Role of cholesterol in APP metabolism and its significance in Alzheimer's disease pathogenesis

Molecular Neurobiology

Volumn 47, Issue 1, 2013, Pages 37-63

  Maulik, M ^a,b   Westaway, D ^a,b   Jhamandas, J H ^a,b   Kar, S ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Lipid rafts; Neuronal cholesterol level distribution; Neurotoxicity; Amyloid peptide

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; CHOLESTEROL; STEROL REGULATORY ELEMENT BINDING PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DNA POLYMORPHISM; ENDOSOME; FEMALE; GOLGI COMPLEX; HOMEOSTASIS; IN VIVO STUDY; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN METABOLISM; REVIEW;

EID: 84872498729     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-012-8337-y     Document Type: Review

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