메뉴 건너뛰기




Volumn 43, Issue , 2007, Pages 229-280

Cytochrome P450: Another Player in the Myocardial Infarction Game?

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

EID: 33845630317     PISSN: 00652423     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2423(06)43008-0     Document Type: Review
Times cited : (1)

References (472)
  • 1
    • 0035802683 scopus 로고    scopus 로고
    • Acute coronary syndrome without ST elevation: Implementation of new guidelines
    • Hamm C., Bertrand M., and Braunwald E. Acute coronary syndrome without ST elevation: Implementation of new guidelines. Lancet 358 (2001) 1533-1538
    • (2001) Lancet , vol.358 , pp. 1533-1538
    • Hamm, C.1    Bertrand, M.2    Braunwald, E.3
  • 3
    • 0037785185 scopus 로고    scopus 로고
    • Cardiovascular disease
    • Nabel E. Cardiovascular disease. N Engl J Med 349 (2003) 60-72
    • (2003) N Engl J Med , vol.349 , pp. 60-72
    • Nabel, E.1
  • 4
    • 0036486872 scopus 로고    scopus 로고
    • Evolution of all-cause mortality rates in the United States of America, anno 1900-1999
    • Kesteloot H. Evolution of all-cause mortality rates in the United States of America, anno 1900-1999. Acta Cardiol 57 (2002) 1-4
    • (2002) Acta Cardiol , vol.57 , pp. 1-4
    • Kesteloot, H.1
  • 5
    • 0030807192 scopus 로고    scopus 로고
    • The burden of cardiovascular diseases mortality in Europe. Task Force of the European Society of Cardiology on Cardiovascular Mortality and Morbidity Statistics in Europe
    • Sans S., Kesteloot H., and Kromhout D. The burden of cardiovascular diseases mortality in Europe. Task Force of the European Society of Cardiology on Cardiovascular Mortality and Morbidity Statistics in Europe. Eur Heart J 18 (1997) 1231-1248
    • (1997) Eur Heart J , vol.18 , pp. 1231-1248
    • Sans, S.1    Kesteloot, H.2    Kromhout, D.3
  • 6
    • 0033535812 scopus 로고    scopus 로고
    • Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease
    • Tunstall-Pedoe H., Kuulasmaa K., Mahonen M., Tolonen H., Ruokokoski E., and Amouyel P. Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease. Lancet 353 (1999) 1547-1557
    • (1999) Lancet , vol.353 , pp. 1547-1557
    • Tunstall-Pedoe, H.1    Kuulasmaa, K.2    Mahonen, M.3    Tolonen, H.4    Ruokokoski, E.5    Amouyel, P.6
  • 7
    • 0034716472 scopus 로고    scopus 로고
    • Estimation of contribution of changes in coronary care to improving survival, event rates, and coronary heart disease mortality across the WHO MONICA Project populations
    • Tunstall-Pedoe H., Vanuzzo D., Hobbs M., Mahonen M., Cepaitis Z., Kuulasmaa K., et al. Estimation of contribution of changes in coronary care to improving survival, event rates, and coronary heart disease mortality across the WHO MONICA Project populations. Lancet 355 (2000) 688-700
    • (2000) Lancet , vol.355 , pp. 688-700
    • Tunstall-Pedoe, H.1    Vanuzzo, D.2    Hobbs, M.3    Mahonen, M.4    Cepaitis, Z.5    Kuulasmaa, K.6
  • 8
    • 0032989350 scopus 로고    scopus 로고
    • Cardiovascular disease in the Netherlands, 1975 to 1995: Decline in mortality, but increasing numbers of patients with chronic conditions
    • Reitsma J., Dalstra J., Bonsel G., van der Meulen J., Koster R., Gunning-Schepers L., et al. Cardiovascular disease in the Netherlands, 1975 to 1995: Decline in mortality, but increasing numbers of patients with chronic conditions. Heart 82 (1999) 52-56
    • (1999) Heart , vol.82 , pp. 52-56
    • Reitsma, J.1    Dalstra, J.2    Bonsel, G.3    van der Meulen, J.4    Koster, R.5    Gunning-Schepers, L.6
  • 9
    • 0026541706 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes (2)
    • Fuster V., Badimon L., Badimon J., and Chesebro J. The pathogenesis of coronary artery disease and the acute coronary syndromes (2). N Engl J Med 326 (1992) 310-318
    • (1992) N Engl J Med , vol.326 , pp. 310-318
    • Fuster, V.1    Badimon, L.2    Badimon, J.3    Chesebro, J.4
  • 10
    • 0027125530 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes (1)
    • Fuster V., Badimon L., Badimon J., and Chesebro J. The pathogenesis of coronary artery disease and the acute coronary syndromes (1). N Engl J Med 326 (1992) 242-250
    • (1992) N Engl J Med , vol.326 , pp. 242-250
    • Fuster, V.1    Badimon, L.2    Badimon, J.3    Chesebro, J.4
  • 11
    • 0035814837 scopus 로고    scopus 로고
    • Thrombus formation on atherosclerotic plaques: Pathogenesis and clinical consequences
    • Rauch U., Osende J., Fuster V., Badimon J., Fayad Z., and Chesebro J. Thrombus formation on atherosclerotic plaques: Pathogenesis and clinical consequences. Ann Intern Med 134 (2001) 224-238
    • (2001) Ann Intern Med , vol.134 , pp. 224-238
    • Rauch, U.1    Osende, J.2    Fuster, V.3    Badimon, J.4    Fayad, Z.5    Chesebro, J.6
  • 12
    • 0000938978 scopus 로고
    • Strategies of prevention: The individual and the population
    • Marmot M., and Elliot P. (Eds), Oxford University Press, Oxford
    • Rose G. Strategies of prevention: The individual and the population. In: Marmot M., and Elliot P. (Eds). Coronary Heart Disease Epidemiology: From Aetiology to Public Health (1992), Oxford University Press, Oxford 311-324
    • (1992) Coronary Heart Disease Epidemiology: From Aetiology to Public Health , pp. 311-324
    • Rose, G.1
  • 13
    • 0031728287 scopus 로고    scopus 로고
    • Prevention of coronary heart disease in clinical practice: Recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention
    • Wood D., De Backer G., Faergeman O., Graham I., Mancia G., and Pyorala K. Prevention of coronary heart disease in clinical practice: Recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention. Atherosclerosis 140 (1998) 199-270
    • (1998) Atherosclerosis , vol.140 , pp. 199-270
    • Wood, D.1    De Backer, G.2    Faergeman, O.3    Graham, I.4    Mancia, G.5    Pyorala, K.6
  • 14
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
    • Yusuf S., Hawken S., Ounpuu S., Dans T., Avezum A., Lanas F., et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet 364 (2004) 937-952
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3    Dans, T.4    Avezum, A.5    Lanas, F.6
  • 15
    • 33644878800 scopus 로고    scopus 로고
    • New and old cardiovascular risk factors: C-reactive protein, homocysteine, cysteine and von Willebrand factor increase risk, especially in smokers
    • O'Callaghan P., Fitzgerald A., Fogarty J., Gaffney P., Hanbidge M., Boran G., et al. New and old cardiovascular risk factors: C-reactive protein, homocysteine, cysteine and von Willebrand factor increase risk, especially in smokers. Eur J Cardiovasc Prev Rehabil 12 (2005) 542-547
    • (2005) Eur J Cardiovasc Prev Rehabil , vol.12 , pp. 542-547
    • O'Callaghan, P.1    Fitzgerald, A.2    Fogarty, J.3    Gaffney, P.4    Hanbidge, M.5    Boran, G.6
  • 16
    • 0036153485 scopus 로고    scopus 로고
    • Inflammatory gene polymorphisms and ischaemic heart disease: Review of population association studies
    • Andreotti F., Porto I., Crea F., and Maseri A. Inflammatory gene polymorphisms and ischaemic heart disease: Review of population association studies. Heart 87 (2002) 107-112
    • (2002) Heart , vol.87 , pp. 107-112
    • Andreotti, F.1    Porto, I.2    Crea, F.3    Maseri, A.4
  • 17
    • 0032562263 scopus 로고    scopus 로고
    • Increasing burden of cardiovascular disease: Current knowledge and future directions for research on risk factors
    • Hennekens C. Increasing burden of cardiovascular disease: Current knowledge and future directions for research on risk factors. Circulation 97 (1998) 1095-1102
    • (1998) Circulation , vol.97 , pp. 1095-1102
    • Hennekens, C.1
  • 18
    • 24344464401 scopus 로고    scopus 로고
    • Cytochrome P450 and arachidonic acid metabolites: Role in myocardial ischemia/reperfusion injury revisited
    • Gross G., Falck J., Gross E., Isbell M., Moore J., and Nithipatikom K. Cytochrome P450 and arachidonic acid metabolites: Role in myocardial ischemia/reperfusion injury revisited. Cardiovasc Res 68 (2005) 18-25
    • (2005) Cardiovasc Res , vol.68 , pp. 18-25
    • Gross, G.1    Falck, J.2    Gross, E.3    Isbell, M.4    Moore, J.5    Nithipatikom, K.6
  • 19
    • 20844452556 scopus 로고    scopus 로고
    • Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2
    • Spiecker M., Darius H., Hankeln T., Soufi M., Sattler A., Schaefer J., et al. Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation 110 (2004) 2132-2136
    • (2004) Circulation , vol.110 , pp. 2132-2136
    • Spiecker, M.1    Darius, H.2    Hankeln, T.3    Soufi, M.4    Sattler, A.5    Schaefer, J.6
  • 20
    • 9944254760 scopus 로고    scopus 로고
    • Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids
    • Spiecker M., and Liao J. Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids. Arch Biochem Biophys 433 (2005) 413-420
    • (2005) Arch Biochem Biophys , vol.433 , pp. 413-420
    • Spiecker, M.1    Liao, J.2
  • 21
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration
    • Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 324 (2002) 71-86
    • (2002) BMJ , vol.324 , pp. 71-86
  • 22
    • 0000093848 scopus 로고    scopus 로고
    • beta Blockade after myocardial infarction: Systematic review and meta regression analysis
    • Freemantle N., Cleland J., Young P., Mason J., and Harrison J. beta Blockade after myocardial infarction: Systematic review and meta regression analysis. BMJ 318 (1999) 1730-1737
    • (1999) BMJ , vol.318 , pp. 1730-1737
    • Freemantle, N.1    Cleland, J.2    Young, P.3    Mason, J.4    Harrison, J.5
  • 23
    • 18344407031 scopus 로고    scopus 로고
    • Clinical effects of early angiotensin-converting enzyme inhibitor treatment for acute myocardial infarction are similar in the presence and absence of aspirin: Systematic overview of individual data from 96,712 randomized patients. Angiotensin-converting Enzyme Inhibitor Myocardial Infarction Collaborative Group
    • Latini R., Tognoni G., Maggioni A., Baigent C., Braunwald E., Chen Z., et al. Clinical effects of early angiotensin-converting enzyme inhibitor treatment for acute myocardial infarction are similar in the presence and absence of aspirin: Systematic overview of individual data from 96,712 randomized patients. Angiotensin-converting Enzyme Inhibitor Myocardial Infarction Collaborative Group. J Am Coll Cardiol 35 (2000) 1801-1807
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1801-1807
    • Latini, R.1    Tognoni, G.2    Maggioni, A.3    Baigent, C.4    Braunwald, E.5    Chen, Z.6
  • 24
    • 0035804846 scopus 로고    scopus 로고
    • Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. The MIRACL study: A randomized controlled trial
    • Schwartz G., Olsson A., Ezekowitz M., Ganz P., Oliver M., Waters D., et al. Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. The MIRACL study: A randomized controlled trial. JAMA 285 (2001) 1711-1718
    • (2001) JAMA , vol.285 , pp. 1711-1718
    • Schwartz, G.1    Olsson, A.2    Ezekowitz, M.3    Ganz, P.4    Oliver, M.5    Waters, D.6
  • 25
    • 0001132313 scopus 로고    scopus 로고
    • Clinical reality of coronary prevention guidelines: A comparison of EUROASPIRE I and II in nine countries. EUROASPIRE I and II Group. European Action on Secondary Prevention by Intervention to Reduce Events
    • Clinical reality of coronary prevention guidelines: A comparison of EUROASPIRE I and II in nine countries. EUROASPIRE I and II Group. European Action on Secondary Prevention by Intervention to Reduce Events. Lancet 357 (2001) 995-1001
    • (2001) Lancet , vol.357 , pp. 995-1001
  • 26
    • 3242668707 scopus 로고    scopus 로고
    • Adherence to evidence-based therapies after discharge for acute coronary syndromes: An ongoing prospective, observational study
    • Eagle K., Kline-Rogers E., Goodman S., Gurfinkel E., Avezum A., Flather M., et al. Adherence to evidence-based therapies after discharge for acute coronary syndromes: An ongoing prospective, observational study. Am J Med 117 (2004) 73-81
    • (2004) Am J Med , vol.117 , pp. 73-81
    • Eagle, K.1    Kline-Rogers, E.2    Goodman, S.3    Gurfinkel, E.4    Avezum, A.5    Flather, M.6
  • 27
    • 0000877909 scopus 로고    scopus 로고
    • Prescription of cardiovascular drugs in outpatient care: A survey of outpatients in a German university hospital
    • Harder S., Thurmann P., Thierolf C., and Klepzig H. Prescription of cardiovascular drugs in outpatient care: A survey of outpatients in a German university hospital. Int J Clin Pharmacol Ther 36 (1998) 195-201
    • (1998) Int J Clin Pharmacol Ther , vol.36 , pp. 195-201
    • Harder, S.1    Thurmann, P.2    Thierolf, C.3    Klepzig, H.4
  • 28
    • 0034650214 scopus 로고    scopus 로고
    • Compliance with and dosing of angiotensin-converting-enzyme inhibitors before and after hospitalization
    • Roe C., Motheral B., Teitelbaum F., and Rich M. Compliance with and dosing of angiotensin-converting-enzyme inhibitors before and after hospitalization. Am J Health Syst Pharm 57 (2000) 139-145
    • (2000) Am J Health Syst Pharm , vol.57 , pp. 139-145
    • Roe, C.1    Motheral, B.2    Teitelbaum, F.3    Rich, M.4
  • 29
    • 0026564816 scopus 로고
    • Cytochrome P450: Progress and predictions
    • Coon M., Ding X., Pernecky S., and Vaz A. Cytochrome P450: Progress and predictions. FASEB J 6 (1992) 669-673
    • (1992) FASEB J , vol.6 , pp. 669-673
    • Coon, M.1    Ding, X.2    Pernecky, S.3    Vaz, A.4
  • 30
    • 0345356534 scopus 로고    scopus 로고
    • Cytochrome P450: Major player in reperfusion injury
    • Gottlieb R. Cytochrome P450: Major player in reperfusion injury. Arch Biochem Biophys 420 (2003) 262-267
    • (2003) Arch Biochem Biophys , vol.420 , pp. 262-267
    • Gottlieb, R.1
  • 31
    • 0742321734 scopus 로고    scopus 로고
    • Human drug metabolising cytochrome P450 enzymes: Properties and polymorphisms
    • Ingelman-Sundberg M. Human drug metabolising cytochrome P450 enzymes: Properties and polymorphisms. Naunyn Schmiedebergs Arch Pharmacol 369 (2004) 89-104
    • (2004) Naunyn Schmiedebergs Arch Pharmacol , vol.369 , pp. 89-104
    • Ingelman-Sundberg, M.1
  • 32
    • 0035955607 scopus 로고    scopus 로고
    • Cytochrome p450 and vascular homeostasis
    • Fleming I. Cytochrome p450 and vascular homeostasis. Circ Res 89 (2001) 753-762
    • (2001) Circ Res , vol.89 , pp. 753-762
    • Fleming, I.1
  • 33
    • 0032952056 scopus 로고    scopus 로고
    • Endothelin-1 and CYP450 arachidonate metabolites interact to promote tissue injury in DOCA-salt hypertension
    • Oyekan A., McAward K., Conetta J., Rosenfeld L., and McGiff J. Endothelin-1 and CYP450 arachidonate metabolites interact to promote tissue injury in DOCA-salt hypertension. Am J Physiol 276 (1999) R766-R775
    • (1999) Am J Physiol , vol.276
    • Oyekan, A.1    McAward, K.2    Conetta, J.3    Rosenfeld, L.4    McGiff, J.5
  • 34
    • 0033009103 scopus 로고    scopus 로고
    • P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues
    • Scarborough P., Ma J., Qu W., and Zeldin D. P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues. Drug Metab Rev 31 (1999) 205-234
    • (1999) Drug Metab Rev , vol.31 , pp. 205-234
    • Scarborough, P.1    Ma, J.2    Qu, W.3    Zeldin, D.4
  • 35
    • 0035986058 scopus 로고    scopus 로고
    • CYP4A mRNA, protein, and product in rat lungs: Novel localization in vascular endothelium
    • Zhu D., Zhang C., Medhora M., and Jacobs E. CYP4A mRNA, protein, and product in rat lungs: Novel localization in vascular endothelium. J Appl Physiol 93 (2002) 330-337
    • (2002) J Appl Physiol , vol.93 , pp. 330-337
    • Zhu, D.1    Zhang, C.2    Medhora, M.3    Jacobs, E.4
  • 36
    • 0034681831 scopus 로고    scopus 로고
    • Gene expression in distinct regions of the heart
    • Thum T., and Borlak J. Gene expression in distinct regions of the heart. Lancet 355 (2000) 979-983
    • (2000) Lancet , vol.355 , pp. 979-983
    • Thum, T.1    Borlak, J.2
  • 37
    • 0033993749 scopus 로고    scopus 로고
    • Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase
    • Capdevila J., Falck J., and Harris R. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. J Lipid Res 41 (2000) 163-181
    • (2000) J Lipid Res , vol.41 , pp. 163-181
    • Capdevila, J.1    Falck, J.2    Harris, R.3
  • 38
    • 0034813048 scopus 로고    scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) inhibition of coronary development is preceded by a decrease in myocyte proliferation and an increase in cardiac apoptosis
    • Ivnitski I., Elmaoued R., and Walker M. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) inhibition of coronary development is preceded by a decrease in myocyte proliferation and an increase in cardiac apoptosis. Teratology 64 (2001) 201-212
    • (2001) Teratology , vol.64 , pp. 201-212
    • Ivnitski, I.1    Elmaoued, R.2    Walker, M.3
  • 40
    • 0030391813 scopus 로고    scopus 로고
    • Renal cytochrome P450-dependent eicosanoids
    • Carroll M., and McGiff J. Renal cytochrome P450-dependent eicosanoids. Adv Exp Med Biol 407 (1997) 255-260
    • (1997) Adv Exp Med Biol , vol.407 , pp. 255-260
    • Carroll, M.1    McGiff, J.2
  • 43
    • 0033758628 scopus 로고    scopus 로고
    • Renal and cardiovascular actions of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids
    • Roman R., Maier K., Sun C., Harder D., and Alonso-Galicia M. Renal and cardiovascular actions of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids. Clin Exp Pharmacol Physiol 27 (2000) 855-865
    • (2000) Clin Exp Pharmacol Physiol , vol.27 , pp. 855-865
    • Roman, R.1    Maier, K.2    Sun, C.3    Harder, D.4    Alonso-Galicia, M.5
  • 44
    • 0030063499 scopus 로고    scopus 로고
    • Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
    • Wu S., Moomaw C., Tomer K., Falck J., and Zeldin D. Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J Biol Chem 271 (1996) 3460-3468
    • (1996) J Biol Chem , vol.271 , pp. 3460-3468
    • Wu, S.1    Moomaw, C.2    Tomer, K.3    Falck, J.4    Zeldin, D.5
  • 45
    • 17844385047 scopus 로고    scopus 로고
    • Metabolism-based drug-drug interactions: What determines individual variability in cytochrome P450 induction?
