-
1
-
-
0029950724
-
The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
-
Ahlgren, U., J. Jonsson, and H. Edlund. 1996. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122:1409-1416.
-
(1996)
Development
, vol.122
, pp. 1409-1416
-
-
Ahlgren, U.1
Jonsson, J.2
Edlund, H.3
-
2
-
-
0031020002
-
Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells
-
Ahlgren, U., S. L. Pfaff, T. M. Jessell, T. Edlund, and H. Edlund. 1997. Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Nature 385:257-260.
-
(1997)
Nature
, vol.385
, pp. 257-260
-
-
Ahlgren, U.1
Pfaff, S.L.2
Jessell, T.M.3
Edlund, T.4
Edlund, H.5
-
3
-
-
0025572707
-
Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection
-
Blackwell, T. K., and H. Weintraub. 1990. Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection. Science 250:1104-1110.
-
(1990)
Science
, vol.250
, pp. 1104-1110
-
-
Blackwell, T.K.1
Weintraub, H.2
-
4
-
-
0027426925
-
DNA sequence recognition by Pax proteins: Bipartite structure of the paired domain and its binding site
-
Czerny, T., G. Schaffner, and M. Busslinger. 1993. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7:2048-2061.
-
(1993)
Genes Dev.
, vol.7
, pp. 2048-2061
-
-
Czerny, T.1
Schaffner, G.2
Busslinger, M.3
-
5
-
-
0029874066
-
C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8
-
Dorfler, P., and M. Busslinger. 1996. C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8. EMBO J. 15:1971-1982.
-
(1996)
EMBO J.
, vol.15
, pp. 1971-1982
-
-
Dorfler, P.1
Busslinger, M.2
-
6
-
-
0031840442
-
Dual roles for Pax-6: A transcriptional repressor of lens fiber cell-specific β-crystallin genes
-
Duncan, M. K., J. I. Haynes II, A. Cvekl, and J. Piatigorsky. 1998. Dual roles for Pax-6: a transcriptional repressor of lens fiber cell-specific β-crystallin genes. Mol. Cell. Biol. 18:5579-5586.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5579-5586
-
-
Duncan, M.K.1
Haynes J.I. II2
Cvekl, A.3
Piatigorsky, J.4
-
7
-
-
0028239775
-
Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes
-
Epstein, J., J. Cai, T. Glaser, L. Jepeal, and R. Maas. 1994. Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes, J. Biol. Chem. 269:8355-8361.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8355-8361
-
-
Epstein, J.1
Cai, J.2
Glaser, T.3
Jepeal, L.4
Maas, R.5
-
8
-
-
0028096639
-
Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing
-
Epstein, J. A., T. Glaser, J. Cai, L. Jepeal, D. S. Walton, and R. L. Maas. 1994. Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes Dev. 8:2022-2034.
-
(1994)
Genes Dev.
, vol.8
, pp. 2022-2034
-
-
Epstein, J.A.1
Glaser, T.2
Cai, J.3
Jepeal, L.4
Walton, D.S.5
Maas, R.L.6
-
9
-
-
0029817071
-
Drosophila paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain
-
Fujioka, M., P. Miskiewicz, L. Raj, A. A. Gulledge, M. Weir, and T. Goto. 1996. Drosophila Paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain. Development 122:2697-2707.
