-
1
-
-
0027242129
-
The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential
-
Ahmed, N.N., Franke, T.F., Bellacosa, A., Datta, K., Gonzalez-Portal, M.E., Taguchi, T., Testa, J.R., and Tsichlis, P.N. (1993). The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential. Oncogene 8, 1957-1963.
-
(1993)
Oncogene
, vol.8
, pp. 1957-1963
-
-
Ahmed, N.N.1
Franke, T.F.2
Bellacosa, A.3
Datta, K.4
Gonzalez-Portal, M.E.5
Taguchi, T.6
Testa, J.R.7
Tsichlis, P.N.8
-
2
-
-
0030890933
-
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed, N.N., Grimes, H.L., Bellacosa, A., Chan, T.O., and Tsichlis, P.N. (1997). Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. USA 94, 3627-3632.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
3
-
-
0031913246
-
Mechanism of activation and function of protein kinase B
-
Alessi, D.R., and Cohen, P (1998). Mechanism of activation and function of protein kinase B. Curr. Opin. Gen. Dev. 8, 55-62.
-
(1998)
Curr. Opin. Gen. Dev.
, vol.8
, pp. 55-62
-
-
Alessi, D.R.1
Cohen, P.2
-
4
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi, D.R., Andjelkovic, M., Caudwell, B., Cron, P., Morrice, N., Cohen, P., and Hemmings, B.A. (1996). Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15, 6541-6551.
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
5
-
-
12644301164
-
3-Phosphoinositide-dependent protein kinase-1 (PDK1 ): Structural and functional homology with the Drosophila DSTPK61 kinase
-
Alessi, D.R., Deak, M., Casamayor, A., Caudwell, F.B., Morrice, N., Norman, D.G., Gaffney, P., Reese, C.B., MacDougall, C.N., Harbison, D., Ashworth, A., and Bownes, M. (1997). 3-phosphoinositide-dependent protein kinase-1 (PDK1 ): structural and functional homology with the Drosophila DSTPK61 kinase. Curr. Biol. 7, 776-789.
-
(1997)
Curr. Biol.
, vol.7
, pp. 776-789
-
-
Alessi, D.R.1
Deak, M.2
Casamayor, A.3
Caudwell, F.B.4
Morrice, N.5
Norman, D.G.6
Gaffney, P.7
Reese, C.B.8
Macdougall, C.N.9
Harbison, D.10
Ashworth, A.11
Bownes, M.12
-
6
-
-
0026095665
-
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
-
Bellacosa, A., Testa, J.R., Staar, S.P., and Tsichlis, P.N. (1991). A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science 254, 274-277.
-
(1991)
Science
, vol.254
, pp. 274-277
-
-
Bellacosa, A.1
Testa, J.R.2
Staar, S.P.3
Tsichlis, P.N.4
-
7
-
-
0029127042
-
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
-
Bellacosa, A., de Feo, D., Godwin, A.K., Bell, D.W., Cheng, J.Q., Altomare, D.A., Wan, M., Dubeau, L., Scambia, G., and Masciullo, V. (1995). Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int. J. Cancer 64, 280-285.
-
(1995)
Int. J. Cancer
, vol.64
, pp. 280-285
-
-
Bellacosa, A.1
De Feo, D.2
Godwin, A.K.3
Bell, D.W.4
Cheng, J.Q.5
Altomare, D.A.6
Wan, M.7
Dubeau, L.8
Scambia, G.9
Masciullo, V.10
-
8
-
-
0023857965
-
Specific chromosomal abnormalities in malignant human gliomas
-
Bigner, S.H., Mark, J., Burger, P.C., Mahaley, M.S. Jr., Bullard, D.E., Muhlbaier, L.H., and Bigner, D.D. (1998). Specific chromosomal abnormalities in malignant human gliomas. Cancer Res. 48, 405-411.
-
(1998)
Cancer Res.
, vol.48
, pp. 405-411
-
-
Bigner, S.H.1
Mark, J.2
Burger, P.C.3
Mahaley M.S., Jr.4
Bullard, D.E.5
Muhlbaier, L.H.6
Bigner, D.D.7
-
9
-
-
15444349266
-
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer
-
Cairns, P., Okami, K., Halachmi, S., Harachmi, N., Esteller, M., Herman, J.G., Jen, J., Isaacs, W.B., Bova, G.S., and Sidransky, D. (1997). Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res. 57, 4997-5000.
