How cholesterol constrains glycolipid conformation for optimal recognition of Alzheimer's β amyloid peptide (Aβ1-40)

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Yahi, Nouara ^a   Aulas, Anaïs ^a,b   Fantini, Jacques ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; CERAMIDE; CHOLESTEROL; FATTY ACID; GLYCOSPHINGOLIPID; NONHYDROXYLATED FATTY ACID; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; GANGLIOSIDE GM1; GANGLIOSIDE GM3; GLYCOLIPID; PEPTIDE FRAGMENT; SODIUM CHLORIDE;

ARTICLE; CRYSTALLOGRAPHY; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; ALZHEIMER DISEASE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; HUMAN; LIPID BILAYER; METABOLISM; SURFACE PROPERTY; X RAY CRYSTALLOGRAPHY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CHOLESTEROL; CRYSTALLOGRAPHY, X-RAY; FATTY ACIDS; G(M1) GANGLIOSIDE; G(M3) GANGLIOSIDE; GLYCOLIPIDS; GLYCOSPHINGOLIPIDS; HUMANS; LIPID BILAYERS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PEPTIDE FRAGMENTS; PROTEIN BINDING; SODIUM CHLORIDE; SURFACE PROPERTIES;

EID: 77949360652     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009079     Document Type: Article

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