Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

Diabetologia

Volumn 41, Issue 12, 1998, Pages 1511-1515

  Hani, E H ^a   Boutin, P ^a   Durand, E ^a   Inoue, H ^b   Permutt, M A ^b   Velho, G ^c   Froguel, P ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HÔPITAL SAINT VINCENT DE PAUL   (France)

Author keywords

Gene; Inwardly rectifier potassium channel; Mutation; Type II (non insulin dependent) diabetes mellitus

Indexed keywords

POTASSIUM CHANNEL;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; FEMALE; GENE EXPRESSION; GENETIC DISORDER; GENOTYPE; HOMOZYGOSITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; MISSENSE MUTATION; MULTIFACTORIAL INHERITANCE; PANCREAS ISLET CELL; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

AGED; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; FRANCE; GENE FREQUENCY; HETEROZYGOTE; HOMOZYGOTE; HUMANS; ISLETS OF LANGERHANS; MALE; MIDDLE AGED; MUTATION, MISSENSE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; POTASSIUM CHANNELS;

EID: 0031773333     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051098     Document Type: Article

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