-
(1997)
Cancer Res.
, vol.57
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
Harachmi, N.4
Esteller, M.5
Herman, J.G.6
Jen, J.7
Isaacs, W.B.8
Bova, G.S.9
Sidransky, D.10
-
10
-
-
0026558609
-
EGF receptor amplification and expression in human brain tumours
-
Chaffanet, M., Chauvin, C., Laine, M., Berger, F., Chedin, M., Rost, N., Nissou, M.F., and Benabid, A.L. (1992). EGF receptor amplification and expression in human brain tumours. Eur. J. Cancer 28, 11-17.
-
(1992)
Eur. J. Cancer
, vol.28
, pp. 11-17
-
-
Chaffanet, M.1
Chauvin, C.2
Laine, M.3
Berger, F.4
Chedin, M.5
Rost, N.6
Nissou, M.F.7
Benabid, A.L.8
-
11
-
-
15644369261
-
Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer
-
Cheney, I.W., Johnson, D.E., Vaillancourt, M.T., Avanzini, J., Morimoto, A., Demers, G.W., Wills, K.N., Shabram, P.W., Bolen, J.B., Tavtigian, S.V., and Bookstein R. (1998). Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. Cancer Res. 58, 2331-2334.
-
(1998)
Cancer Res.
, vol.58
, pp. 2331-2334
-
-
Cheney, I.W.1
Johnson, D.E.2
Vaillancourt, M.T.3
Avanzini, J.4
Morimoto, A.5
Demers, G.W.6
Wills, K.N.7
Shabram, P.W.8
Bolen, J.B.9
Tavtigian, S.V.10
Bookstein, R.11
-
12
-
-
0026667730
-
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/ threonine kinases, is amplified in human ovarian carcinomas
-
Cheng, J.Q., Godwin, A.K., Bellacosa, A., Taguchi, T., Franke, T.F., Hamilton, T.C., Tsichlis, P.N., and Testa, J. R. (1992). AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/ threonine kinases, is amplified in human ovarian carcinomas. Proc. Natl. Acad. Sci. USA 89, 9267-9271.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9267-9271
-
-
Cheng, J.Q.1
Godwin, A.K.2
Bellacosa, A.3
Taguchi, T.4
Franke, T.F.5
Hamilton, T.C.6
Tsichlis, P.N.7
Testa, J.R.8
-
13
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
Cheng, J.Q., Ruggeri, B., Klein, W.M., Sonoda, G., Altomare, D.A., Watson, D.K., and Testa, J.R. (1996). Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc. Natl. Acad. Sci. USA 93, 3636-3641.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
Sonoda, G.4
Altomare, D.A.5
Watson, D.K.6
Testa, J.R.7
-
14
-
-
0028818755
-
Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo
-
Coucovanis, E., and Martin, G.R. (1995). Signals for death and survival: a two-step mechanism for cavitation in the vertebrate embryo. Cell 83, 279-287.
-
(1995)
Cell
, vol.83
, pp. 279-287
-
-
Coucovanis, E.1
Martin, G.R.2
-
15
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross, D.A., Alessi, D.R., Cohen, P., Andjelkovich, M., and Hemmings, B.A. (1995). Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
16
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward, J. (1998). Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell. Biol. 10, 262-267.
-
(1998)
Curr. Opin. Cell. Biol.
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
17
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase akt
-
Dudek, H., Datta, S.R., Franke, T.F., Birnbaum, M.J., Yao, R., Cooper, G.M., Segal, R.A., Kaplan, D.R., and Greenberg, M.E. (1997). Regulation of neuronal survival by the serine-threonine protein kinase akt. Science 275, 661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
18
-
-
0031883606
-
Genetics of Cowden syndrome: Through the looking glass of oncology
-
Eng, C. (1998). Genetics of Cowden syndrome: through the looking glass of oncology. Int. J. Oncol. 12, 701-710.
