메뉴 건너뛰기




Volumn 21, Issue , 1998, Pages 479-505

Mutant genes in familial Alzheimer's disease and transgenic models

Author keywords

A deposition; Amyloid precursor protein; Function; Metabolism; Presenilins

Indexed keywords

ALLELE; ALZHEIMER DISEASE; GENE MUTATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; NERVE CELL NECROSIS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; RISK FACTOR; TRANSGENIC ANIMAL;

EID: 0031921466     PISSN: 0147006X     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.neuro.21.1.479     Document Type: Review
Times cited : (516)

References (19)
  • 2
    • 0000174463 scopus 로고
    • Über eine eigenartige Erkrankung der Hirnrinde
    • Alzheimer A. 1907b. Über eine eigenartige Erkrankung der Hirnrinde. Zentralbl. Nervenheilkd. Psychiatr. 30:177-79
    • (1907) Zentralbl. Nervenheilkd. Psychiatr. , vol.30 , pp. 177-179
    • Alzheimer, A.1
  • 3
    • 0029115555 scopus 로고
    • The structure of the presenilin l (S182) gene and identification of six novel mutations in early onset AD families
    • Alzheimer's Disease Collaborative Group. 1995. The structure of the presenilin l (S182) gene and identification of six novel mutations in early onset AD families. Nature Genet. 11:219-22
    • (1995) Nature Genet. , vol.11 , pp. 219-222
  • 4
    • 0025717816 scopus 로고
    • The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease
    • Arnold SE, Hyman BT, Flory J, Damasio AR, Van Hoesen GW. 1991. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb. Cortex 1:103-16
    • (1991) Cereb. Cortex , vol.1 , pp. 103-116
    • Arnold, S.E.1    Hyman, B.T.2    Flory, J.3    Damasio, A.R.4    Van Hoesen, G.W.5
  • 6
    • 0031108103 scopus 로고    scopus 로고
    • Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing
    • In press
    • Baumeister R, Leimer U, Zweckbronner I, Jakubek C, Grünberg J, Haass C. 1997. Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing. Genes Funct. In press
    • (1997) Genes Funct.
    • Baumeister, R.1    Leimer, U.2    Zweckbronner, I.3    Jakubek, C.4    Grünberg, J.5    Haass, C.6
  • 7
    • 0030833055 scopus 로고    scopus 로고
    • Accelerated amyloid deposition in the brains of transgenic mice co-expressing mutant presenilin 1 and amyloid precursor proteins
    • Borchelt DR, Ratovitski T, Van Lare J, Lee MK, Gonzales VB, et al. 1997. Accelerated amyloid deposition in the brains of transgenic mice co-expressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19:939-45
    • (1997) Neuron , vol.19 , pp. 939-945
    • Borchelt, D.R.1    Ratovitski, T.2    Van Lare, J.3    Lee, M.K.4    Gonzales, V.B.5
  • 8
    • 0030293676 scopus 로고    scopus 로고
    • Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo
    • Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, et al. 1996. Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo. Neuron 17:1005-13
    • (1996) Neuron , vol.17 , pp. 1005-1013
    • Borchelt, D.R.1    Thinakaran, G.2    Eckman, C.B.3    Lee, M.K.4    Davenport, F.5
  • 9
    • 0001815909 scopus 로고
    • Pathology of Alzheimer's disease
    • ed. DB Calne, Philadelphia: Saunders
    • Braak H, Braak E. 1994. Pathology of Alzheimer's disease. In Neurodegenerative Diseases, ed. DB Calne, pp. 585-613 Philadelphia: Saunders
    • (1994) Neurodegenerative Diseases , pp. 585-613
    • Braak, H.1    Braak, E.2
  • 11
    • 0029163222 scopus 로고
    • SCAI transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat
    • Burright EN, Clark HB, Servadio A, Matilla T, Feddersen RM, et al. 1995, SCAI transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat. Cell 82:937-48
    • (1995) Cell , vol.82 , pp. 937-948
    • Burright, E.N.1    Clark, H.B.2    Servadio, A.3    Matilla, T.4    Feddersen, R.M.5
  • 14
    • 0026448114 scopus 로고
    • Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer β1A4 amyloid protein precursor
    • Buxbaum JD, Oishi M, Chen HI, Pinkas-Kramarski R, Jaffe EA, et al. 1992. Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer β1A4 amyloid protein precursor. Proc. Natl. Acad. Sci. USA 89:10075-78
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10075-10078
    • Buxbaum, J.D.1    Oishi, M.2    Chen, H.I.3    Pinkas-Kramarski, R.4    Jaffe, E.A.5
  • 15
    • 0028812820 scopus 로고
    • Mutations of the presenilin 1 gene in families with early-onset alzheimer's disease
    • Campion D, Flaman JM, Brice A, Hannequin D, Dubois B, et al. 1995. Mutations of the presenilin 1 gene in families with early-onset alzheimer's disease. Hum. Mol. Genet. 4:2373-77
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 2373-2377
    • Campion, D.1    Flaman, J.M.2    Brice, A.3    Hannequin, D.4    Dubois, B.5
  • 16
    • 0026075602 scopus 로고
    • Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
    • Chartier-Harlin M-C, Crawford F, Houlden H, Warren A, Hughes D, et al. 1991. Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene. Nature 353:844-46
    • (1991) Nature , vol.353 , pp. 844-846
    • Chartier-Harlin, M.-C.1    Crawford, F.2    Houlden, H.3    Warren, A.4    Hughes, D.5
  • 17
    • 0029896354 scopus 로고    scopus 로고
    • Mechanisms of neuronal degeneration in Alzheimer's disease
    • Yankner BA. 1996. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 16:921-32
    • (1996) Neuron , vol.16 , pp. 921-932
    • Yankner, B.A.1
  • 18
    • 0028988801 scopus 로고
    • β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
    • Zheng H, Jiang M-H, Trumbauer ME, Sirinathsinghji DJS, Hopkins R, et al. 1995. β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell 81:525-31
    • (1995) Cell , vol.81 , pp. 525-531
    • Zheng, H.1    Jiang, M.-H.2    Trumbauer, M.E.3    Sirinathsinghji, D.J.S.4    Hopkins, R.5
  • 19
    • 0030788767 scopus 로고    scopus 로고
    • Presenilin 1 interaction in the brain with a novel member of the armadillo family
    • In press
    • Zhou J, Liyanage U, Medina M, Ho C, Simmons AD, et al. 1997. Presenilin 1 interaction in the brain with a novel member of the armadillo family. NeuroReport. In press
    • (1997) NeuroReport
    • Zhou, J.1    Liyanage, U.2    Medina, M.3    Ho, C.4    Simmons, A.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.