-
1
-
-
0032508675
-
TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3
-
(1998)
FEBS Lett.
, vol.435
, pp. 39-44
-
-
Amour, A.1
Slocombe, P.M.2
Webster, A.3
Butler, M.4
Knight, C.G.5
Smith, B.J.6
Stephens, P.E.7
Shelley, C.8
Hutton, M.9
Knauper, V.10
Docherty, A.J.11
Murphy, G.12
-
8
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
12
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
(1998)
Nat. Med.
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
13
-
-
0032568843
-
Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
Maeda, N.7
Siman, R.8
Greenberg, B.D.9
Scott, R.W.10
Flood, D.G.11
-
14
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
17
-
-
0027971798
-
Genetic influences on age related change in total cholesterol low density lipoprotein cholesterol, triglyceride levels: Longitudinal apolipoprotein E genotype effects
-
(1994)
Genet. Epidemiol.
, vol.11
, pp. 375-384
-
-
Jarvik, G.P.1
Justin, M.A.2
Fabsitz, R.R.3
Auwerx, J.4
Reed, T.5
Christian, J.C.6
Deeb, S.7
-
18
-
-
0029072551
-
Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: A case-control study
-
(1995)
Neurology
, vol.45
, pp. 1092-1096
-
-
Jarvik, G.P.1
Wijsman, E.M.2
Kukull, W.A.3
Schellenberg, G.D.4
Yu, C.5
Larson, E.B.6
-
21
-
-
0033569653
-
Membrane-anchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein
-
(1999)
Biochem. J.
, vol.343
, pp. 371-375
-
-
Koike, H.1
Tomioka, S.2
Sorimachi, H.3
Saido, T.C.4
Maruyama, K.5
Okuyama, A.6
Fujisawa-Sehara, A.7
Ohno, S.8
Suzuki, K.9
Ishiura, S.10
-
24
-
-
0040510921
-
Development expression of wild type and mutant presenilin-1 in hippocampal neurons from transgenic mice: Evidence for novel species-specific properties of human presenilin-1
-
(1999)
Mol. Med.
, vol.5
, pp. 542-554
-
-
Levesque, L.1
Annaert, W.2
Craessarts, K.3
Mathews, P.M.4
Seeger, M.5
Nixon, R.A.6
Van Leuven, F.7
Gandy, S.8
Westaway, D.9
St. George-Hyslop, P.10
DeStrooper, B.11
Fraser, P.12
-
25
-
-
0033595556
-
ApoE genotype in relation to AD and cholesterol: A study of 2,326 Chinese adults
-
(1999)
Neurology
, vol.53
, pp. 962-966
-
-
Liu, H.C.1
Hong, C.J.2
Wang, S.J.3
Fuh, J.L.4
Wang, P.N.5
Shyu, H.Y.6
Teng, E.L.7
-
27
-
-
0030779677
-
Cellular actions of beta-amyloid precursor prorein and its soluble and fibrillogenic derivatives
-
(1997)
Physiol. Rev.
, vol.77
, pp. 1081-1132
-
-
Mattson, M.1
-
28
-
-
0032886415
-
Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes
-
(1999)
Neurobiol. Dis.
, vol.6
, pp. 231-244
-
-
McGowan, E.1
Sanders, S.2
Iwatsubo, T.3
Takeuchi, A.4
Saido, T.5
Zehr, C.6
Yu, X.7
Uljon, S.8
Wang, R.9
Mann, D.10
Dickson, D.11
Duff, K.12
-
32
-
-
0033178782
-
Caveolin-3 upregulation activates beta-secretase-mediated cleavage of the amyloid precursor protein in Alzheimer's disease
-
(1999)
J. Neurosci.
, vol.19
, pp. 6538-6548
-
-
Nishiyama, K.1
Trapp, B.D.2
Ikezu, T.3
Ransohoff, R.M.4
Tomita, T.5
Iwatsubo, T.6
Kanazawa, I.7
Hsiao, K.K.8
Lisanti, M.P.9
Okamoto, T.10
-
33
-
-
0031976318
-
Serum cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease
-
(1998)
Neuroepidemiology
, vol.17
, pp. 14-20
-
-
Notkola, I.L.1
Sulkava, R.2
Pekkanen, J.3
Erkinjuntti, T.4
Ehnholm, C.5
Kivinen, P.6
Tuomilehto, J.7
Nissinen, A.8
-
36
-
-
0033578719
-
Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26810-26814
-
-
Sambamurti, K.1
Sevlever, D.2
Koothan, T.3
Refolo, L.M.4
Pinnix, I.5
Gandhi, S.6
Onstead, L.7
Younkin, L.8
Prada, C.M.9
Yager, D.10
Ohyagi, Y.11
Eckman, C.B.12
Rosenberry, T.L.13
Younkin, S.G.14
-
39
-
-
9844226208
-
Coronary artery disease, hypertension, ApoE, and cholesterol: A link to Alzheimer's disease?
-
(1997)
Ann. N.Y. Acad. Sci.
, vol.826
, pp. 128-146
-
-
Sparks, D.L.1
-
42
-
-
15844425969
-
Endoproteolysis of presenllin 1 and accumulation of processed derivatives in vivo
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
Ratovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
Hardy, J.11
Levey, A.I.12
Gandy, S.E.13
Jenkins, N.A.14
Copeland, N.G.15
Price, D.L.16
Sisodia, S.S.17
-
43
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
48
-
-
0025989554
-
Modulation of membrane function by cholesterol
-
(1991)
Biochimie
, vol.73
, pp. 1303-1310
-
-
Yeagle, P.L.1
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