
-
0034085886
-
Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats
-
Kim Y-B, Peroni OD, Franke TF, Kahn BB: Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats. Diabetes 49: 847-856, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 847-856
-
-
Kim, Y.-B.1
Peroni, O.D.2
Franke, T.F.3
Kahn, B.B.4
-
191
-
-
14344273991
-
Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome
-
Kissebah AH, Sonnenberg GE, Myklebust J, Goldstein M, Broman K, James RG, Marks JA, Krakower GR, Jacob HJ, Weber J, Martin L, Blangero J, Comuzzie AG: Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci 97: 14478-83, 2000.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 14478-14483
-
-
Kissebah, A.H.1
Sonnenberg, G.E.2
Myklebust, J.3
Goldstein, M.4
Broman, K.5
James, R.G.6
Marks, J.A.7
Krakower, G.R.8
Jacob, H.J.9
Weber, J.10
Martin, L.11
Blangero, J.12
Comuzzie, A.G.13
-
192
-
-
0028881784
-
Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM
-
Klein HH, Vestergaard H, Kotzke G, Pedersen O: Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM. Diabetes 44: 1310-17, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 1310-1317
-
-
Klein, H.H.1
Vestergaard, H.2
Kotzke, G.3
Pedersen, O.4
-
193
-
-
0029908016
-
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
Kohn AD, Summers SA, Birnbaum MJ, Roth RA: Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J Biol Chem 271: 31271-8, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 31271-31278
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
194
-
-
0033815162
-
Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: Cloning, genomic structure, and screening for variants in patients with type 2 diabetes
-
Kossila M, Sinkovic M, Karkkainen P, Laukkanen MO, Miettinen R, Rissanen J, Kekalainen P, Kuusisto J, Yla-Herttuala S, Laakso M: Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes. Diabetes 49: 1740-43, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 1740-1743
-
-
Kossila, M.1
Sinkovic, M.2
Karkkainen, P.3
Laukkanen, M.O.4
Miettinen, R.5
Rissanen, J.6
Kekalainen, P.7
Kuusisto, J.8
Yla-Herttuala, S.9
Laakso, M.10
-
195
-
-
0033558098
-
ATP channels: Control of nucleotide sensitivity by the N-terminal domain of the Kir6.2 subunit
-
ATP channels: control of nucleotide sensitivity by the N-terminal domain of the Kir6.2 subunit. J Physiol 515: 19-30, 1999.
-
(1999)
J Physiol
, vol.515
, pp. 19-30
-
-
Koster, J.C.1
Sha, Q.2
Shyng, S.-L.3
Nichols, C.G.4
-
197
-
-
0031778069
-
Spectrum and frequency of jagged1 (Jag 1) mutations in Alagille syndrome patients and their families
-
Krantz ID, Colliton RP, Genin A, Rand EB, Li L, Piccoli DA, Spinner NB: Spectrum and frequency of jagged1 (Jag 1) mutations in Alagille syndrome patients and their families. Am J Hum Genet 62: 1361-1369, 1998.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1361-1369
-
-
Krantz, I.D.1
Colliton, R.P.2
Genin, A.3
Rand, E.B.4
Li, L.5
Piccoli, D.A.6
Spinner, N.B.7
-
199
-
-
0034146742
-
Extended transmission disequilibrium testing reveals linkage of IDDM7 on 2q31 to insulin-dependent diabetes mellitus in Danish multiplex families but linkage is not explained by novel polymorphisms in the candidate gene GALNT3
-
Kristiansen OP, Pociot F, Bennett EP, Clausen H, Johannesen J, Nerup J, Mandrup-Poulsen T: Extended transmission disequilibrium testing reveals linkage of IDDM7 on 2q31 to insulin-dependent diabetes mellitus in Danish multiplex families but linkage is not explained by novel polymorphisms in the candidate gene GALNT3. Human Mutation 15: 295-96, 2000.
-
(2000)
Human Mutation
, vol.15
, pp. 295-296
-
-
Kristiansen, O.P.1
Pociot, F.2
Bennett, E.P.3
Clausen, H.4
Johannesen, J.5
Nerup, J.6
Mandrup-Poulsen, T.7
-
200
-
-
0028047457
-
Molecular scanning of the insulin receptor gene in syndromes of insulin resistance
-
Krook A, Kumar S, Laing I, Boulton AJM, Wass JAH, O'Rahilly: Molecular scanning of the insulin receptor gene in syndromes of insulin resistance. Diabetes 43: 357-68, 1994.
-
(1994)
Diabetes
, vol.43
, pp. 357-368
-
-
Krook, A.1
Kumar, S.2
Laing, I.3
Boulton, A.J.M.4
Wass, J.A.H.5
O'Rahilly6
-
201
-
-
0031852665
-
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
-
Krook A, Roth RA, Jiang XJ, Zierath JR, Wallberg-Henriksson H: Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. Diabetes 47: 1281-86, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 1281-1286
-
-
Krook, A.1
Roth, R.A.2
Jiang, X.J.3
Zierath, J.R.4
Wallberg-Henriksson, H.5
-
202
-
-
0343314906
-
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients
-
Krook A, Bjornholm M, Galuska D, Jiang XJ, Fahlman R, Myers MG Jr, Wallberg-Henriksson H, Zierath JR: Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. Diabetes 49: 284-92, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 284-292
-
-
Krook, A.1
Bjornholm, M.2
Galuska, D.3
Jiang, X.J.4
Fahlman, R.5
Myers Jr., M.G.6
Wallberg-Henriksson, H.7
Zierath, J.R.8
-
203
-
-
0030999123
-
Are animal models of diabetes relevant to the study of the genetics of non-insulin-dependent diabetes in humans?
-
Ktorza A, Bernard C, Parent V, Penicaud L, Froguel P, Lathrop M, Gaugier D: Are animal models of diabetes relevant to the study of the genetics of non-insulin-dependent diabetes in humans? Diabetes Metab 23 suppl 2: 38-46, 1997.
-
(1997)
Diabetes Metab
, vol.23
, Issue.SUPPL. 2
, pp. 38-46
-
-
Ktorza, A.1
Bernard, C.2
Parent, V.3
Penicaud, L.4
Froguel, P.5
Lathrop, M.6
Gaugier, D.7
-
204
-
-
0033524937
-
Tissue-specific knockout of the insulin receptor in pancreatic β-cells creates an insulin secretory defect similar to that in type 2 diabetes
-
Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR: Tissue-specific knockout of the insulin receptor in pancreatic β-cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96: 329-39, 1999a.
-
(1999)
Cell
, vol.96
, pp. 329-339
-
-
Kulkarni, R.N.1
Brüning, J.C.2
Winnay, J.N.3
Postic, C.4
Magnuson, M.A.5
Kahn, C.R.6
-
205
-
-
0033379267
-
Altered function of insulin receptor substrate-1-deficient mouse islets and cultured β-cell lines
-
Kulkaini RN, Winnay JN, Daniels M, Brüning J, Flier SN, Hanahan D, Kahn CR: Altered function of insulin receptor substrate-1-deficient mouse islets and cultured β-cell lines. J Clin Invest 104: R69-75, 1999b.
-
(1999)
J Clin Invest
, vol.104
-
-
Kulkaini, R.N.1
Winnay, J.N.2
Daniels, M.3
Brüning, J.4
Flier, S.N.5
Hanahan, D.6
Kahn, C.R.7
-
206
-
-
0034976644
-
Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas
-
Kurose K, Zhou XP, Araki T, Cannistra SA, Maher ER, Eng C: Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas. Am J Pathol 158: 2097-106, 2001.
-
(2001)
Am J Pathol
, vol.158
, pp. 2097-2106
-
-
Kurose, K.1
Zhou, X.P.2
Araki, T.3
Cannistra, S.A.4
Maher, E.R.5
Eng, C.6
-
207
-
-
0002872316
-
Empirical risk figures for first-degree relatives of noninsulin dependent diabetics
-
Köbberling J, Tattersall R (eds). Academic Press, London, New York
-
Köbberling J, Tillil H: Empirical risk figures for first-degree relatives of noninsulin dependent diabetics. In: Köbberling J, Tattersall R (eds) Sereno Symposium No 47. The Genetics of Diabetes Mellitus. Academic Press, London, New York, pp 201-9, 1982.
-
(1982)
Sereno Symposium No 47. The Genetics of Diabetes Mellitus
, pp. 201-209
-
-
Köbberling, J.1
Tillil, H.2
-
208
-
-
0028914027
-
Amino acid substututions in hexokinase II among patients with NIDDM
-
Laakso M, Malkki M, Deeb SS: Amino acid substututions in hexokinase II among patients with NIDDM. Diabetes 44: 330-334, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 330-334
-
-
Laakso, M.1
Malkki, M.2
Deeb, S.S.3
-
209
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J: Initial sequencing and analysis of the human genome: Nature 409: 860-921, 2001.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
-
210
-
-
0023808322
-
Effect of acute administration of insulin-like growth factor 1 in patients with Laron-type dwarfism
-
Laron Z, Klinger B, Erster B, Anin S: Effect of acute administration of insulin-like growth factor 1 in patients with Laron-type dwarfism. Lancet 8621: 1170-72, 1988.
-
(1988)
Lancet
, vol.8621
, pp. 1170-1172
-
-
Laron, Z.1
Klinger, B.2
Erster, B.3
Anin, S.4
-
211
-
-
0031792118
-
Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue
-
Lauro D, Kido Y, castle AL, Zamowski MJ, Hayashi H, Ebina Y, Accili D: Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue. Nature Genetics 20, 294-98, 1998.
-
(1998)
Nature Genetics
, vol.20
, pp. 294-298
-
-
Lauro, D.1
Kido, Y.2
Castle, A.L.3
Zamowski, M.J.4
Hayashi, H.5
Ebina, Y.6
Accili, D.7
-
212
-
-
0030984321
-
New insights into the role and mechanism of glycogen synthase activation by insulin
-
Lawrence JC, Roach PJ: New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes 46: 541-547, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 541-547
-
-
Lawrence, J.C.1
Roach, P.J.2
-
213
-
-
0031944313
-
Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse
-
Lee YH, Sauer B, Gonzalez FJ: Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse. Mol Cell Biol 18: 3059-68, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3059-3068
-
-
Lee, Y.H.1
Sauer, B.2
Gonzalez, F.J.3
-
214
-
-
0343518970
-
Insulin sensitivity and insulin secretion in monogenic and dizygotic twins
-
Lehtovirta M, Kaprio J, Forsblom C, Eriksson J, Toumitehto J, Groop L: Insulin sensitivity and insulin secretion in monogenic and dizygotic twins. Doiabetologia 43: 285-293, 2000.
-
(2000)
Doiabetologia
, vol.43
, pp. 285-293
-
-
Lehtovirta, M.1
Kaprio, J.2
Forsblom, C.3
Eriksson, J.4
Toumitehto, J.5
Groop, L.6
-
215
-
-
0032061042
-
Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways
-
Leibiger IB, Leibiger B, Moede T, Berggren P-O: Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways. Moll Cell 1: 933-38, 1998.
-
(1998)
Moll Cell
, vol.1
, pp. 933-938
-
-
Leibiger, I.B.1
Leibiger, B.2
Moede, T.3
Berggren, P.-O.4
-
216
-
-
0032482973
-
Short-term regulation of insulin gene transcription by glucose
-
Leibiger B, Moede T, Schwarz T, Brown GR, Köhler M, Leibiger IB, Berggren P-O: Short-term regulation of insulin gene transcription by glucose. Proc Natl Acad Sci 95: 9307-12, 1998.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 9307-9312
-
-
Leibiger, B.1
Moede, T.2
Schwarz, T.3
Brown, G.R.4
Köhler, M.5
Leibiger, I.B.6
Berggren, P.-O.7
-
217
-
-
0034704166
-
Overexpression of protein targeting to glycogen in cultured human muscle cells stimulates glycogen synthesis independent of glycogen and glucose 6-phosphate levels
-
Lerin C, Montell E, Berman HK, Newgard CB, Gomez-Foix AM: Overexpression of protein targeting to glycogen in cultured human muscle cells stimulates glycogen synthesis independent of glycogen and glucose 6-phosphate levels. J Biol Chem 275: 39991-95, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 39991-39995
-
-
Lerin, C.1
Montell, E.2
Berman, H.K.3
Newgard, C.B.4
Gomez-Foix, A.M.5
-
218
-
-
0033662314
-
The insulin gene VNTR is associated with fasting insulin levels and the development of juvenile obesity
-
Le Stunff C, Fallin D, Schork NJ, Bougnères P: The insulin gene VNTR is associated with fasting insulin levels and the development of juvenile obesity. Nat Genet 26: 444-446, 2000.
