Novel N-terminal cleavage of APP precludes Aβ generation in ACAT-defective AC29 cells

Journal of Molecular Neuroscience

Volumn 37, Issue 1, 2009, Pages 6-15

  Huttunen, Henri J ^a   Puglielli, Luigi ^a,c   Ellis, Blake C ^a   MacKenzie Ingano, Laura A ^a,b   Kovacs, Dora M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Alzheimer's disease; Amyloid; Cholesterol

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; GLUTAMIC ACID; PROTEASOME; STEROL; STEROL O ACYLTRANSFERASE 1; STEROL O-ACYLTRANSFERASE 1;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FATE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOSOME; ENZYME ACTIVITY; ENZYME DEGRADATION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL; CHO CELL; CRICETULUS; ENDOCYTOSIS; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; METABOLISM; PHYSIOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOSIS; ANIMALS; CHO CELLS; CHOLESTEROL; CRICETINAE; CRICETULUS; ENDOCYTOSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; STEROL O-ACYLTRANSFERASE;

EID: 62649094607     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-008-9088-0     Document Type: Article

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