-
1
-
-
0036126850
-
Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people
-
Rockwood K., Kirkland S., Hogan D.B., MacKnight C., Merry H., Verreault R., et al. Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people. Arch Neurol 59 2 (2002) 223-227
-
(2002)
Arch Neurol
, vol.59
, Issue.2
, pp. 223-227
-
-
Rockwood, K.1
Kirkland, S.2
Hogan, D.B.3
MacKnight, C.4
Merry, H.5
Verreault, R.6
-
2
-
-
0942278990
-
Association between statin use and Alzheimer's disease
-
Zamrini E., McGwin G., and Roseman J.M. Association between statin use and Alzheimer's disease. Neuroepidemiology 23 1-2 (2004) 94-98
-
(2004)
Neuroepidemiology
, vol.23
, Issue.1-2
, pp. 94-98
-
-
Zamrini, E.1
McGwin, G.2
Roseman, J.M.3
-
3
-
-
0029888944
-
Intraneuronal β-amyloid immunoreactivity in the CNS
-
Sparks D.L. Intraneuronal β-amyloid immunoreactivity in the CNS. Neurobiol Aging 17 (1996) 291-299
-
(1996)
Neurobiol Aging
, vol.17
, pp. 291-299
-
-
Sparks, D.L.1
-
4
-
-
0000059281
-
Diversification of gamma-secretase activity versus beta-secretase inhibition by cholesterol depletion
-
Bergmann C.H. Diversification of gamma-secretase activity versus beta-secretase inhibition by cholesterol depletion. Neurobiol Aging 21 (2000) 278
-
(2000)
Neurobiol Aging
, vol.21
, pp. 278
-
-
Bergmann, C.H.1
-
5
-
-
0037817311
-
Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation
-
Hu W., Gray N.W., and Brimijoin S. Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation. J Neurochem 86 (2003) 470-478
-
(2003)
J Neurochem
, vol.86
, pp. 470-478
-
-
Hu, W.1
Gray, N.W.2
Brimijoin, S.3
-
6
-
-
33845261493
-
A rapid mathod of total lipid extraction and purification
-
Bligh E.G., and Dyer W.J. A rapid mathod of total lipid extraction and purification. Can J Biochem Physiol 37 (1959) 911-917
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
7
-
-
0029888309
-
In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incoporated
-
Diraison F., Pachiaudi C., and Beyot M. In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incoporated. Metabolism 45 7 (1996) 817-821
-
(1996)
Metabolism
, vol.45
, Issue.7
, pp. 817-821
-
-
Diraison, F.1
Pachiaudi, C.2
Beyot, M.3
-
10
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ 1-42/1-40 ratio in vitro and in vivo
-
Borchelt D.R., Thinakaran G., Eckman C.B., Lee M.K., Davenport F., Ratovitsky T., et al. Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ 1-42/1-40 ratio in vitro and in vivo. Neuron 17 (1996) 1005-1013
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
-
11
-
-
3042640736
-
High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs
-
Lutjohann D., Stroick M., Bertsch T., Kuhl S., Lindenthal B., Thelen K., et al. High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs. Steroids 69 6 (2004) 431-438
-
(2004)
Steroids
, vol.69
, Issue.6
, pp. 431-438
-
-
Lutjohann, D.1
Stroick, M.2
Bertsch, T.3
Kuhl, S.4
Lindenthal, B.5
Thelen, K.6
-
12
-
-
19944432452
-
Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex
-
Johnson-Anuna L.N., Eckert G.P., Keller J.H., Igbavboa U., Franke C., Fechner T., et al. Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex. J Pharm Exp Ther 312 (2005) 786-793
-
(2005)
J Pharm Exp Ther
, vol.312
, pp. 786-793
-
-
Johnson-Anuna, L.N.1
Eckert, G.P.2
Keller, J.H.3
Igbavboa, U.4
Franke, C.5
Fechner, T.6
-
13
-
-
0036672689
-
Statin therapy for Alzheimer's disease. Will it work?