    • Tang C., Lin J., and Lu A. Metabolism-based drug-drug interactions: What determines individual variability in cytochrome P450 induction?. Drug Metab Dispos 33 (2005) 603-613
    • (2005) Drug Metab Dispos , vol.33 , pp. 603-613
    • Tang, C.1    Lin, J.2    Lu, A.3
  • 46
    • 0032793249 scopus 로고    scopus 로고
    • Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
    • Ingelman-Sundberg M., Oscarson M., and McLellan R. Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment. Trends Pharmacol Sci 20 (1999) 342-349
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 342-349
    • Ingelman-Sundberg, M.1    Oscarson, M.2    McLellan, R.3
  • 47
    • 0031794361 scopus 로고    scopus 로고
    • Inhibition and induction of cytochrome P450 and the clinical implications
    • Lin J., and Lu A. Inhibition and induction of cytochrome P450 and the clinical implications. Clin Pharmacokinet 35 (1998) 361-390
    • (1998) Clin Pharmacokinet , vol.35 , pp. 361-390
    • Lin, J.1    Lu, A.2
  • 48
    • 0035032568 scopus 로고    scopus 로고
    • Interindividual variability in inhibition and induction of cytochrome P450 enzymes
    • Lin J., and Lu A. Interindividual variability in inhibition and induction of cytochrome P450 enzymes. Annu Rev Pharmacol Toxicol 41 (2001) 535-567
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 535-567
    • Lin, J.1    Lu, A.2
  • 49
    • 0030995879 scopus 로고    scopus 로고
    • Molecular mechanisms of genetic polymorphisms of drug metabolism
    • Meyer U., and Zanger U. Molecular mechanisms of genetic polymorphisms of drug metabolism. Annu Rev Pharmacol Toxicol 37 (1997) 269-296
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 269-296
    • Meyer, U.1    Zanger, U.2
  • 50
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T., Yamazaki H., Mimura M., Inui Y., and Guengerich F. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270 (1994) 414-423
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.5
  • 51
    • 0035479620 scopus 로고    scopus 로고
    • Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes
    • Ingelman-Sundberg M. Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes. Mutat Res 482 (2001) 11-19
    • (2001) Mutat Res , vol.482 , pp. 11-19
    • Ingelman-Sundberg, M.1
  • 52
    • 0034103544 scopus 로고    scopus 로고
    • Human aryl hydrocarbon receptor nuclear translocator gene (ARNT) D/N511 polymorphism
    • Cao H., and Hegele R. Human aryl hydrocarbon receptor nuclear translocator gene (ARNT) D/N511 polymorphism. J Hum Genet 45 (2000) 92-93
    • (2000) J Hum Genet , vol.45 , pp. 92-93
    • Cao, H.1    Hegele, R.2
  • 53
    • 0034975420 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 regulation in disease states
    • Cheng P., and Morgan E. Hepatic cytochrome P450 regulation in disease states. Curr Drug Metab 2 (2001) 165-183
    • (2001) Curr Drug Metab , vol.2 , pp. 165-183
    • Cheng, P.1    Morgan, E.2
  • 54
    • 0042352219 scopus 로고    scopus 로고
    • Induction of drug-metabolizing enzymes: A path to the discovery of multiple cytochromes P450
    • Conney A. Induction of drug-metabolizing enzymes: A path to the discovery of multiple cytochromes P450. Annu Rev Pharmacol Toxicol 43 (2003) 1-30
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 1-30
    • Conney, A.1
  • 55
    • 0034777488 scopus 로고    scopus 로고
    • Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4
    • Hustert E., Zibat A., Presecan-Siedel E., Eiselt R., Mueller R., Fuss C., et al. Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4. Drug Metab Dispos 29 (2001) 1454-1459
    • (2001) Drug Metab Dispos , vol.29 , pp. 1454-1459
    • Hustert, E.1    Zibat, A.2    Presecan-Siedel, E.3    Eiselt, R.4    Mueller, R.5    Fuss, C.6
  • 56
    • 0037672902 scopus 로고    scopus 로고
    • Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P450 1A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes
    • Lin P., Hu S., and Chang T. Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P450 1A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes. Toxicol Sci 71 (2003) 20-26
    • (2003) Toxicol Sci , vol.71 , pp. 20-26
    • Lin, P.1    Hu, S.2    Chang, T.3
  • 57
    • 0034054613 scopus 로고    scopus 로고
    • Variation in induced CYP1A1 levels: Relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms
    • Smart J., and Daly A. Variation in induced CYP1A1 levels: Relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms. Pharmacogenetics 10 (2000) 11-24
    • (2000) Pharmacogenetics , vol.10 , pp. 11-24
    • Smart, J.1    Daly, A.2
  • 58
    • 0034785945 scopus 로고    scopus 로고
    • The human pregnane X receptor: Genomic structure and identification and functional characterization of natural allelic variants
    • Zhang J., Kuehl P., Green E., Touchman J., Watkins P., Daly A., et al. The human pregnane X receptor: Genomic structure and identification and functional characterization of natural allelic variants. Pharmacogenetics 11 (2001) 555-572
    • (2001) Pharmacogenetics , vol.11 , pp. 555-572
    • Zhang, J.1    Kuehl, P.2    Green, E.3    Touchman, J.4    Watkins, P.5    Daly, A.6
  • 59
    • 0037421584 scopus 로고    scopus 로고
    • Inheritance and drug response
    • Weinshilboum R. Inheritance and drug response. N Engl J Med 348 (2003) 529-537
    • (2003) N Engl J Med , vol.348 , pp. 529-537
    • Weinshilboum, R.1
  • 60
    • 0017603250 scopus 로고
    • Regulation of drug metabolism in man by environmental chemicals and diet
    • Conney A., Pantuck E., Hsiao K., Kuntzman R., Alvares A., and Kappas A. Regulation of drug metabolism in man by environmental chemicals and diet. Fed Proc 36 (1977) 1647-1652
    • (1977) Fed Proc , vol.36 , pp. 1647-1652
    • Conney, A.1    Pantuck, E.2    Hsiao, K.3    Kuntzman, R.4    Alvares, A.5    Kappas, A.6
  • 61
    • 0344740559 scopus 로고    scopus 로고
    • Induction of drug metabolism: The role of nuclear receptors
    • Handschin C., and Meyer U. Induction of drug metabolism: The role of nuclear receptors. Pharmacol Rev 55 (2003) 649-673
    • (2003) Pharmacol Rev , vol.55 , pp. 649-673
    • Handschin, C.1    Meyer, U.2
  • 62
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford L. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3 (2002) 229-243
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.1
  • 63
    • 28444454036 scopus 로고    scopus 로고
    • Cytochrome P450 3A: Genetic polymorphisms and inter-ethnic differences
    • Krishna D., and Shekar M. Cytochrome P450 3A: Genetic polymorphisms and inter-ethnic differences. Methods Find Exp Clin Pharmacol 27 (2005) 559-567
    • (2005) Methods Find Exp Clin Pharmacol , vol.27 , pp. 559-567
    • Krishna, D.1    Shekar, M.2
  • 64
    • 0042357440 scopus 로고    scopus 로고
    • PM frequencies of major CYPs in Asians and Caucasians
    • Mizutani T. PM frequencies of major CYPs in Asians and Caucasians. Drug Metab Rev 35 (2003) 99-106
    • (2003) Drug Metab Rev , vol.35 , pp. 99-106
    • Mizutani, T.1
  • 65
    • 6344285930 scopus 로고    scopus 로고
    • Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population
    • Solus J., Arietta B., Harris J., Sexton D., Steward J., McMunn C., et al. Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population. Pharmacogenomics 5 (2004) 895-931
    • (2004) Pharmacogenomics , vol.5 , pp. 895-931
    • Solus, J.1    Arietta, B.2    Harris, J.3    Sexton, D.4    Steward, J.5    McMunn, C.6
  • 66
    • 0035028479 scopus 로고    scopus 로고
    • Molecular basis of ethnic differences in drug disposition and response
    • Xie H., Kim R., Wood A., and Stein C. Molecular basis of ethnic differences in drug disposition and response. Annu Rev Pharmacol Toxicol 41 (2001) 815-850
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 815-850
    • Xie, H.1    Kim, R.2    Wood, A.3    Stein, C.4
  • 67
    • 33644664657 scopus 로고    scopus 로고
    • Pharmacogenetics of drug-metabolizing enzymes: Implications for a safer and more effective drug therapy
    • Ingelman-Sundberg M., and Rodriguez-Antona C. Pharmacogenetics of drug-metabolizing enzymes: Implications for a safer and more effective drug therapy. Philos Trans R Soc Lond B Biol Sci 360 (2005) 1563-1570
    • (2005) Philos Trans R Soc Lond B Biol Sci , vol.360 , pp. 1563-1570
    • Ingelman-Sundberg, M.1    Rodriguez-Antona, C.2
  • 68
    • 0024807790 scopus 로고
    • Genetic polymorphisms of drug-metabolizing enzymes: Molecular mechanisms
    • Meyer U., Zanger U., Skoda R., and Grant D. Genetic polymorphisms of drug-metabolizing enzymes: Molecular mechanisms. Psychopharmacol Ser 7 (1989) 141-147
    • (1989) Psychopharmacol Ser , vol.7 , pp. 141-147
    • Meyer, U.1    Zanger, U.2    Skoda, R.3    Grant, D.4
  • 69
    • 85013917085 scopus 로고    scopus 로고
    • Genetic polymorphism of human cytochrome p450 involved in drug metabolism
    • Nagata K., and Yamazoe Y. Genetic polymorphism of human cytochrome p450 involved in drug metabolism. Drug Metab Pharmacokinet 17 (2002) 167-189
    • (2002) Drug Metab Pharmacokinet , vol.17 , pp. 167-189
    • Nagata, K.1    Yamazoe, Y.2
  • 72
    • 21244461430 scopus 로고    scopus 로고
    • Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach
    • Castell J., Donato M., and Gomez-Lechon M. Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach. Exp Toxicol Pathol 57 Suppl. 1 (2005) 189-204
    • (2005) Exp Toxicol Pathol , vol.57 , Issue.SUPPL. 1 , pp. 189-204
    • Castell, J.1    Donato, M.2    Gomez-Lechon, M.3
  • 73
    • 0035154274 scopus 로고    scopus 로고
    • Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: Implications for interindividual differences in nicotine metabolism
    • Oscarson M. Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: Implications for interindividual differences in nicotine metabolism. Drug Metab Dispos 29 (2001) 91-95
    • (2001) Drug Metab Dispos , vol.29 , pp. 91-95
    • Oscarson, M.1
  • 74
    • 0345707570 scopus 로고    scopus 로고
    • Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK
    • Wang H., Hao B., Zhou G., He F., Tan W., Miao X., et al. Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK. Cancer Res 63 (2003) 8057-8061
    • (2003) Cancer Res , vol.63 , pp. 8057-8061
    • Wang, H.1    Hao, B.2    Zhou, G.3    He, F.4    Tan, W.5    Miao, X.6
  • 75
    • 0032945691 scopus 로고    scopus 로고
    • A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans
    • Nunoya K., Yokoi T., Kamataki T., Kimura K., Kainuma T., Satoh K., et al. A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans. J Pharmacol Exp Ther 289 (1999) 437-442
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 437-442
    • Nunoya, K.1    Yokoi, T.2    Kamataki, T.3    Kimura, K.4    Kainuma, T.5    Satoh, K.6
  • 76
    • 0033067287 scopus 로고    scopus 로고
    • Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population
    • Oscarson M., McLellan R., Ingelman-Sundberg M., GullstÈn H., Raunio H., Pelkonen O., et al. Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population. FEBS Lett 448 (1999) 105-110
    • (1999) FEBS Lett , vol.448 , pp. 105-110
    • Oscarson, M.1    McLellan, R.2    Ingelman-Sundberg, M.3    GullstÈn, H.4    Raunio, H.5    Pelkonen, O.6
  • 77
    • 0033807421 scopus 로고    scopus 로고
    • Duplications and defects in the CYP2A6 gene: Identification, genotyping, and in vivo effects on smoking
    • Rao Y., Hoffmann E., Zia M., Bodin L., Zeman M., Sellers E., et al. Duplications and defects in the CYP2A6 gene: Identification, genotyping, and in vivo effects on smoking. Mol Pharmacol 58 (2000) 747-755
    • (2000) Mol Pharmacol , vol.58 , pp. 747-755
    • Rao, Y.1    Hoffmann, E.2    Zia, M.3    Bodin, L.4    Zeman, M.5    Sellers, E.6
  • 78
    • 0036389893 scopus 로고    scopus 로고
    • Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity
    • Oscarson M., McLellan R., Asp V., Ledesma M., Bernal Ruiz M., Sinues B., et al. Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity. Hum Mutat 20 (2002) 275-283
    • (2002) Hum Mutat , vol.20 , pp. 275-283
    • Oscarson, M.1    McLellan, R.2    Asp, V.3    Ledesma, M.4    Bernal Ruiz, M.5    Sinues, B.6
  • 79
    • 0033067287 scopus 로고    scopus 로고
    • Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population
    • Oscarson M., McLellan R., Gullsten H., Yue Q., Lang M., Bernal M., et al. Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population. FEBS Lett 448 (1999) 105-110
    • (1999) FEBS Lett , vol.448 , pp. 105-110
    • Oscarson, M.1    McLellan, R.2    Gullsten, H.3    Yue, Q.4    Lang, M.5    Bernal, M.6
  • 80
    • 0034816629 scopus 로고    scopus 로고
    • Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: Impairment of its promoter activity
    • Pitarque M., von Richter O., Oke B., Berkkan H., Oscarson M., and Ingelman-Sundberg M. Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: Impairment of its promoter activity. Biochem Biophys Res Commun 284 (2001) 455-460
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 455-460
    • Pitarque, M.1    von Richter, O.2    Oke, B.3    Berkkan, H.4    Oscarson, M.5    Ingelman-Sundberg, M.6
  • 82
    • 0033965729 scopus 로고    scopus 로고
    • Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans
    • Nakajima M., Yamagishi S., Yamamoto H., Yamamoto T., Kuroiwa Y., and Yokoi T. Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans. Clin Pharmacol Ther 67 (2000) 57-69
    • (2000) Clin Pharmacol Ther , vol.67 , pp. 57-69
    • Nakajima, M.1    Yamagishi, S.2    Yamamoto, H.3    Yamamoto, T.4    Kuroiwa, Y.5    Yokoi, T.6
  • 83
    • 0033659142 scopus 로고    scopus 로고
    • Structural characterization of a new variant of the CYP2A6 gene (CYP2A6*1B) apparently diagnosed as heterozygotes of CYP2A6*1A and CYP2A6*4C
    • Ariyoshi N., Takahashi Y., Miyamoto M., Umetsu Y., Daigo S., Tateishi T., et al. Structural characterization of a new variant of the CYP2A6 gene (CYP2A6*1B) apparently diagnosed as heterozygotes of CYP2A6*1A and CYP2A6*4C. Pharmacogenetics 10 (2000) 687-693
    • (2000) Pharmacogenetics , vol.10 , pp. 687-693
    • Ariyoshi, N.1    Takahashi, Y.2    Miyamoto, M.3    Umetsu, Y.4    Daigo, S.5    Tateishi, T.6
  • 84
    • 0032698297 scopus 로고    scopus 로고
    • Identification and characterisation of novel polymorphisms in the CYP2A locus: Implications for nicotine metabolism
    • Oscarson M., McLellan R., Ingelman-Sundberg M., GullstÈn H., Rautio A., Raunio H., et al. Identification and characterisation of novel polymorphisms in the CYP2A locus: Implications for nicotine metabolism. FEBS Lett 460 (1999) 321-327
    • (1999) FEBS Lett , vol.460 , pp. 321-327
    • Oscarson, M.1    McLellan, R.2    Ingelman-Sundberg, M.3    GullstÈn, H.4    Rautio, A.5    Raunio, H.6
  • 86
    • 0035138840 scopus 로고    scopus 로고
    • Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans
    • Nakajima M., Kwon J., Tanaka N., Zenta T., Yamamoto Y., Yamamoto H., et al. Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans. Clin Pharmacol Ther 69 (2001) 72-78
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 72-78
    • Nakajima, M.1    Kwon, J.2    Tanaka, N.3    Zenta, T.4    Yamamoto, Y.5    Yamamoto, H.6
  • 87
    • 0036260293 scopus 로고    scopus 로고
    • Variation in coumarin 7-hydroxylase activity associated with genetic polymorphism of cytochrome P450 2A6 and the body status of iron stores in adult Thai males and females
    • Ujjin P., Satarug S., Vanavanitkun Y., Daigo S., Ariyoshi N., Yamazaki H., et al. Variation in coumarin 7-hydroxylase activity associated with genetic polymorphism of cytochrome P450 2A6 and the body status of iron stores in adult Thai males and females. Pharmacogenetics 12 (2002) 241-249
    • (2002) Pharmacogenetics , vol.12 , pp. 241-249
    • Ujjin, P.1    Satarug, S.2    Vanavanitkun, Y.3    Daigo, S.4    Ariyoshi, N.5    Yamazaki, H.6
  • 88
    • 0036435654 scopus 로고    scopus 로고
    • Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
    • Yoshida R., Nakajima M., Watanabe Y., Kwon J., and Yokoi T. Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism. Br J Clin Pharmacol 54 (2002) 511-517
    • (2002) Br J Clin Pharmacol , vol.54 , pp. 511-517
    • Yoshida, R.1    Nakajima, M.2    Watanabe, Y.3    Kwon, J.4    Yokoi, T.5
  • 89
    • 29644437407 scopus 로고    scopus 로고
    • 3′-UTR polymorphism in the human CYP2A6 gene affects mRNA stability and enzyme expression
    • Wang J., Pitarque M., and Ingelman-Sundberg M. 3′-UTR polymorphism in the human CYP2A6 gene affects mRNA stability and enzyme expression. Biochem Biophys Res Commun 340 (2006) 491-497
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 491-497
    • Wang, J.1    Pitarque, M.2    Ingelman-Sundberg, M.3
  • 90
    • 23644456862 scopus 로고    scopus 로고
    • Association of CYP2A6*1B genetic variant with the amount of smoking in French adults from the Stanislas cohort
    • Gambier N., Batt A., Marie B., Pfister M., Siest G., and Visvikis-Siest S. Association of CYP2A6*1B genetic variant with the amount of smoking in French adults from the Stanislas cohort. Pharmacogenomics J 5 (2005) 271-275
    • (2005) Pharmacogenomics J , vol.5 , pp. 271-275
    • Gambier, N.1    Batt, A.2    Marie, B.3    Pfister, M.4    Siest, G.5    Visvikis-Siest, S.6
  • 92
    • 0033051029 scopus 로고    scopus 로고
    • Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles
    • Roy P., Yu L., Crespi C., and Waxman D. Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab Dispos 27 (1999) 655-666
    • (1999) Drug Metab Dispos , vol.27 , pp. 655-666
    • Roy, P.1    Yu, L.2    Crespi, C.3    Waxman, D.4
  • 93
    • 0035165506 scopus 로고    scopus 로고
    • Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes
    • Court M., Duan S., Hesse L., Venkatakrishnan K., and Greenblatt D. Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes. Anesthesiology 94 (2001) 110-119
    • (2001) Anesthesiology , vol.94 , pp. 110-119
    • Court, M.1    Duan, S.2    Hesse, L.3    Venkatakrishnan, K.4    Greenblatt, D.5
  • 94
    • 0033810079 scopus 로고    scopus 로고
    • Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity
    • Faucette S., Hawke R., Lecluyse E., Shord S., Yan B., Laethem R., et al. Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity. Drug Metab Dispos 28 (2000) 1222-1230
    • (2000) Drug Metab Dispos , vol.28 , pp. 1222-1230
    • Faucette, S.1    Hawke, R.2    Lecluyse, E.3    Shord, S.4    Yan, B.5    Laethem, R.6
  • 95
    • 0032853806 scopus 로고    scopus 로고
    • Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin
    • Svensson U., and Ashton M. Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin. Br J Clin Pharmacol 48 (1999) 528-535
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 528-535
    • Svensson, U.1    Ashton, M.2
  • 96
    • 0038002981 scopus 로고    scopus 로고
    • The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: Implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity
    • Ward B., Gorski J., Jones D., Hall S., Flockhart D., and Desta Z. The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: Implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. J Pharmacol Exp Ther 306 (2003) 287-300
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 287-300
    • Ward, B.1    Gorski, J.2    Jones, D.3    Hall, S.4    Flockhart, D.5    Desta, Z.6
  • 97
    • 0030739223 scopus 로고    scopus 로고
    • Human cytochrome P450 2B6: Interindividual hepatic expression, substrate specificity, and role in procarcinogen activation
    • Code E., Crespi C., Penman B., Gonzalez F., Chang T., and Waxman D. Human cytochrome P450 2B6: Interindividual hepatic expression, substrate specificity, and role in procarcinogen activation. Drug Metab Dispos 25 (1997) 985-993
    • (1997) Drug Metab Dispos , vol.25 , pp. 985-993
    • Code, E.1    Crespi, C.2    Penman, B.3    Gonzalez, F.4    Chang, T.5    Waxman, D.6
  • 99
    • 0142188754 scopus 로고    scopus 로고
    • Bupropion and 4-OH-bupropion pharmacokinetics in relation to genetic polymorphisms in CYP2B6
    • Kirchheiner J., Klein C., Meineke I., Sasse J., Zanger U., Murdter T., et al. Bupropion and 4-OH-bupropion pharmacokinetics in relation to genetic polymorphisms in CYP2B6. Pharmacogenetics 13 (2003) 619-626
    • (2003) Pharmacogenetics , vol.13 , pp. 619-626
    • Kirchheiner, J.1    Klein, C.2    Meineke, I.3    Sasse, J.4    Zanger, U.5    Murdter, T.6
  • 100
    • 0034948077 scopus 로고    scopus 로고
    • Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver
    • Lang T., Klein K., Fischer J., Nussler A., Neuhaus P., Hofmann U., et al. Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver. Pharmacogenetics 11 (2001) 399-415
    • (2001) Pharmacogenetics , vol.11 , pp. 399-415
    • Lang, T.1    Klein, K.2    Fischer, J.3    Nussler, A.4    Neuhaus, P.5    Hofmann, U.6
  • 101
    • 4644349582 scopus 로고    scopus 로고
    • Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: Demonstration of phenotypic null alleles
    • Lang T., Klein K., Richter T., Zibat A., Kerb R., Eichelbaum M., et al. Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: Demonstration of phenotypic null alleles. J Pharmacol Exp Ther 311 (2004) 34-43
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 34-43
    • Lang, T.1    Klein, K.2    Richter, T.3    Zibat, A.4    Kerb, R.5    Eichelbaum, M.6
  • 102
    • 17844375918 scopus 로고    scopus 로고
    • A natural CYP2B6 TATA box polymorphism (-82T→ C) leading to enhanced transcription and relocation of the transcriptional start site
    • Zukunft J., Lang T., Richter T., Hirsch-Ernst K., Nussler A., Klein K., et al. A natural CYP2B6 TATA box polymorphism (-82T→ C) leading to enhanced transcription and relocation of the transcriptional start site. Mol Pharmacol 67 (2005) 1772-1782
    • (2005) Mol Pharmacol , vol.67 , pp. 1772-1782
    • Zukunft, J.1    Lang, T.2    Richter, T.3    Hirsch-Ernst, K.4    Nussler, A.5    Klein, K.6
  • 103
    • 1942531624 scopus 로고    scopus 로고
    • Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes
    • Hesse L., He P., Krishnaswamy S., Hao Q., Hogan K., von Moltke L., et al. Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes. Pharmacogenetics 14 (2004) 225-238
    • (2004) Pharmacogenetics , vol.14 , pp. 225-238
    • Hesse, L.1    He, P.2    Krishnaswamy, S.3    Hao, Q.4    Hogan, K.5    von Moltke, L.6
  • 104
    • 2942551228 scopus 로고    scopus 로고
    • Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens
    • Tsuchiya K., Gatanaga H., Tachikawa N., Teruya K., Kikuchi Y., Yoshino M., et al. Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens. Biochem Biophys Res Commun 319 (2004) 1322-1326
    • (2004) Biochem Biophys Res Commun , vol.319 , pp. 1322-1326
    • Tsuchiya, K.1    Gatanaga, H.2    Tachikawa, N.3    Teruya, K.4    Kikuchi, Y.5    Yoshino, M.6
  • 106
    • 0034815451 scopus 로고    scopus 로고
    • A single nucleotide polymorphism of CYP2B6 found in Japanese enhances catalytic activity by autoactivation
    • Ariyoshi N., Miyazaki M., Toide K., Sawamura Y., and Kamataki T. A single nucleotide polymorphism of CYP2B6 found in Japanese enhances catalytic activity by autoactivation. Biochem Biophys Res Commun 281 (2001) 1256-1260
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 1256-1260
    • Ariyoshi, N.1    Miyazaki, M.2    Toide, K.3    Sawamura, Y.4    Kamataki, T.5
  • 107
    • 10744221053 scopus 로고    scopus 로고
    • Hepatic CYP2B6 expression: Gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression
    • Lamba V., Lamba J., Yasuda K., Strom S., Davila J., Hancock M., et al. Hepatic CYP2B6 expression: Gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression. J Pharmacol Exp Ther 307 (2003) 906-922
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 906-922
    • Lamba, V.1    Lamba, J.2    Yasuda, K.3    Strom, S.4    Davila, J.5    Hancock, M.6
  • 108
    • 0034874393 scopus 로고    scopus 로고
    • Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor
    • Goodwin B., Moore L., Stoltz C., McKee D., and Kliewer S. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor. Mol Pharmacol 60 (2001) 427-431
    • (2001) Mol Pharmacol , vol.60 , pp. 427-431
    • Goodwin, B.1    Moore, L.2    Stoltz, C.3    McKee, D.4    Kliewer, S.5
  • 109
    • 0037515661 scopus 로고    scopus 로고
    • A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression
    • Wang H., Faucette S., Sueyoshi T., Moore R., Ferguson S., Negishi M., et al. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression. J Biol Chem 278 (2003) 14146-14152
    • (2003) J Biol Chem , vol.278 , pp. 14146-14152
    • Wang, H.1    Faucette, S.2    Sueyoshi, T.3    Moore, R.4    Ferguson, S.5    Negishi, M.6
  • 110
    • 0033845886 scopus 로고    scopus 로고
    • Biochemical and molecular characteristics of the cytochrome P450 arachidonic acid monooxygenase
    • Capdevila J., and Falck J. Biochemical and molecular characteristics of the cytochrome P450 arachidonic acid monooxygenase. Prostaglandins Other Lipid Mediat 62 (2000) 271-292
    • (2000) Prostaglandins Other Lipid Mediat , vol.62 , pp. 271-292
    • Capdevila, J.1    Falck, J.2
  • 111
    • 27744554496 scopus 로고    scopus 로고
    • Cytochrome p450 2C inhibition reduces post-ischemic vascular dysfunction
    • Hunter A., Bai N., Laher I., and Granville D. Cytochrome p450 2C inhibition reduces post-ischemic vascular dysfunction. Vascul Pharmacol 43 (2005) 213-219
    • (2005) Vascul Pharmacol , vol.43 , pp. 213-219
    • Hunter, A.1    Bai, N.2    Laher, I.3    Granville, D.4
  • 112
    • 1342334719 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease
    • Fichtlscherer S., Dimmeler S., Breuer S., Zeiher A., Busse R., and Fleming I. Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease. Circulation 109 (2004) 178-183
    • (2004) Circulation , vol.109 , pp. 178-183
    • Fichtlscherer, S.1    Dimmeler, S.2    Breuer, S.3    Zeiher, A.4    Busse, R.5    Fleming, I.6
  • 114
    • 1842558550 scopus 로고    scopus 로고
    • Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction
    • Yasar U., Eliasson E., Lundgren S., Rane A., Bennet A., De Faire U., et al. Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction. Pharmacogenetics 13 (2003) 715-720
    • (2003) Pharmacogenetics , vol.13 , pp. 715-720
    • Yasar, U.1    Eliasson, E.2    Lundgren, S.3    Rane, A.4    Bennet, A.5    De Faire, U.6
  • 115
    • 11844304376 scopus 로고    scopus 로고
    • Clinical consequences of cytochrome P450 2C9 polymorphisms
    • Kirchheiner J., and Brockmoller J. Clinical consequences of cytochrome P450 2C9 polymorphisms. Clin Pharmacol Ther 77 (2005) 1-16
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 1-16
    • Kirchheiner, J.1    Brockmoller, J.2
  • 116
    • 0034791777 scopus 로고    scopus 로고
    • Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
    • Dai D., Zeldin D., Blaisdell J., Chanas B., Coulter S., Ghanayem B., et al. Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 11 (2001) 597-607
    • (2001) Pharmacogenetics , vol.11 , pp. 597-607
    • Dai, D.1    Zeldin, D.2    Blaisdell, J.3    Chanas, B.4    Coulter, S.5    Ghanayem, B.6
  • 117
    • 4143069198 scopus 로고    scopus 로고
    • CYP2C9 genotype as a predictor of drug disposition in humans
    • Lee C. CYP2C9 genotype as a predictor of drug disposition in humans. Methods Find Exp Clin Pharmacol 26 (2004) 463-472
    • (2004) Methods Find Exp Clin Pharmacol , vol.26 , pp. 463-472
    • Lee, C.1
  • 118
    • 0036263813 scopus 로고    scopus 로고
    • Cytochrome P450 2C9 polymorphisms: A comprehensive review of the in-vitro and human data
    • Lee C., Goldstein J., and Pieper J. Cytochrome P450 2C9 polymorphisms: A comprehensive review of the in-vitro and human data. Pharmacogenetics 12 (2002) 251-263
    • (2002) Pharmacogenetics , vol.12 , pp. 251-263
    • Lee, C.1    Goldstein, J.2    Pieper, J.3
  • 119
    • 11244284872 scopus 로고    scopus 로고
    • Upstream and coding region CYP2C9 polymorphisms: Correlation with warfarin dose and metabolism
    • King B., Khan T., Aithal G., Kamali F., and Daly A. Upstream and coding region CYP2C9 polymorphisms: Correlation with warfarin dose and metabolism. Pharmacogenetics 14 (2004) 813-822
    • (2004) Pharmacogenetics , vol.14 , pp. 813-822
    • King, B.1    Khan, T.2    Aithal, G.3    Kamali, F.4    Daly, A.5
  • 120
    • 0034892729 scopus 로고    scopus 로고
    • Genetic polymorphisms and functional characterization of the 5′-flanking region of the human CYP2C9 gene: In vitro and in vivo studies
    • Shintani M., Ieiri I., Inoue K., Mamiya K., Ninomiya H., Tashiro N., et al. Genetic polymorphisms and functional characterization of the 5′-flanking region of the human CYP2C9 gene: In vitro and in vivo studies. Clin Pharmacol Ther 70 (2001) 175-182
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 175-182
    • Shintani, M.1    Ieiri, I.2    Inoue, K.3    Mamiya, K.4    Ninomiya, H.5    Tashiro, N.6
  • 121
    • 0033608466 scopus 로고    scopus 로고
    • Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
    • Aithal G., Day C., Kesteven P., and Daly A. Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 353 (1999) 717-719
    • (1999) Lancet , vol.353 , pp. 717-719
    • Aithal, G.1    Day, C.2    Kesteven, P.3    Daly, A.4
  • 122
    • 0037012465 scopus 로고    scopus 로고
    • Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
    • Higashi M., Veenstra D., Kondo L., Wittkowsky A., Srinouanprachanh S., Farin F., et al. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 287 (2002) 1690-1698
    • (2002) JAMA , vol.287 , pp. 1690-1698
    • Higashi, M.1    Veenstra, D.2    Kondo, L.3    Wittkowsky, A.4    Srinouanprachanh, S.5    Farin, F.6
  • 123
    • 0036194038 scopus 로고    scopus 로고
    • The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin
    • Tabrizi A., Zehnbauer B., Borecki I., McGrath S., Buchman T., and Freeman B. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg 194 (2002) 267-273
    • (2002) J Am Coll Surg , vol.194 , pp. 267-273
    • Tabrizi, A.1    Zehnbauer, B.2    Borecki, I.3    McGrath, S.4    Buchman, T.5    Freeman, B.6
  • 124
    • 0742286803 scopus 로고    scopus 로고
    • Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
    • Zanger U., Raimundo S., and Eichelbaum M. Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmacol 369 (2004) 23-37
    • (2004) Naunyn Schmiedebergs Arch Pharmacol , vol.369 , pp. 23-37
    • Zanger, U.1    Raimundo, S.2    Eichelbaum, M.3
  • 125
    • 0023854270 scopus 로고
    • Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
    • Gonzalez F., Skoda R., Kimura S., Umeno M., Zanger U., Nebert D., et al. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature 331 (1988) 442-446
    • (1988) Nature , vol.331 , pp. 442-446
    • Gonzalez, F.1    Skoda, R.2    Kimura, S.3    Umeno, M.4    Zanger, U.5    Nebert, D.6
  • 126
    • 0025114258 scopus 로고
    • Identification of the primary gene defect at the cytochrome P450 CYP2D locus
    • Gough A., Miles J., Spurr N., Moss J., Gaedigk A., Eichelbaum M., et al. Identification of the primary gene defect at the cytochrome P450 CYP2D locus. Nature 347 (1990) 773-776
    • (1990) Nature , vol.347 , pp. 773-776
    • Gough, A.1    Miles, J.2    Spurr, N.3    Moss, J.4    Gaedigk, A.5    Eichelbaum, M.6
  • 127
    • 0026629691 scopus 로고
    • Evolution of a highly polymorphic human cytochrome P450 gene cluster: CYP2D6
    • Heim M., and Meyer U. Evolution of a highly polymorphic human cytochrome P450 gene cluster: CYP2D6. Genomics 14 (1992) 49-58
    • (1992) Genomics , vol.14 , pp. 49-58
    • Heim, M.1    Meyer, U.2
  • 128
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I., Lundqvist E., Bertilsson L., Dahl M., Sjoqvist F., and Ingelman-Sundberg M. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 90 (1993) 11825-11829
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.4    Sjoqvist, F.5    Ingelman-Sundberg, M.6
  • 129
    • 0024796958 scopus 로고
    • The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene
    • Kimura S., Umeno M., Skoda R., Meyer U., and Gonzalez F. The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. Am J Hum Genet 45 (1989) 889-904
    • (1989) Am J Hum Genet , vol.45 , pp. 889-904
    • Kimura, S.1    Umeno, M.2    Skoda, R.3    Meyer, U.4    Gonzalez, F.5
  • 130
    • 0030860004 scopus 로고    scopus 로고
    • Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution
    • Marez D., Legrand M., Sabbagh N., Lo Guidice J., Spire C., Broly F., et al. Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics 7 (1997) 193-202
    • (1997) Pharmacogenetics , vol.7 , pp. 193-202
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Lo Guidice, J.4    Spire, C.5    Broly, F.6
  • 131
    • 0033790979 scopus 로고    scopus 로고
    • Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6
    • Raimundo S., Fischer J., Eichelbaum M., Griese E., Schwab M., and Zanger U. Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6. Pharmacogenetics 10 (2000) 577-581
    • (2000) Pharmacogenetics , vol.10 , pp. 577-581
    • Raimundo, S.1    Fischer, J.2    Eichelbaum, M.3    Griese, E.4    Schwab, M.5    Zanger, U.6
  • 133
    • 0034790063 scopus 로고    scopus 로고
    • Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6
    • Zanger U., Fischer J., Raimundo S., Stuven T., Evert B., Schwab M., et al. Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6. Pharmacogenetics 11 (2001) 573-585
    • (2001) Pharmacogenetics , vol.11 , pp. 573-585
    • Zanger, U.1    Fischer, J.2    Raimundo, S.3    Stuven, T.4    Evert, B.5    Schwab, M.6
  • 134
    • 0023684586 scopus 로고
    • Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man
    • Zanger U., Vilbois F., Hardwick J., and Meyer U. Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man. Biochemistry 27 (1988) 5447-5454
    • (1988) Biochemistry , vol.27 , pp. 5447-5454
    • Zanger, U.1    Vilbois, F.2    Hardwick, J.3    Meyer, U.4
  • 135
    • 3543014421 scopus 로고    scopus 로고
    • A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects
    • Raimundo S., Toscano C., Klein K., Fischer J., Griese E., Eichelbaum M., et al. A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects. Clin Pharmacol Ther 76 (2004) 128-138
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 128-138
    • Raimundo, S.1    Toscano, C.2    Klein, K.3    Fischer, J.4    Griese, E.5    Eichelbaum, M.6
  • 136
    • 15744393886 scopus 로고    scopus 로고
    • Inter-individual variation of several cytochrome P450 2D6 splice variants in human liver
    • Denson J., Wu Y., Yang W., and Zhang J. Inter-individual variation of several cytochrome P450 2D6 splice variants in human liver. Biochem Biophys Res Commun 330 (2005) 498-504
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 498-504
    • Denson, J.1    Wu, Y.2    Yang, W.3    Zhang, J.4
  • 137
    • 3042641834 scopus 로고    scopus 로고
    • A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P450 2D7 that demethylates codeine to morphine
    • Pai H., Kommaddi R., Chinta S., Mori T., Boyd M., and Ravindranath V. A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P450 2D7 that demethylates codeine to morphine. J Biol Chem 279 (2004) 27383-27389
    • (2004) J Biol Chem , vol.279 , pp. 27383-27389
    • Pai, H.1    Kommaddi, R.2    Chinta, S.3    Mori, T.4    Boyd, M.5    Ravindranath, V.6
  • 138
    • 11244346108 scopus 로고    scopus 로고
    • Decreased levels of cytochrome P450 2E1-derived eicosanoids sensitize renal arteries to constrictor agonists in spontaneously hypertensive rats
    • Zhang F., Deng H., Kemp R., Singh H., Gopal V., Falck J., et al. Decreased levels of cytochrome P450 2E1-derived eicosanoids sensitize renal arteries to constrictor agonists in spontaneously hypertensive rats. Hypertension 45 (2005) 103-108
    • (2005) Hypertension , vol.45 , pp. 103-108
    • Zhang, F.1    Deng, H.2    Kemp, R.3    Singh, H.4    Gopal, V.5    Falck, J.6
  • 139
    • 0038650989 scopus 로고    scopus 로고
    • Verapamil: Metabolism in cultures of primary human coronary arterial endothelial cells
    • Borlak J., Walles M., Levsen K., and Thum T. Verapamil: Metabolism in cultures of primary human coronary arterial endothelial cells. Drug Metab Dispos 31 (2003) 888-891
    • (2003) Drug Metab Dispos , vol.31 , pp. 888-891
    • Borlak, J.1    Walles, M.2    Levsen, K.3    Thum, T.4
  • 140
    • 10444229539 scopus 로고    scopus 로고
    • Role of cytochromes P450 in chemical toxicity and oxidative stress: Studies with CYP2E1
    • Gonzalez F. Role of cytochromes P450 in chemical toxicity and oxidative stress: Studies with CYP2E1. Mutat Res 569 (2005) 101-110
    • (2005) Mutat Res , vol.569 , pp. 101-110
    • Gonzalez, F.1
  • 141
    • 0031737607 scopus 로고    scopus 로고
    • A genetic polymorphism in the regulatory sequences of human CYP2E1: Association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake
    • McCarver D., Byun R., Hines R., Hichme M., and Wegenek W. A genetic polymorphism in the regulatory sequences of human CYP2E1: Association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake. Toxicol Appl Pharmacol 152 (1998) 276-281
    • (1998) Toxicol Appl Pharmacol , vol.152 , pp. 276-281
    • McCarver, D.1    Byun, R.2    Hines, R.3    Hichme, M.4    Wegenek, W.5
  • 143
    • 0033600711 scopus 로고    scopus 로고
    • Structural and functional characterization of the 5′-flanking region of the rat and human cytochrome P450 2E1 genes: Identification of a polymorphic repeat in the human gene
    • Hu Y., Hakkola J., Oscarson M., and Ingelman-Sundberg M. Structural and functional characterization of the 5′-flanking region of the rat and human cytochrome P450 2E1 genes: Identification of a polymorphic repeat in the human gene. Biochem Biophys Res Commun 263 (1999) 286-293
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 286-293
    • Hu, Y.1    Hakkola, J.2    Oscarson, M.3    Ingelman-Sundberg, M.4
  • 144
    • 29244473583 scopus 로고    scopus 로고
    • Molecular cloning and expression of novel alternatively spliced cytochrome P450 2E1 mRNAs in humans
    • Bauer M., Herbarth O., Aust G., and Graebsch C. Molecular cloning and expression of novel alternatively spliced cytochrome P450 2E1 mRNAs in humans. Mol Cell Biochem 280 (2005) 201-207
    • (2005) Mol Cell Biochem , vol.280 , pp. 201-207
    • Bauer, M.1    Herbarth, O.2    Aust, G.3    Graebsch, C.4
  • 145
    • 0033588034 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids
    • Node K., Huo Y., Ruan X., Yang B., Spiecker M., Ley K., et al. Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science 285 (1999) 1276-1279
    • (1999) Science , vol.285 , pp. 1276-1279
    • Node, K.1    Huo, Y.2    Ruan, X.3    Yang, B.4    Spiecker, M.5    Ley, K.6
  • 146
    • 0032476637 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation
    • Oltman C., Weintraub N., VanRollins M., and Dellsperger K. Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation. Circ Res 83 (1998) 932-939
    • (1998) Circ Res , vol.83 , pp. 932-939
    • Oltman, C.1    Weintraub, N.2    VanRollins, M.3    Dellsperger, K.4
  • 147
    • 0034736577 scopus 로고    scopus 로고
    • The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
    • Finta C., and Zaphiropoulos P. The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons. Gene 260 (2000) 13-23
    • (2000) Gene , vol.260 , pp. 13-23
    • Finta, C.1    Zaphiropoulos, P.2
  • 149
    • 0036786382 scopus 로고    scopus 로고
    • Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA
    • Koch I., Weil R., Wolbold R., Brockmoller J., Hustert E., Burk O., et al. Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA. Drug Metab Dispos 30 (2002) 1108-1114
    • (2002) Drug Metab Dispos , vol.30 , pp. 1108-1114
    • Koch, I.1    Weil, R.2    Wolbold, R.3    Brockmoller, J.4    Hustert, E.5    Burk, O.6
  • 150
    • 31344443943 scopus 로고    scopus 로고
    • Significance of the minor cytochrome P450 3A isoforms
    • Daly A. Significance of the minor cytochrome P450 3A isoforms. Clin Pharmacokinet 45 (2006) 13-31
    • (2006) Clin Pharmacokinet , vol.45 , pp. 13-31
    • Daly, A.1
  • 151
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • Kuehl P., Zhang J., Lin Y., Lamba J., Assem M., Schuetz J., et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 27 (2001) 383-391
    • (2001) Nat Genet , vol.27 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3    Lamba, J.4    Assem, M.5    Schuetz, J.6
  • 152
    • 0030750270 scopus 로고    scopus 로고
    • Expression of CYP3A in the human liver-evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth
    • Lacroix D., Sonnier M., Moncion A., Cheron G., and Cresteil T. Expression of CYP3A in the human liver-evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth. Eur J Biochem 247 (1997) 625-634
    • (1997) Eur J Biochem , vol.247 , pp. 625-634
    • Lacroix, D.1    Sonnier, M.2    Moncion, A.3    Cheron, G.4    Cresteil, T.5
  • 153
    • 0028175687 scopus 로고
    • Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver
    • Schuetz J., Beach D., and Guzelian P. Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver. Pharmacogenetics 4 (1994) 11-20
    • (1994) Pharmacogenetics , vol.4 , pp. 11-20
    • Schuetz, J.1    Beach, D.2    Guzelian, P.3
  • 155
    • 0035197548 scopus 로고    scopus 로고
    • Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos
    • Dai D., Tang J., Rose R., Hodgson E., Bienstock R., Mohrenweiser H., et al. Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos. J Pharmacol Exp Ther 299 (2001) 825-831
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 825-831
    • Dai, D.1    Tang, J.2    Rose, R.3    Hodgson, E.4    Bienstock, R.5    Mohrenweiser, H.6
  • 156
    • 0035102719 scopus 로고    scopus 로고
    • CYP3A genetics in drug metabolism
    • Eichelbaum M., and Burk O. CYP3A genetics in drug metabolism. Nat Med 7 (2001) 285-287
    • (2001) Nat Med , vol.7 , pp. 285-287
    • Eichelbaum, M.1    Burk, O.2
  • 157
    • 0037131879 scopus 로고    scopus 로고
    • Genetic contribution to variable human CYP3A-mediated metabolism
    • Lamba J., Lin Y., Schuetz E., and Thummel K. Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev 54 (2002) 1271-1294
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1271-1294
    • Lamba, J.1    Lin, Y.2    Schuetz, E.3    Thummel, K.4
  • 158
    • 0345643389 scopus 로고    scopus 로고
    • Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5′-upstream regulatory region
    • Westlind A., Lofberg L., Tindberg N., Andersson T., and Ingelman-Sundberg M. Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5′-upstream regulatory region. Biochem Biophys Res Commun 259 (1999) 201-205
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 201-205
    • Westlind, A.1    Lofberg, L.2    Tindberg, N.3    Andersson, T.4    Ingelman-Sundberg, M.5
  • 159
    • 0038128342 scopus 로고    scopus 로고
    • Constitutive androstane receptor and pregnane X receptor gene expression in human liver: Interindividual variability and correlation with CYP2B6 mRNA levels
    • Chang T., Bandiera S., and Chen J. Constitutive androstane receptor and pregnane X receptor gene expression in human liver: Interindividual variability and correlation with CYP2B6 mRNA levels. Drug Metab Dispos 31 (2003) 7-10
    • (2003) Drug Metab Dispos , vol.31 , pp. 7-10
    • Chang, T.1    Bandiera, S.2    Chen, J.3
  • 160
    • 0035659943 scopus 로고    scopus 로고
    • Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor
    • Pascussi J., Drocourt L., Gerbal-Chaloin S., Fabre J., Maurel P., and Vilarem M. Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor. Eur J Biochem 268 (2001) 6346-6358
    • (2001) Eur J Biochem , vol.268 , pp. 6346-6358
    • Pascussi, J.1    Drocourt, L.2    Gerbal-Chaloin, S.3    Fabre, J.4    Maurel, P.5    Vilarem, M.6
  • 164
    • 0342468270 scopus 로고    scopus 로고
    • Detection of CYP3A5 allelic variant: A candidate for the polymorphic expression of the protein?
