메뉴 건너뛰기




Volumn 102, Issue 1, 1998, Pages 232-241

Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein

Author keywords

Gene transactivation; Internal translation; Mutated allele

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 0032128288     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2242     Document Type: Article
Times cited : (163)

References (34)
  • 1
    • 0016641270 scopus 로고
    • A difference between inheritance of classical juvenile-onset and maturity-onset type diabetes of young people
    • Tattersall, R.B., and S.S. Fajans. 1975. A difference between inheritance of classical juvenile-onset and maturity-onset type diabetes of young people. Diabetes. 24:44-53.
    • (1975) Diabetes , vol.24 , pp. 44-53
    • Tattersall, R.B.1    Fajans, S.S.2
  • 4
    • 0031253820 scopus 로고    scopus 로고
    • Early-onset type-II diabetes mellitus (MODY4) linked to IPF-1
    • Stoffers, D.A., J. Ferrer, W.L. Clarke, and J.F. Habener. 1997. Early-onset type-II diabetes mellitus (MODY4) linked to IPF-1. Nat. Genet. 17:138-134.
    • (1997) Nat. Genet. , vol.17 , pp. 138-1134
    • Stoffers, D.A.1    Ferrer, J.2    Clarke, W.L.3    Habener, J.F.4
  • 6
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson, J., L. Carlsson, T. Edlund, and H. Edlund. 1994. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature. 371:606-609.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 7
    • 0031031571 scopus 로고    scopus 로고
    • Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 coding region
    • Stoffers, D.A., N.T. Zinkin, V. Stanojevic, W.L. Clarke, and J.F. Habener. 1997. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 coding region. Nat. Genet. 15:106-110.
    • (1997) Nat. Genet. , vol.15 , pp. 106-110
    • Stoffers, D.A.1    Zinkin, N.T.2    Stanojevic, V.3    Clarke, W.L.4    Habener, J.F.5
  • 8
    • 0027154077 scopus 로고
    • Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters
    • Melloul, D., Y. Ben-Neriah, and E. Cerasi. 1993. Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters. Proc. Natl. Acad. Sci. USA. 90:3865-3869.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3865-3869
    • Melloul, D.1    Ben-Neriah, Y.2    Cerasi, E.3
  • 9
    • 0028006811 scopus 로고
    • Glucose modulates the binding activity of the β cell transcription factor IUF-1 in a phosphorylalion-dependent manner
    • MacFarlane, W., M.L. Read, M. Gilligan, I. Bujalska, and K. Docherty. 1994. Glucose modulates the binding activity of the β cell transcription factor IUF-1 in a phosphorylalion-dependent manner. Biochem. J. 303:625-631.
    • (1994) Biochem. J. , vol.303 , pp. 625-631
    • MacFarlane, W.1    Read, M.L.2    Gilligan, M.3    Bujalska, I.4    Docherty, K.5
  • 10
    • 0030447883 scopus 로고    scopus 로고
    • Purification of the β-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells
    • Marshak, S., H. Totary, E. Cerasi, and D. Melloul. 1996. Purification of the β-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells. Proc. Natl. Acad. Sci. USA. 93: 15057-15062.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15057-15062
    • Marshak, S.1    Totary, H.2    Cerasi, E.3    Melloul, D.4
  • 11
    • 0030457705 scopus 로고    scopus 로고
    • Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor
    • Waeber, G., N. Thompson, P. Nicod, and C. Bonny. 1996. Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor. Mol. Endocrinol. 10:1327-1334.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 1327-1334
    • Waeber, G.1    Thompson, N.2    Nicod, P.3    Bonny, C.4
  • 12
    • 0029909387 scopus 로고    scopus 로고
    • The human glucokinase gene β-cell-type promoter: An essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells
    • Watada, H., Y. Kajimoto, Y. Umayahara, T. Matsuoka, H. Kaneto, Y. Fujitani, T. Kamada, R. Kawamori, and Y. Yamasaki. 1996. The human glucokinase gene β-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells. Diabetes. 45:1478-1488.
    • (1996) Diabetes , vol.45 , pp. 1478-1488
    • Watada, H.1    Kajimoto, Y.2    Umayahara, Y.3    Matsuoka, T.4    Kaneto, H.5    Fujitani, Y.6    Kamada, T.7    Kawamori, R.8    Yamasaki, Y.9
  • 13
    • 0031007661 scopus 로고    scopus 로고
    • Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic β-cells