-
Petanceska S.S., DeRosa S., Olm V., Diaz N., Sharma A., Thomas-Bryant T., et al. Statin therapy for Alzheimer's disease. Will it work?. J Mol Sci 16 (2002) 155-161
-
(2002)
J Mol Sci
, vol.16
, pp. 155-161
-
-
Petanceska, S.S.1
DeRosa, S.2
Olm, V.3
Diaz, N.4
Sharma, A.5
Thomas-Bryant, T.6
-
14
-
-
33644781781
-
Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not pravastatin
-
Thelen K.M., Rentsch K.M., Gutteck U., Heverin M., Olin M., Andersson U., et al. Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not pravastatin. J Pharmacol Exp Ther 316 3 (2006) 1146-1152
-
(2006)
J Pharmacol Exp Ther
, vol.316
, Issue.3
, pp. 1146-1152
-
-
Thelen, K.M.1
Rentsch, K.M.2
Gutteck, U.3
Heverin, M.4
Olin, M.5
Andersson, U.6
-
15
-
-
0032805692
-
New insights into the pharmacodynamic and pharmacokinetic properties of statins
-
Corsini A., Bellosta S., Baetta R., Fumagalli R., Paoletti R., and Bernini F. New insights into the pharmacodynamic and pharmacokinetic properties of statins. Pharmacol Ther 84 (1999) 413-428
-
(1999)
Pharmacol Ther
, vol.84
, pp. 413-428
-
-
Corsini, A.1
Bellosta, S.2
Baetta, R.3
Fumagalli, R.4
Paoletti, R.5
Bernini, F.6
-
16
-
-
33846439745
-
Bcl-2 upregulation and neuroprotection in guinea pig brain following chronic simvastatin treatment
-
Franke C., Noldner M., Abdel-Kader R., Johnson-Anuna L.N., Wood W.G., Muller W.E., et al. Bcl-2 upregulation and neuroprotection in guinea pig brain following chronic simvastatin treatment. Neurobiol Dis 25 (2007) 438-445
-
(2007)
Neurobiol Dis
, vol.25
, pp. 438-445
-
-
Franke, C.1
Noldner, M.2
Abdel-Kader, R.3
Johnson-Anuna, L.N.4
Wood, W.G.5
Muller, W.E.6
-
17
-
-
0028281788
-
In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors
-
Saheki A., Terasaki T., Tamai I., and Tsuji A. In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. Pharm Res 11 2 (1994 Feb) 305-311
-
(1994)
Pharm Res
, vol.11
, Issue.2
, pp. 305-311
-
-
Saheki, A.1
Terasaki, T.2
Tamai, I.3
Tsuji, A.4
-
18
-
-
0033549840
-
Drug treatment of lipid disorders
-
Knopp R.H. Drug treatment of lipid disorders. N Engl J Med 341 (1999) 498-511
-
(1999)
N Engl J Med
, vol.341
, pp. 498-511
-
-
Knopp, R.H.1
-
19
-
-
0036964776
-
HMG-CoA reductase inhibitors (statins) in the treatment of Alzheimer's disease and why it would be ill-advise to use one that crosses the blood-brain barrier
-
Sparks D.L., Connor D.J., Browne P.J., Lopez J.E., and Sabbagh M.N. HMG-CoA reductase inhibitors (statins) in the treatment of Alzheimer's disease and why it would be ill-advise to use one that crosses the blood-brain barrier. J Nutr Health Aging 6 5 (2002) 324-331
-
(2002)
J Nutr Health Aging
, vol.6
, Issue.5
, pp. 324-331
-
-
Sparks, D.L.1
Connor, D.J.2
Browne, P.J.3
Lopez, J.E.4
Sabbagh, M.N.5
-
20
-
-
34548530600
-
Effects of long-term administration of HMG-CoA reductase inhibitor, atorvastatin, on stroke events and local cerebral blood flox in stroke-prone spontaneously hypertensive rats
-
Tanaka N., Katayama Y., Katsumata T., Otori T., and Nishiyama Y. Effects of long-term administration of HMG-CoA reductase inhibitor, atorvastatin, on stroke events and local cerebral blood flox in stroke-prone spontaneously hypertensive rats. Brain Res 169 (2007) 125-132
-
(2007)
Brain Res
, vol.169
, pp. 125-132
-
-
Tanaka, N.1
Katayama, Y.2
Katsumata, T.3
Otori, T.4
Nishiyama, Y.5
-
21
-
-
0027723663
-
Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the blood-brain barrier
-
Tsui A., Saheki A., Tamai I., and Terasaki T. Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the blood-brain barrier. J Pharmacol Exp Ther 267 3 (1993) 1085-1090
-
(1993)
J Pharmacol Exp Ther
, vol.267
, Issue.3
, pp. 1085-1090
-
-
Tsui, A.1
Saheki, A.2
Tamai, I.3
Terasaki, T.4
-
22
-
-
0034770421
-
Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia
-
Malhotra H.S., and Goa K.L. Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia. Drugs 61 12 (2001) 1835-1881
-
(2001)
Drugs
, vol.61
, Issue.12
, pp. 1835-1881
-
-
Malhotra, H.S.1
Goa, K.L.2
-
23
-
-
0034672439
-
Methodological issues in microdialysis sampling for pharmacokinetic studies
-
de Lange E.C.M., de Boer A.G., and Breimer D.D. Methodological issues in microdialysis sampling for pharmacokinetic studies. Adv Drug Deliv Rev 45 (2000) 125-148
-
(2000)
Adv Drug Deliv Rev
, vol.45
, pp. 125-148
-
-
de Lange, E.C.M.1
de Boer, A.G.2
Breimer, D.D.3
-
24
-
-
0032573572
-
Elevated low-density lipoprotein in Alzheimer's disease correlates with brain A-beta 1-42 levels
-
Kuo Y.M., Emmerling M.R., Bisgaier C.L., Essenburg A.D., Lampert H.C., Drumm D., et al. Elevated low-density lipoprotein in Alzheimer's disease correlates with brain A-beta 1-42 levels. BBRC 252 (1998) 711-715
-
(1998)
BBRC
, vol.252
, pp. 711-715
-
-
Kuo, Y.M.1
Emmerling, M.R.2
Bisgaier, C.L.3
Essenburg, A.D.4
Lampert, H.C.5
Drumm, D.6
-
25
-
-
4243873725
-
Correlation between serum cholesterol parameters and plasma amyloid beta protein
-
Arvanitakis Z., Lucas J.A., and Graff-Radford N.R. Correlation between serum cholesterol parameters and plasma amyloid beta protein. Neurobiol Aging 21 (2000) 96
-
(2000)
Neurobiol Aging
, vol.21
, pp. 96
-
-
Arvanitakis, Z.1
Lucas, J.A.2
Graff-Radford, N.R.3
-
26
-
-
0034990260
-
Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Abeta peptide
-
Buxbaum J.D., Geoghagen N.S., and Friedhoff L.T. Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Abeta peptide. J Alzheimers Dis 3 2 (2001) 221-229
-
(2001)
J Alzheimers Dis
, vol.3
, Issue.2
, pp. 221-229
-
-
Buxbaum, J.D.1
Geoghagen, N.S.2
Friedhoff, L.T.3
-
27
-
-
0037159224
-
Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide
-
Fassbender K., Stroick M., Bertsch T., Ragoschke A., Kuehl S., Walter S., et al. Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide. Neurology 59 (2002) 1257-1258
-
(2002)
Neurology
, vol.59
, pp. 1257-1258
-
-
Fassbender, K.1
Stroick, M.2
Bertsch, T.3
Ragoschke, A.4
Kuehl, S.5
Walter, S.6
-
28
-
-
12144290725
-
Plasma levels of beta-amyloid (1-40), beta-amyloid (1-42), and total beta-amyloid remain unaffected in adult patients with hypercholesterolemia after treatment with statins
-
Hoglund K., Wiklund O., Vanderstichele H., Eikenberg O., Vanmechelen E., and Blenow K. Plasma levels of beta-amyloid (1-40), beta-amyloid (1-42), and total beta-amyloid remain unaffected in adult patients with hypercholesterolemia after treatment with statins. Arch Neurol 61 3 (2004) 333-337
-
(2004)
Arch Neurol
, vol.61
, Issue.3
, pp. 333-337
-
-
Hoglund, K.1
Wiklund, O.2
Vanderstichele, H.3
Eikenberg, O.4
Vanmechelen, E.5
Blenow, K.6
-
29
-
-
23744516018
-
Statin treatment and a disease-specific pattern of β-amyloid peptides in Alzheimer's disease
-
Hoglund K., Syversen S., Lewczuk P., Wallin A., Wiltfang J., and Blennow K. Statin treatment and a disease-specific pattern of β-amyloid peptides in Alzheimer's disease. Exp Brain Res 164 (2005) 205-214