-
(2000)
Nat Genet
, vol.26
, pp. 444-446
-
-
Le Stunff, C.1
Fallin, D.2
Schork, N.J.3
Bougnères, P.4
-
219
-
-
0032844643
-
Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9
-
Li H, Arber S, Jessell TM, Edlund H: Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9. Nature Genetics 23: 67-70, 1999.
-
(1999)
Nature Genetics
, vol.23
, pp. 67-70
-
-
Li, H.1
Arber, S.2
Jessell, T.M.3
Edlund, H.4
-
220
-
-
0023640773
-
In vivo insulin action is familial characteristic in nondiabetic Pima Indians
-
Lillioja S, Mott DM, Zawadzki JK, Young AA, Abbott WG, Knowler WC, Bennett PH, Moll P, Bogardus C: In vivo insulin action is familial characteristic in nondiabetic Pima Indians. Diabetes 36: 1329-1335, 1987.
-
(1987)
Diabetes
, vol.36
, pp. 1329-1335
-
-
Lillioja, S.1
Mott, D.M.2
Zawadzki, J.K.3
Young, A.A.4
Abbott, W.G.5
Knowler, W.C.6
Bennett, P.H.7
Moll, P.8
Bogardus, C.9
-
221
-
-
0030980371
-
The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 nonHispanic white affected sibships
-
Lindner T, Cragnoli C, Schulze J, Rietzsch H, Petzold C, Schroder HE, Cox NJ, Bell GI: The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 nonHispanic white affected sibships. Diabetes 46: 1227-1229, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1227-1229
-
-
Lindner, T.1
Cragnoli, C.2
Schulze, J.3
Rietzsch, H.4
Petzold, C.5
Schroder, H.E.6
Cox, N.J.7
Bell, G.I.8
-
222
-
-
0030056272
-
Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years
-
Lithell HO, McKeigue PM, Berglund L, Mohsen R, Lithell U-B: Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 312: 406-10, 1996.
-
(1996)
BMJ
, vol.312
, pp. 406-410
-
-
Lithell, H.O.1
McKeigue, P.M.2
Berglund, L.3
Mohsen, R.4
Lithell, U.-B.5
-
223
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
-
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A: Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75: 59-72, 1993.
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Liu, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
224
-
-
0029992903
-
The human intron-containing gene for glycogenin maps to chromosome 3, band q24
-
Lomako J, Mazuruk K, Lomako WM, Alonso MD, Whelan WJ, Rodriguez IR: The human intron-containing gene for glycogenin maps to chromosome 3, band q24. Genomics 33: 519-22, 1996.
-
(1996)
Genomics
, vol.33
, pp. 519-522
-
-
Lomako, J.1
Mazuruk, K.2
Lomako, W.M.3
Alonso, M.D.4
Whelan, W.J.5
Rodriguez, I.R.6
-
225
-
-
0035041250
-
Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats
-
Lynn FC, Pamir N, Ng EH, McIntosh CH, Kieffer TJ, Pederson RA: Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats. Diabetes 50: 1004-11, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 1004-1011
-
-
Lynn, F.C.1
Pamir, N.2
Ng, E.H.3
McIntosh, C.H.4
Kieffer, T.J.5
Pederson, R.A.6
-
226
-
-
0032742985
-
Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes
-
Macfarlane WM, Frayling TM, Ellard S, Evans JC, Allen LIS, Bulman MP, Ayres S, Shepherd M, Clark P, Millward A, Demaine A, Wilkin T, Docherty K, Hattersley AT: Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes. J Clin Invest 104: R33-39, 1999.
-
(1999)
J Clin Invest
, vol.104
-
-
Macfarlane, W.M.1
Frayling, T.M.2
Ellard, S.3
Evans, J.C.4
Allen, L.I.S.5
Bulman, M.P.6
Ayres, S.7
Shepherd, M.8
Clark, P.9
Millward, A.10
Demaine, A.11
Wilkin, T.12
Docherty, K.13
Hattersley, A.T.14
-
227
-
-
0033540037
-
Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
-
Maechler P, Wollheim CB: Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. Nature 402: 685-9, 1999.
-
(1999)
Nature
, vol.402
, pp. 685-689
-
-
Maechler, P.1
Wollheim, C.B.2
-
228
-
-
0032987981
-
The 3′-untranslated region polymorphism of the gene for skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in the type 2 diabetic Japanese population
-
Maegawa H, Shi K, Hidaka H, Iwai N, Nishio Y, Egawa K, Kojima H, Haneda M, Yasuda H, Nakamura Y, Kinoshita M, Kikkawa R, Kashiwagi A: The 3′-untranslated region polymorphism of the gene for skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in the type 2 diabetic Japanese population. Diabetes 48: 1469-72, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1469-1472
-
-
Maegawa, H.1
Shi, K.2
Hidaka, H.3
Iwai, N.4
Nishio, Y.5
Egawa, K.6
Kojima, H.7
Haneda, M.8
Yasuda, H.9
Nakamura, Y.10
Kinoshita, M.11
Kikkawa, R.12
Kashiwagi, A.13
-
229
-
-
16044374799
-
Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families
-
Mahtani MM, Widén E, Lehto M et al.: Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families. Nature Gen. 14; 1: 90-94, 1996.
-
(1996)
Nature Gen
, vol.14
, Issue.1
, pp. 90-94
-
-
Mahtani, M.M.1
Widén, E.2
Lehto, M.3
-
230
-
-
0032700272
-
Mutations in NEUROD1 are associated with the development of type 2 diabetes
-
Malecki MT, Jhala U, Antonellis A, Fields L, Doria A, Orban T, Saad M, Warram JH, Montminy, M, Krolewski AS: Mutations in NEUROD1 are associated with the development of type 2 diabetes. Nature Genetics 23: 323-328, 1999.
-
(1999)
Nature Genetics
, vol.23
, pp. 323-328
-
-
Malecki, M.T.1
Jhala, U.2
Antonellis, A.3
Fields, L.4
Doria, A.5
Orban, T.6
Saad, M.7
Warram, J.H.8
Montminy, M.9
Krolewski, A.S.10
-
231
-
-
0034641849
-
Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes
-
Mammarella S, Romano F, Di Valerio A, Creati B, Esposito DL, Palmirotta R, Capani F, Volpe G, Battista P, Della Loggia F, Mariani-Constantini R, Cama A: Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes. Hum Mol Genet 17: 2517-21, 2000.
-
(2000)
Hum Mol Genet
, vol.17
, pp. 2517-2521
-
-
Mammarella, S.1
Romano, F.2
Di Valerio, A.3
Creati, B.4
Esposito, D.L.5
Palmirotta, R.6
Capani, F.7
Volpe, G.8
Battista, P.9
Della Loggia, F.10
Mariani-Constantini, R.11
Cama, A.12
-
232
-
-
0033060302
-
Pro12Ala substitution in the peroxisome proliferator-activated receptor-γ is not associated with type 2 diabetes
-
Mancini FP, Vaccaro O, Sabatino L, Tufano A, Rivellese AA, Riccardi G, Colantuoni V: Pro12Ala substitution in the peroxisome proliferator-activated receptor-γ is not associated with type 2 diabetes. Diabetes 48: 1466-8, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1466-1468
-
-
Mancini, F.P.1
Vaccaro, O.2
Sabatino, L.3
Tufano, A.4
Rivellese, A.A.5
Riccardi, G.6
Colantuoni, V.7
-
233
-
-
17444444715
-
Abnormal coupling of the insulin receptor binding in non-insulin-dependent diabetes
-
Mandarino LJ, Cambell PJ, Gottesman IS, Gerich JE: Abnormal coupling of the insulin receptor binding in non-insulin-dependent diabetes. Am J Physiol 247: E688-92, 1984.
-
(1984)
Am J Physiol
, vol.247
-
-
Mandarino, L.J.1
Cambell, P.J.2
Gottesman, I.S.3
Gerich, J.E.4
-
234
-
-
0026793446
-
Role of glucose and insulin resistance in the development of type 2 diabetes mellitus: Results of a 25 year follow-up study
-
Martin BC, Warran JH, Krolewski AS, Bergman RN, Soeldner J, Kahn CR: Role of glucose and insulin resistance in the development of type 2 diabetes mellitus: results of a 25 year follow-up study. Lancet 340: 925-929, 1992.
-
(1992)
Lancet
, vol.340
, pp. 925-929
-
-
Martin, B.C.1
Warran, J.H.2
Krolewski, A.S.3
Bergman, R.N.4
Soeldner, J.5
Kahn, C.R.6
-
235
-
-
0034931529
-
Isolation and characterisation of the human akt1 gene, identification of 13 single nucleotide polymorphism (SNPs) and lack of association with type II (non-insulin dependent) diabetes mellitus
-
Matsubara A, Wasson JC, Donelan SS, Welling CM, Glaser B, Permutt MA: Isolation and characterisation of the human akt1 gene, identification of 13 single nucleotide polymorphism (SNPs) and lack of association with type II (non-insulin dependent) diabetes mellitus. Diabetologia 44: 910-13, 2001.
-
(2001)
Diabetologia
, vol.44
, pp. 910-913
-
-
Matsubara, A.1
Wasson, J.C.2
Donelan, S.S.3
Welling, C.M.4
Glaser, B.5
Permutt, M.A.6
-
236
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudensji AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-19, 1985.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudensji, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
237
-
-
0006151390
-
Specific inhibition of PTEN expression with antisense oligonucleotide normalizes plasma glucose in db/db mice
-
Mckay RA, Butler M, Popoff IJ et al. (2000) Specific inhibition of PTEN expression with antisense oligonucleotide normalizes plasma glucose in db/db mice. Diabetes supplement 1; 207-OR.
-
(2000)
Diabetes
, Issue.SUPPL. 1
-
-
Mckay, R.A.1
Butler, M.2
Popoff, I.J.3
-
238
-
-
0031783161
-
Glucose tolerance and resistance to insulin-stimulated glucose uptake in men aged 70 years in relation to size at birth
-
McKeigue PM, Lithell H, Leon DA: Glucose tolerance and resistance to insulin-stimulated glucose uptake in men aged 70 years in relation to size at birth. Diabetologia 41: 1133-1138, 1998.
-
(1998)
Diabetologia
, vol.41
, pp. 1133-1138
-
-
McKeigue, P.M.1
Lithell, H.2
Leon, D.A.3
-
239
-
-
0033636523
-
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
-
Michael MD, Kulkami RN, Postic C, Previs SF, Shulman GI, Magnuson MA, Kahn CR: Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Moll Cell 6: 87-97, 2000.
-
(2000)
Moll Cell
, vol.6
, pp. 87-97
-
-
Michael, M.D.1
Kulkami, R.N.2
Postic, C.3
Previs, S.F.4
Shulman, G.I.5
Magnuson, M.A.6
Kahn, C.R.7
-
240
-
-
0032739288
-
Identifcation of a nuclear localization signal, RRMKWKK, in the homeodomain trasncription factor PDX-1
-
Moede T, Leibiger B, Pour HG, Berggren P Leibiger IB: Identifcation of a nuclear localization signal, RRMKWKK, in the homeodomain trasncription factor PDX-1. FEBS Lett 461: 229-34, 1999.
-
(1999)
FEBS Lett
, vol.461
, pp. 229-234
-
-
Moede, T.1
Leibiger, B.2
Pour, H.G.3
Berggren, P.4
Leibiger, I.B.5
-
241
-
-
0032567331
-
Characterization of human glycogenin-2, a self-glucosylating initiator of liver glycogen meatbolism
-
Mu J, Roach PJ: Characterization of human glycogenin-2, a self-glucosylating initiator of liver glycogen meatbolism. J Biol Chem 273: 34850-6, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 34850-34856
-
-
Mu, J.1
Roach, P.J.2
-
242
-
-
0031793698
-
Mutations in the hepatocyte nuclear factor-1alpha gene in Caucasian families originally classified as having Type I diabetes
-
Møller AM, Dalgaard LT, Pociot F, Nerup J, Hansen T, Pedersen O: Mutations in the hepatocyte nuclear factor-1alpha gene in Caucasian families originally classified as having Type I diabetes. Diabetologia 41: 1528-1531, 1998.
-
(1998)
Diabetologia
, vol.41
, pp. 1528-1531
-
-
Møller, A.M.1
Dalgaard, L.T.2
Pociot, F.3
Nerup, J.4
Hansen, T.5
Pedersen, O.6
-
243
-
-
0030886674
-
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in Beta2/NeuroD-deficient mice
-
Naya FJ, Huang H-P, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai M-J: Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in Beta2/NeuroD-deficient mice. Genes and Development 11, 18: 2323-2334, 1997.