-
(1996)
Development
, vol.122
, pp. 2697-2707
-
-
Fujioka, M.1
Miskiewicz, P.2
Raj, L.3
Gulledge, A.A.4
Weir, M.5
Goto, T.6
-
10
-
-
0033508033
-
Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: A possible role of Pax4 as a transcriptional repressor in the pancreas
-
Fujitani, Y., Y. Kajimoto, T. Yasada, T. Matsuoka, H. Kaneto, Y. Umayahara, N. Fujita, H. Watada, J. Miyazaki, Y. Yamasaki, and M. Hori. 1999. Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a possible role of Pax4 as a transcriptional repressor in the pancreas. Mol. Cell. Biol. 19:8281-8291.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8281-8291
-
-
Fujitani, Y.1
Kajimoto, Y.2
Yasada, T.3
Matsuoka, T.4
Kaneto, H.5
Umayahara, Y.6
Fujita, N.7
Watada, H.8
Miyazaki, J.9
Yamasaki, Y.10
Hori, M.11
-
11
-
-
0029095353
-
The insulin gene promoter
-
German, M., S. Ashcroft, K. Docherty, H. Edlund, T. Edlund, S. Goodison, H. Imura, G. Kennedy, O. Madsen, D. Melloul, L. Moss, K. Olson, M. A. Permutt, J. Philippe, R. P. Robertson, W. J. Rutter, P. Serup, R. Stein, D. Steiner, M.-J. Tsai, and M. D. Walker. 1995. The insulin gene promoter. Diabetes 44:1002-1004.
-
(1995)
Diabetes
, vol.44
, pp. 1002-1004
-
-
German, M.1
Ashcroft, S.2
Docherty, K.3
Edlund, H.4
Edlund, T.5
Goodison, S.6
Imura, H.7
Kennedy, G.8
Madsen, O.9
Melloul, D.10
Moss, L.11
Olson, K.12
Permutt, M.A.13
Philippe, J.14
Robertson, R.P.15
Rutter, W.J.16
Serup, P.17
Stein, R.18
Steiner, D.19
Tsai, M.-J.20
Walker, M.D.21
more..
-
12
-
-
0002466710
-
Insulin gene structure and regulation
-
B. Draznin and D. LeRoith (ed.), Humana Press Inc., Totawa, N.J.
-
German, M. S. 1994. Insulin gene structure and regulation, p. 91-117. In B. Draznin and D. LeRoith (ed.), Molecular biology of diabetes, part 1. Humana Press Inc., Totawa, N.J.
-
(1994)
Molecular Biology of Diabetes, Part 1
, pp. 91-117
-
-
German, M.S.1
-
13
-
-
0026602931
-
The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical β-cell nuclear complexes
-
German, M. S., L. G. Moss, J. Wang, and W. J. Rutter. 1992. The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical β-cell nuclear complexes. Mol. Cell. Biol. 12:1777-1788.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 1777-1788
-
-
German, M.S.1
Moss, L.G.2
Wang, J.3
Rutter, W.J.4
-
14
-
-
0026471057
-
Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: Building a functional insulin minienhancer complex
-
German, M. S., J. Wang, R. B. Chadwick, and W. J. Rutter. 1992. Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex. Genes Dev. 6:2165-2176.
-
(1992)
Genes Dev.
, vol.6
, pp. 2165-2176
-
-
German, M.S.1
Wang, J.2
Chadwick, R.B.3
Rutter, W.J.4
-
15
-
-
0030041280
-
Lineage-specific morphogenesis in the developing pancreas: Role of mesenchymal factors
-
Gittes, G. K., P. E. Galante, D. Hanahan, W. J. Rutter, and H. T. Debas. 1996. Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors. Development 122:439-447.
-
(1996)
Development
, vol.122
, pp. 439-447
-
-
Gittes, G.K.1
Galante, P.E.2
Hanahan, D.3
Rutter, W.J.4
Debas, H.T.5
-
16
-
-
0026518591
-
Onset of cell-specific gene expression in the developing mouse pancreas
-
Gittes, G. K., and W. J. Rutter. 1992. Onset of cell-specific gene expression in the developing mouse pancreas. Proc. Natl. Acad. Sci. USA 89:1128-1132.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 1128-1132
-
-
Gittes, G.K.1
Rutter, W.J.2
-
17
-
-
0028074973
-
PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects
-
Glaser, T., L. Jepeal, J. G. Edwards, S. R. Young, J. Favor, and R. L. Maas. 1994. PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects. Nat Genet. 7:463-471.