-
(2005)
Exp Brain Res
, vol.164
, pp. 205-214
-
-
Hoglund, K.1
Syversen, S.2
Lewczuk, P.3
Wallin, A.4
Wiltfang, J.5
Blennow, K.6
-
30
-
-
0037262480
-
Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved amyloid precursor protein
-
Sjogren M., Gustafsson K., Syversen S., Olsson A., Edman A., Davidsson P., et al. Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved amyloid precursor protein. Dement Geriatr Cogn Disord 16 1 (2003) 25-30
-
(2003)
Dement Geriatr Cogn Disord
, vol.16
, Issue.1
, pp. 25-30
-
-
Sjogren, M.1
Gustafsson, K.2
Syversen, S.3
Olsson, A.4
Edman, A.5
Davidsson, P.6
-
31
-
-
41749094111
-
Differential effects of statins and alendronate on cholinesterases in serum and brain of rats
-
Cibickova L., Palicka V., Cibicek N., Cermakova E., Micuda S., Bartosova L., et al. Differential effects of statins and alendronate on cholinesterases in serum and brain of rats. Physiol Res 56 6 (2007) 765-770
-
(2007)
Physiol Res
, vol.56
, Issue.6
, pp. 765-770
-
-
Cibickova, L.1
Palicka, V.2
Cibicek, N.3
Cermakova, E.4
Micuda, S.5
Bartosova, L.6
-
32
-
-
3543104951
-
Cholesterol metabolism in the central nervous system during early development and in the mature animal
-
Dietschy J.M., and Turley S.D. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res 45 (2004) 1375-1397
-
(2004)
J Lipid Res
, vol.45
, pp. 1375-1397
-
-
Dietschy, J.M.1
Turley, S.D.2
-
33
-
-
0014143997
-
A comprehensive study of the postnatal changes in the concentration of the lipids of developing rat brain
-
Wells M.A., and Dittmer J.C. A comprehensive study of the postnatal changes in the concentration of the lipids of developing rat brain. Biochemistry 6 10 (1967) 3169-3175
-
(1967)
Biochemistry
, vol.6
, Issue.10
, pp. 3169-3175
-
-
Wells, M.A.1
Dittmer, J.C.2
-
34
-
-
0017087316
-
Cholesterol transfer between brain and plasma in the rat: a model for the turnover of cerebral cholesterol
-
Serougne C., Lefevre C., and Chevallier F. Cholesterol transfer between brain and plasma in the rat: a model for the turnover of cerebral cholesterol. Exp Neurol 51 (1976) 229-240
-
(1976)
Exp Neurol
, vol.51
, pp. 229-240
-
-
Serougne, C.1
Lefevre, C.2
Chevallier, F.3
-
35
-
-
0033925026
-
Diurnal and dietary-induced changes in cholesterol synthesis correlate with levels of mRNA ofr HMG-CoA reductase
-
Jurevics H., Hostettler J., Barrett C., Morell P., and Toews A.D. Diurnal and dietary-induced changes in cholesterol synthesis correlate with levels of mRNA ofr HMG-CoA reductase. J Lipid Res 41 (2000) 1048-1053
-
(2000)
J Lipid Res
, vol.41
, pp. 1048-1053
-
-
Jurevics, H.1
Hostettler, J.2
Barrett, C.3
Morell, P.4
Toews, A.D.5
-
36
-
-
0344011516
-
Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse
-
Guan G., Xie Ch., Dietschy J.M., and Turley S.D. Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse. Dev Brain Res 146 (2003) 87-98
-
(2003)
Dev Brain Res
, vol.146
, pp. 87-98
-
-
Guan, G.1
Xie, Ch.2
Dietschy, J.M.3
Turley, S.D.4
-
37
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
Refolo L.M., Pappolla M.A., Malester B., LaFrancois J., Bryant-Thomas T., Wang R., et al. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 7 (2000) 321-331
-
(2000)
Neurobiol Dis
, vol.7
, pp. 321-331
-
-
Refolo, L.M.1
Pappolla, M.A.2
Malester, B.3
LaFrancois, J.4
Bryant-Thomas, T.5
Wang, R.6
|