-
(1997)
Genes and Development
, vol.11-18
, pp. 2323-2334
-
-
Naya, F.J.1
Huang, H.-P.2
Qiu, Y.3
Mutoh, H.4
DeMayo, F.J.5
Leiter, A.B.6
Tsai, M.-J.7
-
244
-
-
15644367096
-
A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism
-
Nestorowicz A, Inagaki N, Gonoi T, Schoor KP, Wilson BA, Glaser B, Landau H, Stanley CA, Thornton PS, Seino S, Permutt MA: A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism. Diabetes 46: 1743-1748, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1743-1748
-
-
Nestorowicz, A.1
Inagaki, N.2
Gonoi, T.3
Schoor, K.P.4
Wilson, B.A.5
Glaser, B.6
Landau, H.7
Stanley, C.A.8
Thornton, P.S.9
Seino, S.10
Permutt, M.A.11
-
245
-
-
0031802399
-
Genetic heterogeneity in familial hyperinsulinism
-
Nestorowicz A, Glaser B, Wilson BA, Shyng SL, Nichols CG, Stanley CA, Thornton PS, Permutt MA: Genetic heterogeneity in familial hyperinsulinism. Hum Mol Genet 7: 1119-1128, 1998.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1119-1128
-
-
Nestorowicz, A.1
Glaser, B.2
Wilson, B.A.3
Shyng, S.L.4
Nichols, C.G.5
Stanley, C.A.6
Thornton, P.S.7
Permutt, M.A.8
-
246
-
-
0023201498
-
Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins
-
Newman BJ, Selby JV, King MC, Slemenda C, Fabsitz R, Friedman GD: Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins. Diabetologia 30: 763-768, 1987.
-
(1987)
Diabetologia
, vol.30
, pp. 763-768
-
-
Newman, B.J.1
Selby, J.V.2
King, M.C.3
Slemenda, C.4
Fabsitz, R.5
Friedman, G.D.6
-
247
-
-
0031716242
-
Determinants for the progression from impaired glucose tolerance to non-insulin-dependent diabetes mellitus
-
Nijpels G: Determinants for the progression from impaired glucose tolerance to non-insulin-dependent diabetes mellitus. Eur J Clin Invest Suppl 2: 8-13, 1998.
-
(1998)
Eur J Clin Invest Suppl
, vol.2
, pp. 8-13
-
-
Nijpels, G.1
-
248
-
-
0030905313
-
Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes
-
Nikoulina SE, Ciaralda TP, Abrams-Carter L, Mudulair S, Park KS, Henry RR: Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes. Diabetes 46: 1017-1024, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1017-1024
-
-
Nikoulina, S.E.1
Ciaralda, T.P.2
Abrams-Carter, L.3
Mudulair, S.4
Park, K.S.5
Henry, R.R.6
-
249
-
-
0033958644
-
Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes
-
Nikoulina SE, Ciaraldi TP, Mudaliar S, Mohideen P, Carter L, Henry RR: Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes. Diabetes 49: 263-71, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 263-271
-
-
Nikoulina, S.E.1
Ciaraldi, T.P.2
Mudaliar, S.3
Mohideen, P.4
Carter, L.5
Henry, R.R.6
-
250
-
-
0033995047
-
Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen
-
O'Doherty RM, Jensen PB, Anderson P, Jones JG, Berman HK, Kearney D, Newgard CB: Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen. J Clin Invest 105: 479-488, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 479-488
-
-
O'Doherty, R.M.1
Jensen, P.B.2
Anderson, P.3
Jones, J.G.4
Berman, H.K.5
Kearney, D.6
Newgard, C.B.7
-
252
-
-
0031915309
-
Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM
-
Ohta Y, Tanizawa Y, Inoue H, Hosaka T, Ueda K, Matsutani A, Repunte VP, Yamada M, Kurachi Y, Bryan J, Aguilar-Brian L, Permutt MA: Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM. Diabetes 47: 476-81, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 476-481
-
-
Ohta, Y.1
Tanizawa, Y.2
Inoue, H.3
Hosaka, T.4
Ueda, K.5
Matsutani, A.6
Repunte, V.P.7
Yamada, M.8
Kurachi, Y.9
Bryan, J.10
Aguilar-Brian, L.11
Permutt, M.A.12
-
253
-
-
0035135375
-
Variants of neurogenin 3 gene are not associated with type II diabetes in Japanese subjects
-
Okada T, Tobe K, Hara K, Kawaguchi Y, Ikegami H, Ito C, Kadowaki T: Variants of neurogenin 3 gene are not associated with type II diabetes in Japanese subjects. Diabetologia 44: 241-244, 2001.
-
(2001)
Diabetologia
, vol.44
, pp. 241-244
-
-
Okada, T.1
Tobe, K.2
Hara, K.3
Kawaguchi, Y.4
Ikegami, H.5
Ito, C.6
Kadowaki, T.7
-
254
-
-
0032982032
-
The insulin gene VNTR, type 2 diabetes and birth weight
-
Ong KKL, Phillips DI, Fall C, Poulton J, Bennet ST, Golding J, Todd JA, Dunger DB: The insulin gene VNTR, type 2 diabetes and birth weight. Nat Genet 21: 262-263, 1999.
-
(1999)
Nat Genet
, vol.21
, pp. 262-263
-
-
Ong, K.K.L.1
Phillips, D.I.2
Fall, C.3
Poulton, J.4
Bennet, S.T.5
Golding, J.6
Todd, J.A.7
Dunger, D.B.8
-
255
-
-
0023951171
-
Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
-
O'Rahilly S, Turne RC, Matthews DR: Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med 318: 1225-30, 1988.
-
(1988)
N Engl J Med
, vol.318
, pp. 1225-1230
-
-
O'Rahilly, S.1
Turne, R.C.2
Matthews, D.R.3
-
256
-
-
0025896884
-
Detection of mutations in the insulin receptor gene in non-insulin dependent diabetic patients by analysis of single-stranded conformation polymorphisms
-
O'Rahilly S, Choi WH, Patel P, Turner RC, Flier JS, Moller DE: Detection of mutations in the insulin receptor gene in non-insulin dependent diabetic patients by analysis of single-stranded conformation polymorphisms. Diabetes 40: 777-782, 1991.
-
(1991)
Diabetes
, vol.40
, pp. 777-782
-
-
O'Rahilly, S.1
Choi, W.H.2
Patel, P.3
Turner, R.C.4
Flier, J.S.5
Moller, D.E.6
-
257
-
-
0026578215
-
Insulin receptor and insulin-responsive glusose transporter (GLUT4) mutations and polymorphisms in a Welsh non-insulin dependent diabetic population
-
O'Rahilly S, Krook A, Bishop A, Rees A, Flier JS, Moller DE: Insulin receptor and insulin-responsive glusose transporter (GLUT4) mutations and polymorphisms in a Welsh non-insulin dependent diabetic population. Diabetologia 35: 486-489, 1992.
-
(1992)
Diabetologia
, vol.35
, pp. 486-489
-
-
O'Rahilly, S.1
Krook, A.2
Bishop, A.3
Rees, A.4
Flier, J.S.5
Moller, D.E.6
-
258
-
-
0028803333
-
Isolation and characterization of the human muscle glycogen synthase gene
-
Orho M, Nikula-Ijas P, Schalin-Jantti C, Permutt MA, Groop LC: Isolation and characterization of the human muscle glycogen synthase gene. Diabetes 44: 1099-105, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 1099-1105
-
-
Orho, M.1
Nikula-Ijas, P.2
Schalin-Jantti, C.3
Permutt, M.A.4
Groop, L.C.5
-
259
-
-
0032993916
-
Expression of naturally occurring variants in the muscle glycogen synthase gene
-
Orho-Melander M, Shimomura H, Sanke T, Rasmussen SK, Nanjo K, Pedersen O, Groop LC: Expression of naturally occurring variants in the muscle glycogen synthase gene. Diabetes 48: 918-20, 1999a.
-
(1999)
Diabetes
, vol.48
, pp. 918-920
-
-
Orho-Melander, M.1
Shimomura, H.2
Sanke, T.3
Rasmussen, S.K.4
Nanjo, K.5
Pedersen, O.6
Groop, L.C.7
-
260
-
-
0032868004
-
A paired-sibling analysis of the XbaI polymorphism in the muscle glycoden synthase gene
-
Orho-Melander M, Almgren P, Kanninnen T, Forsblom C, Groop LC: A paired-sibling analysis of the XbaI polymorphism in the muscle glycoden synthase gene. Diabetologia 42: 1138-1145, 1999b.
-
(1999)
Diabetologia
, vol.42
, pp. 1138-1145
-
-
Orho-Melander, M.1
Almgren, P.2
Kanninnen, T.3
Forsblom, C.4
Groop, L.C.5
-
261
-
-
0026906885
-
Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness
-
van den Ouweland JM, Lemkes HH, Ruitenbeek W, Sandkuijl LA, de Vijlder MF, Struyvenberg PA, van de Kamp JJ, Maassen JA: Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat Genet 1: 368-71, 1992.
-
(1992)
Nat Genet
, vol.1
, pp. 368-371
-
-
Van Den Ouweland, J.M.1
Lemkes, H.H.2
Ruitenbeek, W.3
Sandkuijl, L.A.4
De Vijlder, M.F.5
Struyvenberg, P.A.6
Van De Kamp, J.J.7
Maassen, J.A.8
-
262
-
-
0032976998
-
Functional and morphological abnormalities of mitochondria harbouring the tRNA(Leu)(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease
-
van den Ouweland JM, Maechler P, Wollheim CB, Attardi G, Maassen JA: Functional and morphological abnormalities of mitochondria harbouring the tRNA(Leu)(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease. Diabetologia 42: 482-495, 1999.
-
(1999)
Diabetologia
, vol.42
, pp. 482-495
-
-
Van Den Ouweland, J.M.1
Maechler, P.2
Wollheim, C.B.3
Attardi, G.4
Maassen, J.A.5
-
263
-
-
0030952822
-
Analysis of candidate genes for susceptibility to type I diabetes: A case-control and a family-association study of genes on chromosome 2q31-35
-
Owerbach D, Naya F J, Tsai M-J, Allander SV, Powell DR, Gabbay KH: Analysis of candidate genes for susceptibility to type I diabetes: a case-control and a family-association study of genes on chromosome 2q31-35. Diabetes 46: 1069-1074, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1069-1074
-
-
Owerbach, D.1
Naya, F.J.2
Tsai, M.-J.3
Allander, S.V.4
Powell, D.R.5
Gabbay, K.H.6
-
265
-
-
0034700456
-
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice
-
Pende M, Kozma SC, Jaquet M, Oorschot V, Burcelin R, Le Marchand-Brustel Y, Klumperman J, Thorens B, Thomas G: Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice. Nature 408: 494-97, 2000.
-
(2000)
Nature
, vol.408
, pp. 494-497
-
-
Pende, M.1
Kozma, S.C.2
Jaquet, M.3
Oorschot, V.4
Burcelin, R.5
Le Marchand-Brustel, Y.6
Klumperman, J.7
Thorens, B.8
Thomas, G.9
-
266
-
-
0033614439
-
Protein targeting to glycogen/PPP1R5: Screening of coding and flanking genomic regions for polymorphisms and association analysis with insulin action in Pima Indians
-
Permana PA, Luczy-Bachman G, Bogardus C: Protein targeting to glycogen/PPP1R5: screening of coding and flanking genomic regions for polymorphisms and association analysis with insulin action in Pima Indians. Biochem Biophys Res Commun 258: 184-186, 1999.
-
(1999)
Biochem Biophys Res Commun
, vol.258
, pp. 184-186
-
-
Permana, P.A.1
Luczy-Bachman, G.2
Bogardus, C.3
-
267
-
-
0033910405
-
Functional analyses of amino acid substitutions Arg883Ser and Asp905Tyr of protein phosphatase-1 G-subunit
-
Permana PA, Kahn BB, Huppertz C, Mott DM: Functional analyses of amino acid substitutions Arg883Ser and Asp905Tyr of protein phosphatase-1 G-subunit. Mol Genet Metab 79: 151-158, 2000.