-
(1994)
Nat Genet.
, vol.7
, pp. 463-471
-
-
Glaser, T.1
Jepeal, L.2
Edwards, J.G.3
Young, S.R.4
Favor, J.5
Maas, R.L.6
-
18
-
-
0032512538
-
Isolation of full-length cDNA of mouse PAX4 gene and identification of its human homologue
-
Inoue, H., J. Nomiyama, K. Nakai, A. Matsutani, Y. Tanizawa, and Y. Oka. 1998. Isolation of full-length cDNA of mouse PAX4 gene and identification of its human homologue. Biochem. Biophys. Res. Commun. 243:628-633.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.243
, pp. 628-633
-
-
Inoue, H.1
Nomiyama, J.2
Nakai, K.3
Matsutani, A.4
Tanizawa, Y.5
Oka, Y.6
-
19
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson, J., L. Carlsson, T. Edlund, and H. Edlund. 1994. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371:606-609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
20
-
-
0029837282
-
Cooperative interactions between paired domain and homeodomain
-
Jun, S., and C. Desplan. 1996. Cooperative interactions between paired domain and homeodomain. Development 122:2639-2650.
-
(1996)
Development
, vol.122
, pp. 2639-2650
-
-
Jun, S.1
Desplan, C.2
-
21
-
-
0025935925
-
The pancreatic islet-specific glucagon G3 transcription factors recognize control elements in the rat somatostatin and insulin-I genes
-
Knepel, W., M. Vallejo, J. A. Chafitz, and J. F. Habener. 1991. The pancreatic islet-specific glucagon G3 transcription factors recognize control elements in the rat somatostatin and insulin-I genes. Mol. Endocrinol. 5:1457-1466.
-
(1991)
Mol. Endocrinol.
, vol.5
, pp. 1457-1466
-
-
Knepel, W.1
Vallejo, M.2
Chafitz, J.A.3
Habener, J.F.4
-
22
-
-
0032580207
-
Allosteric effects of DNA on transcriptional regulators
-
Lefstin, J. A., and K. R. Yamamoto. 1998. Allosteric effects of DNA on transcriptional regulators. Nature 392:885-888.
-
(1998)
Nature
, vol.392
, pp. 885-888
-
-
Lefstin, J.A.1
Yamamoto, K.R.2
-
23
-
-
0031937851
-
Drosophila goosecoid requires a conserved heptapeptide for repression of paired-class homeoprotein activators
-
Mailhos, C., S. Andre, B. Mollereau, A. Goriely, A. Hemmati-Brivanlou, and C. Desplan. 1998. Drosophila Goosecoid requires a conserved heptapeptide for repression of paired-class homeoprotein activators. Development 125: 937-947.
-
(1998)
Development
, vol.125
, pp. 937-947
-
-
Mailhos, C.1
Andre, S.2
Mollereau, B.3
Goriely, A.4
Hemmati-Brivanlou, A.5
Desplan, C.6
-
24
-
-
0030886674
-
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice
-
Naya, F. J., H. P. Huang, Y. Qiu, H. Mutoh, F. J. DeMayo, A. B. Leiter, and M. J. Tsai. 1997. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev. 11:2323-2334.
-
(1997)
Genes Dev.
, vol.11
, pp. 2323-2334
-
-
Naya, F.J.1
Huang, H.P.2
Qiu, Y.3
Mutoh, H.4
DeMayo, F.J.5
Leiter, A.B.6
Tsai, M.J.7
-
25
-
-
0030070145
-
Function of the human insulin promoter in primary cultured islet cells
-
Odagiri, H., J. Wang, and M. S. German. 1996. Function of the human insulin promoter in primary cultured islet cells. J. Biol. Chem. 271:1909-1915.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1909-1915
-
-
Odagiri, H.1
Wang, J.2
German, M.S.3
-
26
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
Offield, M. F., T. L. Jetton, P. A. Labosky, M. Ray, R. W. Stein, M. A. Magnuson, B. L. M. Hogan, and C. V. E. Wright. 1996. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 122:983-995.