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 701-710
-
-
Eng, C.1
-
19
-
-
0030728479
-
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
-
Furnari, F.B., Lin, H., Huang, H.J.S., and Cavenee, W.K. (1997). Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc. Natl. Acad. Sci. USA 94, 12479-12484.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12479-12484
-
-
Furnari, F.B.1
Lin, H.2
Huang, H.J.S.3
Cavenee, W.K.4
-
20
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli, Y., Sherman, Y., and Ben-Sasson, S.A. (1992). Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
21
-
-
0004009318
-
Culture and biochemical analysis of cells
-
D.L. Spector, R.D. Goldman, and L.A. Leinwand, eds. (Plainview, New York: Cold Spring Harbor Laboratory Press)
-
Goldman, A. (1998). Culture and biochemical analysis of cells. In Cells: A Laboratory Manual, D.L. Spector, R.D. Goldman, and L.A. Leinwand, eds. (Plainview, New York: Cold Spring Harbor Laboratory Press), 4.1-4.7.
-
(1998)
Cells: A Laboratory Manual
, pp. 41-47
-
-
Goldman, A.1
-
22
-
-
0039058167
-
Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B
-
Hausler, P., Papoff, G., Eramo, A., Reif, K., Cantrell, D.A., and Ruberti, G. (1998). Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B. Eur. J. Immunol. 28, 57-69.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 57-69
-
-
Hausler, P.1
Papoff, G.2
Eramo, A.3
Reif, K.4
Cantrell, D.A.5
Ruberti, G.6
-
23
-
-
0023944129
-
Effects of fixation time and enzymatic digestion in immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue
-
Hayashi, Y., Koike, M., Matsunami, M., and Hoshino, T. (1988). Effects of fixation time and enzymatic digestion in immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue. J. Histochem. Cytochem. 36, 511-514.
-
(1988)
J. Histochem. Cytochem.
, vol.36
, pp. 511-514
-
-
Hayashi, Y.1
Koike, M.2
Matsunami, M.3
Hoshino, T.4
-
24
-
-
0032055478
-
Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells
-
Hitoshi, Y., Lorens, J., Kitada, S.I., Fisher, J., LaBarge, M., Ring, H.Z., Francke, U., Reed, J.C., Kinoshita, S., and Nolan, G.P. (1998). Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Immunity 8, 461-471.
-
(1998)
Immunity
, vol.8
, pp. 461-471
-
-
Hitoshi, Y.1
Lorens, J.2
Kitada, S.I.3
Fisher, J.4
Labarge, M.5
Ring, H.Z.6
Francke, U.7
Reed, J.C.8
Kinoshita, S.9
Nolan, G.P.10
-
25
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signaling through PI(3)K and PKB
-
Kauffmann-Zeh, A., Rodriguez-Viciana, P., Ulrich, E., Gilbert, C. Coffer, P., Downward, J., and Evan, G. (1997). Suppression of c-Myc-induced apoptosis by Ras signaling through PI(3)K and PKB. Nature 385, 544-548.
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffmann-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.C.P.4
Downward, J.5
Evan, G.6
-
26
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
Kennedy, S.G., Wagner, A.J., Conzen, S.D., Jordan, J., Bellacosa, A., Tsichlis, P.N., and Hay, N. (1997). The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev. 11, 701-713.
-
(1997)
Genes Dev.
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
Jordan, J.4
Bellacosa, A.5
Tsichlis, P.N.6
Hay, N.7
-
27
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja, A., Rodriguez-Viciana, P., Wennstrom, S., Warne, P.H., and Downward, J. (1997). Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16, 2783-2793.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
28
-
-
0032524104
-
Landscaping the cancer terrain
-
Kinzler, K.W., and Vogelstein, B. (1998). Landscaping the cancer terrain. Science 280, 1036-1037.
-
(1998)
Science
, vol.280
, pp. 1036-1037
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
29
-
-
0031034574
-
Antiapoptotic signaling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
-
Kulik, G., Klippel, A., and Weber, M.J. (1997). Antiapoptotic signaling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell. Biol. 17, 1595-1606.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1595-1606
-
-
Kulik, G.1
Klippel, A.2
Weber, M.J.3
-
30
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis, J.M., and Avruch, J. (1996). Sounding the alarm: protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 271, 24313-24316.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
31
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β
-
Li, D.-M., and Sun, H. (1997). TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β. Cancer Res. 57, 2124-2129.
