Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action

Journal of Clinical Investigation

Volumn 98, Issue 10, 1996, Pages 2346-2350

  Thompson, D Bruce ^a   Pratley, Richard ^a   Ossowski, Victoria ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

cell culture; glycogen; insulin; myoblast; skeletal muscle

Indexed keywords

ALPHA ACTININ; CREATINE KINASE; INSULIN; MYOSIN; RNA;

ADULT; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; DOSE RESPONSE; GLYCOGEN METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERINSULINEMIA; INSULIN METABOLISM; INSULIN RESISTANCE; MUSCLE BIOPSY; MYOBLAST; PHENOTYPE; PRIORITY JOURNAL; SKELETAL MUSCLE;

EID: 0029807640     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119046     Document Type: Article

References (20)

1. DeFronzo, R.A., R.C. Bonadonna, and E. Ferrannini. 1992. Pathogenesis if NIDDM. Diabetes Care. 15:318-367.
2. 13C nuclear magnetic resonance spectroscopy. N. Engl. J. Med. 322:223-228.
3. 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. J. Clin. Invest. 89:1069-1075.
4. Beck-Nielson, H., and L.C. Groop. 1994. Metabolic and genetic characterization of prediabetic states. J. Clin. Invest. 94:1714-1721.
5. Yasin, R., G. Van Beers, K.C.E. Jurse, S. Al-ani, D.N. Landon, and E.J. Thompson. 1977. A quantitative technique for growing human adult skeletal muscle in culture starting from mononucleated cells. J. Neuro. Sci. 32:347-360.
6. Henry, R.R., L. Abrams, S. Nikoulina, and T.P. Ciaraldi. 1995. Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Diabetes. 44:936-946.
7. Bogardus, C., S. Lillioja, K. Stone, and D. Mott. 1984. Correlation between muscle glycogen synthase activity and in vivo insulin action in man. J. Clin. Invest. 73:1185-1190.
8. Bobek, G., C.D. Scott, and R.C. Baxter. 1991. Secretion of soluble insulin-like growth factor-II/mannose 6-phosphate receptor by rat tissues in culture. Endocrinology. 128:2204-2207.
9. Howard, B.V., R.M. Fields, D.M. Mott, P.J. Savage, M. Nagulesparan, and P.M. Bennett. 1980. Diabetes and cell growth-lack of differences in growth characteristics of fibroblasts from diabetic and nondiabetic Pima Indians. Diabetes. 29:119-124.
10. Van der Ven, P.F.M., G. Schaart, P.H.K. Jap, R.C.A. Sengers, A.M. Stadhouders, and F.C.S. Ramaekers. 1992. Differentiation of human skeletal muscle cells in culture: maturation as indicated by titin and desmin striation. Cell Tissue Res. 270:189-198.
11. Maniatis, T., E.F. Fritsch, and J. Sambrook. 1982. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
12. Howard, B.V., H. Hidaka, F. Ishibashi, R. Fields, and P.H. Bennett. 1981. Type II diabetes and insulin resistance; evidence for lack of inherent cellular defects in insulin sensitivity. Diabetes. 30:562-567.
13. Burant, C.F., S.K. Lemmon, M.K. Treutelaar, and M.G. Buse. 1984. Insulin resistance of denervated rat muscle: a model for impaired receptor-function coupling. Am. J. Physiol. 247:E657-E666.
14. Bensadoun, A., and D. Weinstein. 1976. Assay of proteins in the presence of interfering materials. Anal. Biochem. 70:241-250.
15. Sasson, S., and E. Cerasi. 1986. Substrate regulation of the glucose transport system in rat skeletal muscle. J. Biol. Chem. 261:16827-16833.
16. Sarabia, V., L. Lam, E. Burdett, L.A. Leiter, and A. Klip. 1992. Glucose transport in human skeletal muscle cells in culture. J. Clin. Invest. 90:1386-1395.
17. Furth, P.A., A. Shamay, R.J. Wall, and L. Hennighausen. 1992. Gene transfer into somatic tissues by jet injection. Anal. Biochem. 205:365-368.
18. Rossetti, L., A. Giaccari, and R.A. DeFronzo. 1990. Glucose toxicity. Diabetes Care. 13:610-630.
19. Ciaraldi, T.P., L. Abrams, S. Nikoulina, S. Mudaliar, and R.R. Henry. 1995. Glucose transport in cultured human skeletal muscle cells. J. Clin. Invest. 96:2820-2827.
20. Lillioja, S., D.M. Mott, M. Spraul, R. Ferraro, J.E. Foley, E. Ravussin, W.C. Knowler, P.H. Bennett, and C. Bogardus. 1993. Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. N. Engl. J. Med. 329:1988-1992.