-
(2000)
Mol Genet Metab
, vol.79
, pp. 151-158
-
-
Permana, P.A.1
Kahn, B.B.2
Huppertz, C.3
Mott, D.M.4
-
268
-
-
0035119822
-
A genome scan for type 2 diabetes susceptibility loci in a genetically isolated population
-
Permutt MA, Wasson JC, Suarez BK, Lin J, Thomas J, Meyer J, Lewitzky S, Rennich JS, Parker A, DuPrat L, Maruti S, Chayen S, Glaser B: A genome scan for type 2 diabetes susceptibility loci in a genetically isolated population. Diabetes 50: 681-85, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 681-685
-
-
Permutt, M.A.1
Wasson, J.C.2
Suarez, B.K.3
Lin, J.4
Thomas, J.5
Meyer, J.6
Lewitzky, S.7
Rennich, J.S.8
Parker, A.9
DuPrat, L.10
Maruti, S.11
Chayen, S.12
Glaser, B.13
-
269
-
-
0030941820
-
Metabolic defects in lean nondiabetic offspring of NIDDM patients
-
Perseghin G, Ghosh S, Gerow K, Shulman GI: Metabolic defects in lean nondiabetic offspring of NIDDM patients. Diabetes 46: 1001-1009, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 1001-1009
-
-
Perseghin, G.1
Ghosh, S.2
Gerow, K.3
Shulman, G.I.4
-
270
-
-
0032857338
-
A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance
-
Pizzuti A, Frittitta L, Argiolas A, Baratta R, Goldfine LD, Bozzali M, Ercolino T, Scarlato G, Iacoviello L, Vignieri R, Tassi V, Triscitta V: A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance. Diabetes 48: 1881-85, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1881-1885
-
-
Pizzuti, A.1
Frittitta, L.2
Argiolas, A.3
Baratta, R.4
Goldfine, L.D.5
Bozzali, M.6
Ercolino, T.7
Scarlato, G.8
Iacoviello, L.9
Vignieri, R.10
Tassi, V.11
Triscitta, V.12
-
271
-
-
18144452590
-
Defective insulin secretion in hepatocyte nuclear factor 1 alpha-deficient mice
-
Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, Doyen A, Pick A J,
-
(1998)
J Clin Invest
, vol.101
, pp. 2215-2221
-
-
Pontoglio, M.1
Sreenan, S.2
Roe, M.3
Pugh, W.4
Ostrega, D.5
Doyen, A.6
Pick, A.J.7
Baldwin, A.8
Velho, G.9
Froguel, P.10
Levisetti, M.11
Bonner-Weir, S.12
Bell, G.I.13
Yaniv, M.14
Polonsky, K.S.15
-
272
-
-
0032587076
-
The Gly972>Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells
-
Porzio O, Federici M, Hribal ML, Lauro D, Accili D, Lauro R, Borboni P, Sesti G: The Gly972>Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells. J Clin Invest 104: 357-364, 1999.
-
(1999)
J Clin Invest
, vol.104
, pp. 357-364
-
-
Porzio, O.1
Federici, M.2
Hribal, M.L.3
Lauro, D.4
Accili, D.5
Lauro, R.6
Borboni, P.7
Sesti, G.8
-
273
-
-
0030980023
-
Low birth-weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs
-
Poulsen P, Vaag A, Kyvik K, Møller Jensen D, Beck-Nielsen H: Low birth-weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs. Diabetologia 40: 439-44, 1997.
-
(1997)
Diabetologia
, vol.40
, pp. 439-444
-
-
Poulsen, P.1
Vaag, A.2
Kyvik, K.3
Møller Jensen, D.4
Beck-Nielsen, H.5
-
274
-
-
0032953097
-
Heritability of type II (noninsulin-dependent) diabetes mellitus and abnormal glucose-tolerance: A population-based twin study
-
Poulsen P, Kyvik KO, Vaag A, Beck-Nielsen H: Heritability of type II (noninsulin-dependent) diabetes mellitus and abnormal glucose-tolerance: a population-based twin study. Diabetologia 42: 139-45, 1999.
-
(1999)
Diabetologia
, vol.42
, pp. 139-145
-
-
Poulsen, P.1
Kyvik, K.O.2
Vaag, A.3
Beck-Nielsen, H.4
-
275
-
-
0030614364
-
PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism
-
Printen JA, Brady M J, Saltiel AR: PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism. Science 275: 1475-1478, 1997.
-
(1997)
Science
, vol.275
, pp. 1475-1478
-
-
Printen, J.A.1
Brady, M.J.2
Saltiel, A.R.3
-
276
-
-
0028927487
-
Molecular and linkage analysis of type-I protein phosphatase catalytic beta-subunit gene: Lack of evidence for its major role in insulin resistance in Pima Indians
-
Prochazka M, Mochizuki H, Baier LJ, Cohen PT, Bogardus C: Molecular and linkage analysis of type-I protein phosphatase catalytic beta-subunit gene: lack of evidence for its major role in insulin resistance in Pima Indians. Diabetologia 38: 461-66, 1995.
-
(1995)
Diabetologia
, vol.38
, pp. 461-466
-
-
Prochazka, M.1
Mochizuki, H.2
Baier, L.J.3
Cohen, P.T.4
Bogardus, C.5
-
277
-
-
0033304957
-
Effect of an Asp905Tyr mutation of the glycogen-associated regulatory subunit of protein phosphatase-1 on the regulation of glycogen synthesis by insulin and cyclic adenosine 3′, 5′-monophosphate agonists
-
Ragolia L, Duddy N, Begum N: Effect of an Asp905Tyr mutation of the glycogen-associated regulatory subunit of protein phosphatase-1 on the regulation of glycogen synthesis by insulin and cyclic adenosine 3′, 5′-monophosphate agonists. Mol Endocrinol 13: 1773-83, 1999.
-
(1999)
Mol Endocrinol
, vol.13
, pp. 1773-1783
-
-
Ragolia, L.1
Duddy, N.2
Begum, N.3
-
278
-
-
0013844340
-
The glucose fatty acid cycle in obesity and maturity onset diabetes mellitus
-
Randle PJ, Garland PB, Newsholme EA, Hales CN: The glucose fatty acid cycle in obesity and maturity onset diabetes mellitus. Ann NY Acad Sci 131: 324-333, 1965.
-
(1965)
Ann NY Acad Sci
, vol.131
, pp. 324-333
-
-
Randle, P.J.1
Garland, P.B.2
Newsholme, E.A.3
Hales, C.N.4
-
279
-
-
0032452225
-
Regulatory interactions between lipids and carbohydrates: The glucose fatty acid cycle after 35 years
-
Randle PJ: Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years. Diabetes Metab Rev 14: 263-83, 1998.
-
(1998)
Diabetes Metab Rev
, vol.14
, pp. 263-283
-
-
Randle, P.J.1
-
280
-
-
0032937751
-
Loss of Cdk4 expression causes insulin deficient diabetes and Cdk4 activation results in β-cell hyperplasia
-
Rane SG, Dubus P, Mettus RV, Galbreath EJ, Boden G, Reddy EP, Barbacid M: Loss of Cdk4 expression causes insulin deficient diabetes and Cdk4 activation results in β-cell hyperplasia. Nature Genetics 22: 44-52, 1999.
-
(1999)
Nature Genetics
, vol.22
, pp. 44-52
-
-
Rane, S.G.1
Dubus, P.2
Mettus, R.V.3
Galbreath, E.J.4
Boden, G.5
Reddy, E.P.6
Barbacid, M.7
-
281
-
-
0034089587
-
Adenovirus-mediated expression of a naturally occurring Asp905Tyr variant of the glycogen-associated regulatory subunit of protein phosphatase-1 in L6 myotubes
-
Rasmussen SK, Hansen L, Frevert EU, Cohen PT, Kahn BB, Pedersen O: Adenovirus-mediated expression of a naturally occurring Asp905Tyr variant of the glycogen-associated regulatory subunit of protein phosphatase-1 in L6 myotubes. Diabetologia 43: 718-22, 2000a.
-
(2000)
Diabetologia
, vol.43
, pp. 718-722
-
-
Rasmussen, S.K.1
Hansen, L.2
Frevert, E.U.3
Cohen, P.T.4
Kahn, B.B.5
Pedersen, O.6
-
282
-
-
0033850381
-
The K121Q varaint of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians
-
Rasmussen SK, Urhammer SA, Pizzuti A, Echwald SM, Ekstrøm CT, Hansen L, Hansen T, Borch-Johnsen K, frittitta L, Trischitta V, Pedersen O: The K121Q varaint of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians. Diabetes 49: 1608-11, 2000b.
-
(2000)
Diabetes
, vol.49
, pp. 1608-1611
-
-
Rasmussen, S.K.1
Urhammer, S.A.2
Pizzuti, A.3
Echwald, S.M.4
Ekstrøm, C.T.5
Hansen, L.6
Hansen, T.7
Borch-Johnsen, K.8
Frittitta, L.9
Trischitta, V.10
Pedersen, O.11
-
283
-
-
0033782128
-
Mutations in the Insulin promoter factor-1 gene in late-onset type diabetes mellitus
-
Reis AF, Ye W-Z, Dubois-Laforgue D, Bellanné-Chantelot C, Timsit J, Velho G: Mutations in the Insulin promoter factor-1 gene in late-onset type diabetes mellitus. Eur J Endocrin 143: 511-13, 2000.
-
(2000)
Eur J Endocrin
, vol.143
, pp. 511-513
-
-
Reis, A.F.1
Ye, W.-Z.2
Dubois-Laforgue, D.3
Bellanné-Chantelot, C.4
Timsit, J.5
Velho, G.6
-
284
-
-
0025094344
-
Mapping genes in Diabetes
-
Rich SS: Mapping genes in Diabetes. Diabetes 39: 1319-1323, 1990.
-
(1990)
Diabetes
, vol.39
, pp. 1319-1323
-
-
Rich, S.S.1
-
285
-
-
0033803582
-
Variants in the hepatocyte nuclear factor-1α and -4α genes in Finnish and Chinese subjects with late-onset type 2 diabetes
-
Rissanen J, Wang H, Miettinen R, Kärkkäinen P, Kekäläinen P, Mykkänen L, Kuusisto J, Karhapää P, Niskanen L, Uusitupa M, Laakso M: Variants in the hepatocyte nuclear factor-1α and -4α genes in Finnish and Chinese subjects with late-onset type 2 diabetes. Diabetes Care 23: 1533-38, 2000.
-
(2000)
Diabetes Care
, vol.23
, pp. 1533-1538
-
-
Rissanen, J.1
Wang, H.2
Miettinen, R.3
Kärkkäinen, P.4
Kekäläinen, P.5
Mykkänen, L.6
Kuusisto, J.7
Karhapää, P.8
Niskanen, L.9
Uusitupa, M.10
Laakso, M.11
-
286
-
-
0031919090
-
An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedrich's ataxia) gene
-
Ristow M, Giannakidou E, Hebinck J, Busch K, Vorgerd M, Kotzka J, Knebel B, Mueller-Berghaus J, Epplen C, Pfeiffer A, Kahn CR, Doria A, Krone W, Mueller-Wieland D: An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedrich's ataxia) gene. Diabetes 47: 851-854, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 851-854
-
-
Ristow, M.1
Giannakidou, E.2
Hebinck, J.3
Busch, K.4
Vorgerd, M.5
Kotzka, J.6
Knebel, B.7
Mueller-Berghaus, J.8
Epplen, C.9
Pfeiffer, A.10
Kahn, C.R.11
Doria, A.12
Krone, W.13
Mueller-Wieland, D.14
-
287
-
-
0027138261
-
Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation
-
Rosetti L, and Hu M: Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. J Clin Invest 92: 2963-2974, 1993.
-
(1993)
J Clin Invest
, vol.92
, pp. 2963-2974
-
-
Rosetti, L.1
Hu, M.2
-
288
-
-
0028809238
-
Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin dependent diabetes mellitus
-
Rothman DL, Magnusson I, Cline G, Gerard D, Kahn CR, Shulman RG, Shulman GI: Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin dependent diabetes mellitus. Proc. Natl. Acad. Sci. 92: 983-987, 1995.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 983-987
-
-
Rothman, D.L.1
Magnusson, I.2
Cline, G.3
Gerard, D.4
Kahn, C.R.5
Shulman, R.G.6
Shulman, G.I.7
-
289
-
-
0030914931
-
Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas
-
St-Onge L, Sosa-Pineda B, Chowdhury K, Mansouri A, Gruss P: Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas. Nature 387: 406-9, 1997.
-
(1997)
Nature
, vol.387
, pp. 406-409
-
-
St-Onge, L.1
Sosa-Pineda, B.2
Chowdhury, K.3
Mansouri, A.4
Gruss, P.5
-
290
-
-
0029818742
-
Missense mutation of amylin gene (S20G) in Japanese NIDDM patients
-
Sakagashira S, Sanke T, Hanabusa T, Shimomura H, Ohagi S, Kumagaye KY, Nakajima K, Nanjo K: Missense mutation of amylin gene (S20G) in Japanese NIDDM patients. Diabetes 45: 1279-1281, 1996.
-
(1996)
Diabetes
, vol.45
, pp. 1279-1281
-
-
Sakagashira, S.1
Sanke, T.2
Hanabusa, T.3
Shimomura, H.4
Ohagi, S.5
Kumagaye, K.Y.6
Nakajima, K.7
Nanjo, K.8
-
291
-
-
0029561629
-
Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic β-cells, brain, heart and skeletal muscle
-
Sakura H, Ämmälä C, Smith PA, Gribble FM, Ashcroft FM: Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic β-cells, brain, heart and skeletal muscle. FEBS Lett 377: 338-344. 1995.
