-
1
-
-
0036884979
-
Presentation of the Kober Medal to Joseph L. Goldstein and Michael S. Brown
-
Foster D.W., Wilson J.D. Presentation of the Kober Medal to Joseph L. Goldstein and Michael S. Brown. J. Clin. Invest. 110:2002;S5-S9.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 5-S9
-
-
Foster, D.W.1
Wilson, J.D.2
-
2
-
-
0015890890
-
Familial hypercholesterolemia: Identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity associated with overproduction of cholesterol
-
Goldstein J.L., Brown M.S. Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol. Proc. Natl. Acad. Sci. U. S. A. 70:1973;2804-2808.
-
(1973)
Proc. Natl. Acad. Sci. U. S. A.
, vol.70
, pp. 2804-2808
-
-
Goldstein, J.L.1
Brown, M.S.2
-
3
-
-
0016303130
-
Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemia
-
Goldstein J.L., et al. Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemia. Proc. Natl. Acad. Sci. U. S. A. 71:1974;4288-4292.
-
(1974)
Proc. Natl. Acad. Sci. U. S. A.
, vol.71
, pp. 4288-4292
-
-
Goldstein, J.L.1
-
4
-
-
0016241915
-
Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia
-
Goldstein J.L., Brown M.S. Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia. J. Biol. Chem. 249:1974;5153-5162.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 5153-5162
-
-
Goldstein, J.L.1
Brown, M.S.2
-
5
-
-
0017334127
-
Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts
-
Anderson R.G., et al. Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts. Cell. 10:1977;351-364.
-
(1977)
Cell
, vol.10
, pp. 351-364
-
-
Anderson, R.G.1
-
6
-
-
0000636835
-
Yolk protein uptake in the oocyte of the mosquito Aedes aegypti L
-
Roth T.F., Porter K.R. Yolk protein uptake in the oocyte of the mosquito Aedes aegypti L. J. Cell Biol. 20:1964;313-332.
-
(1964)
J. Cell Biol.
, vol.20
, pp. 313-332
-
-
Roth, T.F.1
Porter, K.R.2
-
7
-
-
0003150825
-
Surface specializations of absorbing cells
-
Fawcett D.W. Surface specializations of absorbing cells. J. Histochem. Cytochem. 13:1965;75-91.
-
(1965)
J. Histochem. Cytochem.
, vol.13
, pp. 75-91
-
-
Fawcett, D.W.1
-
8
-
-
0006496113
-
Clathrin: A unique protein associated with intracellular transfer of membrane by coated vesicles
-
Pearse B.M. Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles. Proc. Natl. Acad. Sci. U. S. A. 73:1976;1255-1259.
-
(1976)
Proc. Natl. Acad. Sci. U. S. A.
, vol.73
, pp. 1255-1259
-
-
Pearse, B.M.1
-
9
-
-
0017732631
-
A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts
-
Anderson R.G., et al. A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts. Nature. 270:1977;695-699.
-
(1977)
Nature
, vol.270
, pp. 695-699
-
-
Anderson, R.G.1
-
10
-
-
0022456630
-
The J.D. mutation in familial hypercholesterolemia: Amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors
-
Davis C.G., et al. The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors. Cell. 45:1986;15-24.
-
(1986)
Cell
, vol.45
, pp. 15-24
-
-
Davis, C.G.1
-
12
-
-
0025287684
-
Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice
-
Pathak R.K., et al. Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice. J. Cell Biol. 111:1990;347-359.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 347-359
-
-
Pathak, R.K.1
-
13
-
-
0035906961
-
Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein
-
Garcia C.K., et al. Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein. Science. 292:2001;1394-1398.
-
(2001)
Science
, vol.292
, pp. 1394-1398
-
-
Garcia, C.K.1
-
14
-
-
0027490174
-
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
-
Yokoyama C., et al. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell. 75:1993;187-197.
-
(1993)
Cell
, vol.75
, pp. 187-197
-
-
Yokoyama, C.1
-
15
-
-
0025194466
-
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides
-
Reiss Y., et al. Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides. Cell. 62:1990;81-88.