-
(1997)
Cancer Res.
, vol.57
, pp. 2124-2129
-
-
Li, D.-M.1
Sun, H.2
-
32
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S.I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., et al. (1997). PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275, 1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
-
33
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D., Marsh, D.J., Li, J., Dahia, P.L.M., Wang, S.I., Zheng, Z., Bose, S., Call, K.M., Tsou, H.C., Peacocke, M., Eng, C., and Parsons, R. (1997). Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet. 16, 64-67.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.M.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
Eng, C.11
Parsons, R.12
-
34
-
-
0028533592
-
Tensin: A potential link between the cytoskeleton and signal transduction
-
Lo, S.H., Weisberg, E., and Chen, L.B. (1994). Tensin: a potential link between the cytoskeleton and signal transduction. Bioessays 16, 817-823.
-
(1994)
Bioessays
, vol.16
, pp. 817-823
-
-
Lo, S.H.1
Weisberg, E.2
Chen, L.B.3
-
35
-
-
0032577699
-
The tumor suppressor, PTEN/ MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama, T., and Dixon, J.E. (1998). The tumor suppressor, PTEN/ MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273, 13375-13378.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
36
-
-
6844252284
-
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
-
Marsh, D.J., Coulon, V., Lunetta, K.L., Rocca-Serra, P., Dahia, P.L.M., Zheng, Z., Liaw, D., Caron, S., Duboue, B., Lin, A.Y., et al. (1998). Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum. Mol. Genet. 7, 507-515.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 507-515
-
-
Marsh, D.J.1
Coulon, V.2
Lunetta, K.L.3
Rocca-Serra, P.4
Dahia, P.L.M.5
Zheng, Z.6
Liaw, D.7
Caron, S.8
Duboue, B.9
Lin, A.Y.10
-
37
-
-
0030727172
-
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase B beta
-
Meier, R., Alessi, D.R., Cron, P., Andjelkovic, M., and Hemmings, B.A. (1997). Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase B beta. J. Biol. Chem. 272, 30491-30497.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30491-30497
-
-
Meier, R.1
Alessi, D.R.2
Cron, P.3
Andjelkovic, M.4
Hemmings, B.A.5
-
38
-
-
6244256053
-
BMPR encodes a type 1 bone morphogenetic protein-receptor that is essential for gastrulation during mouse embryogenesis
-
Mishina, Y., Sukuki, A., Veno, N., and Behringer, R.R. (1995). BMPR encodes a type 1 bone morphogenetic protein-receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev. 9, 3027-3037.
-
(1995)
Genes Dev.
, vol.9
, pp. 3027-3037
-
-
Mishina, Y.1
Sukuki, A.2
Veno, N.3
Behringer, R.R.4
-
39
-
-
0030837555
-
PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers, M.P., Stolarov, J.P., Eng, C., Li, J., Wang, S.I., Wigler, M.H., Parsons, R., and Tonks, N.K. (1997). PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc. Natl. Acad. Sci. USA 94, 9052-9057.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
40
-
-
0031029214
-
Stress-signaling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3
-
Nishina, H., Fischer, K.D., Radvanyi, L., Shahinian, A., Hakem, R., Rubie, E.A., Bernstein, A., Mak, T.W., Woodgett, J.R., and Penninger, J. (1997). Stress-signaling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature 385, 350-353.
-
(1997)
Nature
, vol.385
, pp. 350-353
-
-
Nishina, H.1
Fischer, K.D.2
Radvanyi, L.3
Shahinian, A.4
Hakem, R.5
Rubie, E.A.6
Bernstein, A.7
Mak, T.W.8
Woodgett, J.R.9
Penninger, J.10
-
41
-
-
0030817576
-
PTEN gene mutations are seen in high-grade but not in low-grade gliomas
-
Rasheed, B.K.A., Stenzel, T.T., McLendon, R.E., Parsons, R., Friedman, A.H., Fridman, H.S., Bigner, D.D., and Bigner, S.H. (1997). PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res. 57, 4187-4190.
-
(1997)
Cancer Res.