-
(1995)
FEBS Lett
, vol.377
, pp. 338-344
-
-
Sakura, H.1
Ämmälä, C.2
Smith, P.A.3
Gribble, F.M.4
Ashcroft, F.M.5
-
292
-
-
0029066625
-
Characterization and variation of a human inwardly-rectifying K-channel gene (KCNJ6): A putative ATP-sensitive K-channel subunit
-
Sakura H, Bond C, Warren-Perry M et al: Characterization and variation of a human inwardly-rectifying K-channel gene (KCNJ6): A putative ATP-sensitive K-channel subunit. FEBS Lett 367: 193-197, 1995.
-
(1995)
FEBS Lett
, vol.367
, pp. 193-197
-
-
Sakura, H.1
Bond, C.2
Warren-Perry, M.3
-
293
-
-
0029740428
-
Sequence variations in th human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: No association with NIDDM in white Caucasian subjects or evidence of of abnormal function when expressed in vitro
-
Sakura H, Wat N, Horton V, Millns H, Turner RC, Aschcroft FM: Sequence variations in th human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in white Caucasian subjects or evidence of of abnormal function when expressed in vitro. Diabetologia 39: 1233-6,1996.
-
(1996)
Diabetologia
, vol.39
, pp. 1233-1236
-
-
Sakura, H.1
Wat, N.2
Horton, V.3
Millns, H.4
Turner, R.C.5
Aschcroft, F.M.6
-
294
-
-
0026636946
-
Impaired activation of glycogen synthase in people at risk for developing NIDDM
-
Schalin-Jantti C, Harkonen M, Groop LC: Impaired activation of glycogen synthase in people at risk for developing NIDDM. Diabetes 41: 598-604, 1992.
-
(1992)
Diabetes
, vol.41
, pp. 598-604
-
-
Schalin-Jantti, C.1
Harkonen, M.2
Groop, L.C.3
-
296
-
-
0025067390
-
Human insulin receptor gene: Partial sequence and amplifications of exons by the polymerase chain reaction
-
Seino S, Seino M, Bell GI: Human insulin receptor gene: partial sequence and amplifications of exons by the polymerase chain reaction. Diabetes 39: 123-128, 1990.
-
(1990)
Diabetes
, vol.39
, pp. 123-128
-
-
Seino, S.1
Seino, M.2
Bell, G.I.3
-
297
-
-
0028981182
-
An extended transmission/disequilibrium test (TDT) for multi-allele marker loci
-
Sham PC, Curtis D: An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Am. J. Hum. Genet. 59: 323-336, 1995.
-
(1995)
Am J Hum Genet
, vol.59
, pp. 323-336
-
-
Sham, P.C.1
Curtis, D.2
-
298
-
-
0032540944
-
Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action
-
Sharma PM, Egawa K, Huang Y, Martin JL, Huvar I, Boss GR, Olefsky JM: Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action. J Biol Chem 273: 18528-37, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 18528-18537
-
-
Sharma, P.M.1
Egawa, K.2
Huang, Y.3
Martin, J.L.4
Huvar, I.5
Boss, G.R.6
Olefsky, J.M.7
-
299
-
-
0031713870
-
Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q
-
Shaw JT, Lovelock PK, Kesting JB, Cardinal J, Duffy D, Wainwright B, Cameron DP: Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q. Diabetes 47: 1793-96, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 1793-1796
-
-
Shaw, J.T.1
Lovelock, P.K.2
Kesting, J.B.3
Cardinal, J.4
Duffy, D.5
Wainwright, B.6
Cameron, D.P.7
-
300
-
-
0030818679
-
Asp905Tyr polymorphism of protein phosphatase 1 G subunit gene in hypertension
-
Shen GQ, Ikegami H, Fujisawa T, Hamada Y, Kamide K, Rakugi H, Higaki J, Murakami H, Shimamoto K, Ogihara T: Asp905Tyr polymorphism of protein phosphatase 1 G subunit gene in hypertension. Hypertension 30: 236-239, 1997.
-
(1997)
Hypertension
, vol.30
, pp. 236-239
-
-
Shen, G.Q.1
Ikegami, H.2
Fujisawa, T.3
Hamada, Y.4
Kamide, K.5
Rakugi, H.6
Higaki, J.7
Murakami, H.8
Shimamoto, K.9
Ogihara, T.10
-
301
-
-
0031819689
-
Asp905Tyr polymorphism of the gene for the skeletal muscle-specific glycogen-targeting subunit of protein phosphatase-1 in NIDDM
-
Shen GQ, Ikegami H, Kawaguchi Y, Fujisawa T, Hamada Y, Ueda H, Shintani M, Nojima K, Kawabata Y, Babaya N, Ogihara T: Asp905Tyr polymorphism of the gene for the skeletal muscle-specific glycogen-targeting subunit of protein phosphatase-1 in NIDDM. Diabetes Care 21: 1086-89, 1998.
-
(1998)
Diabetes Care
, vol.21
, pp. 1086-1089
-
-
Shen, G.Q.1
Ikegami, H.2
Kawaguchi, Y.3
Fujisawa, T.4
Hamada, Y.5
Ueda, H.6
Shintani, M.7
Nojima, K.8
Kawabata, Y.9
Babaya, N.10
Ogihara, T.11
-
302
-
-
0029348806
-
Protein phosphatase regulation by endogenous inhibitors
-
Shenolikar S: Protein phosphatase regulation by endogenous inhibitors. Semin. Cancer Biol. 6: 219-227, 1995.
-
(1995)
Semin Cancer Biol
, vol.6
, pp. 219-227
-
-
Shenolikar, S.1
-
303
-
-
0032143284
-
Phosphoinositide 3-kinase, the key switch mechanism in insulin signalling
-
Shepherd PR, Withers D J, Siddle K: Phosphoinositide 3-kinase, the key switch mechanism in insulin signalling. Biochem. J. 333 (Pt3): 471-490, 1998.
-
(1998)
Biochem J
, vol.333
, Issue.PART 3
, pp. 471-490
-
-
Shepherd, P.R.1
Withers, D.J.2
Siddle, K.3
-
304
-
-
0030798067
-
A missense mutation of the muscle glycogen synthase gene (M41 6V) is associated with insulin resistance in the Japanese population
-
Shimomura H, sanke T, Ueda K, Hanabusa T, Sakagashira S, nanjo K: A missense mutation of the muscle glycogen synthase gene (M41 6V) is associated with insulin resistance in the Japanese population. Diabetologia 40: 947-52, 1997.
-
(1997)
Diabetologia
, vol.40
, pp. 947-952
-
-
Shimomura, H.1
Sanke, T.2
Ueda, K.3
Hanabusa, T.4
Sakagashira, S.5
Nanjo, K.6
-
305
-
-
0033856122
-
Nonsense mutation of islet-1 gene (Q310X) in a type 2 diabetic patient with strong family history
-
Shimomura H, sanke T, Hanabusa T, Tsunoda K, Furuta H, Nanjo K: Nonsense mutation of islet-1 gene (Q310X) in a type 2 diabetic patient with strong family history. Diabetes 49: 1597-1600, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 1597-1600
-
-
Shimomura, H.1
Sanke, T.2
Hanabusa, T.3
Tsunoda, K.4
Furuta, H.5
Nanjo, K.6
-
307
-
-
0033762782
-
Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes
-
Silva JP, Köhler M, GraffC, Oldfors A, Magnuson MA, Berggren P-O, Larsson N-G: Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes. Nat Genet 26: 336-40, 2000.
-
(2000)
Nat Genet
, vol.26
, pp. 336-340
-
-
Silva, J.P.1
Köhler, M.2
Graff, C.3
Oldfors, A.4
Magnuson, M.A.5
Berggren, P.-O.6
Larsson, N.-G.7
-
308
-
-
0033499662
-
Paired-homeobox transcription factor pax4 acts as a transcriptional repressor in early pancreatic development
-
Smith SB, Ee HC, Conners JR, German MS: Paired-homeobox transcription factor pax4 acts as a transcriptional repressor in early pancreatic development. Moll Cell Biol 19: 8272-80, 1999.
-
(1999)
Moll Cell Biol
, vol.19
, pp. 8272-8280
-
-
Smith, S.B.1
Ee, H.C.2
Conners, J.R.3
German, M.S.4
-
309
-
-
0034711279
-
Autoregulation and maturity onset diabetes of the young transcription factors control the human Pax4 promoter
-
Smith SB, Watada H, Scheel DW, Mrejen C, German MS: Autoregulation and maturity onset diabetes of the young transcription factors control the human Pax4 promoter. J Biol Chem 275: 36910-19, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 36910-36919
-
-
Smith, S.B.1
Watada, H.2
Scheel, D.W.3
Mrejen, C.4
German, M.S.5
-
310
-
-
0030026603
-
Growth and endocrine function after near total pancreatectomy for hyperinsulinaemic hypoglycaemia
-
Soliman AT, Alsalmi I, Darwish A, Asfour MG: Growth and endocrine function after near total pancreatectomy for hyperinsulinaemic hypoglycaemia. Arch Dis Child 74: 379-385, 1996.
-
(1996)
Arch Dis Child
, vol.74
, pp. 379-385
-
-
Soliman, A.T.1
Alsalmi, I.2
Darwish, A.3
Asfour, M.G.4
-
311
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin dependent diabetes mellitus (IDDM)
-
Spielman RS, McGinnis RE, Ewens WJ: Transmission test for linkage disequilibrium: the insulin gene region and insulin dependent diabetes mellitus (IDDM). Am. J. Hum. Genet. 52: 506-516, 1993.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 506-516
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
312
-
-
0027960448
-
Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation
-
Stambolic V, Woodgett JR: Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation. Biochem J. 303: 701-704, 1994.
-
(1994)
Biochem J
, vol.303
, pp. 701-704
-
-
Stambolic, V.1
Woodgett, J.R.2
-
313
-
-
0032475861
-
Negative regulation of pkb/akt-dependent cell-survival by the tumor-suppressor pten
-
Stambolic V, Suzuki A, Delapompa JL et al: Negative regulation of pkb/akt-dependent cell-survival by the tumor-suppressor pten. Cell 95: 29-39, 1998.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
Delapompa, J.L.3
-
314
-
-
0032493123
-
Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene
-
Stanley CA, Lieu YK, Hsu BY, Burlina AB, Greenberg CR, Hopwood NJ, Perlman K, Rich BH, Zammarich E, Poncz M: Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene. N Engl J Med 338: 1352-7, 1998.
-
(1998)
N Engl J Med
, vol.338
, pp. 1352-1357
-
-
Stanley, C.A.1
Lieu, Y.K.2
Hsu, B.Y.3
Burlina, A.B.4
Greenberg, C.R.5
Hopwood, N.J.6
Perlman, K.7
Rich, B.H.8
Zammarich, E.9
Poncz, M.10
-
315
-
-
17144436629
-
Identification of a candidate tumor-suppressor gene, mmac1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA et al. Identification of a candidate tumor-suppressor gene, mmac1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 15: 356-362, 1997.
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
-
316
-
-
0028845528
-
Linkage studies in NIDDM patients with markers near the sulfonylurea receptor gene
-
Stirling B, Cox NJ, Bell GI, Hanis CL, Spielman RS, Concannon P: Linkage studies in NIDDM patients with markers near the sulfonylurea receptor gene. Diabetologia 38: 1479-1481, 1995.
-
(1995)
Diabetologia
, vol.38
, pp. 1479-1481
-
-
Stirling, B.1
Cox, N.J.2
Bell, G.I.3
Hanis, C.L.4
Spielman, R.S.5
Concannon, P.6
-
317
-
-
0030695445
-
The maturity-onset diabetes of the young (MODY1) transcription factor HNF 4alpha regulates expression of genes required for glucose transport and metabolism
-
Stoffel M, Duncan SA: The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci 94: 13209-14, 1997.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 13209-13214
-
-
Stoffel, M.1
Duncan, S.A.2
-
318
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF: Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nature Genetics 15: 106-110, 1997a.
-
(1997)
Nature Genetics
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
Clarke, W.L.4
Habener, J.F.5
-
319
-
-
0031253820
-
Ealy-onset type II diabetes mellitus (MODY4) linked to IPF1
-
Stoffers DA, Ferrer J, Clarke WL, Habener JF: Ealy-onset type II diabetes mellitus (MODY4) linked to IPF1. Nature genetics 17: 138-139, 1997b.
