Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes

Cell

Volumn 105, Issue 6, 2001, Pages 745-755

  Zhang, Chen Yu ^a   Baffy, György ^a,b   Perret, Pascale ^c   Krauss, Stefan ^a   Peroni, Odile ^a   Grujic, Danica ^a   Hagen, Thilo ^a   Vidal Puig, Antonio J ^a   Boss, Olivier ^a   Kim, Young Bum ^a   Zheng, Xin Xiao ^a   Wheeler, Michael B ^d   Shulman, Gerald I ^c   Chan, Catherine B ^e   Lowell, Bradford B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; INSULIN; MESSENGER RNA; PROTON; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; COLD EXPOSURE; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE TARGETING; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN BLOOD LEVEL; INSULIN RELEASE; KNOCKOUT MOUSE; MALE; MITOCHONDRION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; THERMOGENESIS; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0035875087     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00378-6     Document Type: Article

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