    • Carty, M.D., J.S. Lillquist, M. Peshavaria, R. Stein, and W.C. Soeller. 1997. Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic β-cells. J. Biol. Chem. 272: 11986-11993.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11986-11993
    • Carty, M.D.1    Lillquist, J.S.2    Peshavaria, M.3    Stein, R.4    Soeller, W.C.5
  • 14
    • 0030003314 scopus 로고    scopus 로고
    • Functional regions of the homeodomain protein IDX-1 required for transactivation of the rat somatostatin gene
    • Lu, M., C.P. Miller, and J.F. Habener. 1996. Functional regions of the homeodomain protein IDX-1 required for transactivation of the rat somatostatin gene. Endocrinology. 137:2959-2967.
    • (1996) Endocrinology , vol.137 , pp. 2959-2967
    • Lu, M.1    Miller, C.P.2    Habener, J.F.3
  • 15
    • 0028567837 scopus 로고
    • Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1
    • Peers, B., J. Leonard, S. Sharma, G. Teitelman, and M.R. Montminy. 1994. Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol. Endocrinol. 8:1798-1806.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1798-1806
    • Peers, B.1    Leonard, J.2    Sharma, S.3    Teitelman, G.4    Montminy, M.R.5
  • 16
    • 0030907390 scopus 로고    scopus 로고
    • Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1
    • Sharma, S., U.S. Jhala, T. Johnson, K. Ferreri, J. Leonard, and M. Montminy. 1997. Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1. Mol. Cell Biol. 17:2598-2604.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 2598-2604
    • Sharma, S.1    Jhala, U.S.2    Johnson, T.3    Ferreri, K.4    Leonard, J.5    Montminy, M.6
  • 17
    • 0028314969 scopus 로고
    • IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
    • Miller, C.P., R. McGehee, and J.F. Habener. 1994. IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO (Eur. Mol. Biol. Organ.) J. 13:1145-1156.
    • (1994) EMBO (Eur. Mol. Biol. Organ.) J. , vol.13 , pp. 1145-1156
    • Miller, C.P.1    McGehee, R.2    Habener, J.F.3
  • 18
    • 0026602931 scopus 로고
    • The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes
    • German, M.S., L.G. Moss, J. Wang, and W.J. Rutter. 1992. The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes. Mol. Cell Biol. 12:1777-1788.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 1777-1788
    • German, M.S.1    Moss, L.G.2    Wang, J.3    Rutter, W.J.4
  • 20
    • 0026776285 scopus 로고
    • Somatostatin gene upstream enhancer element activated by a protein complex consisting of CREB, Isl-1-Iike, and alpha-CBF-like transcription factors
    • Vallejo, M., L. Penchuk, and J.F. Habener. 1992. Somatostatin gene upstream enhancer element activated by a protein complex consisting of CREB, Isl-1-Iike, and alpha-CBF-like transcription factors. J. Biol. Chem. 267:12876-12884.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12876-12884
    • Vallejo, M.1    Penchuk, L.2    Habener, J.F.3
  • 21
    • 0024546509 scopus 로고
    • The scanning model for translation: An update
    • Kozak, M. 1989. The scanning model for translation: an update. J. Cell Biol. 108:229-241.
    • (1989) J. Cell Biol. , vol.108 , pp. 229-241
    • Kozak, M.1
  • 22
    • 0027373441 scopus 로고
    • Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
    • Leonard, J., B. Peers, T. Johnson, K. Ferreri, S. Lee, and M.R. Montminy. 1993. Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol. Endocrinol. 7:1275-1283.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1275-1283
    • Leonard, J.1    Peers, B.2    Johnson, T.3    Ferreri, K.4    Lee, S.5    Montminy, M.R.6
  • 23
    • 0029786309 scopus 로고    scopus 로고
    • Alternative exon splicing controls a translational switch from activator to repressor isoforms of transcription factor CREB during spermatogenesis
    • Walker, W.H., C. Girardet, and J.F. Habener. 1996. Alternative exon splicing controls a translational switch from activator to repressor isoforms of transcription factor CREB during spermatogenesis. J. Biol. Chem. 271:20145-20150.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20145-20150
    • Walker, W.H.1    Girardet, C.2    Habener, J.F.3
  • 24
    • 0028914004 scopus 로고
    • Adherence to the first-AUG rule when a second AUG codon follows closely upon the first