    • Jounaidi Y., Hyrailles V., Gervot L., and Maurel P. Detection of CYP3A5 allelic variant: A candidate for the polymorphic expression of the protein?. Biochem Biophys Res Commun 221 (1996) 466-470
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 466-470
    • Jounaidi, Y.1    Hyrailles, V.2    Gervot, L.3    Maurel, P.4
  • 165
    • 0041421011 scopus 로고    scopus 로고
    • CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults
    • Givens R., Lin Y., Dowling A., Thummel K., Lamba J., Schuetz E., et al. CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults. J Appl Physiol 95 (2003) 1297-1300
    • (2003) J Appl Physiol , vol.95 , pp. 1297-1300
    • Givens, R.1    Lin, Y.2    Dowling, A.3    Thummel, K.4    Lamba, J.5    Schuetz, E.6
  • 166
    • 3543042787 scopus 로고    scopus 로고
    • Genetic variability in CYP3A5 and its possible consequences
    • Xie H., Wood A., Kim R., Stein C., and Wilkinson G. Genetic variability in CYP3A5 and its possible consequences. Pharmacogenomics 5 (2004) 243-272
    • (2004) Pharmacogenomics , vol.5 , pp. 243-272
    • Xie, H.1    Wood, A.2    Kim, R.3    Stein, C.4    Wilkinson, G.5
  • 168
    • 22244451696 scopus 로고    scopus 로고
    • CYP3A5 genotype is associated with diagnosis of hypertension in elderly patients: Data from the DEBATE Study
    • Kivisto K., Niemi M., Schaeffeler E., Pitkala K., Tilvis R., Fromm M., et al. CYP3A5 genotype is associated with diagnosis of hypertension in elderly patients: Data from the DEBATE Study. Am J Pharmacogenomics 5 (2005) 191-195
    • (2005) Am J Pharmacogenomics , vol.5 , pp. 191-195
    • Kivisto, K.1    Niemi, M.2    Schaeffeler, E.3    Pitkala, K.4    Tilvis, R.5    Fromm, M.6
  • 169
    • 27944467478 scopus 로고    scopus 로고
    • The role of the cytochrome P450 3A5 enzyme for blood pressure regulation in the general Caucasian population
    • Kreutz R., Zuurman M., Kain S., Bolbrinker J., de Jong P., and Navis G. The role of the cytochrome P450 3A5 enzyme for blood pressure regulation in the general Caucasian population. Pharmacogenet Genomics 15 (2005) 831-837
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 831-837
    • Kreutz, R.1    Zuurman, M.2    Kain, S.3    Bolbrinker, J.4    de Jong, P.5    Navis, G.6
  • 170
    • 19944431766 scopus 로고    scopus 로고
    • Association between the CYP3A5 genotype and blood pressure
    • Ho H., Pinto A., Hall S., Flockhart D., Li L., Skaar T., et al. Association between the CYP3A5 genotype and blood pressure. Hypertension 45 (2005) 294-298
    • (2005) Hypertension , vol.45 , pp. 294-298
    • Ho, H.1    Pinto, A.2    Hall, S.3    Flockhart, D.4    Li, L.5    Skaar, T.6
  • 171
    • 0024350111 scopus 로고
    • The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element
    • Kimura S., Hanioka N., Matsunaga E., and Gonzalez F. The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element. DNA 8 (1989) 503-516
    • (1989) DNA , vol.8 , pp. 503-516
    • Kimura, S.1    Hanioka, N.2    Matsunaga, E.3    Gonzalez, F.4
  • 172
    • 0024385160 scopus 로고
    • The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes
    • Kimura S., Hardwick J., Kozak C., and Gonzalez F. The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes. DNA 8 (1989) 517-525
    • (1989) DNA , vol.8 , pp. 517-525
    • Kimura, S.1    Hardwick, J.2    Kozak, C.3    Gonzalez, F.4
  • 173
    • 0031808169 scopus 로고    scopus 로고
    • Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: Involvement of CYP4F2 and CYP4A11
    • Powell P., Wolf I., Jin R., and Lasker J. Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: Involvement of CYP4F2 and CYP4A11. J Pharmacol Exp Ther 285 (1998) 1327-1336
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 1327-1336
    • Powell, P.1    Wolf, I.2    Jin, R.3    Lasker, J.4
  • 174
    • 0031049745 scopus 로고    scopus 로고
    • The cytochrome P450 4 (CYP4) family
    • Simpson A. The cytochrome P450 4 (CYP4) family. Gen Pharmacol 28 (1997) 351-359
    • (1997) Gen Pharmacol , vol.28 , pp. 351-359
    • Simpson, A.1
  • 175
    • 9044254525 scopus 로고    scopus 로고
    • P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
    • Nelson D., Koymans L., Kamataki T., Stegeman J., Feyereisen R., Waxman D., et al. P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6 (1996) 1-42
    • (1996) Pharmacogenetics , vol.6 , pp. 1-42
    • Nelson, D.1    Koymans, L.2    Kamataki, T.3    Stegeman, J.4    Feyereisen, R.5    Waxman, D.6
  • 176
    • 0033955218 scopus 로고    scopus 로고
    • Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases
    • Hoch U., Zhang Z., Kroetz D., and Ortiz de Montellano P. Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases. Arch Biochem Biophys 373 (2000) 63-71
    • (2000) Arch Biochem Biophys , vol.373 , pp. 63-71
    • Hoch, U.1    Zhang, Z.2    Kroetz, D.3    Ortiz de Montellano, P.4
  • 177
    • 0027739613 scopus 로고
    • Complete cDNA sequence and cDNA-directed expression of CYP4A11, a fatty acid omega-hydroxylase expressed in human kidney
    • Imaoka S., Ogawa H., Kimura S., and Gonzalez F. Complete cDNA sequence and cDNA-directed expression of CYP4A11, a fatty acid omega-hydroxylase expressed in human kidney. DNA Cell Biol 12 (1993) 893-899
    • (1993) DNA Cell Biol , vol.12 , pp. 893-899
    • Imaoka, S.1    Ogawa, H.2    Kimura, S.3    Gonzalez, F.4
  • 178
    • 0036080081 scopus 로고    scopus 로고
    • P-450 metabolites of arachidonic acid in the control of cardiovascular function
    • Roman R. P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol Rev 82 (2002) 131-185
    • (2002) Physiol Rev , vol.82 , pp. 131-185
    • Roman, R.1
  • 179
    • 19944428214 scopus 로고    scopus 로고
    • Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension
    • Gainer J., Bellamine A., Dawson E., Womble K., Grant S., Wang Y., et al. Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. Circulation 111 (2005) 63-69
    • (2005) Circulation , vol.111 , pp. 63-69
    • Gainer, J.1    Bellamine, A.2    Dawson, E.3    Womble, K.4    Grant, S.5    Wang, Y.6
  • 180
    • 31944441144 scopus 로고    scopus 로고
    • Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy
    • Mayer B., Lieb W., Gotz A., Konig I., Aherrahrou Z., Thiemig A., et al. Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy. Hypertension 46 (2005) 766-771
    • (2005) Hypertension , vol.46 , pp. 766-771
    • Mayer, B.1    Lieb, W.2    Gotz, A.3    Konig, I.4    Aherrahrou, Z.5    Thiemig, A.6
  • 182
    • 0036020994 scopus 로고    scopus 로고
    • Genetic polymorphism of the human cytochrome P450 CYP4B1: Evidence for a non-functional allelic variant
    • Lo-Guidice J., Allorge D., Cauffiez C., Chevalier D., Lafitte J., Lhermitte M., et al. Genetic polymorphism of the human cytochrome P450 CYP4B1: Evidence for a non-functional allelic variant. Pharmacogenetics 12 (2002) 367-374
    • (2002) Pharmacogenetics , vol.12 , pp. 367-374
    • Lo-Guidice, J.1    Allorge, D.2    Cauffiez, C.3    Chevalier, D.4    Lafitte, J.5    Lhermitte, M.6
  • 183
    • 0033921480 scopus 로고    scopus 로고
    • Characterization of human liver leukotriene B(4) omega-hydroxylase P450 (CYP4F2)
    • Kikuta Y., Kusunose E., and Kusunose M. Characterization of human liver leukotriene B(4) omega-hydroxylase P450 (CYP4F2). J Biochem (Tokyo) 127 (2000) 1047-1052
    • (2000) J Biochem (Tokyo) , vol.127 , pp. 1047-1052
    • Kikuta, Y.1    Kusunose, E.2    Kusunose, M.3
  • 185
    • 0037376494 scopus 로고    scopus 로고
    • Leukotriene B4 omega-side chain hydroxylation by CYP4F5 and CYP4F6
    • Bylund J., Harder A., Maier K., Roman R., and Harder D. Leukotriene B4 omega-side chain hydroxylation by CYP4F5 and CYP4F6. Arch Biochem Biophys 412 (2003) 34-41
    • (2003) Arch Biochem Biophys , vol.412 , pp. 34-41
    • Bylund, J.1    Harder, A.2    Maier, K.3    Roman, R.4    Harder, D.5
  • 186
    • 0034698139 scopus 로고    scopus 로고
    • Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides
    • Bylund J., Hidestrand M., Ingelman-Sundberg M., and Oliw E. Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides. J Biol Chem 275 (2000) 21844-21849
    • (2000) J Biol Chem , vol.275 , pp. 21844-21849
    • Bylund, J.1    Hidestrand, M.2    Ingelman-Sundberg, M.3    Oliw, E.4
  • 187
    • 0034809149 scopus 로고    scopus 로고
    • cDna cloning and expression of CYP4F12, a novel human cytochrome P450
    • Bylund J., Bylund M., and Oliw E. cDna cloning and expression of CYP4F12, a novel human cytochrome P450. Biochem Biophys Res Commun 280 (2001) 892-897
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 892-897
    • Bylund, J.1    Bylund, M.2    Oliw, E.3
  • 188
    • 0036138172 scopus 로고    scopus 로고
    • Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes
    • Hashizume T., Imaoka S., Mise M., Terauchi Y., Fujii T., Miyazaki H., et al. Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes. J Pharmacol Exp Ther 300 (2002) 298-304
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 298-304
    • Hashizume, T.1    Imaoka, S.2    Mise, M.3    Terauchi, Y.4    Fujii, T.5    Miyazaki, H.6
  • 189
    • 0033597849 scopus 로고    scopus 로고
    • Expression of the CYP4F3 gene. Tissue-specific splicing and alternative promoters generate high and low K(m) forms of leukotriene B(4) omega-hydroxylase
    • Christmas P., Ursino S., Fox J., and Soberman R. Expression of the CYP4F3 gene. Tissue-specific splicing and alternative promoters generate high and low K(m) forms of leukotriene B(4) omega-hydroxylase. J Biol Chem 274 (1999) 21191-21199
    • (1999) J Biol Chem , vol.274 , pp. 21191-21199
    • Christmas, P.1    Ursino, S.2    Fox, J.3    Soberman, R.4
  • 190
    • 0035851164 scopus 로고    scopus 로고
    • Alternative splicing determines the function of CYP4F3 by switching substrate specificity
    • Christmas P., Jones J., Patten C., Rock D., Zheng Y., Cheng S., et al. Alternative splicing determines the function of CYP4F3 by switching substrate specificity. J Biol Chem 276 (2001) 38166-38172
    • (2001) J Biol Chem , vol.276 , pp. 38166-38172
    • Christmas, P.1    Jones, J.2    Patten, C.3    Rock, D.4    Zheng, Y.5    Cheng, S.6
  • 191
    • 0035154850 scopus 로고    scopus 로고
    • The potential pharmacological and toxicological impact of P450 screening
    • Riley R. The potential pharmacological and toxicological impact of P450 screening. Curr Opin Drug Discov Devel 4 (2001) 45-54
    • (2001) Curr Opin Drug Discov Devel , vol.4 , pp. 45-54
    • Riley, R.1
  • 193
    • 33644652183 scopus 로고    scopus 로고
    • Sorting out the roles of PPARalpha in energy metabolism and vascular homeostasis
    • Lefebvre P., Chinetti G., Fruchart J., and Staels B. Sorting out the roles of PPARalpha in energy metabolism and vascular homeostasis. J Clin Invest 116 (2006) 571-580
    • (2006) J Clin Invest , vol.116 , pp. 571-580
    • Lefebvre, P.1    Chinetti, G.2    Fruchart, J.3    Staels, B.4
  • 194
    • 0028239139 scopus 로고
    • Interindividual difference in expression of human Ah receptor and related P450 genes
    • Hayashi S., Watanabe J., Nakachi K., Eguchi H., Gotoh O., and Kawajiri K. Interindividual difference in expression of human Ah receptor and related P450 genes. Carcinogenesis 15 (1994) 801-806
    • (1994) Carcinogenesis , vol.15 , pp. 801-806
    • Hayashi, S.1    Watanabe, J.2    Nakachi, K.3    Eguchi, H.4    Gotoh, O.5    Kawajiri, K.6
  • 195
    • 0344120180 scopus 로고    scopus 로고
    • Association of aryl hydrocarbon receptor and cytochrome P4501B1 expressions in human non-small cell lung cancers
    • Lin P., Chang H., Ho W., Wu M., and Su J. Association of aryl hydrocarbon receptor and cytochrome P4501B1 expressions in human non-small cell lung cancers. Lung Cancer 42 (2003) 255-261
    • (2003) Lung Cancer , vol.42 , pp. 255-261
    • Lin, P.1    Chang, H.2    Ho, W.3    Wu, M.4    Su, J.5
  • 196
    • 0028891272 scopus 로고
    • Ah receptor role in TCDD toxicity: Still some mysteries but no myth-a reply to the commentary by Dr. L.W.D. Weber and Dr. B.U. Stahl
    • Okey A., Riddick D., and Harper P. Ah receptor role in TCDD toxicity: Still some mysteries but no myth-a reply to the commentary by Dr. L.W.D. Weber and Dr. B.U. Stahl. Toxicol Lett 75 (1995) 249-254
    • (1995) Toxicol Lett , vol.75 , pp. 249-254
    • Okey, A.1    Riddick, D.2    Harper, P.3
  • 197
  • 198
    • 0023617544 scopus 로고
    • Ah receptor in human placenta: Stabilization by molybdate and characterization of binding of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo(a)pyrene
    • Manchester D., Gordon S., Golas C., Roberts E., and Okey A. Ah receptor in human placenta: Stabilization by molybdate and characterization of binding of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo(a)pyrene. Cancer Res 47 (1987) 4861-4868
    • (1987) Cancer Res , vol.47 , pp. 4861-4868
    • Manchester, D.1    Gordon, S.2    Golas, C.3    Roberts, E.4    Okey, A.5
  • 199
    • 0033658607 scopus 로고    scopus 로고
    • An uncommon phenotype of poor inducibility of CYP1A1 in human lung is not ascribable to polymorphisms in the AHR, ARNT, or CYP1A1 genes
    • Anttila S., Lei X., Elovaara E., Karjalainen A., Sun W., Vainio H., et al. An uncommon phenotype of poor inducibility of CYP1A1 in human lung is not ascribable to polymorphisms in the AHR, ARNT, or CYP1A1 genes. Pharmacogenetics 10 (2000) 741-751
    • (2000) Pharmacogenetics , vol.10 , pp. 741-751
    • Anttila, S.1    Lei, X.2    Elovaara, E.3    Karjalainen, A.4    Sun, W.5    Vainio, H.6
  • 200
    • 0036274035 scopus 로고    scopus 로고
    • Variability of the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene
    • Scheel J., Hussong R., Schrenk D., and Schmitz H. Variability of the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene. J Hum Genet 47 (2002) 217-224
    • (2002) J Hum Genet , vol.47 , pp. 217-224
    • Scheel, J.1    Hussong, R.2    Schrenk, D.3    Schmitz, H.4
  • 201
    • 0034987564 scopus 로고    scopus 로고
    • Human arylhydrocarbon receptor repressor (AHRR) gene: Genomic structure and analysis of polymorphism in endometriosis
    • Watanabe T., Imoto I., Kosugi Y., Fukuda Y., Mimura J., Fujii Y., et al. Human arylhydrocarbon receptor repressor (AHRR) gene: Genomic structure and analysis of polymorphism in endometriosis. J Hum Genet 46 (2001) 342-346
    • (2001) J Hum Genet , vol.46 , pp. 342-346
    • Watanabe, T.1    Imoto, I.2    Kosugi, Y.3    Fukuda, Y.4    Mimura, J.5    Fujii, Y.6
  • 202
    • 20644435582 scopus 로고    scopus 로고
    • Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes
    • Okey A., Boutros P., and Harper P. Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes. Pharmacogenet Genomics 15 (2005) 371-379
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 371-379
    • Okey, A.1    Boutros, P.2    Harper, P.3
  • 203
    • 24644461253 scopus 로고    scopus 로고
    • Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: The case of the aryl hydrocarbon receptor
    • Okey A., Franc M., Moffat I., Tijet N., Boutros P., Korkalainen M., et al. Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: The case of the aryl hydrocarbon receptor. Toxicol Appl Pharmacol 207 (2005) 43-51
    • (2005) Toxicol Appl Pharmacol , vol.207 , pp. 43-51
    • Okey, A.1    Franc, M.2    Moffat, I.3    Tijet, N.4    Boutros, P.5    Korkalainen, M.6
  • 204
    • 30144435401 scopus 로고    scopus 로고
    • Pregnane X receptor-mediated transcription
    • Chang T., and Waxman D. Pregnane X receptor-mediated transcription. Methods Enzymol 400 (2005) 588-598
    • (2005) Methods Enzymol , vol.400 , pp. 588-598
    • Chang, T.1    Waxman, D.2
  • 205
    • 0036799870 scopus 로고    scopus 로고
    • The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism
    • Kliewer S., Goodwin B., and Willson T. The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism. Endocr Rev 23 (2002) 687-702
    • (2002) Endocr Rev , vol.23 , pp. 687-702
    • Kliewer, S.1    Goodwin, B.2    Willson, T.3
  • 206
    • 0033199499 scopus 로고    scopus 로고
    • P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, and PPAR
    • Waxman D. P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, and PPAR. Arch Biochem Biophys 369 (1999) 11-23
    • (1999) Arch Biochem Biophys , vol.369 , pp. 11-23
    • Waxman, D.1
  • 207
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann J., McKee D., Watson M., Willson T., Moore J., and Kliewer S. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest 102 (1998) 1016-1023
    • (1998) J Clin Invest , vol.102 , pp. 1016-1023
    • Lehmann, J.1    McKee, D.2    Watson, M.3    Willson, T.4    Moore, J.5    Kliewer, S.6
  • 208
    • 1642579509 scopus 로고    scopus 로고
    • Lessons from the CYP3A4 promoter
    • Schuetz E. Lessons from the CYP3A4 promoter. Mol Pharmacol 65 (2004) 279-281
    • (2004) Mol Pharmacol , vol.65 , pp. 279-281
    • Schuetz, E.1
  • 209
    • 0036171965 scopus 로고    scopus 로고
    • Regulation of cyp3a gene transcription by the pregnane x receptor
    • Goodwin B., Redinbo M., and Kliewer S. Regulation of cyp3a gene transcription by the pregnane x receptor. Annu Rev Pharmacol Toxicol 42 (2002) 1-23
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 1-23
    • Goodwin, B.1    Redinbo, M.2    Kliewer, S.3
  • 210
    • 0035038008 scopus 로고    scopus 로고
    • Phenobarbital response elements of cytochrome P450 genes and nuclear receptors
    • Sueyoshi T., and Negishi M. Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. Annu Rev Pharmacol Toxicol 41 (2001) 123-143
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 123-143
    • Sueyoshi, T.1    Negishi, M.2
  • 211
    • 0037333974 scopus 로고    scopus 로고
    • Molecular mechanism of nuclear translocation of an orphan nuclear receptor, SXR
    • Kawana K., Ikuta T., Kobayashi Y., Gotoh O., Takeda K., and Kawajiri K. Molecular mechanism of nuclear translocation of an orphan nuclear receptor, SXR. Mol Pharmacol 63 (2003) 524-531
    • (2003) Mol Pharmacol , vol.63 , pp. 524-531
    • Kawana, K.1    Ikuta, T.2    Kobayashi, Y.3    Gotoh, O.4    Takeda, K.5    Kawajiri, K.6
  • 212
    • 8344219885 scopus 로고    scopus 로고
    • Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver
    • Squires E., Sueyoshi T., and Negishi M. Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver. J Biol Chem 279 (2004) 49307-49314
    • (2004) J Biol Chem , vol.279 , pp. 49307-49314
    • Squires, E.1    Sueyoshi, T.2    Negishi, M.3
  • 213
    • 0034782509 scopus 로고    scopus 로고
    • Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor
    • Staudinger J., Liu Y., Madan A., Habeebu S., and Klaassen C. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor. Drug Metab Dispos 29 (2001) 1467-1472
    • (2001) Drug Metab Dispos , vol.29 , pp. 1467-1472
    • Staudinger, J.1    Liu, Y.2    Madan, A.3    Habeebu, S.4    Klaassen, C.5
  • 214
    • 0035853057 scopus 로고    scopus 로고
    • An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
    • Xie W., Radominska-Pandya A., Shi Y., Simon C., Nelson M., Ong E., et al. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci USA 98 (2001) 3375-3380
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3375-3380
    • Xie, W.1    Radominska-Pandya, A.2    Shi, Y.3    Simon, C.4    Nelson, M.5    Ong, E.6
  • 215
    • 1642498313 scopus 로고    scopus 로고
    • Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): One variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region
    • Koyano S., Kurose K., Saito Y., Ozawa S., Hasegawa R., Komamura K., et al. Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): One variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region. Drug Metab Dispos 32 (2004) 149-154
    • (2004) Drug Metab Dispos , vol.32 , pp. 149-154
    • Koyano, S.1    Kurose, K.2    Saito, Y.3    Ozawa, S.4    Hasegawa, R.5    Komamura, K.6
  • 217
    • 1342344703 scopus 로고    scopus 로고
    • Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression
    • Gardner-Stephen D., Heydel J., Goyal A., Lu Y., Xie W., Lindblom T., et al. Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression. Drug Metab Dispos 32 (2004) 340-347
    • (2004) Drug Metab Dispos , vol.32 , pp. 340-347
    • Gardner-Stephen, D.1    Heydel, J.2    Goyal, A.3    Lu, Y.4    Xie, W.5    Lindblom, T.6
  • 218
    • 4444264038 scopus 로고    scopus 로고
    • PXR (NR1I2): Splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators
    • Lamba V., Yasuda K., Lamba J., Assem M., Davila J., Strom S., et al. PXR (NR1I2): Splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. Toxicol Appl Pharmacol 199 (2004) 251-265
    • (2004) Toxicol Appl Pharmacol , vol.199 , pp. 251-265
    • Lamba, V.1    Yasuda, K.2    Lamba, J.3    Assem, M.4    Davila, J.5    Strom, S.6
  • 219
    • 20044378331 scopus 로고    scopus 로고
    • 5′ diversity of human hepatic PXR (NR1I2) transcripts and identification of the major transcription initiation site
    • Kurose K., Koyano S., Ikeda S., Tohkin M., Hasegawa R., and Sawada J. 5′ diversity of human hepatic PXR (NR1I2) transcripts and identification of the major transcription initiation site. Mol Cell Biochem 273 (2005) 79-85
    • (2005) Mol Cell Biochem , vol.273 , pp. 79-85
    • Kurose, K.1    Koyano, S.2    Ikeda, S.3    Tohkin, M.4    Hasegawa, R.5    Sawada, J.6
  • 220
    • 0142089732 scopus 로고    scopus 로고
    • Alternative splicing within the ligand binding domain of the human constitutive androstane receptor
    • Savkur R., Wu Y., Bramlett K., Wang M., Yao S., Perkins D., et al. Alternative splicing within the ligand binding domain of the human constitutive androstane receptor. Mol Genet Metab 80 (2003) 216-226
    • (2003) Mol Genet Metab , vol.80 , pp. 216-226
    • Savkur, R.1    Wu, Y.2    Bramlett, K.3    Wang, M.4    Yao, S.5    Perkins, D.6
  • 221
    • 0037228093 scopus 로고    scopus 로고
    • Cytochrome-P450 phosphorylation as a functional switch
    • Oesch-Bartlomowicz B., and Oesch F. Cytochrome-P450 phosphorylation as a functional switch. Arch Biochem Biophys 409 (2003) 228-234
    • (2003) Arch Biochem Biophys , vol.409 , pp. 228-234
    • Oesch-Bartlomowicz, B.1    Oesch, F.2
  • 222
    • 27544490759 scopus 로고    scopus 로고
    • Phosphorylation of cytochromes P450: First discovery of a posttranslational modification of a drug-metabolizing enzyme
    • Oesch-Bartlomowicz B., and Oesch F. Phosphorylation of cytochromes P450: First discovery of a posttranslational modification of a drug-metabolizing enzyme. Biochem Biophys Res Commun 338 (2005) 446-449
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 446-449
    • Oesch-Bartlomowicz, B.1    Oesch, F.2
  • 223
    • 0020640860 scopus 로고
    • Phosphorylation of cytochrome-P-450-dependent monooxygenase components
    • Pyerin W., Wolf C., Kinzel V., Kubler D., and Oesch F. Phosphorylation of cytochrome-P-450-dependent monooxygenase components. Carcinogenesis 4 (1983) 573-576
    • (1983) Carcinogenesis , vol.4 , pp. 573-576
    • Pyerin, W.1    Wolf, C.2    Kinzel, V.3    Kubler, D.4    Oesch, F.5
  • 224
    • 0024587565 scopus 로고
    • Phosphorylation of carcinogen metabolizing enzymes: Regulation of the phosphorylation status of the major phenobarbital inducible cytochromes P-450 in hepatocytes
    • Bartlomowicz B., Waxman D., Utesch D., Oesch F., and Friedberg T. Phosphorylation of carcinogen metabolizing enzymes: Regulation of the phosphorylation status of the major phenobarbital inducible cytochromes P-450 in hepatocytes. Carcinogenesis 10 (1989) 225-228
    • (1989) Carcinogenesis , vol.10 , pp. 225-228
    • Bartlomowicz, B.1    Waxman, D.2    Utesch, D.3    Oesch, F.4    Friedberg, T.5
  • 225
    • 0026773423 scopus 로고
    • Hormone- and substrate-regulated intracellular degradation of cytochrome P450 (2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes
    • Eliasson E., Mkrtchian S., and Ingelman-Sundberg M. Hormone- and substrate-regulated intracellular degradation of cytochrome P450 (2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes. J Biol Chem 267 (1992) 15765-15769
    • (1992) J Biol Chem , vol.267 , pp. 15765-15769
    • Eliasson, E.1    Mkrtchian, S.2    Ingelman-Sundberg, M.3
  • 226
    • 0024507004 scopus 로고
    • Posttranslational modification of hepatic cytochrome P-450. Phosphorylation of phenobarbital-inducible P-450 forms PB-4 (IIB1) and PB-5 (IIB2) in isolated rat hepatocytes and in vivo
