Neurons regulate extracellular levels of amyloid β-protein via proteolysis by insulin-degrading enzyme

Journal of Neuroscience

Volumn 20, Issue 5, 2000, Pages 1657-1665

  Vekrellis, Konstantinos ^a   Ye, Zhen ^a   Qiu, Wei Qiao ^a   Walsh, Dominic ^a   Hartley, Dean ^a   Chesneau, Valérie ^b   Rosner, Marsha Rich ^b   Selkoe, Dennis J ^a,c  

^a Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Amyloid protein degradation; Insulin degrading enzyme; Membrane proteins; Neurons; Oligomerization

Indexed keywords

AMYLOID BETA PROTEIN; CELL MEMBRANE PROTEIN; INSULINASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BIOTINYLATION; CELL CULTURE; CELL SURFACE; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME RELEASE; EXTRACELLULAR SPACE; NERVE CELL; NERVE CELL DIFFERENTIATION; NONHUMAN; OLIGOMERIZATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; RISK FACTOR;

EID: 0034161516     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-05-01657.2000     Document Type: Article

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