Modulation of ABCA1 by an LXR agonist reduces beta-amyloid levels and improves outcome after traumatic brain injury

Journal of Neurotrauma

Volumn 28, Issue 2, 2011, Pages 225-236

  Loane, David J ^b   Washington, Patricia M ^a   Vardanian, Lilit ^a   Pocivavsek, Ana ^a   Hoe, Hyang Sook ^a   Duff, Karen E ^c   Cernak, Ibolja ^d   Rebeck, G William ^a   Faden, Alan I ^b   Burns, Mark P ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c NewYork Presbyterian Hospital   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

A clearance; amyloid precursor protein processing; beta amyloid; liver X receptor; traumatic brain injury

Indexed keywords

ABC TRANSPORTER A1; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN SIZE; CONTROLLED STUDY; CONVALESCENCE; INFLAMMATION; MOTOR COORDINATION; MOUSE; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN PROCESSING; TRAUMATIC BRAIN INJURY;

AMYLOID BETA-PEPTIDES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BRAIN INJURIES; DISEASE MODELS, ANIMAL; HYDROCARBONS, FLUORINATED; MICE; MICE, INBRED C57BL; ORPHAN NUCLEAR RECEPTORS; RECOVERY OF FUNCTION; SULFONAMIDES; TIME FACTORS; TREATMENT OUTCOME;

EID: 79951690872     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2010.1595     Document Type: Article

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