Association of the insulin-receptor variant Met-985 with hyperglycemia and non-insulin-dependent diabetes mellitus in the Netherlands: A population- based study

American Journal of Human Genetics

Volumn 59, Issue 5, 1996, Pages 1119-1125

  'T Hart, L M ^a   Stolk, R P ^b   Heine, R J ^b   Grobbee, D E ^b   Van Der Does, F E E ^b   Maassen, J A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Sylvius Laboratory ^*

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR; METHIONINE;

ARTICLE; DISEASE ASSOCIATION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN RESISTANCE; NETHERLANDS; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; POPULATION RESEARCH; PRIORITY JOURNAL; RECEPTOR GENE;

BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; INSULIN RESISTANCE; METHIONINE; NETHERLANDS; POINT MUTATION; RECEPTOR, INSULIN; RISK;

EID: 0029907562     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

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2. Eck MJ, Dhe-Paganon S, Trüb T, Nolte RT, Shoelson SE (1996) Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor. Cell 85:695-705
3. Elbein SC, Sorensen LK, Schumacher MC (1993) Methionine for valine substitution in exon 17 of the insulin receptor gene in a pedigree with familial NIDDM. Diabetes 42:429-434
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5. Feskens EJM, Loeber JG, Kromhout D (1994) Diet and physical activity as determinants of hyperinsulinemia: the Zutphen elderly study. Am J Epidemiol 140:350-360