    • Kozak, M. 1993. Adherence to the first-AUG rule when a second AUG codon follows closely upon the first. Proc. Natl. Acad. Sci. USA. 92:2662-2666.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2662-2666
    • Kozak, M.1
  • 25
    • 1842335136 scopus 로고    scopus 로고
    • Translation of an uncapped mRNA involves scanning
    • Gunnery, S., U. Maivali, and M.B. Mathews. 1997. Translation of an uncapped mRNA involves scanning. J. Biol. Chem. 272:21642-21646.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21642-21646
    • Gunnery, S.1    Maivali, U.2    Mathews, M.B.3
  • 26
    • 0002568139 scopus 로고    scopus 로고
    • A comparative view of initiation site selection mechanisms
    • J.W.B. Hershey, M.B. Mathews, and N. Sonenberg, editors. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Jackson, R.J. 1996. A comparative view of initiation site selection mechanisms. In Translational Control. J.W.B. Hershey, M.B. Mathews, and N. Sonenberg, editors. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 71-112.
    • (1996) Translational Control , pp. 71-112
    • Jackson, R.J.1
  • 27
    • 0002261007 scopus 로고    scopus 로고
    • Translational control mediated by upstream AUG codons
    • J.W.B. Hershey, M.B. Mathews, and N. Sonenberg, editors. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Geballe, A.P. 1996. Translational control mediated by upstream AUG codons. In Translational Control. J.W.B. Hershey, M.B. Mathews, and N. Sonenberg, editors. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 173-198.
    • (1996) Translational Control , pp. 173-198
    • Geballe, A.P.1
  • 28
    • 0026480387 scopus 로고
    • Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses
    • Baniahmad, A., S.Y. Tsai, B.W. O'Malley, and M.-J. Tsai. 1992. Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses. Proc. Natl. Acad. Sci. USA. 89:10633-10637.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10633-10637
    • Baniahmad, A.1    Tsai, S.Y.2    O'Malley, B.W.3    Tsai, M.-J.4
  • 29
    • 0026767630 scopus 로고
    • A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency
    • Radovick, S., M. Nations, Y. Du, L.A. Berg, B.D. Weintraub, and F.E. Wondisford. 1992. A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency. Science. 257:1115-1117.
    • (1992) Science , vol.257 , pp. 1115-1117
    • Radovick, S.1    Nations, M.2    Du, Y.3    Berg, L.A.4    Weintraub, B.D.5    Wondisford, F.E.6
  • 31
    • 0029177811 scopus 로고
    • Age-dependent reduction in insulin secretion and insulin mRNA in isolated islets from rats
    • Perfetti, R., C. Montrose-Rafizadeh, A.S. Liotta, and J.M. Egan. 1995. Age-dependent reduction in insulin secretion and insulin mRNA in isolated islets from rats. Am. J. Physiol. 269:E983-E990.
    • (1995) Am. J. Physiol. , vol.269
    • Perfetti, R.1    Montrose-Rafizadeh, C.2    Liotta, A.S.3    Egan, J.M.4
  • 32
    • 4243983712 scopus 로고    scopus 로고
    • Expression of homeodomain factor IDX-1 in pancreas and duodenum: Discordance among expression of an IDX-1 β-galactosidase transcriptional reporter. IDX-1 mRNA and protein
    • Abstr.
    • Stoffers, D.A., R.S. Heller, C.P. Miller, and J.F. Habener. 1996. Expression of homeodomain factor IDX-1 in pancreas and duodenum: discordance among expression of an IDX-1 β-galactosidase transcriptional reporter. IDX-1 mRNA and protein. 10th Int. Cong. Endocrinol. P2-35(Abstr.).
    • (1996) 10th Int. Cong. Endocrinol.
    • Stoffers, D.A.1    Heller, R.S.2    Miller, C.P.3    Habener, J.F.4
  • 33
    • 0028987251 scopus 로고
    • Dynamics of β-cell mass in the growing rat pancreas: Estimation with a simple mathematical model
    • Finegood, D.T., L. Scaglia, and S. Bonner-Weir. 1995. Dynamics of β-cell mass in the growing rat pancreas: estimation with a simple mathematical model. Diabetes. 44:249-256.
    • (1995) Diabetes , vol.44 , pp. 249-256
    • Finegood, D.T.1    Scaglia, L.2    Bonner-Weir, S.3
  • 34
    • 0031985396 scopus 로고    scopus 로고
    • A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus
    • Habener, J., and D. Stoffers. 1998. A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus. Proc. Assoc. Am. Phys. 110:12-21.
    • (1998) Proc. Assoc. Am. Phys. , vol.110 , pp. 12-21
    • Habener, J.1    Stoffers, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.