, vol.57
, pp. 4187-4190
-
-
Rasheed, B.K.A.1
Stenzel, T.T.2
McLendon, R.E.3
Parsons, R.4
Friedman, A.H.5
Fridman, H.S.6
Bigner, D.D.7
Bigner, S.H.8
-
42
-
-
0030801275
-
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
-
Rhei, E., Kang, L., Bogomolniy, F., Federici, M.G., Borgen, P.I., and Boyd, J. (1997). Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res. 57, 3657-3659.
-
(1997)
Cancer Res.
, vol.57
, pp. 3657-3659
-
-
Rhei, E.1
Kang, L.2
Bogomolniy, F.3
Federici, M.G.4
Borgen, P.I.5
Boyd, J.6
-
43
-
-
0029870414
-
Focal adhesion kinase (p125FAK) and paxillin are substrates for sphingomyelinase-induced tyrosine phosphorylation in Swiss 3T3 fibroblasts
-
Sasaki, T., Hazeki, K., Hazeki, O., Ui, M., and Katada, T. (1996). Focal adhesion kinase (p125FAK) and paxillin are substrates for sphingomyelinase-induced tyrosine phosphorylation in Swiss 3T3 fibroblasts. Biochem. J. 315, 1035-1040.
-
(1996)
Biochem. J.
, vol.315
, pp. 1035-1040
-
-
Sasaki, T.1
Hazeki, K.2
Hazeki, O.3
Ui, M.4
Katada, T.5
-
44
-
-
0027979892
-
Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry
-
Schmid, I., Uittenbogaart, C.H., and Giorgi, J.V. (1994). Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry. Cytometry 15, 12-20.
-
(1994)
Cytometry
, vol.15
, pp. 12-20
-
-
Schmid, I.1
Uittenbogaart, C.H.2
Giorgi, J.V.3
-
45
-
-
0031958726
-
Platelet-derived growth factor (PDGF) in primary brain tumours of neuroglial origin
-
Smits, A., and Funa, K. (1998). Platelet-derived growth factor (PDGF) in primary brain tumours of neuroglial origin. Histol. Histopathol. 13, 511-520.
-
(1998)
Histol. Histopathol.
, vol.13
, pp. 511-520
-
-
Smits, A.1
Funa, K.2
-
46
-
-
0017739051
-
Gastrulation in the mouse: Growth and regionalization of the epiblast
-
Snow, M.H.L. (1977). Gastrulation in the mouse: growth and regionalization of the epiblast. J. Embryol. Exp. Morph. 42, 293-303.
-
(1977)
J. Embryol. Exp. Morph.
, vol.42
, pp. 293-303
-
-
Snow, M.H.L.1
-
47
-
-
0023945139
-
Thymic lymphoma induction by the AKT8 murine retrovirus
-
Staal, S.P., and Hartley, J.W. (1988). Thymic lymphoma induction by the AKT8 murine retrovirus. J. Exp. Med. 167, 1259-1264.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 1259-1264
-
-
Staal, S.P.1
Hartley, J.W.2
-
48
-
-
0032493029
-
Genetic analysis of protein kinase B (AKT) in Drosophila
-
Staveley, B.E., Ruel, L., Jin, J., Stambolic, V., Mastronardi, F.G., Heitzler, P., Woodgett, J.R., and Manoukian, A.S. (1998). Genetic analysis of protein kinase B (AKT) in Drosophila. Curr. Biol. 8, 599-602.
-
(1998)
Curr. Biol.
, vol.8
, pp. 599-602
-
-
Staveley, B.E.1
Ruel, L.2
Jin, J.3
Stambolic, V.4
Mastronardi, F.G.5
Heitzler, P.6
Woodgett, J.R.7
Manoukian, A.S.8
-
49
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck, P.A., Pershouse, M.A., Jasser, S.A., Yung, W.K.A., Lin, H., Ligon, A.H., Langford, L.A., Baumgard, M.L., Hattier, T., Davis, T., et al. (1997). Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet. 15, 356-362.
-
(1997)
Nat. Genet.
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.A.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
-
50
-
-
0032578999
-
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
-
Stephens, L., Anderson, K., Stokoe, D., ErdjumentBromage, H., Painter, G.F., Holmes, A.B., Gaffney, P.R.J., Reese, C.B., McCormick, F., Tempst, P., Coadwell, J., and Hawkins, P.T. (1998). Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 279, 710-714.