-
(1997)
Nature Genetics
, vol.17
, pp. 138-139
-
-
Stoffers, D.A.1
Ferrer, J.2
Clarke, W.L.3
Habener, J.F.4
-
320
-
-
0032128288
-
Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein
-
Stoffers DA, Stanojevic V, Habener JF: Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein. J Clin Invest 102: 232-241, 1998.
-
(1998)
J Clin Invest
, vol.102
, pp. 232-241
-
-
Stoffers, D.A.1
Stanojevic, V.2
Habener, J.F.3
-
321
-
-
0029933511
-
A variation at position -30 of the β-cell glucokinase promotor is associated with reduced β-cell function in middle-aged Japanese-American men
-
Stone LM, Kahn SE, Fujimoto WY, Deeb SS, Porte D Jr: A variation at position -30 of the β-cell glucokinase promotor is associated with reduced β-cell function in middle-aged Japanese-American men. Diabetes 46: 422-28, 1996.
-
(1996)
Diabetes
, vol.46
, pp. 422-428
-
-
Stone, L.M.1
Kahn, S.E.2
Fujimoto, W.Y.3
Deeb, S.S.4
Porte Jr., D.5
-
322
-
-
0035078748
-
The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans
-
Stumvoll M, Fritsche A, Volk A, Stefan N, Madaus A, Maerker E, Teigeler A, Koch M, Machicao F, Haring H: The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans. Diabetes 50: 882-885, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 882-885
-
-
Stumvoll, M.1
Fritsche, A.2
Volk, A.3
Stefan, N.4
Madaus, A.5
Maerker, E.6
Teigeler, A.7
Koch, M.8
Machicao, F.9
Haring, H.10
-
323
-
-
0032699475
-
Identification of novel non-insulin-dependent diabetes mellitus susceptibility loci in the Otsuka Long-Evans Tokoshima fatty rat by MQM-mapping method
-
Sugiura K, Miyake T, Taniguchi Y, Yamada T, Moralejo DH, Wei S, Wei K, Sasaki Y, Matsumoto K: Identification of novel non-insulin-dependent diabetes mellitus susceptibility loci in the Otsuka Long-Evans Tokoshima fatty rat by MQM-mapping method. Mamm Genome 12: 1126-31, 1999.
-
(1999)
Mamm Genome
, vol.12
, pp. 1126-1131
-
-
Sugiura, K.1
Miyake, T.2
Taniguchi, Y.3
Yamada, T.4
Moralejo, D.H.5
Wei, S.6
Wei, K.7
Sasaki, Y.8
Matsumoto, K.9
-
324
-
-
0033580912
-
The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism
-
Summers SA, Kao AW, Kohn AD, Backus GS, Roth RA, Pessin JE, Bimbaum MJ: The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism. J Biol Chem 274: 17934-40, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 17934-17940
-
-
Summers, S.A.1
Kao, A.W.2
Kohn, A.D.3
Backus, G.S.4
Roth, R.A.5
Pessin, J.E.6
Bimbaum, M.J.7
-
325
-
-
0021214244
-
Chronic hyperinsulinemia in the fetal rhesus monkey. Effects of physiological hyperinsulinemia on fetal growth and composition
-
Susa JB, Neave C, Sehgal P, Singer DB, Zeller WP, Schwartz R: Chronic hyperinsulinemia in the fetal rhesus monkey. Effects of physiological hyperinsulinemia on fetal growth and composition. Diabetes 33: 656-660, 1984.
-
(1984)
Diabetes
, vol.33
, pp. 656-660
-
-
Susa, J.B.1
Neave, C.2
Sehgal, P.3
Singer, D.B.4
Zeller, W.P.5
Schwartz, R.6
-
326
-
-
0031843386
-
Mice lacking the homeobox transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β-cells
-
Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubinstein JL, German MS: Mice lacking the homeobox transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β-cells. Development 125: 2213-21, 1998.
-
(1998)
Development
, vol.125
, pp. 2213-2221
-
-
Sussel, L.1
Kalamaras, J.2
Hartigan-O'Connor, D.J.3
Meneses, J.J.4
Pedersen, R.A.5
Rubinstein, J.L.6
German, M.S.7
-
327
-
-
0027515127
-
Inactivation of glycogen synthase kinase 3b by phosphorylation: New kinase connections in insulin and growth factor signaling
-
Sutherland C, Leighton IA, Cohen P: Inactivation of glycogen synthase kinase 3b by phosphorylation: New kinase connections in insulin and growth factor signaling. Biochem J 296: 15-19, 1993.
-
(1993)
Biochem J
, vol.296
, pp. 15-19
-
-
Sutherland, C.1
Leighton, I.A.2
Cohen, P.3
-
328
-
-
0032898857
-
The insulin signaling pathway
-
Taha C, Klip A: The insulin signaling pathway. J Membr Biol; 169(1): 1-12, 1999
-
(1999)
J Membr Biol
, vol.169
, Issue.1
, pp. 1-12
-
-
Taha, C.1
Klip, A.2
-
330
-
-
0029981205
-
A pancreatic islet inwardly rectifying potassium channel: cDNA cloning, determination of the genomic structure and genetic variations in Japanese NIDDM patients
-
Tanizawa Y, Matsubara A, Ueda K, Katagiri H, Kuwano A, Ferrer J, Permutt MA, Oka Y: A pancreatic islet inwardly rectifying potassium channel: cDNA cloning, determination of the genomic structure and genetic variations in Japanese NIDDM patients. Diabetologia 39: 447-452, 1996.
-
(1996)
Diabetologia
, vol.39
, pp. 447-452
-
-
Tanizawa, Y.1
Matsubara, A.2
Ueda, K.3
Katagiri, H.4
Kuwano, A.5
Ferrer, J.6
Permutt, M.A.7
Oka, Y.8
-
331
-
-
0016641270
-
A difference between the inheritance of classical juvenile-onset and maturity-onset type diabetes of young people
-
Tattersall RB, Fajans SS: A difference between the inheritance of classical juvenile-onset and maturity-onset type diabetes of young people. Diabetes 24: 44-55, 1975.
-
(1975)
Diabetes
, vol.24
, pp. 44-55
-
-
Tattersall, R.B.1
Fajans, S.S.2
-
332
-
-
0032469940
-
Syndromes associated with insulin resistance and acanthosis nigricans
-
Taylor SI and Arioglu E: Syndromes associated with insulin resistance and acanthosis nigricans. J Basic Clin Physiol Pharmacol 9: 419-439, 1998.
-
(1998)
J Basic Clin Physiol Pharmacol
, vol.9
, pp. 419-439
-
-
Taylor, S.I.1
Arioglu, E.2
-
333
-
-
0030961962
-
Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease
-
Terauchi Y, Iwamoto K, Tamemoto H, Komeda K, Ishii C, Kanazawa Y, Asanuma N, Aizawa T, Akanuma Y, Yasuda K, Kodama T, Tobe K, Yazaki Y, Kadowaki T: Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease. J Clin Invest 99: 861-866, 1997.
-
(1997)
J Clin Invest
, vol.99
, pp. 861-866
-
-
Terauchi, Y.1
Iwamoto, K.2
Tamemoto, H.3
Komeda, K.4
Ishii, C.5
Kanazawa, Y.6
Asanuma, N.7
Aizawa, T.8
Akanuma, Y.9
Yasuda, K.10
Kodama, T.11
Tobe, K.12
Yazaki, Y.13
Kadowaki, T.14
-
334
-
-
0032909703
-
Increased insulin sensitivity and hypoglycemia in mice lacking the p85α subunit of phosphoinositide 3-kinase
-
Terauchi Y, Tsuji Y, Satoh S, Minoura H, Murakami K, Okuno A, Inukai K, Asano T, Kaburagi Y, Ueki K, Nakajima H, Hanafusa T, Matsuzawa Y, Sekihara H, Yin Y, Barrett JC, Oda H, Ishikawa T, Akanuma Y, Komuro I, Suzuki M, Yamamura Y-I, Kodama T, Suzuki H, Koyasu S, Aizawa S, Tobe K, Fukui Y, Yazaki Y, kadowaki T: Increased insulin sensitivity and hypoglycemia in mice lacking the p85α subunit of phosphoinositide 3-kinase. Nature Genetics 21: 230-235, 1999.
-
(1999)
Nature Genetics
, vol.21
, pp. 230-235
-
-
Terauchi, Y.1
Tsuji, Y.2
Satoh, S.3
Minoura, H.4
Murakami, K.5
Okuno, A.6
Inukai, K.7
Asano, T.8
Kaburagi, Y.9
Ueki, K.10
Nakajima, H.11
Hanafusa, T.12
Matsuzawa, Y.13
Sekihara, H.14
Yin, Y.15
Barrett, J.C.16
Oda, H.17
Ishikawa, T.18
Akanuma, Y.19
Komuro, I.20
Suzuki, M.21
Yamamura, Y.-I.22
Kodama, T.23
Suzuki, H.24
Koyasu, S.25
Aizawa, S.26
Tobe, K.27
Fukui, Y.28
Yazaki, Y.29
Kadowaki, T.30
more..
-
335
-
-
0033970635
-
Insulin effect during embryo genesis determines fetal growth: A possible molecular link between birth weight and susceptibility to type 2 diabetes
-
Terauchi Y, Kubota N, Tamemoto H, Sakura H, Nagai R, Akanuma Y, Kimura S, Kadowaki T: Insulin effect during embryogenesis determines fetal growth: a possible molecular link between birth weight and susceptibility to type 2 diabetes. Diabetes 49: 82-86, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 82-86
-
-
Terauchi, Y.1
Kubota, N.2
Tamemoto, H.3
Sakura, H.4
Nagai, R.5
Akanuma, Y.6
Kimura, S.7
Kadowaki, T.8
-
336
-
-
0035220163
-
On the resolution and feasibility of genome scanning approaches
-
Terwilliger JD: On the resolution and feasibility of genome scanning approaches. Adv Genet 42: 351-91, 2001.
-
(2001)
Adv Genet
, vol.42
, pp. 351-391
-
-
Terwilliger, J.D.1
-
337
-
-
0345421089
-
The AKT1 gene, the human homologue of a retroviral oncogene, is located on chromosome 14 at band q32
-
Testa JR, Huebner K, Croce CM, Staal S: The AKT1 gene, the human homologue of a retroviral oncogene, is located on chromosome 14 at band q32. Cytogenet Cell Genet 40: 761, 1985.
-
(1985)
Cytogenet Cell Genet
, vol.40
, pp. 761
-
-
Testa, J.R.1
Huebner, K.2
Croce, C.M.3
Staal, S.4
-
338
-
-
0029021696
-
Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy
-
Thomas PM, Cote GJ, Wohllk N, Haddad B, Mathew PM, Rabl W, Aguilar-Bryan L, Gagel RF, Bryan J: Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science 268: 426-429, 1995.
-
(1995)
Science
, vol.268
, pp. 426-429
-
-
Thomas, P.M.1
Cote, G.J.2
Wohllk, N.3
Haddad, B.4
Mathew, P.M.5
Rabl, W.6
Aguilar-Bryan, L.7
Gagel, R.F.8
Bryan, J.9
-
339
-
-
0031438446
-
Genetic linkage study of a major susceptibility locus (D2S125) in a British population of non-insulin dependent diabetic sib-pairs using a simple nonisotopic screening method
-
Thomas AW, Sherrat EJ, Gagg JW, Davies SA, Majid A, Alcolado JC: Genetic linkage study of a major susceptibility locus (D2S125) in a British population of non-insulin dependent diabetic sib-pairs using a simple nonisotopic screening method. Hum Genet 101: 212-13, 1997.
-
(1997)
Hum Genet
, vol.101
, pp. 212-213
-
-
Thomas, A.W.1
Sherrat, E.J.2
Gagg, J.W.3
Davies, S.A.4
Majid, A.5
Alcolado, J.C.6
-
340
-
-
0029807640
-
Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action
-
Thompson BD, Pratley R, Ossowski V: Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action. J. Clin. Invest. 98; 10: 2346-2350, 1996.
-
(1996)
J Clin Invest
, vol.98
, Issue.10
, pp. 2346-2350
-
-
Thompson, B.D.1
Pratley, R.2
Ossowski, V.3
-
341
-
-
8044222127
-
Physiological and genetic characterization of the Gly 40Ser mutation in the glucagon receptor gene in the Sardinian population
-
The Sardinian Diabetes Genetic Study Group
-
Tonolo G, Melis MG, Ciccarese M, Secchi G, Atzeni MM, Maioli M, Pala G, Massida A, Manai M, Pilosu RM, Li LS, Luthman H, Maioli M: Physiological and genetic characterization of the Gly40Ser mutation in the glucagon receptor gene in the Sardinian population. The Sardinian Diabetes Genetic Study Group. Diabetologia 40: 89-94, 1997.