    • Koch J., and Waxman D. Posttranslational modification of hepatic cytochrome P-450. Phosphorylation of phenobarbital-inducible P-450 forms PB-4 (IIB1) and PB-5 (IIB2) in isolated rat hepatocytes and in vivo. Biochemistry 28 (1989) 3145-3152
    • (1989) Biochemistry , vol.28 , pp. 3145-3152
    • Koch, J.1    Waxman, D.2
  • 227
    • 0035545910 scopus 로고    scopus 로고
    • cAMP-dependent phosphorylation of CYP2B1 as a functional switch for cyclophosphamide activation and its hormonal control in vitro and in vivo
    • Oesch-Bartlomowicz B., Richter B., Becker R., Vogel S., Padma P., Hengstler J., et al. cAMP-dependent phosphorylation of CYP2B1 as a functional switch for cyclophosphamide activation and its hormonal control in vitro and in vivo. Int J Cancer 94 (2001) 733-742
    • (2001) Int J Cancer , vol.94 , pp. 733-742
    • Oesch-Bartlomowicz, B.1    Richter, B.2    Becker, R.3    Vogel, S.4    Padma, P.5    Hengstler, J.6
  • 228
    • 0023094803 scopus 로고
    • Posttranslational modifications of the cytochrome P-450 monooxygenase system
    • Pyerin W., Horn F., and Taniguchi H. Posttranslational modifications of the cytochrome P-450 monooxygenase system. J Cancer Res Clin Oncol 113 (1987) 155-159
    • (1987) J Cancer Res Clin Oncol , vol.113 , pp. 155-159
    • Pyerin, W.1    Horn, F.2    Taniguchi, H.3
  • 229
    • 0024401458 scopus 로고
    • Phosphorylation of hepatic phenobarbital-inducible cytochrome P-450
    • Pyerin W., and Taniguchi H. Phosphorylation of hepatic phenobarbital-inducible cytochrome P-450. EMBO J 8 (1989) 3003-3010
    • (1989) EMBO J , vol.8 , pp. 3003-3010
    • Pyerin, W.1    Taniguchi, H.2
  • 230
    • 0024550971 scopus 로고
    • Regio- and stereoselective regulation of monooxygenase activities by isoenzyme-selective phosphorylation of cytochrome P450
    • Bartlomowicz B., Friedberg T., Utesch D., Molitor E., Platt K., and Oesch F. Regio- and stereoselective regulation of monooxygenase activities by isoenzyme-selective phosphorylation of cytochrome P450. Biochem Biophys Res Commun 160 (1989) 46-52
    • (1989) Biochem Biophys Res Commun , vol.160 , pp. 46-52
    • Bartlomowicz, B.1    Friedberg, T.2    Utesch, D.3    Molitor, E.4    Platt, K.5    Oesch, F.6
  • 231
    • 0031867132 scopus 로고    scopus 로고
    • Differential modulation of CYP2E1 activity by cAMP-dependent protein kinase upon Ser129 replacement
    • Oesch-Bartlomowicz B., Padma P., Becker R., Richter B., Hengstler J., Freeman J., et al. Differential modulation of CYP2E1 activity by cAMP-dependent protein kinase upon Ser129 replacement. Exp Cell Res 242 (1998) 294-302
    • (1998) Exp Cell Res , vol.242 , pp. 294-302
    • Oesch-Bartlomowicz, B.1    Padma, P.2    Becker, R.3    Richter, B.4    Hengstler, J.5    Freeman, J.6
  • 232
    • 0030805966 scopus 로고    scopus 로고
    • Control of the mutagenicity of aromatic amines by protein kinases and phosphatases. I. The protein phosphatase inhibitors okadaic acid and ortho-vanadate drastically reduce the mutagenicity of aromatic amines
    • Oesch-Bartlomowicz B., Arens H., Richter B., Hengstler J., and Oesch F. Control of the mutagenicity of aromatic amines by protein kinases and phosphatases. I. The protein phosphatase inhibitors okadaic acid and ortho-vanadate drastically reduce the mutagenicity of aromatic amines. Arch Toxicol 71 (1997) 601-611
    • (1997) Arch Toxicol , vol.71 , pp. 601-611
    • Oesch-Bartlomowicz, B.1    Arens, H.2    Richter, B.3    Hengstler, J.4    Oesch, F.5
  • 234
    • 4444367613 scopus 로고    scopus 로고
    • Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter
    • Abdel-Razzak Z., Garlatti M., Aggerbeck M., and Barouki R. Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter. Biochem Pharmacol 68 (2004) 1371-1381
    • (2004) Biochem Pharmacol , vol.68 , pp. 1371-1381
    • Abdel-Razzak, Z.1    Garlatti, M.2    Aggerbeck, M.3    Barouki, R.4
  • 235
    • 0027443904 scopus 로고
    • Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
    • Abdel-Razzak Z., Loyer P., Fautrel A., Gautier J., Corcos L., Turlin B., et al. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol Pharmacol 44 (1993) 707-715
    • (1993) Mol Pharmacol , vol.44 , pp. 707-715
    • Abdel-Razzak, Z.1    Loyer, P.2    Fautrel, A.3    Gautier, J.4    Corcos, L.5    Turlin, B.6
  • 236
    • 0031409592 scopus 로고    scopus 로고
    • Regulation of cytochromes P450 during inflammation and infection
    • Morgan E. Regulation of cytochromes P450 during inflammation and infection. Drug Metab Rev 29 (1997) 1129-1188
    • (1997) Drug Metab Rev , vol.29 , pp. 1129-1188
    • Morgan, E.1
  • 237
    • 0029126915 scopus 로고
    • Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture
    • Muntane-Relat J., Ourlin J., Domergue J., and Maurel P. Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture. Hepatology 22 (1995) 1143-1153
    • (1995) Hepatology , vol.22 , pp. 1143-1153
    • Muntane-Relat, J.1    Ourlin, J.2    Domergue, J.3    Maurel, P.4
  • 238
    • 0030834106 scopus 로고    scopus 로고
    • Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women
    • Shedlofsky S., Israel B., Tosheva R., and Blouin R. Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women. Br J Clin Pharmacol 43 (1997) 627-632
    • (1997) Br J Clin Pharmacol , vol.43 , pp. 627-632
    • Shedlofsky, S.1    Israel, B.2    Tosheva, R.3    Blouin, R.4
  • 240
    • 0033940547 scopus 로고    scopus 로고
    • Hepatic and central nervous system cytochrome P450 are down-regulated during lipopolysaccharide-evoked localized inflammation in brain
    • Renton K., and Nicholson T. Hepatic and central nervous system cytochrome P450 are down-regulated during lipopolysaccharide-evoked localized inflammation in brain. J Pharmacol Exp Ther 294 (2000) 524-530
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 524-530
    • Renton, K.1    Nicholson, T.2
  • 241
    • 0029808476 scopus 로고    scopus 로고
    • Induction of cytochrome P450 2E1 expression in rat and gerbil astrocytes by inflammatory factors and ischemic injury
    • Tindberg N., Ingelman-Sundberg M., Baldwin H., and Cross A. Induction of cytochrome P450 2E1 expression in rat and gerbil astrocytes by inflammatory factors and ischemic injury. Mol Pharmacol 50 (1996) 1065-1072
    • (1996) Mol Pharmacol , vol.50 , pp. 1065-1072
    • Tindberg, N.1    Ingelman-Sundberg, M.2    Baldwin, H.3    Cross, A.4
  • 242
    • 0031876486 scopus 로고    scopus 로고
    • Differential alterations in levels of hepatic microsomal cytochrome P450 isozymes following intracerebroventricular injection of bacterial lipopolysaccharide in rats
    • Shimamoto Y., Kitamura H., Hoshi H., Kazusaka A., Funae Y., Imaoka S., et al. Differential alterations in levels of hepatic microsomal cytochrome P450 isozymes following intracerebroventricular injection of bacterial lipopolysaccharide in rats. Arch Toxicol 72 (1998) 492-498
    • (1998) Arch Toxicol , vol.72 , pp. 492-498
    • Shimamoto, Y.1    Kitamura, H.2    Hoshi, H.3    Kazusaka, A.4    Funae, Y.5    Imaoka, S.6
  • 243
    • 0032919795 scopus 로고    scopus 로고
    • Mechanism of decrease in levels of hepatic P450 isozymes induced by intracerebral endotoxin: Independence from sympathetic nervous and adrenocortical systems
    • Shimamoto Y., Kitamura H., Iwai M., Saito M., Kazusaka A., and Fujita S. Mechanism of decrease in levels of hepatic P450 isozymes induced by intracerebral endotoxin: Independence from sympathetic nervous and adrenocortical systems. Arch Toxicol 73 (1999) 41-49
    • (1999) Arch Toxicol , vol.73 , pp. 41-49
    • Shimamoto, Y.1    Kitamura, H.2    Iwai, M.3    Saito, M.4    Kazusaka, A.5    Fujita, S.6
  • 244
    • 0027185531 scopus 로고
    • Stable expression of human cytochrome P450 2E1 in HepG2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates
    • Dai Y., Rashba-Step J., and Cederbaum A. Stable expression of human cytochrome P450 2E1 in HepG2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates. Biochemistry 32 (1993) 6928-6937
    • (1993) Biochemistry , vol.32 , pp. 6928-6937
    • Dai, Y.1    Rashba-Step, J.2    Cederbaum, A.3
  • 245
    • 0018817225 scopus 로고
    • Oxygen activation by cytochrome P-450
    • White R., and Coon M. Oxygen activation by cytochrome P-450. Annu Rev Biochem 49 (1980) 315-356
    • (1980) Annu Rev Biochem , vol.49 , pp. 315-356
    • White, R.1    Coon, M.2
  • 246
    • 0030006304 scopus 로고    scopus 로고
    • Induction of cytochrome P4501A1 by 2,3,7, 8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage
    • Park J., Shigenaga M., and Ames B. Induction of cytochrome P4501A1 by 2,3,7, 8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage. Proc Natl Acad Sci USA 93 (1996) 2322-2327
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2322-2327
    • Park, J.1    Shigenaga, M.2    Ames, B.3
  • 248
    • 0033844631 scopus 로고    scopus 로고
    • Role of reactive oxygen intermediates in the decrease of hepatic cytochrome P450 activity by serum of humans and rabbits with an acute inflammatory reaction
    • El-Kadi A., Bleau A., Dumont I., Maurice H., and du Souich P. Role of reactive oxygen intermediates in the decrease of hepatic cytochrome P450 activity by serum of humans and rabbits with an acute inflammatory reaction. Drug Metab Dispos 28 (2000) 1112-1120
    • (2000) Drug Metab Dispos , vol.28 , pp. 1112-1120
    • El-Kadi, A.1    Bleau, A.2    Dumont, I.3    Maurice, H.4    du Souich, P.5
  • 249
    • 0034176077 scopus 로고    scopus 로고
    • New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
    • Campbell W. New role for epoxyeicosatrienoic acids as anti-inflammatory mediators. Trends Pharmacol Sci 21 (2000) 125-127
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 125-127
    • Campbell, W.1
  • 250
    • 0033870439 scopus 로고    scopus 로고
    • Nifedipine increases cytochrome P4502C expression and endothelium-derived hyperpolarizing factor-mediated responses in coronary arteries
    • Fisslthaler B., Hinsch N., Chataigneau T., Popp R., Kiss L., Busse R., et al. Nifedipine increases cytochrome P4502C expression and endothelium-derived hyperpolarizing factor-mediated responses in coronary arteries. Hypertension 36 (2000) 270-275
    • (2000) Hypertension , vol.36 , pp. 270-275
    • Fisslthaler, B.1    Hinsch, N.2    Chataigneau, T.3    Popp, R.4    Kiss, L.5    Busse, R.6
  • 251
    • 0033551176 scopus 로고    scopus 로고
    • Proinflammatory mediators chronically downregulate the formation of the endothelium-derived hyperpolarizing factor in arteries via a nitric oxide/cyclic GMP-dependent mechanism
    • Kessler P., Popp R., Busse R., and Schini-Kerth V. Proinflammatory mediators chronically downregulate the formation of the endothelium-derived hyperpolarizing factor in arteries via a nitric oxide/cyclic GMP-dependent mechanism. Circulation 99 (1999) 1878-1884
    • (1999) Circulation , vol.99 , pp. 1878-1884
    • Kessler, P.1    Popp, R.2    Busse, R.3    Schini-Kerth, V.4
  • 253
    • 0027320848 scopus 로고
    • ω-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s
    • ω-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s. Biochem Biophys Res Commun 192 (1993) 53-60
    • (1993) Biochem Biophys Res Commun , vol.192 , pp. 53-60
    • Renaud, J.1    Boucher, J.2    Vadon, S.3    Delaforge, M.4    Mansuy, D.5
  • 254
    • 0028809055 scopus 로고
    • The upregulating effect of dexamethasone on tumor necrosis factor production is mediated by a nitric oxide-producing cytochrome P450
    • Fantuzzi G., Galli G., Zinetti M., Fratelli M., and Ghezzi P. The upregulating effect of dexamethasone on tumor necrosis factor production is mediated by a nitric oxide-producing cytochrome P450. Cell Immunol 160 (1995) 305-308
    • (1995) Cell Immunol , vol.160 , pp. 305-308
    • Fantuzzi, G.1    Galli, G.2    Zinetti, M.3    Fratelli, M.4    Ghezzi, P.5
  • 255
    • 0029117980 scopus 로고
    • Cytochrome P450IIIA activity and cytokine-mediated synthesis of nitric oxide
    • Kuo P., Abe K., and Dafoe D. Cytochrome P450IIIA activity and cytokine-mediated synthesis of nitric oxide. Surgery 118 (1995) 310-317
    • (1995) Surgery , vol.118 , pp. 310-317
    • Kuo, P.1    Abe, K.2    Dafoe, D.3
  • 256
    • 0027519938 scopus 로고
    • Inhibitors of cytochrome P450 suppress tumor necrosis factor production
    • Fantuzzi G., Cantoni L., Sironi M., and Ghezzi P. Inhibitors of cytochrome P450 suppress tumor necrosis factor production. Cell Immunol 150 (1993) 417-424
    • (1993) Cell Immunol , vol.150 , pp. 417-424
    • Fantuzzi, G.1    Cantoni, L.2    Sironi, M.3    Ghezzi, P.4
  • 257
    • 0029865859 scopus 로고    scopus 로고
    • Role of nitric oxide in the cytokine-mediated regulation of cytochrome P-450
    • Carlson T., and Billings R. Role of nitric oxide in the cytokine-mediated regulation of cytochrome P-450. Mol Pharmacol 49 (1996) 796-801
    • (1996) Mol Pharmacol , vol.49 , pp. 796-801
    • Carlson, T.1    Billings, R.2
  • 258
    • 0031557144 scopus 로고    scopus 로고
    • Evidence for nitric oxide participation in down-regulation of CYP2B1/2 gene expression at the pretranslational level
    • Khatsenko O., Boobis A., and Gross S. Evidence for nitric oxide participation in down-regulation of CYP2B1/2 gene expression at the pretranslational level. Toxicol Lett 90 (1997) 207-216
    • (1997) Toxicol Lett , vol.90 , pp. 207-216
    • Khatsenko, O.1    Boobis, A.2    Gross, S.3
  • 259
    • 0031670445 scopus 로고    scopus 로고
    • Peroxynitrite-mediated nitration of tyrosine and inactivation of the catalytic activity of cytochrome P450 2B1
    • Roberts E., Lin H., Crowley J., Vuletich J., Osawa Y., and Hollenberg P. Peroxynitrite-mediated nitration of tyrosine and inactivation of the catalytic activity of cytochrome P450 2B1. Chem Res Toxicol 11 (1998) 1067-1074
    • (1998) Chem Res Toxicol , vol.11 , pp. 1067-1074
    • Roberts, E.1    Lin, H.2    Crowley, J.3    Vuletich, J.4    Osawa, Y.5    Hollenberg, P.6
  • 260
    • 0032804802 scopus 로고    scopus 로고
    • Endotoxin stimulates hepatocyte interleukin-6 production
    • Panesar N., Tolman K., and Mazuski J. Endotoxin stimulates hepatocyte interleukin-6 production. J Surg Res 85 (1999) 251-258
    • (1999) J Surg Res , vol.85 , pp. 251-258
    • Panesar, N.1    Tolman, K.2    Mazuski, J.3
  • 261
    • 0030853767 scopus 로고    scopus 로고
    • Nitric oxide-independent suppression of P450 2C11 expression by interleukin-1beta and endotoxin in primary rat hepatocytes
    • Sewer M., and Morgan E. Nitric oxide-independent suppression of P450 2C11 expression by interleukin-1beta and endotoxin in primary rat hepatocytes. Biochem Pharmacol 54 (1997) 729-737
    • (1997) Biochem Pharmacol , vol.54 , pp. 729-737
    • Sewer, M.1    Morgan, E.2
  • 262
    • 0032423246 scopus 로고    scopus 로고
    • Expression of CD14 by hepatocytes: Upregulation by cytokines during endotoxemia
    • Liu S., Khemlani L., Shapiro R., Johnson M., Liu K., Geller D., et al. Expression of CD14 by hepatocytes: Upregulation by cytokines during endotoxemia. Infect Immun 66 (1998) 5089-5098
    • (1998) Infect Immun , vol.66 , pp. 5089-5098
    • Liu, S.1    Khemlani, L.2    Shapiro, R.3    Johnson, M.4    Liu, K.5    Geller, D.6
  • 263
    • 0034234716 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent
    • Siewert E., Bort R., Kluge R., Heinrich P., Castell J., and Jover R. Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent. Hepatology 32 (2000) 49-55
    • (2000) Hepatology , vol.32 , pp. 49-55
    • Siewert, E.1    Bort, R.2    Kluge, R.3    Heinrich, P.4    Castell, J.5    Jover, R.6
  • 264
    • 0033047434 scopus 로고    scopus 로고
    • Kupffer cell-mediated differential down-regulation of cytochrome P450 metabolism in rat hepatocytes
    • Milosevic N., Schawalder H., and Maier P. Kupffer cell-mediated differential down-regulation of cytochrome P450 metabolism in rat hepatocytes. Eur J Pharmacol 368 (1999) 75-87
    • (1999) Eur J Pharmacol , vol.368 , pp. 75-87
    • Milosevic, N.1    Schawalder, H.2    Maier, P.3
  • 265
    • 0032927193 scopus 로고    scopus 로고
    • Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes
    • Tinel M., Elkahwaji J., Robin M., Fardel N., Descatoire V., Haouzi D., et al. Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes. J Pharmacol Exp Ther 289 (1999) 649-655
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 649-655
    • Tinel, M.1    Elkahwaji, J.2    Robin, M.3    Fardel, N.4    Descatoire, V.5    Haouzi, D.6
  • 266
    • 0026649510 scopus 로고
    • Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response
    • Alam T., An M., and Papaconstantinou J. Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response. J Biol Chem 267 (1992) 5021-5024
    • (1992) J Biol Chem , vol.267 , pp. 5021-5024
    • Alam, T.1    An, M.2    Papaconstantinou, J.3
  • 267
    • 0032540934 scopus 로고    scopus 로고
    • Re-expression of C/EBP alpha induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells
    • Jover R., Bort R., Gomez-Lechon M., and Castell J. Re-expression of C/EBP alpha induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells. FEBS Lett 431 (1998) 227-230
    • (1998) FEBS Lett , vol.431 , pp. 227-230
    • Jover, R.1    Bort, R.2    Gomez-Lechon, M.3    Castell, J.4
  • 268
    • 0027270555 scopus 로고
    • Response of human CYP1-luciferase plasmids to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons
    • Postlind H., Vu T., Tukey R., and Quattrochi L. Response of human CYP1-luciferase plasmids to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons. Toxicol Appl Pharmacol 118 (1993) 255-262
    • (1993) Toxicol Appl Pharmacol , vol.118 , pp. 255-262
    • Postlind, H.1    Vu, T.2    Tukey, R.3    Quattrochi, L.4
  • 269
    • 0037154405 scopus 로고    scopus 로고
    • Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450
    • Hodek P., Trefil P., and Stiborova M. Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450. Chem Biol Interact 139 (2002) 1-21
    • (2002) Chem Biol Interact , vol.139 , pp. 1-21
    • Hodek, P.1    Trefil, P.2    Stiborova, M.3
  • 270
    • 0642286442 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by some vegetable constituents determined using in vitro reporter gene assay
    • Amakura Y., Tsutsumi T., Nakamura M., Kitagawa H., Fujino J., Sasaki K., et al. Activation of the aryl hydrocarbon receptor by some vegetable constituents determined using in vitro reporter gene assay. Biol Pharm Bull 26 (2003) 232-239
    • (2003) Biol Pharm Bull , vol.26 , pp. 232-239
    • Amakura, Y.1    Tsutsumi, T.2    Nakamura, M.3    Kitagawa, H.4    Fujino, J.5    Sasaki, K.6
  • 271
    • 0036481911 scopus 로고    scopus 로고
    • Preliminary screening of the inhibitory effect of food extracts on activation of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Amakura Y., Tsutsumi T., Nakamura M., Kitagawa H., Fujino J., Sasaki K., et al. Preliminary screening of the inhibitory effect of food extracts on activation of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biol Pharm Bull 25 (2002) 272-274
    • (2002) Biol Pharm Bull , vol.25 , pp. 272-274
    • Amakura, Y.1    Tsutsumi, T.2    Nakamura, M.3    Kitagawa, H.4    Fujino, J.5    Sasaki, K.6
  • 272
    • 0041511846 scopus 로고    scopus 로고
    • Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits
    • Jeuken A., Keser B., Khan E., Brouwer A., Koeman J., and Denison M. Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. J Agric Food Chem 51 (2003) 5478-5487
    • (2003) J Agric Food Chem , vol.51 , pp. 5478-5487
    • Jeuken, A.1    Keser, B.2    Khan, E.3    Brouwer, A.4    Koeman, J.5    Denison, M.6
  • 273
    • 0036188407 scopus 로고    scopus 로고
    • St John's Wort supplements endanger the success of organ transplantation
    • Ernst E. St John's Wort supplements endanger the success of organ transplantation. Arch Surg 137 (2002) 316-319
    • (2002) Arch Surg , vol.137 , pp. 316-319
    • Ernst, E.1
  • 274
    • 0034620261 scopus 로고    scopus 로고
    • Herb-drug interactions
    • Fugh-Berman A. Herb-drug interactions. Lancet 355 (2000) 134-138
    • (2000) Lancet , vol.355 , pp. 134-138
    • Fugh-Berman, A.1
  • 275
    • 85015564429 scopus 로고    scopus 로고
    • Herbal supplements: Indications, clinical concerns, and safety
    • Fugh-Berman A. Herbal supplements: Indications, clinical concerns, and safety. Nutr Today 37 (2002) 122-124
    • (2002) Nutr Today , vol.37 , pp. 122-124
    • Fugh-Berman, A.1
  • 277
  • 278
  • 279
    • 20144376107 scopus 로고    scopus 로고
    • Induction of drug metabolizing enzymes by vitamin E
    • Brigelius-Flohe R. Induction of drug metabolizing enzymes by vitamin E. J Plant Physiol 162 (2005) 797-802
    • (2005) J Plant Physiol , vol.162 , pp. 797-802
    • Brigelius-Flohe, R.1
  • 281
    • 0242645646 scopus 로고    scopus 로고
    • Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin
    • Lilja J., Kivisto K., and Neuvonen P. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 66 (1999) 118-127
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 118-127
    • Lilja, J.1    Kivisto, K.2    Neuvonen, P.3
  • 282
    • 0033736174 scopus 로고    scopus 로고
    • Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin
    • Lilja J., Kivisto K., and Neuvonen P. Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin. Clin Pharmacol Ther 68 (2000) 384-390
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 384-390
    • Lilja, J.1    Kivisto, K.2    Neuvonen, P.3
  • 283
    • 3142523464 scopus 로고    scopus 로고
    • Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin
    • Lilja J., Neuvonen M., and Neuvonen P. Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin. Br J Clin Pharmacol 58 (2004) 56-60
    • (2004) Br J Clin Pharmacol , vol.58 , pp. 56-60
    • Lilja, J.1    Neuvonen, M.2    Neuvonen, P.3
  • 284
    • 7244224993 scopus 로고    scopus 로고
    • Interactions between grapefruit juice and cardiovascular drugs
    • Bailey D., and Dresser G. Interactions between grapefruit juice and cardiovascular drugs. Am J Cardiovasc Drugs 4 (2004) 281-297
    • (2004) Am J Cardiovasc Drugs , vol.4 , pp. 281-297
    • Bailey, D.1    Dresser, G.2
  • 285
    • 0032806042 scopus 로고    scopus 로고
    • Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent
    • Barclay T., Peters J., Sewer M., Ferrari L., Gonzalez F., and Morgan E. Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent. J Pharmacol Exp Ther 290 (1999) 1250-1257
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1250-1257
    • Barclay, T.1    Peters, J.2    Sewer, M.3    Ferrari, L.4    Gonzalez, F.5    Morgan, E.6
  • 286
    • 0025305212 scopus 로고
    • Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation
    • Imaoka S., Terano Y., and Funae Y. Changes in the amount of cytochrome P450s in rat hepatic microsomes with starvation. Arch Biochem Biophys 278 (1990) 168-178
    • (1990) Arch Biochem Biophys , vol.278 , pp. 168-178
    • Imaoka, S.1    Terano, Y.2    Funae, Y.3
  • 287
    • 0035153584 scopus 로고    scopus 로고
    • Characterization of CYP4A induction in rat liver by inflammatory stimuli: Dependence on sex, strain, and inflammation-evoked hypophagia
    • Mitchell S., Sewer M., Kardar S., and Morgan E. Characterization of CYP4A induction in rat liver by inflammatory stimuli: Dependence on sex, strain, and inflammation-evoked hypophagia. Drug Metab Dispos 29 (2001) 17-22
    • (2001) Drug Metab Dispos , vol.29 , pp. 17-22
    • Mitchell, S.1    Sewer, M.2    Kardar, S.3    Morgan, E.4
  • 288
    • 0031871085 scopus 로고    scopus 로고
    • Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene
    • Sewer M., Barclay T., and Morgan E. Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene. Mol Pharmacol 54 (1998) 273-279
    • (1998) Mol Pharmacol , vol.54 , pp. 273-279
    • Sewer, M.1    Barclay, T.2    Morgan, E.3
  • 289
    • 0031963540 scopus 로고    scopus 로고
    • Expression and distribution of cytochrome P450 enzymes in male rat kidney: Effects of ethanol, acetone and dietary conditions
    • Ronis M., Huang J., Longo V., Tindberg N., Ingelman-Sundberg M., and Badger T. Expression and distribution of cytochrome P450 enzymes in male rat kidney: Effects of ethanol, acetone and dietary conditions. Biochem Pharmacol 55 (1998) 123-129
    • (1998) Biochem Pharmacol , vol.55 , pp. 123-129
    • Ronis, M.1    Huang, J.2    Longo, V.3    Tindberg, N.4    Ingelman-Sundberg, M.5    Badger, T.6
  • 290
    • 0037369729 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis
    • Chalasani N., Gorski J., Asghar M., Asghar A., Foresman B., Hall S., et al. Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis. Hepatology 37 (2003) 544-550
    • (2003) Hepatology , vol.37 , pp. 544-550
    • Chalasani, N.1    Gorski, J.2    Asghar, M.3    Asghar, A.4    Foresman, B.5    Hall, S.6
  • 291
    • 0041764982 scopus 로고    scopus 로고
    • CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
    • Emery M., Fisher J., Chien J., Kharasch E., Dellinger E., Kowdley K., et al. CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease. Hepatology 38 (2003) 428-435
    • (2003) Hepatology , vol.38 , pp. 428-435
    • Emery, M.1    Fisher, J.2    Chien, J.3    Kharasch, E.4    Dellinger, E.5    Kowdley, K.6
  • 292
    • 0032437172 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation
    • Lucas D., Farez C., Bardou L., Vaisse J., Attali J., and Valensi P. Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation. Fundam Clin Pharmacol 12 (1998) 553-558
    • (1998) Fundam Clin Pharmacol , vol.12 , pp. 553-558
    • Lucas, D.1    Farez, C.2    Bardou, L.3    Vaisse, J.4    Attali, J.5    Valensi, P.6
  • 293
    • 0037241174 scopus 로고    scopus 로고
    • Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans
    • Wang Z., Hall S., Maya J., Li L., Asghar A., and Gorski J. Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans. Br J Clin Pharmacol 55 (2003) 77-85
    • (2003) Br J Clin Pharmacol , vol.55 , pp. 77-85
    • Wang, Z.1    Hall, S.2    Maya, J.3    Li, L.4    Asghar, A.5    Gorski, J.6
  • 294
    • 23344450788 scopus 로고    scopus 로고
    • Induction of phase I, II and III drug metabolism/transport by xenobiotics
    • Xu C., Li C., and Kong A. Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch Pharm Res 28 (2005) 249-268
    • (2005) Arch Pharm Res , vol.28 , pp. 249-268
    • Xu, C.1    Li, C.2    Kong, A.3
  • 295
    • 0035872478 scopus 로고    scopus 로고
    • Differential regulation of cytochrome P450 1A1 and 1B1 by a combination of dioxin and pesticides in the breast tumor cell line MCF-7
    • Coumoul X., Diry M., Robillot C., and Barouki R. Differential regulation of cytochrome P450 1A1 and 1B1 by a combination of dioxin and pesticides in the breast tumor cell line MCF-7. Cancer Res 61 (2001) 3942-3948
    • (2001) Cancer Res , vol.61 , pp. 3942-3948
    • Coumoul, X.1    Diry, M.2    Robillot, C.3    Barouki, R.4
  • 296
    • 0042343720 scopus 로고    scopus 로고
    • The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor
    • Wyde M., Bartolucci E., Ueda A., Zhang H., Yan B., Negishi M., et al. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor. Mol Pharmacol 64 (2003) 474-481
    • (2003) Mol Pharmacol , vol.64 , pp. 474-481
    • Wyde, M.1    Bartolucci, E.2    Ueda, A.3    Zhang, H.4    Yan, B.5    Negishi, M.6
  • 297
    • 0642307415 scopus 로고    scopus 로고
    • Potential role of statins in inflammation and atherosclerosis
    • Yoshida M. Potential role of statins in inflammation and atherosclerosis. J Atheroscler Thromb 10 (2003) 140-144
    • (2003) J Atheroscler Thromb , vol.10 , pp. 140-144
    • Yoshida, M.1
  • 298
    • 22544481127 scopus 로고    scopus 로고
    • Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8
    • Tornio A., Pasanen M., Laitila J., Neuvonen P., and Backman J. Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8. Basic Clin Pharmacol Toxicol 97 (2005) 104-108
    • (2005) Basic Clin Pharmacol Toxicol , vol.97 , pp. 104-108
    • Tornio, A.1    Pasanen, M.2    Laitila, J.3    Neuvonen, P.4    Backman, J.5
  • 299
    • 20444503924 scopus 로고    scopus 로고
    • Interaction between amlodipine and simvastatin in patients with hypercholesterolemia and hypertension
    • Nishio S., Watanabe H., Kosuge K., Uchida S., Hayashi H., and Ohashi K. Interaction between amlodipine and simvastatin in patients with hypercholesterolemia and hypertension. Hypertens Res 28 (2005) 223-227
    • (2005) Hypertens Res , vol.28 , pp. 223-227
    • Nishio, S.1    Watanabe, H.2    Kosuge, K.3    Uchida, S.4    Hayashi, H.5    Ohashi, K.6
  • 300
    • 1142274350 scopus 로고    scopus 로고
    • Oral anticoagulant drug interactions with statins: Case report of fluvastatin and review of the literature
    • Andrus M. Oral anticoagulant drug interactions with statins: Case report of fluvastatin and review of the literature. Pharmacotherapy 24 (2004) 285-290
    • (2004) Pharmacotherapy , vol.24 , pp. 285-290
    • Andrus, M.1
  • 301
    • 0942300658 scopus 로고    scopus 로고
    • Rosuvastatin-warfarin drug interaction
    • Barry M. Rosuvastatin-warfarin drug interaction. Lancet 363 (2004) 328
    • (2004) Lancet , vol.363 , pp. 328
    • Barry, M.1
  • 302
    • 0030784620 scopus 로고    scopus 로고
    • Atorvastatin does not alter the anticoagulant activity of warfarin
    • Stern R., Abel R., Gibson G., and Besserer J. Atorvastatin does not alter the anticoagulant activity of warfarin. J Clin Pharmacol 37 (1997) 1062-1064
    • (1997) J Clin Pharmacol , vol.37 , pp. 1062-1064
    • Stern, R.1    Abel, R.2    Gibson, G.3    Besserer, J.4
  • 303
    • 31344464596 scopus 로고    scopus 로고
    • Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity
    • Caro A., and Cederbaum A. Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity. Free Radic Biol Med 40 (2006) 364-375
    • (2006) Free Radic Biol Med , vol.40 , pp. 364-375
    • Caro, A.1    Cederbaum, A.2
  • 304
    • 0031944635 scopus 로고    scopus 로고
    • + channels and contraction in mammalian heart cells
    • + channels and contraction in mammalian heart cells. J Physiol 508 (1998) 777-792
    • (1998) J Physiol , vol.508 , pp. 777-792
    • Xiao, Y.1    Huang, L.2    Morgan, J.3
  • 305
    • 18344400259 scopus 로고    scopus 로고
    • Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases
    • Capdevila J., and Falck J. Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases. Prostaglandins Other Lipid Mediat 68-69 (2002) 325-344
    • (2002) Prostaglandins Other Lipid Mediat , vol.68-69 , pp. 325-344
    • Capdevila, J.1    Falck, J.2
  • 306
    • 0037980428 scopus 로고    scopus 로고
    • The CYP P450 arachidonate monooxygenases: Enzymatic relays for the control of kidney function and blood pressure
    • Capdevila J., Nakagawa K., and Holla V. The CYP P450 arachidonate monooxygenases: Enzymatic relays for the control of kidney function and blood pressure. Adv Exp Med Biol 525 (2003) 39-46
    • (2003) Adv Exp Med Biol , vol.525 , pp. 39-46
    • Capdevila, J.1    Nakagawa, K.2    Holla, V.3
  • 307
    • 0030297422 scopus 로고    scopus 로고
    • Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes
    • Powell P., Wolf I., and Lasker J. Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes. Arch Biochem Biophys 335 (1996) 219-226
    • (1996) Arch Biochem Biophys , vol.335 , pp. 219-226
    • Powell, P.1    Wolf, I.2    Lasker, J.3
  • 308
    • 1542722060 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenases as EDHF synthase(s)
    • Fleming I. Cytochrome P450 epoxygenases as EDHF synthase(s). Pharmacol Res 49 (2004) 525-533
    • (2004) Pharmacol Res , vol.49 , pp. 525-533
    • Fleming, I.1
  • 309
    • 27544449950 scopus 로고    scopus 로고
    • Omega oxygenases: Nonheme-iron enzymes and P450 cytochromes
    • Coon M. Omega oxygenases: Nonheme-iron enzymes and P450 cytochromes. Biochem Biophys Res Commun 338 (2005) 378-385
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 378-385
    • Coon, M.1
  • 310
    • 0034711488 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids
    • Yu Z., Xu F., Huse L., Morisseau C., Draper A., Newman J., et al. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res 87 (2000) 992-998
    • (2000) Circ Res , vol.87 , pp. 992-998
    • Yu, Z.1    Xu, F.2    Huse, L.3    Morisseau, C.4    Draper, A.5    Newman, J.6
  • 311
    • 0030051805 scopus 로고    scopus 로고
    • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
    • Campbell W., Gebremedhin D., Pratt P., and Harder D. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res 78 (1996) 415-423
    • (1996) Circ Res , vol.78 , pp. 415-423
    • Campbell, W.1    Gebremedhin, D.2    Pratt, P.3    Harder, D.4
  • 313
    • 9644279413 scopus 로고    scopus 로고
    • Cytochrome P450 omega-hydroxylase inhibition reduces infarct size during reperfusion via the sarcolemmal KATP channel
    • Gross E., Nithipatikom K., Hsu A., Peart J., Falck J., Campbell W., et al. Cytochrome P450 omega-hydroxylase inhibition reduces infarct size during reperfusion via the sarcolemmal KATP channel. J Mol Cell Cardiol 37 (2004) 1245-1249
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 1245-1249
    • Gross, E.1    Nithipatikom, K.2    Hsu, A.3    Peart, J.4    Falck, J.5    Campbell, W.6
  • 314
    • 0035893696 scopus 로고    scopus 로고
    • + channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes
    • + channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes. J Physiol 537 (2001) 811-827
    • (2001) J Physiol , vol.537 , pp. 811-827
    • Lu, T.1    Hoshi, T.2    Weintraub, N.3    Spector, A.4    Lee, H.5
  • 315
    • 0032478779 scopus 로고    scopus 로고
    • 11,12-Epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells
    • Hoebel B., and Graier W. 11,12-Epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells. Eur J Pharmacol 346 (1998) 115-117
    • (1998) Eur J Pharmacol , vol.346 , pp. 115-117
    • Hoebel, B.1    Graier, W.2
  • 316
    • 0242720683 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids (EETs): Metabolism and biochemical function
    • Spector A., Fang X., Snyder G., and Weintraub N. Epoxyeicosatrienoic acids (EETs): Metabolism and biochemical function. Prog Lipid Res 43 (2004) 55-90
    • (2004) Prog Lipid Res , vol.43 , pp. 55-90
    • Spector, A.1    Fang, X.2    Snyder, G.3    Weintraub, N.4
  • 317
    • 0035167421 scopus 로고    scopus 로고
    • Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid
    • Fukao M., Mason H., Kenyon J., Horowitz B., and Keef K. Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid. Mol Pharmacol 59 (2001) 16-23
    • (2001) Mol Pharmacol , vol.59 , pp. 16-23
    • Fukao, M.1    Mason, H.2    Kenyon, J.3    Horowitz, B.4    Keef, K.5
  • 318
    • 16244392787 scopus 로고    scopus 로고
    • Potassium channels in the peripheral microcirculation
    • Jackson W. Potassium channels in the peripheral microcirculation. Microcirculation 12 (2005) 113-127
    • (2005) Microcirculation , vol.12 , pp. 113-127
    • Jackson, W.1
  • 319
    • 33644815636 scopus 로고    scopus 로고
    • Regulation of potassium channels in coronary smooth muscle by adenoviral expression of cytochrome P-450 epoxygenase
    • Campbell W., Holmes B., Falck J., Capdevila J., and Gauthier K. Regulation of potassium channels in coronary smooth muscle by adenoviral expression of cytochrome P-450 epoxygenase. Am J Physiol Heart Circ Physiol 290 (2006) H64-H71
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Campbell, W.1    Holmes, B.2    Falck, J.3    Capdevila, J.4    Gauthier, K.5
  • 320
    • 1542343991 scopus 로고    scopus 로고
    • Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids
    • Krotz F., Riexinger T., Buerkle M., Nithipatikom K., Gloe T., Sohn H., et al. Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. Arterioscler Thromb Vasc Biol 24 (2004) 595-600
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 595-600
    • Krotz, F.1    Riexinger, T.2    Buerkle, M.3    Nithipatikom, K.4    Gloe, T.5    Sohn, H.6
  • 322
    • 0034923447 scopus 로고    scopus 로고
    • Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells
    • Yang B., Graham L., Dikalov S., Mason R., Falck J., Liao J., et al. Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol 60 (2001) 310-320
    • (2001) Mol Pharmacol , vol.60 , pp. 310-320
    • Yang, B.1    Graham, L.2    Dikalov, S.3    Mason, R.4    Falck, J.5    Liao, J.6
  • 323
    • 0035910620 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries
    • Fleming I., Michaelis U., Bredenkotter D., Fisslthaler B., Dehghani F., Brandes R., et al. Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. Circ Res 88 (2001) 44-51
    • (2001) Circ Res , vol.88 , pp. 44-51
    • Fleming, I.1    Michaelis, U.2    Bredenkotter, D.3    Fisslthaler, B.4    Dehghani, F.5    Brandes, R.6
  • 324
    • 13244251341 scopus 로고    scopus 로고
    • Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce the expression of cyclooxygenase-2 in endothelial cells
    • Michaelis U., Falck J., Schmidt R., Busse R., and Fleming I. Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce the expression of cyclooxygenase-2 in endothelial cells. Arterioscler Thromb Vasc Biol 25 (2005) 321-326
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 321-326
    • Michaelis, U.1    Falck, J.2    Schmidt, R.3    Busse, R.4    Fleming, I.5
  • 325
    • 0035138432 scopus 로고    scopus 로고
    • Cytochrome P450 metabolites of arachidonic acid in the control of renal function
    • Maier K., and Roman R. Cytochrome P450 metabolites of arachidonic acid in the control of renal function. Curr Opin Nephrol Hypertens 10 (2001) 81-87
    • (2001) Curr Opin Nephrol Hypertens , vol.10 , pp. 81-87
    • Maier, K.1    Roman, R.2
  • 326
    • 0031593394 scopus 로고    scopus 로고
    • Renal functional effects of endothelins: Dependency on cytochrome P450-derived arachidonate metabolites
    • Oyekan A., McAward K., and McGiff J. Renal functional effects of endothelins: Dependency on cytochrome P450-derived arachidonate metabolites. Biol Res 31 (1998) 209-215
    • (1998) Biol Res , vol.31 , pp. 209-215
    • Oyekan, A.1    McAward, K.2    McGiff, J.3
  • 327
    • 0031731451 scopus 로고    scopus 로고
    • Functional response of the rat kidney to inhibition of nitric oxide synthesis: Role of cytochrome p450-derived arachidonate metabolites
    • Oyekan A., and McGiff J. Functional response of the rat kidney to inhibition of nitric oxide synthesis: Role of cytochrome p450-derived arachidonate metabolites. Br J Pharmacol 125 (1998) 1065-1073
    • (1998) Br J Pharmacol , vol.125 , pp. 1065-1073
    • Oyekan, A.1    McGiff, J.2
  • 329
    • 0035104516 scopus 로고    scopus 로고
    • 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure
    • McGiff J., and Quilley J. 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure. Curr Opin Nephrol Hypertens 10 (2001) 231-237
    • (2001) Curr Opin Nephrol Hypertens , vol.10 , pp. 231-237
    • McGiff, J.1    Quilley, J.2
  • 330
    • 0034534288 scopus 로고    scopus 로고
    • Eicosanoid regulation of the renal vasculature
    • Imig J. Eicosanoid regulation of the renal vasculature. Am J Physiol Renal Physiol 279 (2000) F965-F981
    • (2000) Am J Physiol Renal Physiol , vol.279
    • Imig, J.1
  • 331
    • 0037404487 scopus 로고    scopus 로고
    • CYP4A metabolites of arachidonic acid and VEGF are mediators of skeletal muscle angiogenesis
    • Amaral S., Maier K., Schippers D., Roman R., and Greene A. CYP4A metabolites of arachidonic acid and VEGF are mediators of skeletal muscle angiogenesis. Am J Physiol Heart Circ Physiol 284 (2003) H1528-H1535
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Amaral, S.1    Maier, K.2    Schippers, D.3    Roman, R.4    Greene, A.5
  • 332
    • 13844309746 scopus 로고    scopus 로고
    • Regulation and inhibition of arachidonic acid omega-hydroxylases and 20-HETE formation
    • Kroetz D., and Xu F. Regulation and inhibition of arachidonic acid omega-hydroxylases and 20-HETE formation. Annu Rev Pharmacol Toxicol 45 (2005) 413-438
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 413-438
    • Kroetz, D.1    Xu, F.2
  • 333
    • 2942566186 scopus 로고    scopus 로고
    • Role of cytochrome P450 metabolites of arachidonic acid in hypertension
    • Sarkis A., and Roman R. Role of cytochrome P450 metabolites of arachidonic acid in hypertension. Curr Drug Metab 5 (2004) 245-256
    • (2004) Curr Drug Metab , vol.5 , pp. 245-256
    • Sarkis, A.1    Roman, R.2
  • 334
    • 0031002404 scopus 로고    scopus 로고
    • Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue
    • Harder D., Lange A., Gebremedhin D., Birks E., and Roman R. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J Vasc Res 34 (1997) 237-243
    • (1997) J Vasc Res , vol.34 , pp. 237-243
    • Harder, D.1    Lange, A.2    Gebremedhin, D.3    Birks, E.4    Roman, R.5
  • 335
    • 13244270236 scopus 로고    scopus 로고
    • P450 in the angiogenesis affair: The unusual suspect
    • Ljubimov A., and Grant M. P450 in the angiogenesis affair: The unusual suspect. Am J Pathol 166 (2005) 341-344
    • (2005) Am J Pathol , vol.166 , pp. 341-344
    • Ljubimov, A.1    Grant, M.2
  • 336
    • 13244257651 scopus 로고    scopus 로고
    • Mechanisms regulating cerebral blood flow as therapeutic targets
    • Pratt P., Medhora M., and Harder D. Mechanisms regulating cerebral blood flow as therapeutic targets. Curr Opin Investig Drugs 5 (2004) 952-956
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 952-956
    • Pratt, P.1    Medhora, M.2    Harder, D.3
  • 337
    • 3042640898 scopus 로고    scopus 로고
    • Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology
    • Sacerdoti D., Gatta A., and McGiff J. Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology. Prostaglandins Other Lipid Mediat 72 (2003) 51-71
    • (2003) Prostaglandins Other Lipid Mediat , vol.72 , pp. 51-71
    • Sacerdoti, D.1    Gatta, A.2    McGiff, J.3
  • 338
    • 0037302804 scopus 로고    scopus 로고
    • Kidney CYP450 enzymes: Biological actions beyond drug metabolism
    • Zhao X., and Imig J. Kidney CYP450 enzymes: Biological actions beyond drug metabolism. Curr Drug Metab 4 (2003) 73-84
    • (2003) Curr Drug Metab , vol.4 , pp. 73-84
    • Zhao, X.1    Imig, J.2
  • 339
    • 0027956790 scopus 로고
    • Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species
    • Bondy S., and Naderi S. Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species. Biochem Pharmacol 48 (1994) 155-159
    • (1994) Biochem Pharmacol , vol.48 , pp. 155-159
    • Bondy, S.1    Naderi, S.2
  • 340
    • 0032077936 scopus 로고    scopus 로고
    • Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes
    • Puntarulo S., and Cederbaum A. Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes. Free Radic Biol Med 24 (1998) 1324-1330
    • (1998) Free Radic Biol Med , vol.24 , pp. 1324-1330
    • Puntarulo, S.1    Cederbaum, A.2
  • 341
    • 0032403179 scopus 로고    scopus 로고
    • Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography-mass spectrometry with ion trap MS
    • Bylund J., Ericsson J., and Oliw E. Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography-mass spectrometry with ion trap MS. Anal Biochem 265 (1998) 55-68
    • (1998) Anal Biochem , vol.265 , pp. 55-68
    • Bylund, J.1    Ericsson, J.2    Oliw, E.3
  • 342
    • 0034329515 scopus 로고    scopus 로고
    • Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s
    • Moran J., Mitchell L., Bradbury J., Qu W., Zeldin D., Schnellmann R., et al. Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s. Toxicol Appl Pharmacol 168 (2000) 268-279
    • (2000) Toxicol Appl Pharmacol , vol.168 , pp. 268-279
    • Moran, J.1    Mitchell, L.2    Bradbury, J.3    Qu, W.4    Zeldin, D.5    Schnellmann, R.6
  • 343
  • 344
    • 0346887196 scopus 로고    scopus 로고
    • Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells
    • Viswanathan S., Hammock B., Newman J., Meerarani P., Toborek M., and Hennig B. Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. J Am Coll Nutr 22 (2003) 502-510
    • (2003) J Am Coll Nutr , vol.22 , pp. 502-510
    • Viswanathan, S.1    Hammock, B.2    Newman, J.3    Meerarani, P.4    Toborek, M.5    Hennig, B.6
  • 345
    • 0035869413 scopus 로고    scopus 로고
    • The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells
    • Slim R., Hammock B., Toborek M., Robertson L., Newman J., Morisseau C., et al. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. Toxicol Appl Pharmacol 171 (2001) 184-193
    • (2001) Toxicol Appl Pharmacol , vol.171 , pp. 184-193
    • Slim, R.1    Hammock, B.2    Toborek, M.3    Robertson, L.4    Newman, J.5    Morisseau, C.6
  • 346
    • 0032248101 scopus 로고    scopus 로고
    • The role of linoleic acid in endothelial cell gene expression. Relationship to atherosclerosis
    • Toborek M., and Hennig B. The role of linoleic acid in endothelial cell gene expression. Relationship to atherosclerosis. Subcell Biochem 30 (1998) 415-436
    • (1998) Subcell Biochem , vol.30 , pp. 415-436
    • Toborek, M.1    Hennig, B.2
  • 347
    • 0034058249 scopus 로고    scopus 로고
    • Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney
    • Yu Z., Huse L., Adler P., Graham L., Ma J., Zeldin D., et al. Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney. Mol Pharmacol 57 (2000) 1011-1120
    • (2000) Mol Pharmacol , vol.57 , pp. 1011-1120
    • Yu, Z.1    Huse, L.2    Adler, P.3    Graham, L.4    Ma, J.5    Zeldin, D.6
  • 348
    • 0034097023 scopus 로고    scopus 로고
    • Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension
    • Frisbee J., Falck J., and Lombard J. Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension. Am J Physiol Heart Circ Physiol 278 (2000) H1517-H1526
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Frisbee, J.1    Falck, J.2    Lombard, J.3
  • 349
    • 0030755144 scopus 로고    scopus 로고
    • Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney
    • Kroetz D., Huse L., Thuresson A., and Grillo M. Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney. Mol Pharmacol 52 (1997) 362-372
    • (1997) Mol Pharmacol , vol.52 , pp. 362-372
    • Kroetz, D.1    Huse, L.2    Thuresson, A.3    Grillo, M.4
  • 350
    • 0035104648 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acid-mediated renal vasodilation to arachidonic acid is enhanced in SHR
    • Pomposiello S., Carroll M., Falck J., and McGiff J. Epoxyeicosatrienoic acid-mediated renal vasodilation to arachidonic acid is enhanced in SHR. Hypertension 37 (2001) 887-893
    • (2001) Hypertension , vol.37 , pp. 887-893
    • Pomposiello, S.1    Carroll, M.2    Falck, J.3    McGiff, J.4
  • 351
    • 0034992133 scopus 로고    scopus 로고
    • Abnormal pressure-natriuresis in hypertension: Role of cytochrome P450 metabolites of arachidonic acid
    • Moreno C., Maier K., Hoagland K., Yu M., and Roman R. Abnormal pressure-natriuresis in hypertension: Role of cytochrome P450 metabolites of arachidonic acid. Am J Hypertens 14 (2001) 90S-97S
    • (2001) Am J Hypertens , vol.14
    • Moreno, C.1    Maier, K.2    Hoagland, K.3    Yu, M.4    Roman, R.5
  • 352
    • 0032725975 scopus 로고    scopus 로고
    • The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading
    • Holla V., Makita K., Capdevila J., and Zaphiropoulos P. The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading. J Clin Investig 104 (1999) 751-760
    • (1999) J Clin Investig , vol.104 , pp. 751-760
    • Holla, V.1    Makita, K.2    Capdevila, J.3    Zaphiropoulos, P.4
  • 353
    • 22344451528 scopus 로고    scopus 로고
    • Exaggerated response to adenosine in kidneys from high salt-fed rats: Role of epoxyeicosatrienoic acids
    • Liclican E., McGiff J., Pedraza P., Ferreri N., Falck J., and Carroll M. Exaggerated response to adenosine in kidneys from high salt-fed rats: Role of epoxyeicosatrienoic acids. Am J Physiol Renal Physiol 289 (2005) F386-F392
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Liclican, E.1    McGiff, J.2    Pedraza, P.3    Ferreri, N.4    Falck, J.5    Carroll, M.6
  • 354
    • 20444494404 scopus 로고    scopus 로고
    • Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia
    • Taniguchi J., Honda H., Shibusawa Y., Iwata T., and Notoya Y. Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia. Vascul Pharmacol 43 (2005) 47-55
    • (2005) Vascul Pharmacol , vol.43 , pp. 47-55
    • Taniguchi, J.1    Honda, H.2    Shibusawa, Y.3    Iwata, T.4    Notoya, Y.5
  • 355
    • 0033779422 scopus 로고    scopus 로고
    • Cytochrome P450 activity and endothelial dysfunction in insulin resistance
    • Katakam P., Hoenig M., Ujhelyi M., and Miller A. Cytochrome P450 activity and endothelial dysfunction in insulin resistance. J Vasc Res 37 (2000) 426-434
    • (2000) J Vasc Res , vol.37 , pp. 426-434
    • Katakam, P.1    Hoenig, M.2    Ujhelyi, M.3    Miller, A.4
  • 356
    • 0026485504 scopus 로고
    • Tobacco and myocardial infarction: Is snuff less dangerous than cigarettes?