-
(1998)
Science
, vol.279
, pp. 710-714
-
-
Stephens, L.1
Anderson, K.2
Stokoe, D.3
Erdjumentbromage, H.4
Painter, G.F.5
Holmes, A.B.6
Gaffney, P.R.J.7
Reese, C.B.8
McCormick, F.9
Tempst, P.10
Coadwell, J.11
Hawkins, P.T.12
-
51
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
Stokoe, D., Stephens, L.R., Copeland, T., Gaffney, P.R., Reese, C.B., Painter, G.F., Holmes, A.B., McCormick, F., and Hawkins, P.T. (1997). Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science 277, 567-570.
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
52
-
-
0029091682
-
Identification and characterization of a fibroblast marker: FSP1
-
Strutz, F., Okada, H., Lo, C.W., Danoff, T., Carone, R.L., Tomaszevski, J.E., and Neilson, E.G. (1995) Identification and characterization of a fibroblast marker: FSP1. J. Cell Biol. 130, 393-405.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 393-405
-
-
Strutz, F.1
Okada, H.2
Lo, C.W.3
Danoff, T.4
Carone, R.L.5
Tomaszevski, J.E.6
Neilson, E.G.7
-
53
-
-
0026608650
-
Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas
-
Takahashi, J.A., Fukumoto, M., Igarashi, K., Oda, Y., Kikuchi, H., and Hatanaka, M. (1992). Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas. J. Neurosurg. 76, 792-798.
-
(1992)
J. Neurosurg.
, vol.76
, pp. 792-798
-
-
Takahashi, J.A.1
Fukumoto, M.2
Igarashi, K.3
Oda, Y.4
Kikuchi, H.5
Hatanaka, M.6
-
54
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R., and Yamada, K.M. (1998). Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280, 1614-1617.
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
55
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro, H., Blazes, M.S., Wu, R., Cho, K.R., Bose, S., Wang, S.I., Li, J., Parsons, R., and Ellenson, L.H. (1997). Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res. 57, 3935-3940.
-
(1997)
Cancer Res.
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
Cho, K.R.4
Bose, S.5
Wang, S.I.L.J.6
Parsons, R.7
Ellenson, L.H.8
-
56
-
-
14444269482
-
MMAC1/ PTEN mutations in primary tumor specimens and tumor cell lines
-
Teng, D.H-F., Hu, R., Lin, H., Davis, T., Illiev, D., Frye, C., Swedlund, B., Hansen, K.L., Vinson, V.L., Gumpper, K.L., et al. (1997). MMAC1/ PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res. 57, 5221-5225.
-
(1997)
Cancer Res.
, vol.57
, pp. 5221-5225
-
-
Teng, D.H.-F.1
Hu, R.2
Lin, H.3
Davis, T.4
Illiev, D.5
Frye, C.6
Swedlund, B.7
Hansen, K.L.8
Vinson, V.L.9
Gumpper, K.L.10
-
57
-
-
0032546030
-
Specific TrkA survival signals interfere with different apoptotic pathways
-
Ulrich, E., Duwel, A., Kauffmann-Zeh, A., Gilbert, C., Lyon, D., Rudkin, B., Evan, G., and Martin-Zanca, D. (1998). Specific TrkA survival signals interfere with different apoptotic pathways. Oncogene 16, 825-832.
-
(1998)
Oncogene
, vol.16
, pp. 825-832
-
-
Ulrich, E.1
Duwel, A.2
Kauffmann-Zeh, A.3
Gilbert, C.4
Lyon, D.5
Rudkin, B.6
Evan, G.7
Martin-Zanca, D.8
-
58
-
-
0032079523
-
Protein kinase B and Rac are activated in parallel within a phosphatidylinositide 3OH-kinase-controlled signaling pathway
-
Welch, H., Eguinoa, A., Stephens, L.A., and Hawkins, P.T. (1998). Protein kinase B and Rac are activated in parallel within a phosphatidylinositide 3OH-kinase-controlled signaling pathway. J. Biol. Chem. 273, 11248-11256.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11248-11256
-
-
Welch, H.1
Eguinoa, A.2
Stephens, L.A.3
Hawkins, P.T.4
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