-
(1997)
Diabetologia
, vol.40
, pp. 89-94
-
-
Tonolo, G.1
Melis, M.G.2
Ciccarese, M.3
Secchi, G.4
Atzeni, M.M.5
Maioli, M.6
Pala, G.7
Massida, A.8
Manai, M.9
Pilosu, R.M.10
Li, L.S.11
Luthman, H.12
Maioli, M.13
-
342
-
-
0032525574
-
ATP channel inhibition by ATP
-
ATP channel inhibition by ATP. EMBO J 17: 3290-96, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 3290-3296
-
-
Tucker, S.J.1
Gribble, F.M.2
Proks, P.3
Trapp, S.4
Ryder, T.J.5
Haug, T.6
Reimann, F.7
Ashcroft, F.M.8
-
343
-
-
0030943465
-
A prevalent amin oacid polymorphism at codon 98 in the hepatocyte nuclear factor-1a is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge
-
Urhammer SA, Fridberg M, Hansen T, Rasmussen SK, Moller AM, Clausen JO, Pedersen O: A prevalent amin oacid polymorphism at codon 98 in the hepatocyte nuclear factor-1a is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge. Diabetes 46: 912-916, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 912-916
-
-
Urhammer, S.A.1
Fridberg, M.2
Hansen, T.3
Rasmussen, S.K.4
Moller, A.M.5
Clausen, J.O.6
Pedersen, O.7
-
344
-
-
0031159745
-
Studies of the impact of a liver glucokinase promoter variant on glucose tolerance and insulin sensitivity index
-
Urhammer SA, Hansen T, Jensen LB, Clausen JO, Hansen L, Chui KC, Pedersen O: Studies of the impact of a liver glucokinase promoter variant on glucose tolerance and insulin sensitivity index. J Clin Endocrinol Metab 82: 1786-89, 1997.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 1786-1789
-
-
Urhammer, S.A.1
Hansen, T.2
Jensen, L.B.3
Clausen, J.O.4
Hansen, L.5
Chui, K.C.6
Pedersen, O.7
-
345
-
-
0031852907
-
The g/a nucleotide variant at position -30 in the beta-cell-specific glucokinase gene promoter has no impact on the beta-cell function in Danish Caucasians
-
Urhammer SA, Hansen T, Clausen JO, Eiberg H, Pedersen O: The g/a nucleotide variant at position -30 in the beta-cell-specific glucokinase gene promoter has no impact on the beta-cell function in Danish Caucasians. Diabetes 47: 1359-61, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 1359-1361
-
-
Urhammer, S.A.1
Hansen, T.2
Clausen, J.O.3
Eiberg, H.4
Pedersen, O.5
-
346
-
-
0026575758
-
Decreased activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin dependent diabetes mellitus
-
Vaag A, Henriksen JE, Beck-Nielsen: Decreased activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin dependent diabetes mellitus. J. Clin. Invest. 89: 782-788, 1992.
-
(1992)
J Clin Invest
, vol.89
, pp. 782-788
-
-
Vaag, A.1
Henriksen, J.E.2
Beck-Nielsen3
-
347
-
-
0033063033
-
On the pathophysiology of late onset non-insulin dependent diabetes mellitus. Current controversies and new insights
-
Vaag A: On the pathophysiology of late onset non-insulin dependent diabetes mellitus. Current controversies and new insights. Dan Med Bull 46: 197-234, 1999.
-
(1999)
Dan Med Bull
, vol.46
, pp. 197-234
-
-
Vaag, A.1
-
348
-
-
0031018819
-
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
-
Vafiadis P, Bennet ST, Todd JA, Nadeau J, Grabs R, Goodyer CG, Wickramansinghe S, Colle E, Polychronakos C: Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nature Genetics 15: 289-292, 1997.
-
(1997)
Nature Genetics
, vol.15
, pp. 289-292
-
-
Vafiadis, P.1
Bennet, S.T.2
Todd, J.A.3
Nadeau, J.4
Grabs, R.5
Goodyer, C.G.6
Wickramansinghe, S.7
Colle, E.8
Polychronakos, C.9
-
349
-
-
0031436966
-
Human beta-2 receptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function
-
Valerie L, Hellström L, Reynisdottir S, Lönnqvist F, Eriksson P, Lannfelt L, Amer P: Human beta-2 receptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function. J Clin Invest 100: 3005-13, 1997.
-
(1997)
J Clin Invest
, vol.100
, pp. 3005-3013
-
-
Valerie, L.1
Hellström, L.2
Reynisdottir, S.3
Lönnqvist, F.4
Eriksson, P.5
Lannfelt, L.6
Amer, P.7
-
350
-
-
0031963964
-
Defects in insulin secretion and insulin action in non-insulin dependent diabetes mellitus are inherited
-
Vaukhonen I, Niskanen L, Vanninen E, Uusitupa M, Laakso M: Defects in insulin secretion and insulin action in non-insulin dependent diabetes mellitus are inherited. J Clin Invest 101: 86-96, 1997.
-
(1997)
J Clin Invest
, vol.101
, pp. 86-96
-
-
Vaukhonen, I.1
Niskanen, L.2
Vanninen, E.3
Uusitupa, M.4
Laakso, M.5
-
351
-
-
0033842777
-
Maternel diabetes alters birth weight in glucokinase-deficient (MODY2) kindred but has no influence on adult weight, height, insulin secretion or insulin sensitivity
-
Velho G, Hattersley AT, froguel P: Maternel diabetes alters birth weight in glucokinase-deficient (MODY2) kindred but has no influence on adult weight, height, insulin secretion or insulin sensitivity. Diabetologia 43: 1060-63, 2000.
-
(2000)
Diabetologia
, vol.43
, pp. 1060-1063
-
-
Velho, G.1
Hattersley, A.T.2
Froguel, P.3
-
352
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ et al: The sequence of the human genome. Science 291: 1304-1351, 2001.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
-
353
-
-
0026315717
-
Impaired expression of glycogen synthase mRNA in skeletal muscle of NIDDM patients
-
Vestergaard H, Bjørbæk C, Andersen PH, Bak JF, Pedersen O: Impaired expression of glycogen synthase mRNA in skeletal muscle of NIDDM patients. Diabetes 40: 1740-1745, 1991.
-
(1991)
Diabetes
, vol.40
, pp. 1740-1745
-
-
Vestergaard, H.1
Bjørbæk, C.2
Andersen, P.H.3
Bak, J.F.4
Pedersen, O.5
-
354
-
-
0028842531
-
Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients
-
Vestergaard H, Bjorbaek C, Hansen T, Larsen FS, Granner DK, Pedersen O: Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients. J Clin Invest 96: 2639-45, 1995.
-
(1995)
J Clin Invest
, vol.96
, pp. 2639-2645
-
-
Vestergaard, H.1
Bjorbaek, C.2
Hansen, T.3
Larsen, F.S.4
Granner, D.K.5
Pedersen, O.6
-
355
-
-
0032993608
-
Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism
-
Vestergaard H: Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism. Dan Med Bull 46: 13-34, 1999.
-
(1999)
Dan Med Bull
, vol.46
, pp. 13-34
-
-
Vestergaard, H.1
-
356
-
-
0028902091
-
Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142→His substitution
-
Vidal-Pluig A, Printz RL, Stratton IM, Granner DK, Moller DE: Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142→His substitution. Diabetes 44: 340-346, 1995.
-
(1995)
Diabetes
, vol.44
, pp. 340-346
-
-
Vidal-Pluig, A.1
Printz, R.L.2
Stratton, I.M.3
Granner, D.K.4
Moller, D.E.5
-
357
-
-
0042570843
-
Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
-
Virkamaki A, Ueki K, Kahn CR: Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Invest 103: 931-43, 1999.
-
(1999)
J Clin Invest
, vol.103
, pp. 931-943
-
-
Virkamaki, A.1
Ueki, K.2
Kahn, C.R.3
-
358
-
-
0034104298
-
The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes
-
Waeber G, Delplanque J, bonny C, Steinmann M, Widmann C, Maillard A, Miklossy J, Dina C, Hani EH, Vionnet N, Nicod P, Boutin P, Froguel P: The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes. Nat Genet 24: 291-295, 2000.
-
(2000)
Nat Genet
, vol.24
, pp. 291-295
-
-
Waeber, G.1
Delplanque, J.2
Bonny, C.3
Steinmann, M.4
Widmann, C.5
Maillard, A.6
Miklossy, J.7
Dina, C.8
Hani, E.H.9
Vionnet, N.10
Nicod, P.11
Boutin, P.12
Froguel, P.13
-
359
-
-
0032980306
-
Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus
-
Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators
-
Watanabe RM, Valle T, Hauser ER, Ghosh S, Eriksson J, Kohtamaki K, Ehnholm C, Tuomilehto J, Collins FS, Bergman RN, Boehnke M: Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators. Hum Hered 49: 159-68, 1999.
-
(1999)
Hum Hered
, vol.49
, pp. 159-168
-
-
Watanabe, R.M.1
Valle, T.2
Hauser, E.R.3
Ghosh, S.4
Eriksson, J.5
Kohtamaki, K.6
Ehnholm, C.7
Tuomilehto, J.8
Collins, F.S.9
Bergman, R.N.10
Boehnke, M.11
-
360
-
-
0033564275
-
Genetic dissection of "OLETF", a rat model for non-insulin dependent diabetes mellitus: Quantitative trait locus analysis of (OLETF × BN) × OLETF
-
Watanabe TK, Okuno S, Mizoguchi-Miyagita A, Tsuji A, Yamasaki Y, Hishigaki H, Kanemoto N, Takagaki T, Takahashi E, Irie Y, Nakamura Y, Tanigami A: Genetic dissection of "OLETF", a rat model for non-insulin dependent diabetes mellitus: quantitative trait locus analysis of (OLETF × BN) × OLETF. Genomics 58: 233-9, 1999.
-
(1999)
Genomics
, vol.58
, pp. 233-239
-
-
Watanabe, T.K.1
Okuno, S.2
Mizoguchi-Miyagita, A.3
Tsuji, A.4
Yamasaki, Y.5
Hishigaki, H.6
Kanemoto, N.7
Takagaki, T.8
Takahashi, E.9
Irie, Y.10
Nakamura, Y.11
Tanigami, A.12
-
361
-
-
0027457357
-
Abnormal activation of glycogen synthesis in fibroblasts from NIDDM subjects: Evidence for an abnormality specific to glucose metabolism
-
Wells AM, Sutcliffe IC, Johnson AB, Taylor R: Abnormal activation of glycogen synthesis in fibroblasts from NIDDM subjects: Evidence for an abnormality specific to glucose metabolism. Diabetes 42: 583-589, 1993.
-
(1993)
Diabetes
, vol.42
, pp. 583-589
-
-
Wells, A.M.1
Sutcliffe, I.C.2
Johnson, A.B.3
Taylor, R.4
-
362
-
-
0035137251
-
Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations
-
Weng J, Macfarlane WM, Lehto M, Gu HF, Shepherd LM, Ivarsson SA, Wibell L, Smith T, Groop LC: Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations. Diabetologia 44: 249-258, 2001.
-
(2001)
Diabetologia
, vol.44
, pp. 249-258
-
-
Weng, J.1
Macfarlane, W.M.2
Lehto, M.3
Gu, H.F.4
Shepherd, L.M.5
Ivarsson, S.A.6
Wibell, L.7
Smith, T.8
Groop, L.C.9
-
364
-
-
0028978913
-
Association of a polymorphism in the β3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns
-
Widen E, Lehto M, Kanninen T, Walstron J, Shuldiner AR, Groop LC: Association of a polymorphism in the β3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. N Engl J Med 333: 348-51, 1995.
-
(1995)
N Engl J Med
, vol.333
, pp. 348-351
-
-
Widen, E.1
Lehto, M.2
Kanninen, T.3
Walstron, J.4
Shuldiner, A.R.5
Groop, L.C.6
-
365
-
-
0034893106
-
A genomewide scan for loci predisposing to type 2 diabetes in a u.k. population (the diabetes uk warren 2 repository): Analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q
-
Wiltshire S, Hattersley AT, Hitman GA, Walker M, Levy JC, Sampson M, O'Rahilly S, Frayling TM, Bell JI, Lathrop GM, Bennett A, Dhillon R, Fletcher C, Groves CJ, Jones E, Prestwich P, Simecek N, Rao PV, Wishart M, Foxon R, Howell S, Smedley D, Cardon LR, Menzel S, McCarthy MI: A genomewide scan for loci predisposing to type 2 diabetes in a u.k. population (the diabetes uk warren 2 repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet 69: 553-69, 2001.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 553-569
-
-
Wiltshire, S.1
Hattersley, A.T.2
Hitman, G.A.3
Walker, M.4
Levy, J.C.5
Sampson, M.6
O'Rahilly, S.7
Frayling, T.M.8
Bell, J.I.9
Lathrop, G.M.10
Bennett, A.11
Dhillon, R.12
Fletcher, C.13
Groves, C.J.14
Jones, E.15
Prestwich, P.16
Simecek, N.17
Rao, P.V.18
Wishart, M.19
Foxon, R.20
Howell, S.21
Smedley, D.22
Cardon, L.R.23
Menzel, S.24
McCarthy, M.I.25
more..