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
Ray, M.4
Stein, R.W.5
Magnuson, M.A.6
Hogan, B.L.M.7
Wright, C.V.E.8
-
27
-
-
0032055491
-
Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes
-
Ogbourne, S., and T. M. Antalis. 1998. Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes. Biochem. J. 331:1-14.
-
(1998)
Biochem. J.
, vol.331
, pp. 1-14
-
-
Ogbourne, S.1
Antalis, T.M.2
-
28
-
-
0032563198
-
Identification of a new binding motif for the paired domain of Pax-3 and unusual characteristics of spacing of bipartite recognition elements on binding and transcription activation
-
Phelan, S. A., and M. R. Loeken. 1998. Identification of a new binding motif for the paired domain of Pax-3 and unusual characteristics of spacing of bipartite recognition elements on binding and transcription activation. J. Biol. Chem. 273:19153-19159.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19153-19159
-
-
Phelan, S.A.1
Loeken, M.R.2
-
29
-
-
0028873948
-
Islet-specific proteins interact with the insulin-response element of the glucagon gene
-
Philippe, J, C. Morel, and M. Cordier-Bussat. 1995. Islet-specific proteins interact with the insulin-response element of the glucagon gene. J. Biol. Chem. 270:3039-3045.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3039-3045
-
-
Philippe, J.1
Morel, C.2
Cordier-Bussat, M.3
-
30
-
-
0032486385
-
Activation and repression of transcription by differential contact: Two sides of a coin
-
Roy, S., S. Garges, and S. Adhya. 1998. Activation and repression of transcription by differential contact: two sides of a coin. J. Biol. Chem. 273: 14059-14062.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14059-14062
-
-
Roy, S.1
Garges, S.2
Adhya, S.3
-
31
-
-
0032578540
-
A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets
-
Sander, M., S. C. Griffen, J. Huang, and M. S. German. 1998. A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets. Proc. Natl. Acad. Sci. USA 95:11572-11577.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11572-11577
-
-
Sander, M.1
Griffen, S.C.2
Huang, J.3
German, M.S.4
-
32
-
-
1842330860
-
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development
-
Sander, M., A. Neubuser, J. Kalamaras, H. C. Ee, G. R. Martin, and M. S. German. 1997. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes Dev. 11:1662-1673.
-
(1997)
Genes Dev.
, vol.11
, pp. 1662-1673
-
-
Sander, M.1
Neubuser, A.2
Kalamaras, J.3
Ee, H.C.4
Martin, G.R.5
German, M.S.6
-
33
-
-
0026687778
-
Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells
-
Shelton, K. D., A. J. Franklin, A. Khoor, J. Beechem, and M. A. Magnuson. 1992. Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells. Mol. Cell. Biol. 12:4578-4589.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 4578-4589
-
-
Shelton, K.D.1
Franklin, A.J.2
Khoor, A.3
Beechem, J.4
Magnuson, M.A.5
-
34
-
-
0029027780
-
Developmental biology of the pancreas
-
Slack, J. M. W. 1995. Developmental biology of the pancreas. Development 121:1569-1580.
-
(1995)
Development
, vol.121
, pp. 1569-1580
-
-
Slack, J.M.W.1
-
35
-
-
0030897629
-
The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas
-
Sosa-Pineda, B., K. Chowdhury, M. Torres, G. Oliver, and P. Grass. 1997. The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas. Nature 384:399-402.
-
(1997)
Nature
, vol.384
, pp. 399-402
-
-
Sosa-Pineda, B.1
Chowdhury, K.2
Torres, M.3
Oliver, G.4
Grass, P.5
-
36
-
-
0030914931
-
Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas
-
St-Onge, L., B. Sosa-Pineda, K. Chowdhury, A. Mansouri, and P. Gruss. 1997. Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas. Nature 387:406-409.
