Genotype and phenotype in Alzheimer's disease

British Journal of Psychiatry

Volumn 180, Issue FEB., 2002, Pages 131-134

  Holmes, Clive ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; ALPHA 2 MACROGLOBULIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; CHOLINESTERASE; DIPEPTIDYL CARBOXYPEPTIDASE; DOPAMINE RECEPTOR; HLA ANTIGEN; INTERLEUKIN 1; PRESENILIN 1; PRESENILIN 2; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN TRANSPORTER; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

ALZHEIMER DISEASE; COGNITIVE DEFECT; DISEASE DURATION; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HUMAN; ONSET AGE; PHENOTYPE; REVIEW; RISK FACTOR; TWINS;

AGED; ALZHEIMER DISEASE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; PHENOTYPE; RISK FACTORS;

EID: 0036160489     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.180.2.131     Document Type: Review

References (20)

1. Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene
2. Wide range in age of onset for chromosome I-related familial Alzheimer's disease
3. Alpha-2 macroglobulin is genetically associated with Alzheimer's disease
4. A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia
5. Accelerated decline in apolipoprotein E-epsilon4 homozygotes with Alzheimer's disease
6. Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease
7. Linkage of plasma A β 42 to a quantitative locus on chromosome 10 in late onset Alzheimer's disease pedigrees
8. Promoter polymorphism (-491A/T) in the APOE gene of Finnish Alzheimer's disease patients and control individuals
9. 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease
10. A full genome scan for late onset Alzheimer's disease
11. Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease
12. APOE genotype predicts when - Not whether - One is predisposed to develop Alzheimer disease
13. Susceptibility locus for Alzheimer's disease on chromosome 10
14. Association between family history of affective disorder and the depressive syndrome of Alzheimer's disease
15. Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12
16. Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer's disease
17. Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease
18. A novel Polish presenilin-2 mutation (P117L) is associated with familial Alzheimer's disease and leads to death as early as the age of 28 years
19. Genetic studies on chromosome 12 in late-onset Alzheimer disease
20. APOE promoter polymorphisms do not confer independent risk for Alzheimer's disease in a French population