    • Huhtasaari F., Asplund K., Lundberg V., Stegmayr B., and Wester P. Tobacco and myocardial infarction: Is snuff less dangerous than cigarettes?. BMJ 305 (1992) 1252-1256
    • (1992) BMJ , vol.305 , pp. 1252-1256
    • Huhtasaari, F.1    Asplund, K.2    Lundberg, V.3    Stegmayr, B.4    Wester, P.5
  • 357
    • 0033571196 scopus 로고    scopus 로고
    • Smokeless tobacco as a possible risk factor for myocardial infarction: A population-based study in middle-aged men
    • Huhtasaari F., Lundberg V., Eliasson M., Janlert U., and Asplund K. Smokeless tobacco as a possible risk factor for myocardial infarction: A population-based study in middle-aged men. J Am Coll Cardiol 34 (1999) 1784-1790
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1784-1790
    • Huhtasaari, F.1    Lundberg, V.2    Eliasson, M.3    Janlert, U.4    Asplund, K.5
  • 358
    • 2642619431 scopus 로고    scopus 로고
    • Nicotine replacement: A new approach to reducing tobacco-related harm
    • Jimenez-Ruiz C., Kunze M., and Fagerstrom K. Nicotine replacement: A new approach to reducing tobacco-related harm. Eur Respir J 11 (1998) 473-479
    • (1998) Eur Respir J , vol.11 , pp. 473-479
    • Jimenez-Ruiz, C.1    Kunze, M.2    Fagerstrom, K.3
  • 360
    • 0025780925 scopus 로고
    • Interactions between cultured bovine arterial endothelial and smooth muscle cells: Effects of injury on the release of growth stimulating and growth inhibiting substances
    • Xu C., Pessah-Rasmussen H., and Stavenow L. Interactions between cultured bovine arterial endothelial and smooth muscle cells: Effects of injury on the release of growth stimulating and growth inhibiting substances. Pharmacol Toxicol 69 (1991) 195-200
    • (1991) Pharmacol Toxicol , vol.69 , pp. 195-200
    • Xu, C.1    Pessah-Rasmussen, H.2    Stavenow, L.3
  • 361
    • 0028085436 scopus 로고
    • Interactions between cultured bovine arterial endothelial and smooth muscle cells; effects of modulated low density lipoproteins on cell proliferation and prostacyclin release
    • Xu C., Stavenow L., and Pessah-Rasmussen H. Interactions between cultured bovine arterial endothelial and smooth muscle cells; effects of modulated low density lipoproteins on cell proliferation and prostacyclin release. Scand J Clin Lab Invest 54 (1994) 191-198
    • (1994) Scand J Clin Lab Invest , vol.54 , pp. 191-198
    • Xu, C.1    Stavenow, L.2    Pessah-Rasmussen, H.3
  • 362
    • 33644763047 scopus 로고    scopus 로고
    • Lipid-soluble smoke particles damage endothelial cells and reduce endothelium-dependent dilatation in rat and man
    • Zhang J., Cao Y., Xu C., and Edvinsson L. Lipid-soluble smoke particles damage endothelial cells and reduce endothelium-dependent dilatation in rat and man. BMC Cardiovasc Disord 6 (2006) 3
    • (2006) BMC Cardiovasc Disord , vol.6 , pp. 3
    • Zhang, J.1    Cao, Y.2    Xu, C.3    Edvinsson, L.4
  • 363
    • 33645564268 scopus 로고    scopus 로고
    • Nicotine induces tissue factor expression in cultured endothelial and smooth muscle cells
    • Cirillo P., De Rosa S., Pacileo M., Gargiulo A., Leonardi A., Angri V., et al. Nicotine induces tissue factor expression in cultured endothelial and smooth muscle cells. J Thromb Haemost 4 (2006) 453-458
    • (2006) J Thromb Haemost , vol.4 , pp. 453-458
    • Cirillo, P.1    De Rosa, S.2    Pacileo, M.3    Gargiulo, A.4    Leonardi, A.5    Angri, V.6
  • 365
    • 0025033003 scopus 로고
    • Role of somatic mutation in atherosclerosis
    • Penn A. Role of somatic mutation in atherosclerosis. Prog Clin Biol Res 340C (1990) 93-100
    • (1990) Prog Clin Biol Res , vol.340 C , pp. 93-100
    • Penn, A.1
  • 367
    • 0017134206 scopus 로고
    • Implications of the monoclonal character of human atherosclerotic plaques
    • Benditt E. Implications of the monoclonal character of human atherosclerotic plaques. Beitr Pathol 158 (1976) 405-416
    • (1976) Beitr Pathol , vol.158 , pp. 405-416
    • Benditt, E.1
  • 368
    • 0000874922 scopus 로고
    • Evidence for a monoclonal origin of human atherosclerotic plaques
    • Benditt E., and Benditt J. Evidence for a monoclonal origin of human atherosclerotic plaques. Proc Natl Acad Sci USA 70 (1973) 1753-1756
    • (1973) Proc Natl Acad Sci USA , vol.70 , pp. 1753-1756
    • Benditt, E.1    Benditt, J.2
  • 369
    • 0042190658 scopus 로고    scopus 로고
    • Arterial smooth muscle cell heterogeneity: Implications for atherosclerosis and restenosis development
    • Hao H., Gabbiani G., and Bochaton-Piallat M. Arterial smooth muscle cell heterogeneity: Implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol 23 (2003) 1510-1520
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1510-1520
    • Hao, H.1    Gabbiani, G.2    Bochaton-Piallat, M.3
  • 370
    • 0030883928 scopus 로고    scopus 로고
    • Monoclonality of smooth muscle cells in human atherosclerosis
    • Murry C., Gipaya C., Bartosek T., Benditt E., and Schwartz S. Monoclonality of smooth muscle cells in human atherosclerosis. Am J Pathol 151 (1997) 697-705
    • (1997) Am J Pathol , vol.151 , pp. 697-705
    • Murry, C.1    Gipaya, C.2    Bartosek, T.3    Benditt, E.4    Schwartz, S.5
  • 371
    • 0017647792 scopus 로고
    • Effect of carcinogens on chicken atherosclerosis
    • Albert R., Vanderlaan M., Burns F., and Nishizumi M. Effect of carcinogens on chicken atherosclerosis. Cancer Res 37 (1977) 2232-2235
    • (1977) Cancer Res , vol.37 , pp. 2232-2235
    • Albert, R.1    Vanderlaan, M.2    Burns, F.3    Nishizumi, M.4
  • 372
    • 0024237754 scopus 로고
    • Arteriosclerotic plaque development is 'promoted' by polynuclear aromatic hydrocarbons
    • Penn A., and Snyder C. Arteriosclerotic plaque development is 'promoted' by polynuclear aromatic hydrocarbons. Carcinogenesis 9 (1988) 2185-2189
    • (1988) Carcinogenesis , vol.9 , pp. 2185-2189
    • Penn, A.1    Snyder, C.2
  • 373
    • 2142687748 scopus 로고
    • Tissue distribution of covalent DNA damage in mice treated dermally with cigarette 'tar': Preference for lung and heart DNA
    • Randerath E., Mittal D., and Randerath K. Tissue distribution of covalent DNA damage in mice treated dermally with cigarette 'tar': Preference for lung and heart DNA. Carcinogenesis 9 (1988) 75-80
    • (1988) Carcinogenesis , vol.9 , pp. 75-80
    • Randerath, E.1    Mittal, D.2    Randerath, K.3
  • 374
    • 0024535092 scopus 로고
    • Covalent DNA damage in tissues of cigarette smokers as determined by 32P-postlabeling assay
    • Randerath E., Miller R., Mittal D., Avitts T., Dunsford H., and Randerath K. Covalent DNA damage in tissues of cigarette smokers as determined by 32P-postlabeling assay. J Natl Cancer Inst 81 (1989) 341-347
    • (1989) J Natl Cancer Inst , vol.81 , pp. 341-347
    • Randerath, E.1    Miller, R.2    Mittal, D.3    Avitts, T.4    Dunsford, H.5    Randerath, K.6
  • 375
    • 0031717255 scopus 로고    scopus 로고
    • Putative susceptibility markers of coronary artery disease: Association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue
    • Van Schooten F., Hirvonen A., Maas L., De Mol B., Kleinjans J., Bell D., et al. Putative susceptibility markers of coronary artery disease: Association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue. FASEB J 12 (1998) 1409-1417
    • (1998) FASEB J , vol.12 , pp. 1409-1417
    • Van Schooten, F.1    Hirvonen, A.2    Maas, L.3    De Mol, B.4    Kleinjans, J.5    Bell, D.6
  • 376
    • 0031787207 scopus 로고    scopus 로고
    • Immunohistochemical detection of polycyclic aromatic hydrocarbon-DNA damage in human blood vessels of smokers and non-smokers
    • Zhang Y., Weksler B., Wang L., Schwartz J., and Santella R. Immunohistochemical detection of polycyclic aromatic hydrocarbon-DNA damage in human blood vessels of smokers and non-smokers. Atherosclerosis 140 (1998) 325-331
    • (1998) Atherosclerosis , vol.140 , pp. 325-331
    • Zhang, Y.1    Weksler, B.2    Wang, L.3    Schwartz, J.4    Santella, R.5
  • 378
    • 0032431634 scopus 로고    scopus 로고
    • Constitutive and inducible expression of cytochrome P450IA1 and P450IB1 in human vascular endothelial and smooth muscle cells
    • Zhao W., Parrish A., and Ramos K. Constitutive and inducible expression of cytochrome P450IA1 and P450IB1 in human vascular endothelial and smooth muscle cells. In Vitro Cell Dev Biol Anim 34 (1998) 671-673
    • (1998) In Vitro Cell Dev Biol Anim , vol.34 , pp. 671-673
    • Zhao, W.1    Parrish, A.2    Ramos, K.3
  • 379
    • 0031417971 scopus 로고    scopus 로고
    • Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes
    • Hammons G., Milton D., Stepps K., Guengerich F., Tukey R., and Kadlubar F. Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes. Carcinogenesis 18 (1997) 851-854
    • (1997) Carcinogenesis , vol.18 , pp. 851-854
    • Hammons, G.1    Milton, D.2    Stepps, K.3    Guengerich, F.4    Tukey, R.5    Kadlubar, F.6
  • 380
    • 0029758268 scopus 로고    scopus 로고
    • Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase
    • Shou M., Gonzalez F., and Gelboin H. Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase. Biochemistry 35 (1996) 15807-15813
    • (1996) Biochemistry , vol.35 , pp. 15807-15813
    • Shou, M.1    Gonzalez, F.2    Gelboin, H.3
  • 381
    • 0031815379 scopus 로고    scopus 로고
    • Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2
    • Turesky R., Constable A., Richoz J., Varga N., Markovic J., Martin M., et al. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2. Chem Res Toxicol 11 (1998) 925-936
    • (1998) Chem Res Toxicol , vol.11 , pp. 925-936
    • Turesky, R.1    Constable, A.2    Richoz, J.3    Varga, N.4    Markovic, J.5    Martin, M.6
  • 382
    • 0028020326 scopus 로고
    • Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans
    • Landi M., Bertazzi P., Shields P., Clark G., Lucier G., Garte S., et al. Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans. Pharmacogenetics 4 (1994) 242-246
    • (1994) Pharmacogenetics , vol.4 , pp. 242-246
    • Landi, M.1    Bertazzi, P.2    Shields, P.3    Clark, G.4    Lucier, G.5    Garte, S.6
  • 383
    • 0032908778 scopus 로고    scopus 로고
    • Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine
    • Sachse C., Brockmoller J., Bauer S., and Roots I. Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol 47 (1999) 445-449
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 445-449
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 384
    • 0036233709 scopus 로고    scopus 로고
    • Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes
    • Wang X., Greco M., Sim A., Duarte N., Wang J., and Wilcken D. Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes. Atherosclerosis 162 (2002) 391-397
    • (2002) Atherosclerosis , vol.162 , pp. 391-397
    • Wang, X.1    Greco, M.2    Sim, A.3    Duarte, N.4    Wang, J.5    Wilcken, D.6
  • 386
    • 0037838823 scopus 로고    scopus 로고
    • Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse
    • Smith A., Davies R., Dalton T., Miller M., Judah D., Riley J., et al. Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse. EHP Toxicogenomics 111 (2003) 45-51
    • (2003) EHP Toxicogenomics , vol.111 , pp. 45-51
    • Smith, A.1    Davies, R.2    Dalton, T.3    Miller, M.4    Judah, D.5    Riley, J.6
  • 387
    • 0036774272 scopus 로고    scopus 로고
    • Plasma levels of TNF-alpha and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure
    • Frye R., Schneider V., Frye C., and Feldman A. Plasma levels of TNF-alpha and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure. J Card Fail 8 (2002) 315-319
    • (2002) J Card Fail , vol.8 , pp. 315-319
    • Frye, R.1    Schneider, V.2    Frye, C.3    Feldman, A.4
  • 388
    • 6344240884 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction
    • Cornelis M., El-Sohemy A., and Campos H. Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction. J Med Genet 41 (2004) 758-762
    • (2004) J Med Genet , vol.41 , pp. 758-762
    • Cornelis, M.1    El-Sohemy, A.2    Campos, H.3
  • 389
    • 0035154274 scopus 로고    scopus 로고
    • Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: Implications for interindividual differences in nicotine metabolism
    • Oscarson M. Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: Implications for interindividual differences in nicotine metabolism. Drug Metab Dispos 29 (2001) 91-95
    • (2001) Drug Metab Dispos , vol.29 , pp. 91-95
    • Oscarson, M.1
  • 390
    • 33644851228 scopus 로고    scopus 로고
    • Altered CYP expression and function in response to dietary factors: Potential roles in disease pathogenesis
    • Murray M. Altered CYP expression and function in response to dietary factors: Potential roles in disease pathogenesis. Curr Drug Metab 7 (2006) 67-81
    • (2006) Curr Drug Metab , vol.7 , pp. 67-81
    • Murray, M.1
  • 391
    • 0027509520 scopus 로고
    • Sex differences in the diabetes-induced modulation of rat hepatic cytochrome P450 proteins
    • Barnett C., Rudd S., Flatt P., and Ioannides C. Sex differences in the diabetes-induced modulation of rat hepatic cytochrome P450 proteins. Biochem Pharmacol 45 (1993) 313-319
    • (1993) Biochem Pharmacol , vol.45 , pp. 313-319
    • Barnett, C.1    Rudd, S.2    Flatt, P.3    Ioannides, C.4
  • 392
  • 393
    • 0023914486 scopus 로고
    • Mechanism of induction of cytochrome P-450(ac) (P-450(j)) in chemically induced and spontaneously diabetic rats
    • Dong Z., Hong J., Ma Q., Li D., Bullock J., Gonzalez F., et al. Mechanism of induction of cytochrome P-450(ac) (P-450(j)) in chemically induced and spontaneously diabetic rats. Arch Biochem Biophys 263 (1988) 29-35
    • (1988) Arch Biochem Biophys , vol.263 , pp. 29-35
    • Dong, Z.1    Hong, J.2    Ma, Q.3    Li, D.4    Bullock, J.5    Gonzalez, F.6
  • 394
    • 0024559080 scopus 로고
    • Cytochrome P450 in livers of diabetic rats: Regulation by growth hormone and insulin
    • Yamazoe Y., Murayama N., Shimada M., Yamauchi K., and Kato R. Cytochrome P450 in livers of diabetic rats: Regulation by growth hormone and insulin. Arch Biochem Biophys 268 (1989) 567-575
    • (1989) Arch Biochem Biophys , vol.268 , pp. 567-575
    • Yamazoe, Y.1    Murayama, N.2    Shimada, M.3    Yamauchi, K.4    Kato, R.5
  • 395
    • 0023143955 scopus 로고
    • The induction of a specific form of cytochrome P-450 (P-450j) by fasting
    • Hong J., Pan J., and Gonzalez F. The induction of a specific form of cytochrome P-450 (P-450j) by fasting. Biochem Biophys Res Commun 142 (1987) 1077-1083
    • (1987) Biochem Biophys Res Commun , vol.142 , pp. 1077-1083
    • Hong, J.1    Pan, J.2    Gonzalez, F.3
  • 396
    • 0023900010 scopus 로고
    • Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: Regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies
    • Johansson I., Ekstrom G., Scholte B., Puzycki D., Jornvall H., and Ingelman-Sundberg M. Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: Regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies. Biochemistry 27 (1988) 1925-1934
    • (1988) Biochemistry , vol.27 , pp. 1925-1934
    • Johansson, I.1    Ekstrom, G.2    Scholte, B.3    Puzycki, D.4    Jornvall, H.5    Ingelman-Sundberg, M.6
  • 399
    • 0026523825 scopus 로고
    • Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet
    • Yun Y., Casazza J., Sohn D., Veech R., and Song B. Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet. Mol Pharmacol 41 (1992) 474-479
    • (1992) Mol Pharmacol , vol.41 , pp. 474-479
    • Yun, Y.1    Casazza, J.2    Sohn, D.3    Veech, R.4    Song, B.5
  • 400
    • 4544275379 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
    • Grundy S., Cleeman J., Merz C., Brewer Jr. H., Clark L., Hunninghake D., et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. J Am Coll Cardiol 44 (2004) 720-732
    • (2004) J Am Coll Cardiol , vol.44 , pp. 720-732
    • Grundy, S.1    Cleeman, J.2    Merz, C.3    Brewer Jr., H.4    Clark, L.5    Hunninghake, D.6
  • 401
    • 0037169960 scopus 로고    scopus 로고
    • Implications of cytochrome P450 interactions when prescribing medication for hypertension
    • Flockhart D., and Tanus-Santos J. Implications of cytochrome P450 interactions when prescribing medication for hypertension. Arch Intern Med 162 (2002) 405-412
    • (2002) Arch Intern Med , vol.162 , pp. 405-412
    • Flockhart, D.1    Tanus-Santos, J.2
  • 402
    • 30544450531 scopus 로고    scopus 로고
    • Pharmacogenomics of cholesterol-lowering therapy
    • Schmitz G., and Langmann T. Pharmacogenomics of cholesterol-lowering therapy. Vascul Pharmacol 44 (2006) 75-89
    • (2006) Vascul Pharmacol , vol.44 , pp. 75-89
    • Schmitz, G.1    Langmann, T.2
  • 403
    • 33646817773 scopus 로고    scopus 로고
    • Acute antiinflammatory properties of statins involve peroxisome proliferator-activated receptor-alpha via inhibition of the protein kinase C signaling pathway
    • Paumelle R., Blanquart C., Briand O., Barbier O., Duhem C., Woerly G., et al. Acute antiinflammatory properties of statins involve peroxisome proliferator-activated receptor-alpha via inhibition of the protein kinase C signaling pathway. Circ Res 98 (2006) 361-369
    • (2006) Circ Res , vol.98 , pp. 361-369
    • Paumelle, R.1    Blanquart, C.2    Briand, O.3    Barbier, O.4    Duhem, C.5    Woerly, G.6
  • 404
    • 0036852699 scopus 로고    scopus 로고
    • Stabilization of atherosclerotic plaques: New mechanisms and clinical targets
    • Libby P., and Aikawa M. Stabilization of atherosclerotic plaques: New mechanisms and clinical targets. Nat Med 8 (2002) 1257-1262
    • (2002) Nat Med , vol.8 , pp. 1257-1262
    • Libby, P.1    Aikawa, M.2
  • 405
    • 0035012075 scopus 로고    scopus 로고
    • Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes
    • Nakai D., Nakagomi R., Furuta Y., Tokui T., Ikeda T., Nishimura K., et al. Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. J Pharmacol Exp Ther 297 (2001) 861-867
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 861-867
    • Nakai, D.1    Nakagomi, R.2    Furuta, Y.3    Tokui, T.4    Ikeda, T.5    Nishimura, K.6
  • 406
    • 0034266349 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors: Assessing differences in drug interactions and safety profiles
    • Beaird S. HMG-CoA reductase inhibitors: Assessing differences in drug interactions and safety profiles. J Am Pharm Assoc (Wash DC: 1996). 40 (2000) 637-644
    • (2000) J Am Pharm Assoc (Wash DC: 1996). , vol.40 , pp. 637-644
    • Beaird, S.1
  • 408
    • 0035219105 scopus 로고    scopus 로고
    • New statins and new doses of older statins
    • Stein E. New statins and new doses of older statins. Curr Atheroscler Rep 3 (2001) 14-18
    • (2001) Curr Atheroscler Rep , vol.3 , pp. 14-18
    • Stein, E.1
  • 409
    • 0034046256 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors and myotoxicity
    • Ucar M., Mjörndal T., and Dahlqvist R. HMG-CoA reductase inhibitors and myotoxicity. Drug Saf 22 (2000) 441-457
    • (2000) Drug Saf , vol.22 , pp. 441-457
    • Ucar, M.1    Mjörndal, T.2    Dahlqvist, R.3
  • 410
    • 2942705774 scopus 로고    scopus 로고
    • Safety of statins: Focus on clinical pharmacokinetics and drug interactions
    • Bellosta S., Paoletti R., and Corsini A. Safety of statins: Focus on clinical pharmacokinetics and drug interactions. Circulation 109 (2004) III50-III57
    • (2004) Circulation , vol.109
    • Bellosta, S.1    Paoletti, R.2    Corsini, A.3
  • 411
    • 0035023185 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of fluvastatin
    • Scripture C., and Pieper J. Clinical pharmacokinetics of fluvastatin. Clin Pharmacokinet 40 (2001) 263-281
    • (2001) Clin Pharmacokinet , vol.40 , pp. 263-281
    • Scripture, C.1    Pieper, J.2
  • 413
    • 0346433752 scopus 로고    scopus 로고
    • CYP3A4 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin in primary hypercholesterolemia
    • Kajinami K., Brousseau M., Ordovas J., and Schaefer E. CYP3A4 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin in primary hypercholesterolemia. Am J Cardiol 93 (2004) 104-107
    • (2004) Am J Cardiol , vol.93 , pp. 104-107
    • Kajinami, K.1    Brousseau, M.2    Ordovas, J.3    Schaefer, E.4
  • 415
    • 8644235696 scopus 로고    scopus 로고
    • A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin
    • Ishikawa C., Anjo S., Ozaki H., Shirai K., Nakajima T., Inoue I., et al. A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin. J Hum Genet 49 (2004) 582-585
    • (2004) J Hum Genet , vol.49 , pp. 582-585
    • Ishikawa, C.1    Anjo, S.2    Ozaki, H.3    Shirai, K.4    Nakajima, T.5    Inoue, I.6
  • 416
    • 0035657076 scopus 로고    scopus 로고
    • Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerability of simvastatin
    • Mulder A., Van Lijf H., Bon M., Van den Bergh F., Touw D., Neef C., et al. Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerability of simvastatin. Clin Pharmacol Ther 70 (2001) 546-551
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 546-551
    • Mulder, A.1    Van Lijf, H.2    Bon, M.3    Van den Bergh, F.4    Touw, D.5    Neef, C.6
  • 417
    • 0042627731 scopus 로고    scopus 로고
    • Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers
    • Kirchheiner J., Kudlicz D., Meisel C., Bauer S., Meineke I., Roots I., et al. Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers. Clin Pharmacol Ther 74 (2003) 186-194
    • (2003) Clin Pharmacol Ther , vol.74 , pp. 186-194
    • Kirchheiner, J.1    Kudlicz, D.2    Meisel, C.3    Bauer, S.4    Meineke, I.5    Roots, I.6
  • 418
    • 85047684249 scopus 로고    scopus 로고
    • Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
    • Pullinger C., Eng C., Salen G., Shefer S., Batta A., Erickson S., et al. Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. J Clin Invest 110 (2002) 109-117
    • (2002) J Clin Invest , vol.110 , pp. 109-117
    • Pullinger, C.1    Eng, C.2    Salen, G.3    Shefer, S.4    Batta, A.5    Erickson, S.6
  • 419
    • 0032520266 scopus 로고    scopus 로고
    • Linkage between cholesterol 7α-hydroxylase and high plasma low-density lipoprotein cholesterol concentrations
    • Wang J., Freeman D., Grundy S., Cohen J., Guerra R., and Levine D. Linkage between cholesterol 7α-hydroxylase and high plasma low-density lipoprotein cholesterol concentrations. J Clin Invest 101 (1998) 1283-1291
    • (1998) J Clin Invest , vol.101 , pp. 1283-1291
    • Wang, J.1    Freeman, D.2    Grundy, S.3    Cohen, J.4    Guerra, R.5    Levine, D.6
  • 420
    • 3242736602 scopus 로고    scopus 로고
    • Interactions between common genetic polymorphisms in ABCG5/G8 and CYP7A1 on LDL cholesterol-lowering response to atorvastatin
    • Kajinami K., Brousseau M., Ordovas J., and Schaefer E. Interactions between common genetic polymorphisms in ABCG5/G8 and CYP7A1 on LDL cholesterol-lowering response to atorvastatin. Atherosclerosis 175 (2004) 287-293
    • (2004) Atherosclerosis , vol.175 , pp. 287-293
    • Kajinami, K.1    Brousseau, M.2    Ordovas, J.3    Schaefer, E.4
  • 422
    • 33646440029 scopus 로고    scopus 로고
    • Modulation of hepatic inflammatory risk markers of cardiovascular diseases by PPAR-{alpha} activators. Clinical and experimental evidence
    • Zambon A., Gervois P., Pauletto P., Fruchart J., and Staels B. Modulation of hepatic inflammatory risk markers of cardiovascular diseases by PPAR-{alpha} activators. Clinical and experimental evidence. Arterioscler Thromb Vasc Biol 26 (2006) 977-986
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 977-986
    • Zambon, A.1    Gervois, P.2    Pauletto, P.3    Fruchart, J.4    Staels, B.5
  • 424
    • 23644456172 scopus 로고    scopus 로고
    • Therapeutic roles of peroxisome proliferator-activated receptor agonists
    • Staels B., and Fruchart J. Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 54 (2005) 2460-2470
    • (2005) Diabetes , vol.54 , pp. 2460-2470
    • Staels, B.1    Fruchart, J.2
  • 425
    • 30344466045 scopus 로고    scopus 로고
    • Anti-atherogenic properties of fibrates may be largely due to their anti-inflammatory effects
    • Ye H., and Zhao S. Anti-atherogenic properties of fibrates may be largely due to their anti-inflammatory effects. Med Hypotheses 66 (2006) 495-500
    • (2006) Med Hypotheses , vol.66 , pp. 495-500
    • Ye, H.1    Zhao, S.2
  • 426
    • 33645559231 scopus 로고    scopus 로고
    • Therapeutical effects of PPAR agonists assessed by biomarker modulation
    • Chinetti-Gbaguidi G., Fruchart J., and Staels B. Therapeutical effects of PPAR agonists assessed by biomarker modulation. Biomarkers 10 Suppl. 1 (2005) S30-S36
    • (2005) Biomarkers , vol.10 , Issue.SUPPL. 1
    • Chinetti-Gbaguidi, G.1    Fruchart, J.2    Staels, B.3
  • 427
    • 31144477416 scopus 로고    scopus 로고
    • A new perspective in the treatment of dyslipidemia: Can fenofibrate offer unique benefits in the treatment of type 2 diabetes mellitus?