-
(1997)
Nature
, vol.387
, pp. 406-409
-
-
St-Onge, L.1
Sosa-Pineda, B.2
Chowdhury, K.3
Mansouri, A.4
Gruss, P.5
-
37
-
-
0031843386
-
Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
-
Sussel, L., J. Kalamaras, O. C. D. J. Hartigan, J. J. Meneses, R. A. Pedersen, J. L. Rubenstein, and M. S. German. 1998. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125:2213-2221.
-
(1998)
Development
, vol.125
, pp. 2213-2221
-
-
Sussel, L.1
Kalamaras, J.2
Hartigan, O.C.D.J.3
Meneses, J.J.4
Pedersen, R.A.5
Rubenstein, J.L.6
German, M.S.7
-
38
-
-
0000744672
-
Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6
-
Tang, H. K., S. Singh, and G. F. Saunders. 1998. Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6. J. Biol. Chem. 273:7210-7221.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7210-7221
-
-
Tang, H.K.1
Singh, S.2
Saunders, G.F.3
-
39
-
-
0026824439
-
The homeodomain: A new face for the helix-turn-helix?
-
Treisman, J., E. Harris, D. Wilson, and C. Desplan. 1992. The homeodomain: a new face for the helix-turn-helix? Bioessays 14:145-150.
-
(1992)
Bioessays
, vol.14
, pp. 145-150
-
-
Treisman, J.1
Harris, E.2
Wilson, D.3
Desplan, C.4
-
40
-
-
1842369128
-
The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein
-
Underhill, D. A., and P. Gros. 1997. The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein. J. Biol. Chem. 272:14175-14182.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14175-14182
-
-
Underhill, D.A.1
Gros, P.2
-
41
-
-
0032549828
-
Dependence of BSAP repressor and activator functions on BSAP concentration
-
Wallin, J. J., E. R. Gacksletter, and M. E. Koshland. 1998. Dependence of BSAP repressor and activator functions on BSAP concentration. Science 279:1961-1964.
-
(1998)
Science
, vol.279
, pp. 1961-1964
-
-
Wallin, J.J.1
Gacksletter, E.R.2
Koshland, M.E.3
-
42
-
-
0025954965
-
Pax: A multigene family of paired box-containing genes
-
Walther, C., J.-L. Guenet, D. Simon, U. Deutsch, B. Jostes, M. D. Goulding, D. Plachov, R. Balling, and P. Gruss. 1991. Pax: a multigene family of paired box-containing genes. Genomics 11:424-434.
-
(1991)
Genomics
, vol.11
, pp. 424-434
-
-
Walther, C.1
Guenet, J.-L.2
Simon, D.3
Deutsch, U.4
Jostes, B.5
Goulding, M.D.6
Plachov, D.7
Balling, R.8
Gruss, P.9
-
43
-
-
0027332476
-
Cooperative dimerization of paired class homeo domains on DNA
-
Wilson, D., G. Sheng, T. Lecuit, N. Dostatni, and C. Desplan. 1993. Cooperative dimerization of paired class homeo domains on DNA. Genes Dev. 7:2120-2134.
-
(1993)
Genes Dev.
, vol.7
, pp. 2120-2134
-
-
Wilson, D.1
Sheng, G.2
Lecuit, T.3
Dostatni, N.4
Desplan, C.5
-
44
-
-
0028919759
-
Crystal structure of a paired domain-DNA complex at 2.5 Å resolution reveals structural basis for Pax developmental mutations
-
Xu, W., M. A. Rould, S. Jun, C. Desplan, and C. O. Pabo. 1995. Crystal structure of a paired domain-DNA complex at 2.5 Å resolution reveals structural basis for Pax developmental mutations. Cell 80:639-650.
-
(1995)
Cell
, vol.80
, pp. 639-650
-
-
Xu, W.1
Rould, M.A.2
Jun, S.3
Desplan, C.4
Pabo, C.O.5
|