Role of mitochondrial DNA tRNA leucine and glucagon receptor missense mutations in Utah white diabetic patients

Diabetes Care

Volumn 19, Issue 5, 1996, Pages 507-508

  Elbein, Steven C ^a,b   Hoffman, Michael D ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON RECEPTOR; TRANSFER RNA;

ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DNA SEQUENCE; ETHNOLOGY; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; RECEPTOR GENE; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 0029976297     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.19.5.507     Document Type: Article

References (10)

1. Elbein SC, Hoffman MD, Mayorga RA, Bragg KL The genetics of NIDDM: an update Diabetes Care 17:1523-1533, 1994
2. Reardon W, Ross RJM, Sweeney MG, Luxon LM, Pembrey ME, Harding AE, Trembath RC: Diabetes associated with a pathogenic point mutation in mitochondrial DNA. Lancet 340:1376-1379, 1992
3. Leu(UUR) in a large pedigree with maternally transmitted type II diabetes and deafness. Nat Genet 1:368-371, 1992
4. Hager J, Hansen L, Vaisse C, Vionnet N, Philippi A, Poller W, Velho G, Carcassi C, Contu L, Julier C, Cambien F, Passa P, Lathrop M, Kindsvogel W, Demenais F, Nishimura E, Froguel P: A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus. Nat Genet 9:299-304, 1995
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6. Vionnet N, Passa P, Froguel P: Prevalence of mitochondrial gene mutations in families with diabetes mellitus. Lancet 342: 1429-1430, 1993
7. Froguel PH, Zouali H, Vionnet N, Velho G, Vaxillaire M, Sun F, Lesage S, Stoffel M, Takeda J, Passa PH, Permutt MA, Beckmann JS, Bell GI, Cohen D. Familial hyperglycemia due to mutations in glucokinase: definition of a subtype of diabetes mellitus. N Engl J Med 328:697-702, 1993
8. Elbein SC, Hoffman M, Chiu K, Tanizawa Y, Permutt MA: Linkage analysis of the glucokinase locus in familial type 2 (non-insulin dependent) diabetic pedigrees. Diabetologia 36:141-145, 1993
9. Elbein SC, Hoffman M, Qin H, Chiu K, Tanizawa Y, Permutt MA. Molecular screening of the glucokinase gene in familial type 2 (non-insulin-dependent) diabetes mellitus Diabetologia 37:182-187, 1994
10. McLellan T, Jorde LB, Skolnick MH: Genetic distances between Utah Mormons and related populations. Am J Hum Genet 36:836-857, 1984