-
(1990)
Cell
, vol.62
, pp. 81-88
-
-
Reiss, Y.1
-
16
-
-
0025871919
-
CDNA cloning and expression of the peptide-binding beta subunit of rat p21ras farnesyltransferase, the counterpart of yeast DPR1/RAM1
-
Chen W.J., et al. cDNA cloning and expression of the peptide-binding beta subunit of rat p21ras farnesyltransferase, the counterpart of yeast DPR1/RAM1. Cell. 66:1991;327-334.
-
(1991)
Cell
, vol.66
, pp. 327-334
-
-
Chen, W.J.1
-
17
-
-
0028063058
-
Benzodiazepine peptidomimetic BZA-5B interrupts the MAP kinase activation pathway in H-Ras-transformed Rat-1 cells, but not in untransformed cells
-
James G.L., et al. Benzodiazepine peptidomimetic BZA-5B interrupts the MAP kinase activation pathway in H-Ras-transformed Rat-1 cells, but not in untransformed cells. J. Biol. Chem. 269:1994;27705-27714.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27705-27714
-
-
James, G.L.1
-
18
-
-
0021204120
-
Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins
-
Schmidt R.A., et al. Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins. J. Biol. Chem. 259:1984;10175-10180.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 10175-10180
-
-
Schmidt, R.A.1
-
19
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown M.S., Goldstein J.L. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 89:1997;331-340.
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
20
-
-
0034681260
-
Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
-
Brown M.S., et al. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell. 100:2000;391-398.
-
(2000)
Cell
, vol.100
, pp. 391-398
-
-
Brown, M.S.1
-
21
-
-
0037082099
-
Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis
-
Goldstein J.L., et al. Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis. Arch. Biochem. Biophys. 397:2002;139-148.
-
(2002)
Arch. Biochem. Biophys.
, vol.397
, pp. 139-148
-
-
Goldstein, J.L.1
-
22
-
-
0033613147
-
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
-
Brown M.S., Goldstein J.L. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc. Natl. Acad. Sci. U. S. A. 96:1999;11041-11048.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11041-11048
-
-
Brown, M.S.1
Goldstein, J.L.2
-
23
-
-
0034604350
-
Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes
-
Nohturfft A., et al. Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes. Cell. 102:2000;315-323.
-
(2000)
Cell
, vol.102
, pp. 315-323
-
-
Nohturfft, A.1
-
24
-
-
0026559095
-
Caveolin, a protein component of caveolae membrane coats
-
Rothberg K.G., et al. Caveolin, a protein component of caveolae membrane coats. Cell. 68:1992;673-682.
-
(1992)
Cell
, vol.68
, pp. 673-682
-
-
Rothberg, K.G.1
-
25
-
-
0025695634
-
Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate
-
Rothberg K.G., et al. Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate. J. Cell Biol. 111:1990;2931-2938.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 2931-2938
-
-
Rothberg, K.G.1
-
26
-
-
0036671360
-
Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism
-
Brown A.J., et al. Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism. Mol. Cell. 10:2002;237-245.
-
(2002)
Mol. Cell
, vol.10
, pp. 237-245
-
-
Brown, A.J.1
-
27
-
-
0034703033
-
Overexpression of membrane domain of SCAP prevents sterols from inhibiting SCAP.SREBP exit from endoplasmic reticulum
-
Yang T., et al. Overexpression of membrane domain of SCAP prevents sterols from inhibiting SCAP.SREBP exit from endoplasmic reticulum. J. Biol. Chem. 275:2000;29881-29886.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29881-29886
-
-
Yang, T.1
-
28
-
-
0037162719
-
Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
-
Yang T., et al. Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell. 110:2002;489-500.
-
(2002)
Cell
, vol.110
, pp. 489-500
-
-
Yang, T.1
-
29
-
-
0037245750
-
Accelerated degradation of HMG-CoA reductase mediated by binding of insig-1 to its sterol-sensing domain
-
Sever N., et al. Accelerated degradation of HMG-CoA reductase mediated by binding of insig-1 to its sterol-sensing domain. Mol. Cell. 11:2003;25-33.
-
(2003)
Mol. Cell
, vol.11
, pp. 25-33
-
-
Sever, N.1
-
30
-
-
0017239547
-
Receptor-mediated control of cholesterol metabolism
-
Brown M.S., Goldstein J.L. Receptor-mediated control of cholesterol metabolism. Science. 191:1976;150-154.
-
(1976)
Science
, vol.191
, pp. 150-154
-
-
Brown, M.S.1
Goldstein, J.L.2
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