    • Steiner G. A new perspective in the treatment of dyslipidemia: Can fenofibrate offer unique benefits in the treatment of type 2 diabetes mellitus?. Treat Endocrinol 4 (2005) 311-317
    • (2005) Treat Endocrinol , vol.4 , pp. 311-317
    • Steiner, G.1
  • 428
    • 0035193202 scopus 로고    scopus 로고
    • Lipid-lowering trials in diabetes
    • Betteridge D. Lipid-lowering trials in diabetes. Curr Opin Lipidol 12 (2001) 619-623
    • (2001) Curr Opin Lipidol , vol.12 , pp. 619-623
    • Betteridge, D.1
  • 429
    • 84910144567 scopus 로고    scopus 로고
    • Triglycerides and coronary heart disease: Implications of recent clinical trials
    • Rubins H. Triglycerides and coronary heart disease: Implications of recent clinical trials. J Cardiovasc Risk 7 (2000) 339-345
    • (2000) J Cardiovasc Risk , vol.7 , pp. 339-345
    • Rubins, H.1
  • 430
    • 33644823630 scopus 로고    scopus 로고
    • Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation
    • Calkin A., Cooper M., Jandeleit-Dahm K., and Allen T. Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation. Diabetologia 49 (2006) 766-774
    • (2006) Diabetologia , vol.49 , pp. 766-774
    • Calkin, A.1    Cooper, M.2    Jandeleit-Dahm, K.3    Allen, T.4
  • 431
    • 0034711185 scopus 로고    scopus 로고
    • Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators
    • Delerive P., Gervois P., Fruchart J., and Staels B. Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators. J Biol Chem 275 (2000) 36703-36707
    • (2000) J Biol Chem , vol.275 , pp. 36703-36707
    • Delerive, P.1    Gervois, P.2    Fruchart, J.3    Staels, B.4
  • 432
    • 0141618465 scopus 로고    scopus 로고
    • Cell proliferation and apoptosis are altered in mice deficient in the NF-kappaB p50 subunit after treatment with the peroxisome proliferator ciprofibrate
    • Tharappel J., Nalca A., Owens A., Ghabrial L., Konz E., Glauert H., et al. Cell proliferation and apoptosis are altered in mice deficient in the NF-kappaB p50 subunit after treatment with the peroxisome proliferator ciprofibrate. Toxicol Sci 75 (2003) 300-308
    • (2003) Toxicol Sci , vol.75 , pp. 300-308
    • Tharappel, J.1    Nalca, A.2    Owens, A.3    Ghabrial, L.4    Konz, E.5    Glauert, H.6
  • 433
    • 85047684089 scopus 로고    scopus 로고
    • PPARalpha and GR differentially down-regulate the expression of nuclear factor-kappaB-responsive genes in vascular endothelial cells
    • Xu X., Otsuki M., Saito H., Sumitani S., Yamamoto H., Asanuma N., et al. PPARalpha and GR differentially down-regulate the expression of nuclear factor-kappaB-responsive genes in vascular endothelial cells. Endocrinology 142 (2001) 3332-3339
    • (2001) Endocrinology , vol.142 , pp. 3332-3339
    • Xu, X.1    Otsuki, M.2    Saito, H.3    Sumitani, S.4    Yamamoto, H.5    Asanuma, N.6
  • 434
    • 0037438377 scopus 로고    scopus 로고
    • Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation
    • Kleemann R., Gervois P., Verschuren L., Staels B., Princen H., and Kooistra T. Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation. Blood 101 (2003) 545-551
    • (2003) Blood , vol.101 , pp. 545-551
    • Kleemann, R.1    Gervois, P.2    Verschuren, L.3    Staels, B.4    Princen, H.5    Kooistra, T.6
  • 435
    • 16344383482 scopus 로고    scopus 로고
    • The effect of fenofibrate on the levels of high sensitivity C-reactive protein in dyslipidaemic hypertensive patients
    • Coban E., Ozdogan M., Yazicioglu G., and Sari R. The effect of fenofibrate on the levels of high sensitivity C-reactive protein in dyslipidaemic hypertensive patients. Int J Clin Pract 59 (2005) 415-418
    • (2005) Int J Clin Pract , vol.59 , pp. 415-418
    • Coban, E.1    Ozdogan, M.2    Yazicioglu, G.3    Sari, R.4
  • 436
    • 0242661386 scopus 로고    scopus 로고
    • Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: Relations with baseline lipid profiles
    • Wang T., Chen W., Lin J., Cheng C., Chen M., and Lee Y. Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: Relations with baseline lipid profiles. Atherosclerosis 170 (2003) 315-323
    • (2003) Atherosclerosis , vol.170 , pp. 315-323
    • Wang, T.1    Chen, W.2    Lin, J.3    Cheng, C.4    Chen, M.5    Lee, Y.6
  • 437
    • 0031843624 scopus 로고    scopus 로고
    • Liver-specific catalase expression in transgenic mice inhibits NF-kappaB activation and DNA synthesis induced by the peroxisome proliferator ciprofibrate
    • Nilakantan V., Spear B., and Glauert H. Liver-specific catalase expression in transgenic mice inhibits NF-kappaB activation and DNA synthesis induced by the peroxisome proliferator ciprofibrate. Carcinogenesis 19 (1998) 631-637
    • (1998) Carcinogenesis , vol.19 , pp. 631-637
    • Nilakantan, V.1    Spear, B.2    Glauert, H.3
  • 438
    • 0032484123 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging
    • Poynter M., and Daynes R. Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem 273 (1998) 32833-32841
    • (1998) J Biol Chem , vol.273 , pp. 32833-32841
    • Poynter, M.1    Daynes, R.2
  • 439
    • 0031909536 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of fibric acid derivatives (fibrates)
    • Miller D., and Spence J. Clinical pharmacokinetics of fibric acid derivatives (fibrates). Clin Pharmacokinet 34 (1998) 155-162
    • (1998) Clin Pharmacokinet , vol.34 , pp. 155-162
    • Miller, D.1    Spence, J.2
  • 440
    • 0037534010 scopus 로고    scopus 로고
    • Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance
    • Kyrklund C., Backman J., Neuvonen M., and Neuvonen P. Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance. Clin Pharmacol Ther 73 (2003) 538-544
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 538-544
    • Kyrklund, C.1    Backman, J.2    Neuvonen, M.3    Neuvonen, P.4
  • 441
    • 4644301418 scopus 로고    scopus 로고
    • Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: Analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil
    • Shitara Y., Hirano M., Sato H., and Sugiyama Y. Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: Analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil. J Pharmacol Exp Ther 311 (2004) 228-236
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 228-236
    • Shitara, Y.1    Hirano, M.2    Sato, H.3    Sugiyama, Y.4
  • 442
    • 29944446317 scopus 로고    scopus 로고
    • Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: Implications for drug-drug interactions
    • Ogilvie B., Zhang D., Li W., Rodrigues A., Gipson A., Holsapple J., et al. Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: Implications for drug-drug interactions. Drug Metab Dispos 34 (2006) 191-197
    • (2006) Drug Metab Dispos , vol.34 , pp. 191-197
    • Ogilvie, B.1    Zhang, D.2    Li, W.3    Rodrigues, A.4    Gipson, A.5    Holsapple, J.6
  • 444
    • 0036892714 scopus 로고    scopus 로고
    • Gemfibrozil inhibits CYP2c8-mediated cerivastatin metabolism in human liver microsomes
    • Wang J., Neuvonen M., Wen X., Backman J., and Neuvonen P. Gemfibrozil inhibits CYP2c8-mediated cerivastatin metabolism in human liver microsomes. Drug Metab Dispos 30 (2002) 1352-1356
    • (2002) Drug Metab Dispos , vol.30 , pp. 1352-1356
    • Wang, J.1    Neuvonen, M.2    Wen, X.3    Backman, J.4    Neuvonen, P.5
  • 445
    • 0033846824 scopus 로고    scopus 로고
    • Plasma concentrations of active simvastatin acid are increased by gemfibrozil
    • Backman J., Kyrklund C., Kivisto K., Wang J., and Neuvonen P. Plasma concentrations of active simvastatin acid are increased by gemfibrozil. Clin Pharmacol Ther 68 (2000) 122-129
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 122-129
    • Backman, J.1    Kyrklund, C.2    Kivisto, K.3    Wang, J.4    Neuvonen, P.5
  • 446
    • 0036918664 scopus 로고    scopus 로고
    • Gemfibrozil greatly increases plasma concentrations of cerivastatin
    • Backman J., Kyrklund C., Neuvonen M., and Neuvonen P. Gemfibrozil greatly increases plasma concentrations of cerivastatin. Clin Pharmacol Ther 72 (2002) 685-691
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 685-691
    • Backman, J.1    Kyrklund, C.2    Neuvonen, M.3    Neuvonen, P.4
  • 447
    • 17144423884 scopus 로고    scopus 로고
    • Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects
    • Lilja J., Backman J., and Neuvonen P. Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects. Br J Clin Pharmacol 59 (2005) 433-439
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 433-439
    • Lilja, J.1    Backman, J.2    Neuvonen, P.3
  • 448
    • 0038690424 scopus 로고    scopus 로고
    • Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000
    • Hajjar I., and Kotchen T. Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000. JAMA 290 (2003) 199-206
    • (2003) JAMA , vol.290 , pp. 199-206
    • Hajjar, I.1    Kotchen, T.2
  • 450
    • 0036788546 scopus 로고    scopus 로고
    • ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-2002-summary article: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina)
    • Braunwald E., Antman E., Beasley J., Califf R., Cheitlin M., Hochman J., et al. ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-2002-summary article: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina). Circulation 106 (2002) 1893-1900
    • (2002) Circulation , vol.106 , pp. 1893-1900
    • Braunwald, E.1    Antman, E.2    Beasley, J.3    Califf, R.4    Cheitlin, M.5    Hochman, J.6
  • 451
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • Chobanian A., Bakris G., Black H., Cushman W., Green L., Izzo Jr. J., et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 42 (2003) 1206-1252
    • (2003) Hypertension , vol.42 , pp. 1206-1252
    • Chobanian, A.1    Bakris, G.2    Black, H.3    Cushman, W.4    Green, L.5    Izzo Jr., J.6
  • 452
    • 2542421824 scopus 로고    scopus 로고
    • Variability in response to antihypertensive drug treatment
    • Materson B. Variability in response to antihypertensive drug treatment. Hypertension 43 (2004) 1166-1167
    • (2004) Hypertension , vol.43 , pp. 1166-1167
    • Materson, B.1
  • 453
    • 0019206754 scopus 로고
    • Clinical pharmacokinetics of metoprolol
    • Regardh C., and Johnsson G. Clinical pharmacokinetics of metoprolol. Clin Pharmacokinet 5 (1980) 557-569
    • (1980) Clin Pharmacokinet , vol.5 , pp. 557-569
    • Regardh, C.1    Johnsson, G.2
  • 455
    • 30544444526 scopus 로고    scopus 로고
    • Pharmacogenetics of antihypertensive treatment
    • Arnett D., Claas S., and Glasser S. Pharmacogenetics of antihypertensive treatment. Vasc Pharmacol 44 (2006) 107-118
    • (2006) Vasc Pharmacol , vol.44 , pp. 107-118
    • Arnett, D.1    Claas, S.2    Glasser, S.3
  • 456
    • 10044291653 scopus 로고    scopus 로고
    • Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension
    • Zineh I., Beitelshees A., Gaedigk A., Walker J., Pauly D., Eberst K., et al. Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension. Clin Pharmacol Ther 76 (2004) 536-544
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 536-544
    • Zineh, I.1    Beitelshees, A.2    Gaedigk, A.3    Walker, J.4    Pauly, D.5    Eberst, K.6
  • 457
    • 25844473190 scopus 로고    scopus 로고
    • Impact of CYP2D6 genotype on adverse effects during treatment with metoprolol: A prospective clinical study
    • Fux R., Morike K., Prohmer A., Delabar U., Schwab M., Schaeffeler E., et al. Impact of CYP2D6 genotype on adverse effects during treatment with metoprolol: A prospective clinical study. Clin Pharmacol Ther 78 (2005) 378-387
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 378-387
    • Fux, R.1    Morike, K.2    Prohmer, A.3    Delabar, U.4    Schwab, M.5    Schaeffeler, E.6
  • 458
    • 27344437084 scopus 로고    scopus 로고
    • Influence of CYP2D6 genotype on metoprolol plasma concentration and beta-adrenergic inhibition during long-term treatment: A comparison with bisoprolol
    • Nozawa T., Taguchi M., Tahara K., Hashimoto Y., Igarashi N., Nonomura M., et al. Influence of CYP2D6 genotype on metoprolol plasma concentration and beta-adrenergic inhibition during long-term treatment: A comparison with bisoprolol. J Cardiovasc Pharmacol 46 (2005) 713-720
    • (2005) J Cardiovasc Pharmacol , vol.46 , pp. 713-720
    • Nozawa, T.1    Taguchi, M.2    Tahara, K.3    Hashimoto, Y.4    Igarashi, N.5    Nonomura, M.6
  • 459
    • 0036808254 scopus 로고    scopus 로고
    • The CYP2C9 genotype predicts the blood pressure response to irbesartan: Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial
    • Hallberg P., Karlsson J., Kurland L., Lind L., Kahan T., Malmqvist K., et al. The CYP2C9 genotype predicts the blood pressure response to irbesartan: Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial. J Hypers 20 (2002) 2089-2093
    • (2002) J Hypers , vol.20 , pp. 2089-2093
    • Hallberg, P.1    Karlsson, J.2    Kurland, L.3    Lind, L.4    Kahan, T.5    Malmqvist, K.6
  • 460
    • 0034119823 scopus 로고    scopus 로고
    • In vitro inhibition screening of human hepatic P450 enzymes by five angiotensin-II receptor antagonists
    • Taavitsainen P., Kiukaanniemi K., and Pelkonen O. In vitro inhibition screening of human hepatic P450 enzymes by five angiotensin-II receptor antagonists. Eur J Clin Pharmacol 56 (2000) 135-140
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 135-140
    • Taavitsainen, P.1    Kiukaanniemi, K.2    Pelkonen, O.3
  • 461
    • 0032935655 scopus 로고    scopus 로고
    • Role of cytochrome P-4502C9 in irbesartan oxidation by human liver microsomes
    • Bourriè M., Meunier V., Berger Y., and Fabre G. Role of cytochrome P-4502C9 in irbesartan oxidation by human liver microsomes. Drug Metab Dispos 27 (1999) 288-296
    • (1999) Drug Metab Dispos , vol.27 , pp. 288-296
    • Bourriè, M.1    Meunier, V.2    Berger, Y.3    Fabre, G.4
  • 463
    • 13844315559 scopus 로고    scopus 로고
    • CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: A HuGEnet? Systematic review and meta-analysis
    • Sanderson S., Emery J., and Higgins J. CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: A HuGEnet? Systematic review and meta-analysis. Genet Med 7 (2005) 97-104
    • (2005) Genet Med , vol.7 , pp. 97-104
    • Sanderson, S.1    Emery, J.2    Higgins, J.3
  • 464
    • 3543028046 scopus 로고    scopus 로고
    • The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
    • Visser L., Hofman A., van Duijn C., Stricker B., Vulto A., van Schaik R., et al. The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon. Thromb Haemost 92 (2004) 61-66
    • (2004) Thromb Haemost , vol.92 , pp. 61-66
    • Visser, L.1    Hofman, A.2    van Duijn, C.3    Stricker, B.4    Vulto, A.5    van Schaik, R.6
  • 467
    • 29244482237 scopus 로고    scopus 로고
    • Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: Clinical relevance
    • Kirchheiner J., Roots I., Goldammer M., Rosenkranz B., Brockmöller J., et al. Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: Clinical relevance. Clin Pharmacokinet 44 (2005) 1209-1225
    • (2005) Clin Pharmacokinet , vol.44 , pp. 1209-1225
    • Kirchheiner, J.1    Roots, I.2    Goldammer, M.3    Rosenkranz, B.4    Brockmöller, J.5
  • 468
    • 21744439005 scopus 로고    scopus 로고
    • Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents
    • 60:103-106
    • Holstein A., Plaschke A., Ptak M., Egberts E., El-Din J., Brockmöller J., et al. Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents. Br J Clin Pharmacol (2005) 60:103-106
    • (2005) Br J Clin Pharmacol
    • Holstein, A.1    Plaschke, A.2    Ptak, M.3    Egberts, E.4    El-Din, J.5    Brockmöller, J.6
  • 469
    • 0032818309 scopus 로고    scopus 로고
    • Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone
    • Baldwin S., Clarke S., and Chenery R. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone. Br J Clin Pharmacol 48 (1999) 424-432
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 424-432
    • Baldwin, S.1    Clarke, S.2    Chenery, R.3
  • 470
    • 0034810107 scopus 로고    scopus 로고
    • Pharmacokinetics and clinical efficacy of pioglitazone
    • Hanefeld M. Pharmacokinetics and clinical efficacy of pioglitazone. Int J Clin Pract Suppl Suppl. 121 (2001) 19-25
    • (2001) Int J Clin Pract Suppl , vol.SUPPL. 121 , pp. 19-25
    • Hanefeld, M.1
  • 471
    • 0035169430 scopus 로고    scopus 로고
    • Hepatotoxicity with thiazolidinediones: Is it a class effect?
    • Scheen A. Hepatotoxicity with thiazolidinediones: Is it a class effect?. Drug Saf 24 (2001) 873-888
    • (2001) Drug Saf , vol.24 , pp. 873-888
    • Scheen, A.1
  • 472
    • 0032725398 scopus 로고    scopus 로고
    • Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes
    • Yamazaki H., Shibata A., Suzuki M., Nakajima M., Yokoi T., Shimada N., et al. Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes. Drug Metab Dispos 27 (1999) 1260-1266
    • (1999) Drug Metab Dispos , vol.27 , pp. 1260-1266
    • Yamazaki, H.1    Shibata, A.2    Suzuki, M.3    Nakajima, M.4    Yokoi, T.5    Shimada, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.