Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes

Nature Genetics

Volumn 26, Issue 3, 2000, Pages 336-340

  Silva, José P ^a   Köhler, Martin ^a   Graff, Caroline ^a   Oldfors, Anders ^b   Magnuson, Mark A ^c   Berggren, Per Olof ^a   Larsson, Nils Göran ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; DIABETES MELLITUS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; AGE FACTORS; ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; ELECTRON TRANSPORT COMPLEX IV; EXOCYTOSIS; GENE TARGETING; GLUCOSE; HIGH MOBILITY GROUP PROTEINS; HUMANS; INSULIN; INTEGRASES; ION TRANSPORT; ISLETS OF LANGERHANS; MICE; MICE, TRANSGENIC; MITOCHONDRIAL PROTEINS; NUCLEAR PROTEINS; ORGAN SPECIFICITY; OXIDATIVE PHOSPHORYLATION; POTASSIUM CHANNELS; RECOMBINANT FUSION PROTEINS; SECRETORY RATE; SUCCINATE DEHYDROGENASE; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSGENES; VIRAL PROTEINS; XENOPUS PROTEINS;

ANIMALIA;

EID: 0033762782     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/81649     Document Type: Article

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