-
366
-
-
0032567937
-
Disruption of IRS-2 causes type 2 diabetes in mice
-
Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, White MF: Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391: 900-904, 1998.
-
(1998)
Nature
, vol.391
, pp. 900-904
-
-
Withers, D.J.1
Gutierrez, J.S.2
Towery, H.3
Burks, D.J.4
Ren, J.M.5
Previs, S.6
Zhang, Y.7
Bernal, D.8
Pons, S.9
Shulman, G.I.10
Bonner-Weir, S.11
White, M.F.12
-
367
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/Factor A
-
Woodgett JR: Molecular cloning and expression of glycogen synthase kinase-3/Factor A. EMBO J. 9: 8: 2431-2438, 1990.
-
(1990)
EMBO J
, vol.9
, Issue.8
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
368
-
-
0025761472
-
A common denominator linking glycogen metabolism, nuclear oncogenes and development
-
Woodgett JR: A common denominator linking glycogen metabolism, nuclear oncogenes and development. TIBS 16: 177-181, 1991.
-
(1991)
TIBS
, vol.16
, pp. 177-181
-
-
Woodgett, J.R.1
-
369
-
-
0030873949
-
Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene
-
Wu KL, Gannon M, Peshavaria M, Offield MF, Henderson E, Ray M, Marks A, Gamer LW, Wright CV, Stein R: Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene. Mol Cell Biol 17: 6002-13, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6002-6013
-
-
Wu, K.L.1
Gannon, M.2
Peshavaria, M.3
Offield, M.F.4
Henderson, E.5
Ray, M.6
Marks, A.7
Gamer, L.W.8
Wright, C.V.9
Stein, R.10
-
370
-
-
0031688058
-
A common variant in the PPP1R3 associated with insulin resistance and type 2 diabetes
-
Xia J, Scherer SW, Cohen PTW, Majer M, Xi T, Norman RA, Knowler WC, Bogardus C, Prochazka M: A common variant in the PPP1R3 associated with insulin resistance and type 2 diabetes. Diabetes 47: 1519-24, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 1519-1524
-
-
Xia, J.1
Scherer, S.W.2
Cohen, P.T.W.3
Majer, M.4
Xi, T.5
Norman, R.A.6
Knowler, W.C.7
Bogardus, C.8
Prochazka, M.9
-
371
-
-
0030816420
-
Identification of mutations in the hepatocyte nuclear factor (HNF)-1 alpha gene in Japanese subjects with IDDM
-
Yamada S, Nishigori H, Onda H, Utsugi T, Yanagawa T, Maruyama T, Onigata K, Nagashima K, Nagai R, Morikawa A, Takeuchi T, Takeda J: Identification of mutations in the hepatocyte nuclear factor (HNF)-1 alpha gene in Japanese subjects with IDDM. Diabetologia 46: 1643-47, 1997.
-
(1997)
Diabetologia
, vol.46
, pp. 1643-1647
-
-
Yamada, S.1
Nishigori, H.2
Onda, H.3
Utsugi, T.4
Yanagawa, T.5
Maruyama, T.6
Onigata, K.7
Nagashima, K.8
Nagai, R.9
Morikawa, A.10
Takeuchi, T.11
Takeda, J.12
-
372
-
-
0034107606
-
Cloning of cDNA and the gene encoding human hepatocyte nuclear factor (HNF)-3 beta and mutation screening in Japanese subjects with maturity-onset diabetes of the young
-
Yamada S, Zhu Q, Aihira Y, Onda H, Zhang Z, Yu L, Jin L, Si YJ, Nishigori H, Tomura H, Inoue I, Morikawa A, yamagata K, Hanafusa T, Matsuzawa Y, Takeda J: Cloning of cDNA and the gene encoding human hepatocyte nuclear factor (HNF)-3 beta and mutation screening in Japanese subjects with maturity-onset diabetes of the young. Diabetologia 43: 121-4, 2000.
-
(2000)
Diabetologia
, vol.43
, pp. 121-124
-
-
Yamada, S.1
Zhu, Q.2
Aihira, Y.3
Onda, H.4
Zhang, Z.5
Yu, L.6
Jin, L.7
Si, Y.J.8
Nishigori, H.9
Tomura, H.10
Inoue, I.11
Morikawa, A.12
Yamagata, K.13
Hanafusa, T.14
Matsuzawa, Y.15
Takeda, J.16
-
373
-
-
0035433199
-
NeuroD/BETA2 gene g → a polymorphism may affect onset pattern of type 1 diabetes in Japanese
-
Yamada S, Motohashi Y, Yanagawa T, Maruyama T, Kasuga A, Hirose H, Matsubara K, Shimada A, Saruta T: NeuroD/BETA2 gene g → a polymorphism may affect onset pattern of type 1 diabetes in Japanese. Diabetes Care 24: 1438-41, 2001.
-
(2001)
Diabetes Care
, vol.24
, pp. 1438-1441
-
-
Yamada, S.1
Motohashi, Y.2
Yanagawa, T.3
Maruyama, T.4
Kasuga, A.5
Hirose, H.6
Matsubara, K.7
Shimada, A.8
Saruta, T.9
-
374
-
-
10544249874
-
Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)
-
Yamagata K, Oda N, Kaisaki PJ, Menzel S, Furuta H, Vaxillaire M, Southam L, Cox RD, Lathrop GM, Boriraj VV, Chen X, Cox NJ, Oda Y, Yano H, Le Beau MM, Yamada S, Nishigori H, Takeda J, Fajans SS, Hattersley AT, Iwasaki N, Hansen T, Pedersen O, Polonsky KS, Turner RC, Velho G, Chevre JC, Froguel P, Bell GI: Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3). Nature 384: 455-458, 1996a.
-
(1996)
Nature
, vol.384
, pp. 455-458
-
-
Yamagata, K.1
Oda, N.2
Kaisaki, P.J.3
Menzel, S.4
Furuta, H.5
Vaxillaire, M.6
Southam, L.7
Cox, R.D.8
Lathrop, G.M.9
Boriraj, V.V.10
Chen, X.11
Cox, N.J.12
Oda, Y.13
Yano, H.14
Le Beau, M.M.15
Yamada, S.16
Nishigori, H.17
Takeda, J.18
Fajans, S.S.19
Hattersley, A.T.20
Iwasaki, N.21
Hansen, T.22
Pedersen, O.23
Polonsky, K.S.24
Turner, R.C.25
Velho, G.26
Chevre, J.C.27
Froguel, P.28
Bell, G.I.29
more..
-
375
-
-
10544236911
-
Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1)
-
Yamagata K, Furuta H, Oda N, Kaisaki PJ, Menzel S, Cox NJ, Fajans SS, Signorini S, Stoffel M, Bell GI: Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1). Nature 384: 458-459, 1996b.
-
(1996)
Nature
, vol.384
, pp. 458-459
-
-
Yamagata, K.1
Furuta, H.2
Oda, N.3
Kaisaki, P.J.4
Menzel, S.5
Cox, N.J.6
Fajans, S.S.7
Signorini, S.8
Stoffel, M.9
Bell, G.I.10
-
376
-
-
2142856418
-
Diabetes and pancreatic tumors in transgenic mice expressing Pax6
-
Yamaoka T, Yano M, Yamada Matsushita T, Moritani M, Ii S, yoshimoto K, Hata J, Itakura M: Diabetes and pancreatic tumors in transgenic mice expressing Pax6. Diabetologia 43: 332-9, 2000.
-
(2000)
Diabetologia
, vol.43
, pp. 332-339
-
-
Yamaoka, T.1
Yano, M.2
Yamada Matsushita, T.3
Moritani, M.4
Ii, S.5
Yoshimoto, K.6
Hata, J.7
Itakura, M.8
-
377
-
-
0023886838
-
Insulin-resistant diabetes due to a point mutation that prevents insulin proreceptor processing
-
Yoshimasa Y, Seino S, Whittaker J, Kakehi T, Kosaki A, Kuzuya H, Imura H, Bell GI, Steiner DF: Insulin-resistant diabetes due to a point mutation that prevents insulin proreceptor processing. Science 240: 784-787, 1988.
-
(1988)
Science
, vol.240
, pp. 784-787
-
-
Yoshimasa, Y.1
Seino, S.2
Whittaker, J.3
Kakehi, T.4
Kosaki, A.5
Kuzuya, H.6
Imura, H.7
Bell, G.I.8
Steiner, D.F.9
-
378
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta-cell dysfunction and type 2 diabetes
-
Zhang C-Y, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, Vidal-Puig AV, Boss O, Kim Y-B, Zheng XX, Wheeler MB, Shulman GI, Lowell BB: Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta-cell dysfunction and type 2 diabetes. Cell 105: 745-755, 2001.
-
(2001)
Cell
, vol.105
, pp. 745-755
-
-
Zhang, C.-Y.1
Baffy, G.2
Perret, P.3
Krauss, S.4
Peroni, O.5
Grujic, D.6
Hagen, T.7
Vidal-Puig, A.V.8
Boss, O.9
Kim, Y.-B.10
Zheng, X.X.11
Wheeler, M.B.12
Shulman, G.I.13
Lowell, B.B.14
-
379
-
-
0029857775
-
UKPDS19: Heterogeneity in NIDDM: Separate contributions of IRS-1 and Beta 3-adrenergic receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations. UK Prospective Diabetes Study
-
Zhang Y, Wat N, Stratton IM, Warren-Perry MG, Orho M, Groop L, Turner RC:UKPDS19: heterogeneity in NIDDM: separate contributions of IRS-1 and Beta 3-adrenergic receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations. UK Prospective Diabetes Study. Diabetologia 39: 1505-11, 1996.
-
(1996)
Diabetologia
, vol.39
, pp. 1505-1511
-
-
Zhang, Y.1
Wat, N.2
Stratton, I.M.3
Warren-Perry, M.G.4
Orho, M.5
Groop, L.6
Turner, R.C.7
-
380
-
-
0030896748
-
The global epidemiology of noninsulin-dependent diabetes mellitus and the metabolic syndrome
-
Zimmet PZ, McCarty DJ, de Courten MP: The global epidemiology of noninsulin-dependent diabetes mellitus and the metabolic syndrome. J Diabetes Complications 11: 60-68, 1997.
-
(1997)
J Diabetes Complications
, vol.11
, pp. 60-68
-
-
Zimmet, P.Z.1
McCarty, D.J.2
De Courten, M.P.3
-
381
-
-
0027215282
-
Polymorphism of the glycogen synthase gene and non-insulin dependent-diabetes mellitus
-
Zouali H, Velho G, Froguel P: Polymorphism of the glycogen synthase gene and non-insulin dependent-diabetes mellitus. N Engl J Med 328: 1568-69, 1993.
-
(1993)
N Engl J Med
, vol.328
, pp. 1568-1569
-
-
Zouali, H.1
Velho, G.2
Froguel, P.3
-
382
-
-
0030766446
-
A susceptibility locus for early-onset non-insulin dependent diabetes (type 2) mellitus maps to chromosome 20q, proximal to the phosphoenolpyrovate carboxylase gene
-
Zouali H, Hani EH, Philippi A, Vionnet N, Beckmann JS, Demenais F, Froguel: A susceptibility locus for early-onset non-insulin dependent diabetes (type 2) mellitus maps to chromosome 20q, proximal to the phosphoenolpyrovate carboxylase gene: J. Hum. Mol. Genet. 6: 1401-1408, 1997.
-
(1997)
J Hum Mol Genet
, vol.6
, pp. 1401-1408
-
-
Zouali, H.1
Hani, E.H.2
Philippi, A.3
Vionnet, N.4
Beckmann, J.S.5
Demenais, F.6
Froguel7
-
383
-
-
0343602237
-
Promiscous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels
-
Ämmäla C, Moorhouse A, Gribble F, Ashfield R, Proks P, Smith PA, Sakura H, Coles B, Ashcroft SJH, Ashcroft FM: Promiscous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels. Nature 379: 545-548. 1996.
-
(1996)
Nature
, vol.379
, pp. 545-548
-
-
Ämmäla, C.1
Moorhouse, A.2
Gribble, F.3
Ashfield, R.4
Proks, P.5
Smith, P.A.6
Sakura, H.7
Coles, B.8
Ashcroft, S.J.H.9
Ashcroft, F.M.10
|