TGF-β1 promotes microglial amyloid-β clearance and reduces plaque burden in transgenic mice

Nature Medicine

Volumn 7, Issue 5, 2001, Pages 612-618

  Wyss Coray, Tony ^a,b   Lin, Carol ^a   Yan, Fengrong ^a   Yu, Gui Qiu ^a   Rohde, Michelle ^a   Mcconlogue, Lisa ^c   Masliah, Eliezer ^d   Mucke, Lennart ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ELAN PHARMACEUTICALS   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TGFB1 PROTEIN, HUMAN; TGFB1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTOSOMAL DOMINANT INHERITANCE; BRAIN BLOOD VESSEL; CONTROLLED STUDY; IMMUNOREACTIVITY; MACROPHAGE ACTIVATION; MESSENGER RNA SYNTHESIS; MOUSE; NEUROPROTECTION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRANSGENIC ANIMAL; AGED; ANIMAL; BLOOD VESSEL; BRAIN; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HUMAN; METABOLISM; MICROGLIA; MOLECULAR GENETICS; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

AGED; AGED, 80 AND OVER; AMYLOID BETA-PROTEIN; ANIMALS; BLOOD VESSELS; BRAIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MICE; MICE, TRANSGENIC; MICROGLIA; MOLECULAR SEQUENCE DATA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0034744296     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/87945     Document Type: Article

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